Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of spinosyn A to provide an additional ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and animal health markets.

Abstract: A handle for delivering, from a distal end of a catheter, a stent positioned within a sheath. The handle comprises an upper rack fixed to the handle and an upper distal block moveable along the upper rack and defining a pawl configured to permit only proximal movement in relation to the upper rack, further including an upper proximal block moveable along the upper rack and defining a pawl configured to permit only proximal movement in relation to the upper rack. The handle includes a lower rack configured to slide proximally and, alternatingly, distally in relation to the handle.

Abstract: Compositions and methods for isolating L-glufosinate from a composition comprising L-glufosinate and glutamate are provided. The method comprises converting the glutamate to pyroglutamate followed by the isolation of L-glufosinate from the pyroglutamate and other components of the composition to obtain substantially purified L-glufosinate. The composition comprising L-glufosinate and glutamate is subjected to an elevated temperature for a sufficient time to allow for the conversion of glutamate to pyroglutamate, followed by the isolation of L-glufosinate from the pyroglutamate and other components of the composition to obtain substantially purified L-glufosinate. The glutamate alternatively may be converted to pyroglutamate by enzymatic conversion. The purified L-glufosinate is present in a final composition at a concentration of 90% or greater of the sum of L-glufosinate, glutamate, and pyroglutamate.

Abstract: A cooktop appliance includes a gas burner. A primary control valve is coupled to the gas burner. The primary control valve is manually adjustable to regulate a flow of gaseous fuel to the gas burner. A secondary control valve is connected in series between the primary control valve and the gas burner. A controller is in communication with the secondary control valve. The controller is configured to receive a temperature measurement from a temperature sensor and to adjust the secondary control valve in response to the temperature measurement from the temperature sensor.

Abstract: Provided are methods for assessing samples to determine or to aid in determining Insulin Resistance and/or malfunctioning adipocytes. The methods involve analysis of non-esterified fatty acids (NEFAs) trafficking by determining kinetic parameters that include the fractional rate of NEFA appearance (Ra), the rate of NEFA disappearance (kNEFA), threshold for glucose-induced suppression (tG), and IC50 for glucose inhibition of NEFA production (glCso). Determining Ra for stearate that is similar to a control value, and/or a kNEFA for stearate that is higher than a control, indicates that the individual from whom the sample was taken has IR and/or adipocyte dysfunction. The method can include analysis of trafficking patterns for one or more of myristic, palmitic, palmitoleic, oleic, and linoleic acids, in addition to stearate. A determination of IR and/or adipocyte dysfunction can indicate that the individual is a candidate for treatment with an agonist of a peroxisome proliferator-activated receptor.

Abstract: A system for characterizing manual welding exercises and providing valuable training to welders that includes components for generating, capturing, and processing data. The data generating component further includes a fixture, workpiece, at least one calibration device having at least two point markers integral therewith, and a welding tool. The data capturing component further includes an imaging system for capturing images of the point markers and the data processing component is operative to receive information from the data capturing component and perform various position and orientation calculations.

Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of spinosyn A to provide an additional ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and animal health markets.

Abstract: A method for announcing impending critical events within a distributed storage environment is disclosed. In one embodiment, such a method analyzes, at a storage system, status of various storage system components to predict an impending critical event to occur at the storage system. Predicting the critical event may include calculating an amount of time before occurrence of the impending critical event. The method then communicates, from the storage system to a host system, over an in-band communication channel used to carry I/O traffic between the host system and the storage system, one or more of the impending critical event and the amount of time. This will ideally enable the host system to take mitigating actions before the critical event occurs. A corresponding system and computer program product are also disclosed.

Abstract: SCR-active molecular-sieve based catalysts with improved low-temperature performance are made by heating a molecular-sieve in a non-oxidizing atmosphere with steam (hydrothermal treatment), or in a reducing atmosphere without steam (thermal treatment), at a temperature in the range of 600-900° C. for a time period from 5 minutes to two hours. The resulting SCR-active iron-containing molecular sieves exhibit a selective catalytic reduction of nitrogen oxides with NH3 or urea at 250° C. that is at least 50% greater than if the iron-containing molecular-sieve were calcined at 500° C. for two hours without performing the hydrothermal or thermal treatment.

Abstract: Crystalline forms of N-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide (1) and its pharmaceutically acceptable salts and compositions thereof useful for the treatment or prevention of diseases or medical conditions mediated through mutated forms of epidermal growth factor receptor (EGFR), such as various cancers, are disclosed.

Abstract: Methods, computing systems and computer program products implement embodiments of the present invention that include initializing, by a hypervisor executing on a processor, first and second virtual machines. A first software application configured to provide a service is executed on the first virtual machine, and a logical data connection is established between the first and the second virtual machines. Examples of the logical connection include physical and virtual serial connections, and physical and virtual data networking connections. A second software application configured to enable remote monitoring of the first software application via the logical data connection is executed on the second virtual machine. In some embodiments, the second software application can remotely monitor the first software application via an interface such as a command line interface, a graphical user interface and an application programming interface.

Abstract: A cooktop appliance includes a gas burner. A primary control valve is coupled to the gas burner. The primary control valve is manually adjustable to regulate a flow of gaseous fuel to the gas burner. A secondary control valve is connected in series between the primary control valve and the gas burner. A controller is in communication with the secondary control valve. The controller is configured to receive a temperature measurement from a temperature sensor and to adjust the secondary control valve in response to the temperature measurement from the temperature sensor.

Abstract: Described are reverse engineering data analysis systems, and integrated circuit component data processing tools and methods thereof. A system can comprise: a data storage device operable to store a data structure comprising extracted IC component data nodes representative of corresponding IC components of target IC and a connectivity therebetween; a graphical user interface (GUI); and a digital data processor operable on said data structure to: render, via said GUI, a dynamic graph of said data nodes; graphically migrate at least some of said data nodes on said dynamic graph as a function of a connectivity thereof with other nodes, wherein connected nodes are attractively displaced relative to one another such that said migrating nodes progressively cluster with related nodes to define distinct IC component clusters representative of distinct groups of related IC components of the target IC, whereas unconnected notes are repulsively displaced so to progressively distance said unconnected nodes.

Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.

Abstract: A sizing caliper for facilitating the selection of a femoral component of a knee prosthesis includes a caliper body, two drill guide bodies, a stylus tower configured to be slidably linked to each other wherein as the caliper body and the stylus tower are linearly displaced at an equal rate relative to the drill guide body portions and the drill guide holes remain located at the midpoint of an anterior/posterior dimension defined by the distance between the tip of the stylus and the base portion. The caliper body comprises a base portion configured to couple and decouple from the caliper body using a sliding mechanism.

Abstract: A method of providing a medical image of a ROI of a patient, the method comprising: acquiring a first medical image of a region of interest (ROI) of a patient, the medical image characterized hy a first signal to noise ratio (SNR); determining for a given pixel in the first image a plurality of different first image patches in the first image, each having a pixel that is coincident with the given pixel; determining for each first image patch a similar second image patch having a second SNR greater than the first SNR; determining an enhanced pixel value for the given pixel having an enhanced SNR greater than the first SNR responsive to pixel values of pixels in the determined second image patches; and using the determined pixel value to generate a second medical image of the ROI having an enhanced SNR greater than the first SNR.

Abstract: SCR-active molecular-sieve based catalysts with improved low-temperature performance are made by heating a molecular-sieve in a non-oxidizing atmosphere with steam (hydrothermal treatment), or in a reducing atmosphere without steam (thermal treatment), at a temperature in the range of 600-900° C. for a time period from 5 minutes to two hours. The resulting SCR-active iron-containing molecular sieves exhibit a selective catalytic reduction of nitrogen oxides with NH3 or urea at 250° C. that is at least 50% greater than if the iron-containing molecular-sieve were calcined at 500° C. for two hours without performing the hydrothermal or thermal treatment.

Abstract: Systems and methods for delivering personalized content streams over a variety of devices and networks are disclosed. A user's preferences, customizations, and content are made available to the user through specialized clients for home, car, office, and portable environments. In order to enable personalized content streams on devices that are intermittently connected or that make use of network bandwidth during off-peak hours, the system prescribes a distributed content sequencing engine and a distributed, synchronized user profile and station/channel definitions. The system is also designed to support players connected via unidirectional or asymmetric connections such as satellite radios with or without an upstream data link.

Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.