Abstract: The invention relates to compounds of formula (I) and their salts and stereoisomers in which the variables are as defined in the description and claims, for producing medicaments used in the treatment of cardiovascular and other diseases. Such compounds, processes for preparing them, compositions containing them, and methods of using them are claimed.

Abstract: A switch contact arrangement for a power switch is provided with a device for increasing the contact force acting between switch contacts. The device includes a cavity which is made in a stationary conductive element of the switch contact arrangement in such a manner that the direction of the current in the conductive element adjacent to the stationary switch contact runs essentially perpendicular to the longitudinal direction of the conductive element and therefore essentially parallel to the direction of current in an associated displaceable conductive element. The above-mentioned arrangement is suitable for low-voltage power switches with a selective form, whereby the switch contacts thereof allow a short-circuit current to be guided without premature opening.

Abstract: A mechano-electrical fuse (10) for a hand grenade (76), which has a spring element for the storage of mechanical energy and which has a drive device connected to the spring element for driving an electrical generator (28) through mechanical energy which is stored in the spring element. The electrical generator (28) is connected through an electronic delay circuit (56) with a detonator (46), with which a booster charge (48) is associated. A barrier (40) is provided between the detonator (46) and the booster charge (48). The spring element is formed by a tensioning spring (24) associated with the handle lever (18) of the hand grenade (76). The drive device has a taut cable line (68) which is fixed at one end (70) to the generator shaft (30) and wound with a number of turns (72) around the generator shaft (30). The second end (74) of the cable line (68) is mounted to the handle lever (18).

Abstract: A device for detecting wear of switching contacts in an electric switch appliance is disclosed, the wear of the contacts being caused at least at a pair of switching contacts appliance. The device includes a lightwave guide and a detector. A light exiting from at least one light source is capable of being injected into the lightwave guide and guided by the lightwave guide up to the detector. The lightwave guide is arranged relative to the pair(s) of switching contacts, such that the intensity of the light injected in the lightwave guide, which is measured by the detector, decreases in the switching appliance as the number of wear particles of contacts generated by the wear of the contacts increases.

Abstract: The invention relates to a method for building a tire casing on a tire building drum for a self-supporting radial tire, wherein the tire casing comprises an inner layer, reinforcing profiles for side walls as well as side walls, at least one casing ply and bead areas and wherein the tire building drum is provided with surrounding pockets for receiving the reinforcing profiles, characterized in that the regions of the reinforcing profiles (9) coming into contact with the inner layer (4) are provided with a groove structure, which comprises a plurality of grooves (12) extending in a continuous manner, in particular transverse to the circumferential direction of the tire building drum (10).

Abstract: The invention provides an isolated nucleic acid molecule encoding the polypeptide having galacturonosyltransferase (GaIAT) activity. The GALA T 1 disclosed represents the first pectin biosynthetic glycosyltransferase gene isolated from plants. The invention further provides 14 GALAT and 10 GALAT-like gene superfamily members. The identification of the GALAT gene superfamily offers new opportunities to modulate pectin synthesisin vivo and in vitro by modulating the GALATgene, for example, transgenic plants that produce modified pectins can be generated by altering the GALAT gene. Since modified pectins are predicted to affect plant growth, development, and plant defense responses, the transgenic plants are expected to have improved agricultural value. The modified pectins isolated from such transgenic plants are useful as gelling and stabilizing agents in the food, neutraceutical, and pharmaceutical industries.

Abstract: This invention relates to methods for treating cardiovascular disorders selected from heart failure, thromboembolic disorders, venous diseases, and fibriotic disorders other than fibrosis of the liver, comprising administering an effective amount of a compound of formula (I) wherein the several variables are as defined in the specification and claims.

Abstract: The invention relates to a contact arrangement for a vacuum switch tube for low-voltage power switches. The aim of the invention is to reduce the contact force required to control short circuit currents. To this end, a twin-contact contact arrangement is used wherein every contact comprises a plurality of separate individual contacts having a defined spring rate. At least one of the contact bodies (4) is configured as a two-layer spiral contact with a lower layer consisting of a highly elastic material and an upper layer (7) consisting of a highly electroconductive material. A contact coat (9) consisting of a contact material is provided on the upper layer in the outer zone of every contact arm (10).

Abstract: This invention relates to methods for treating cardiovascular disorder selected from heart failure, thromboembolic disorders, venous diseases, and fibrotic disorders other than fibrosis of the liver, comprising administering an effective amount of a compound of formula (I) in which the several variables are as defined in the specification and claims.

Abstract: The invention relates to compounds of the general formula (I) wherein R1 represents H, halogen, or OCF3; R2 and R3 each represents H or halogen; R4 represents C1-6-alkyl, C3-8-cycloalkyl, CF3, OCF3, F, Cl, OMe, or optionally substituted phenyl; V represents O, CH2O, OCF2, or O—C1-6-alkyl-O; and W represents CH2 or CH2CH2. A process for making such compounds, pharmaceutical compositions containing them, and methods of treatment of various conditions using them are also disclosed and claimed.

Abstract: Compounds of the general formula (I) wherein R1 represents halogen, R2 represent H or halogen, and R3 represents C3-8-cycloalkyl, C3-8-cycloalkenyl, or optionally substituted phenyl, pharmaceutical compositions containing such material, and methods of using such materials in the treatment of various diseases are disclosed and claimed.

Abstract: Described is a mechano-electrical fuse (10) for a hand grenade (76), which has a spring element for the storage of mechanical energy and which has a drive device connected to the spring element for driving an electrical generator (28) by means of the mechanical energy stored in the spring element. The electrical generator (28) is connected together by way of an electronic delay circuit (56) with a detonator (46), with which a booster charge (48) is associated. A barrier (40) is provided between the detonator (46) and the booster charge (48). The spring element is formed by the tensioning spring (24) associated with the handle lever (18) of the hand grenade (76). The drive device has a taut cable line (68) which is fixed with its one end (70) to the generator shaft (30) and wound with a number of turns (72) around the generator shaft (30). The second end (74) of the cable line (68) is mounted to the handle lever (18).

Abstract: A new vacuum switching chamber is intended for power breakers in the low-voltage range and is distinguished by a compact form with a small physical height and a high switching capacity. Its enclosure includes a plate-like power current connection, a cylindrical wall part which surrounds flat spiral contacts, an annular insulator and a membrane disk with a centrally arranged power current supply bolt.

Abstract: The invention relates to a switch contact arrangement (2) for a power switch (1) provided with a device for increasing the contact force acting between switch contacts (7, 16). The device comprises a cavity (24) which is made in a stationary conductive element (3) of the switch contact arrangement (2) in such a manner that the direction of the current in the conductive element (3) adjacent to the stationary switch contact (7) runs essentially perpendicular to the longitudinal direction of the conductive element (3) and therefore essentially parallel to the direction of current in an associated displaceable conductive element (12). The above-mentioned arrangement is suitable for low-voltage power switches with a selective form, whereby the switch contacts (7, 16) thereof allow a short-circuit current to be guided without premature opening.

Abstract: The invention relates to novel tetrahydroquinoxalines and processes for their preparation, their use for the treatment and/or the prophylaxis of diseases, in particular for the treatment and/or prophylaxis of states of pain.

Abstract: The invention relates to compounds of formula (I), to salts and stereoisomers thereof, to their production and to their use for producing medicaments used for treating cardiovascular diseases.

Abstract: A remote service system for a circuit breaker fixed in a remote allocation. Remote service is provided by any station that can be accessed through a communication network. The system is provided, on one side, with a diagnostic hand-held apparatus which is dedicated to a switch service and should be connected, if necessary, to a circuit breaker, through a connecting unit provided to that end, and on the other side, with a telecommunication interface for exchanging a data through a telecommunication network.

Abstract: The present invention provides a method of testing micro-electrical mechanical mirrors including simultaneously applying a voltage to each of a plurality of such mirrors to tilt each of the plurality to a deflection angle, and simultaneously deflecting a beam from each of the plurality using an interferometer to simultaneously determine an accuracy of the deflection angle of each of the plurality. In addition, a method of manufacturing micro-electrical mechanical mirrors is also disclosed.

Abstract: The invention relates to compounds of formula (I), to a method for their production and to their use as medicaments.

Abstract: The invention relates to the use of compounds of formula (I) and of their salts and stereoisomers for producing medicaments used in the treatment of cardiovascular diseases.