Abstract: The present application relates to novel substituted heterocyclic carboxamides, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for producing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of breathing difficulties including sleep-induced breathing difficulties such as central and obstructive sleep apnoea, snoring (primary and obstructive snoring), dysphagia, peripheral and cardiac vascular disorders including diabetic microangiopathies and disorders of the peripheral and central nervous system including neurodegenerative and neuroinflammatory disorders.

Abstract: The invention relates to an apparatus for producing glass and to a process which can be executed with the apparatus.

Abstract: Techniques for providing a collaborative document in association with a virtual meeting on a communication platform are discussed herein. Users may communicate within the communication platform via text-based messages, which may include links, documents, videos, etc. Users may request a virtual meeting with audio and/or video capabilities. Responsive to a request, users within the communication channel may be invited to the virtual meeting and the collaborative document. The collaborative document can enable messaging and sharing functionalities attributable to a virtual space. The collaborative document may be populated with communications previously exchanged within the communication channel, such that links, documents, videos, content, etc. that occurred or were shared within the communication channel may be indicated within the collaborative document to provide context to the virtual meeting.

Abstract: Functional diagnosis of a vehicle component of a vehicle in production involves a vehicle-external first computing unit generating a diagnosis execution protocol. The diagnosis execution protocol includes machine-readable instructions for performing an at least semi-automated functional diagnosis of vehicle components by an in-vehicle computing unit. The diagnosis execution protocol is transferred to the in-vehicle computing unit of the vehicle in production. The diagnosis execution protocol is executed by the in-vehicle computing unit. The in-vehicle computing unit controls a vehicle component to check for correct functioning of the vehicle component. The response behavior of the vehicle component is captured automatedly by the in-vehicle computing unit or with manual assistance by a person supervising the production of the vehicle. The captured response behavior is output to the first computing unit external to the vehicle or a second computing unit external to the vehicle.

Abstract: A method of making a glass product includes the steps of: melting a batch of a plurality of glass raw materials in a melting tank to form a glass melt; heating at least one of the plurality of glass raw materials and the glass melt using at least one fuel burner by reacting hydrogen and oxygen; withdrawing the glass melt from the melting tank; obtaining a glass product, the glass product having an Fe2+ to Fe3+ ratio of less than 0.2 or less than 0.05 and having at least one of less than 80 bubbles in a size range of from 0.1 mm to 0.2 mm per 10 kg of glass and less than 2 bubbles of a size larger than 0.2 mm per 10 kg of a glass.

Abstract: Systems and methods are provided for a fuel delivery system. For example, the system includes a purge valve that is connected to a first channel providing fuel to the engine. A shutoff valve is connected to the purge valve via a second channel, the pressure through which can control activation of the purge valve. In activating the shutoff valve, a pressure at the second channel changes from a low pressure to a higher pressure, forcing the purge valve to close. This causes the purge valve to purge a volume of fluid into the first channel, such as in response to a fuel-off situation.

Abstract: Methods, systems, apparatuses, devices, and computer program products are described. A group-based communication system may support automatic layout updates for a document space. If a user adds an object into the document space, the system may generate a card representing the object. The card may include a link to a resource external to the document space and a preview image for the object, where the preview image may be rendered based on unfurling the link. The system may update a layout of the document space to include the generated card and may send, for display in a user interface (UI) of a user device, the updated layout. In some examples, a user may select to reposition the card within the UI (e.g., by dragging-and-dropping the card within the document space). The system may further update the layout of the document space based on the repositioning of the card.

Abstract: Techniques for transcribing and/or summarizing multimedia collaboration sessions are discussed herein. For example, users can communicate within a teleconferencing meeting associated with a channel. In some examples, a first machine learning model may be configured to receive audio-visual data and user interaction data (e.g., selected emojis, detected gestures, messages or text input by a user, a thread of messages, etc.) and output a teleconferencing meeting summary. In some examples, the teleconferencing meeting summary can include one or more highlights, action items, and/or artificial intelligence (AI) notes generated using a machine learning model(s).

Abstract: A glass element has, per kg of glass, 50 or fewer inclusions having a size of 2 ?m to 10 ?m. The glass element can be made of borosilicate glass.

Abstract: Techniques for transcribing and/or summarizing multimedia collaboration sessions are discussed herein. For example, users can communicate within a teleconferencing meeting associated with a channel. In some examples, a first machine learning model may be configured to receive audio-visual data and user interaction data (e.g., selected emojis, detected gestures, messages or text input by a user, a thread of messages, etc.) and output a teleconferencing meeting summary. In some examples, the teleconferencing meeting summary can include one or more highlights, action items, and/or artificial intelligence (AI) notes generated using a machine learning model(s).

Abstract: The present application relates to novel substituted heterocyclic carboxamides, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for producing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of breathing difficulties including sleep-induced breathing difficulties such as central and obstructive sleep apnoea, snoring (primary and obstructive snoring), dysphagia, peripheral and cardiac vascular disorders including diabetic microangiopathies and disorders of the peripheral and central nervous system including neurodegenerative and neuroinflammatory disorders.

Abstract: Snippets of content associated with a communication platform are described. In an example, based at least in part on a determination, by the communication platform, that a user of the communication platform is permitted to access one or more snippets of content provided by one or more other users of the communication platform, causing one or more user interface elements associated with the one or more snippets of content to be presented via a user interface of a user computing device of the user. The communication platform can receive, from the user computing device, a request to view a snippet of content of the one or more snippets of content and can cause the snippet of content to be presented by the user computing device via the user interface associated with the communication platform.

Abstract: Various examples are directed to systems, methods, and apparatuses for providing an interactive developer interface of a group-based communication system. Various examples are directed to systems, methods, and apparatuses for consolidating application data associated with an application within a group-based communication interface. Various examples are directed to systems, methods, and apparatuses for indexing processing actions associated with a plurality of applications.

Abstract: A method for biomechanical motion tracking records accelerometer and rate gyroscope data from a single inertial measurement unit mounted on the sacrum of a runner. Recorded resultant linear acceleration measurements and recorded angular velocity measurements about the anterior-posterior axis are processed to identify right foot impact events and left foot impact events. Impact events are identified using crackle, the third derivative of the resultant linear acceleration measurements. Left and right impact events are distinguished using the angular velocity measurements.

Abstract: The present invention relates to pharmaceutical dry powder formulations, comprising (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), preferably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid monohydrate (II) of formula (I-M-II) in combination with a lactose carrier, comprising lactose monohydrate as a mixture of coarse lactose and fine lactose, and to the process of manufacturing such pharmaceutical dry powder formulations and its application for use in the treatment of cardiopulmonary disorders, such as pulmonary arterial

Abstract: Functional diagnosis of a vehicle component of a vehicle in production involves a vehicle-external first computing unit generating a diagnosis execution protocol. The diagnosis execution protocol includes machine-readable instructions for performing an at least semi-automated functional diagnosis of vehicle components by an in-vehicle computing unit. The diagnosis execution protocol is transferred to the in-vehicle computing unit of the vehicle in production. The diagnosis execution protocol is executed by the in-vehicle computing unit. The in-vehicle computing unit controls a vehicle component to check for correct functioning of the vehicle component. The response behavior of the vehicle component is captured automatedly by the in-vehicle computing unit or with manual assistance by a person supervising the production of the vehicle. The captured response behavior is output to the first computing unit external to the vehicle or a second computing unit external to the vehicle.

Abstract: The present invention relates to novel diazabicyclically substituted imidazo[1,2-a]pyrimidine derivatives, to methods for producing the same, to the use thereof either alone or in combinations for the treatment and/or prevention of diseases, as well as to their use for preparing medicaments for the treatment and/or prevention of diseases, especially for treatment and/or prevention of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnoea and snoring.

Abstract: The disclosure relates to a glass product or glass composition, and to a method of making a glass product. The glass composition can be manufactured without inhomogeneities in the glass melt and with sufficiently uniform and isotropic properties in the obtained products. The glass compositions further minimise and/or overcome the problem of blockage of pipes, liners, ducts or nozzles during the manufacture of high-quality glasses.

Abstract: The present invention provides, among other things, compositions and methods for reducing oxidation of a complex comprising insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3), for treating diseases and complications of prematurity. In some embodiments, the methods comprise adding antioxidants. In some embodiments, the antioxidants are methionine or sodium thiosulfate. In some aspects, the compositions provided are stable, pure and potent compositions comprising IGF-1 and IGFBP-3. In some aspects, the formulation is lyophilized.

Abstract: The present invention relates to the use of (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), prefer-ably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(triflu-oromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid in form of monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl] [2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)-ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid inform of mono hydrate (II) of formula (I-M-II), in the inhalative treatment of car-diopulmonary and pulmonary disorders, such as pulmonary arterial hypertension (P AH), chronic tromboembolic pulmonary hyperten-sion (CTEPH) and pulmonary hypertension (PH) associated with chronic lung disease (PH group 3) such as pulmonary hypertension in chronic obstructive pu