Abstract: The present invention relates to ?2-Adrenoceptor subtype C (alpha-2C) antagonists, in particular aryl piperazines of formula (I) for the use in a method for the treatment and/or prophylaxis of sleep-related breathing disorders, preferably obstructive and central sleep apneas and snoring.

Abstract: An aerosol generator for generating an aerosol from a fluid, comprising: a vibratable membrane having a first side for being in contact with the fluid and an opposite second side, the membrane having a plurality of through holes penetrating the membrane in an extension direction from the first side to the second side, whereby the fluid passes the through holes from the first side to the second side when the membrane is vibrated for generating the aerosol at the second side, each through hole having along its extension direction a smallest diameter, a larger diameter that is larger than the smallest diameter and defined by that diameter that is closest to triple, preferably twice said smallest diameter, each through hole having a nozzle portion defined by that continuous portion of the through hole in the extension direction comprising the smallest diameter of the through hole and bordered by the larger diameter of the through hole, wherein the ratio of the total length of each through hole in the extension di

Abstract: Systems and methods provide managing of communication between a remote data object hosted by a remote resource and a group-based communication interface of a group-based communication system.

Abstract: Various examples are directed to systems, methods, and apparatuses for providing an interactive developer interface of a group-based communication system. Various examples are directed to systems, methods, and apparatuses for consolidating application data associated with an application within a group-based communication interface. Various examples are directed to systems, methods, and apparatuses for indexing processing actions associated with a plurality of applications.

Abstract: A joint has a housing with journal openings, an inner joint portion with a bearing area, which is fitted into the housing and extends axially out of the housing through the openings. A bearing body is arranged in and firmly connected to the housing which encloses the bearing body and comprises plastic. The inner joint portion is fitted and able to move within the body. Sealing bellows surround the inner joint portion and extend from a bearing-body-side bellows contact area, provided on the body or the housing, to an inner-joint-portion-side bellows contact area, provided on the inner joint portion. A sleeve is provided, on at least one of the bellows contact areas, that surrounds the inner joint portion and extends axially. The sleeve surrounds the bellows or is surrounded by the bellows, and has, at an axial end, a radial limb against which the bellows is axially supported.

Abstract: The present invention relates to novel diazabicyclically substituted imidazo[1,2-a]pyrimidine derivatives, to methods for producing the same, to the use thereof either alone or in combinations for the treatment and/or prevention of diseases, as well as to their use for preparing medicaments for the treatment and/or prevention of diseases, especially for treatment and/or prevention of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnoea and snoring.

Abstract: Various embodiments are directed to apparatuses, systems, and methods for authorizing within a group-based communication interface a bundled plurality of applications to be collectively installed in a group-based communication workspace enabling communications between client devices via a group-based communication system. Various embodiments are directed to apparatuses, systems, and methods for collectively installing within a group-based communication system a bundled plurality of applications associated with an application bundle. Various embodiments are directed to apparatuses, systems, and methods for generating within a group-based communication interface application bundle data associated with a plurality of applications.

Abstract: Embodiments of the present disclosure provide methods, systems, apparatuses, and computer program products for building and rendering a message user interface (UI) within a group-based communication interface of a group-based communication system, where the message UI is rendered to a client device based on a customizable block configuration and on customizable block data that is received from an external application.

Abstract: A firearm includes a sighting device with a sight line and a first device which detects a movement of the firearm in a horizontal plane, and a second device which alters a course of the sight line depending on the movement detected by the first device.

Abstract: Various examples are directed to systems, methods, and apparatuses for providing an interactive developer interface of a group-based communication system. Various examples are directed to systems, methods, and apparatuses for consolidating application data associated with an application within a group-based communication interface. Various examples are directed to systems, methods, and apparatuses for indexing processing actions associated with a plurality of applications.

Abstract: A test cell station (50) for at least one electrochemical test cell (10), comprising a housing (57), at least one receptacle (51) for the contacting insertion of at least one electrochemical test cell (10) and electrical connection means (54) for the electrical connection of a test cell (10) that has been inserted into the receptacle (51), characterized in that a thermally insulated temperature chamber (20) with a controllable cooling/heating device (27) for adjusting a temperature in the temperature chamber (20) is integrated into the test cell station (50), wherein the receptacle (51) is arranged in the test cell station (50) in such a way that the corresponding receptacle space for the electrochemical test cell (10) is arranged within the temperature chamber (20).

Abstract: Embodiments of the present disclosure provide methods, systems, apparatuses, and computer program products for building an rendering a message user interface (UI) within a group-based communication interface of a group-based communication system, where the message UI is rendered to a client device based on a customizable block configuration and on customizable block data that is received from an external application.

Abstract: The present application relates to novel (imidazo[1,2-a]pyridin-3-yl)methyl-substituted diazaheterobicyclic compounds, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory disorders including sleep-related respiratory disorders such as obstructive sleep apnoea and central sleep apnoea and snoring. The present application further relates to a method of discovering a compound having TASK-1-and/or TASK-3-blocking properties.

Abstract: The present disclosure describes a fuel system for an engine. The fuel system includes a fuel metering valve, a flow measuring system, and a controller in communication with the fuel metering valve and the flow measuring system. The fuel metering valve is operable to meter a flow rate of fuel based on a stroke of the fuel metering valve. The flow measuring system is configured to measure a mass flow rate of the fuel leaving the fuel system at a bandwidth greater than 20 Hz. The controller is configured to dynamically adjust the stroke of the fuel measuring system based on the mass flow rate of the fuel measured by the flow measuring system to change the flow rate of the fuel.

Abstract: The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.

Abstract: Embodiments of the present disclosure provide methods, systems, apparatuses, and computer program products for maintaining and updating a common message user interface (UI) shared among a plurality of group-based communication interfaces in a group-based communication system. The common message UI is rendered based on an updated version or a most up-to-date state of the common message UI when accessed by a client device associated with one of the plurality of group-based communication interfaces.

Abstract: The present application relates to novel 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring.

Abstract: A method for producing a glass product is provided. The method includes providing a glass melt; hot forming the glass melt to obtain a glass product; and transferring the glass melt from a first region to a second region through a tube. The tube has a part that protrudes with a length into the glass melt in the first region. The part being at a distance from an inner base lying directly thereunder. The length and the distance are configured so that little defective glass gets into the tube and is transferred to the second region.

Abstract: The present invention relates to a control device for controlling an operation of an aerosol nebulizer system (30), said aerosol nebulizer system (30) comprising an aerosol generator (31) for nebulizing a liquid and a plurality of sensor units (38a, 38b, 38c, 38d, 38e), said control device (20) comprising: a communication unit (21), configured to establish a wireless communication connection and to perform data transmission with the aerosol nebulizer system (30), a sensor data control unit (22), configured to trigger a selection of sensor data related to the sensor units (38a, 38b, 38c, 38d, 38e) to be wirelessly transmitted to the control device (20).

Abstract: This patent discloses methods, systems and computer program product for producing optimal search requests based on certain user queries and on certain user specific data. The patent describes in detail of a software system encapsulated in the form of a search engine, using the process of serendipity in network systems (digitally) and drawing data from previous user searches, user data, user specifics, and potentially utilize the data and results for more lucrative job-related opportunities. This patent describes in detail the mathematical functions, the predictive programming, the binary network formation, and the storage of constantly evolving data into one system and its manipulation for user directed searches and user beneficial results.