Patents by Inventor Michael Horstmann

Michael Horstmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5827245
    Abstract: A transdermal therapeutic system containing the active substance 17-.beta.-estradiol and optionally further active substances has a laminated structure positioned on a backing layer which is essentially impermeable to active substance and moisture, at least one matrix layer and optionally an adhesive layer. The at least one matrix layer or the adhesive layer contains anhydrous 17-.beta.-estradiol in crystalline form.
    Type: Grant
    Filed: May 9, 1997
    Date of Patent: October 27, 1998
    Assignee: LTS Lohmann Therapie-Systeme GmbH & Co. KG
    Inventors: Michael Horstmann, Marion Kursawe, Horst Dzekan
  • Patent number: 5716636
    Abstract: Transdermal therapeutic system comprising the active substance acetylsalicylic acid, having a layered structure consisting of a backing layer which is substantially impermeable to active substances and moisture and one or several active substance-containing matrix layers, which is characterized in that at least one of said matrix layers comprises acetylsalicylic acid in mainly crystalline form.
    Type: Grant
    Filed: July 15, 1996
    Date of Patent: February 10, 1998
    Assignee: LTS Lohmann Therapie-Systeme GmbH
    Inventors: Michael Horstmann, Gerd Hoffmann, Heinrich Kindel
  • Patent number: 5702721
    Abstract: A transdermal therapeutic system exhibiting layered structure consists of a backing layer which is impermeable to active substances, a matrix having water-insoluble basic material and islands (inclusions) divided therein, and a layer controlling the access of cutaneous liquid by means of which the matrix is activatable. Process for the production are described.
    Type: Grant
    Filed: August 30, 1994
    Date of Patent: December 30, 1997
    Assignee: LTS Lohmann Therapie-Systeme GmbH & Co. KG
    Inventors: Michael Horstmann, Fritz Herrmann
  • Patent number: 5685837
    Abstract: A transdermal therapeutic system which is composed of layers exhibits an electrically insulating backing layer (1) being impermeable to active substances, and two galvanic elements which are positioned in separation from each other. The skin-facing electrodes of the galvanic elements have layers thereon consisting of a liquid absorbing material becoming ionically conductive after liquid admission. The layer of at least one of the dermad electrodes comprises a pharmaceutical active substance.
    Type: Grant
    Filed: May 7, 1991
    Date of Patent: November 11, 1997
    Assignee: LTS LohmannTherapie-Systeme GmbH & Co. KG
    Inventor: Michael Horstmann
  • Patent number: 5629003
    Abstract: A presentation which, in the form of a film, permits the individual dosage of drugs, confectionary, other food, cosmetics and the like for oral application or intake. The presentation is characterized by the fact that it comprises a mass of 20 to 60%-wt. of at least a film former, 2 to 40%-wt. of at least a gel former, 0.1 to 35%-wt. of at least an active substance, and up to 40%-wt. of an inert filling agent, being applied on a carrier, or by consisting of a mass having the aforementioned composition but is unsupported. In the production thereof, an intimate mixture of said components is prepared, optionally with the addition of up to 30%-wt. of a polar solvent, and processed to form a homogeneous, spreadable or extrudable mass.
    Type: Grant
    Filed: September 2, 1994
    Date of Patent: May 13, 1997
    Assignee: LTS Lohmann Therapie-Systeme GmbH & Co. KG
    Inventors: Michael Horstmann, Wolfgang Laux, Stefan Hungerbach
  • Patent number: 5254348
    Abstract: The present invention relates to a transdermal therapeutic system with tulobuterol or one of the pharmaceutically acceptable salts thereof as active substance, comprising a backing layer which is substantially impermeable to active substances and at least one matrix layer which contains the active substance, which matrix layer comprises at least one styrene-1,3-diene-styrene block copolymer. The present invention is further directed to a process for the production of said transdermal therapeutic system.
    Type: Grant
    Filed: January 28, 1991
    Date of Patent: October 19, 1993
    Assignee: LTS Lohmann Therapie Systeme GmbH & Co. KG
    Inventors: Hans R. Hoffmann, Michael Horstmann
  • Patent number: 5230898
    Abstract: A transdermal therapeutic system exhibiting layered structure consists of a backing layer which is impermeable to active substances, a matrix having water-insoluble basic material and islands (inclusions) divided therein, and a layer controlling the access of cutaneous liquid by means of which the matrix is activatable. Process for the production are described.
    Type: Grant
    Filed: March 28, 1990
    Date of Patent: July 27, 1993
    Assignee: LTS Lohmann Therapie-Systeme GmbH & Co. K.G.
    Inventors: Michael Horstmann, Fritz Herrmann
  • Patent number: 4882163
    Abstract: Transdermal therapeutic system for administration of moxonidine, containing at least one higher n-alkane-carboxylic acid with at least 12 C atoms as a permeation accelerator.
    Type: Grant
    Filed: August 1, 1988
    Date of Patent: November 21, 1989
    Assignee: Beiersdorf Aktiengesellschaft
    Inventors: Gunter Guse, Michael Horstmann, Axel Erler