Abstract: An Ising machine system comprises a plurality of capacitors, a plurality of resistors having first and second terminals, wherein each capacitor is electrically connected to the first or second terminal of at least one resistor of the plurality of resistors via each of its positive and negative terminals, a power supply having positive and negative rails, a switching network configured to initialize each of the plurality of capacitors with a positive or negative voltage from the power supply, then disconnect all of the plurality of capacitors from the power supply, allowing the capacitor voltages to float, and at least one voltage measuring device configured to measure a voltage across the positive and negative terminals of a capacitor of the plurality of capacitors. A method of running an Ising machine system is also disclosed.

Abstract: Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.

Abstract: Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.

Abstract: Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.

Abstract: Systems and methods for tracking inventory items in an area of real space are disclosed. The methods can include receiving a signal generated in dependence on sensors, and detecting an item in the area of real space based on the received signal. One method includes implementing a trained location detection model to determine, based on inputs, whether an inventory item identified in the portion of the image has changed a position in the area of real space. Another method includes implementing a trained size determination model to determine, based on inputs, the size of an inventory item detected in the area of real space.

Abstract: A water splashing toy includes an outer shell having an inner cavity and a plurality of water passages communicated to the inner cavity, and an inner water retaining bladder disposed in the inner cavity of the outer shell. The water splashing toy is easy and convenient for quick water filling, and the toy bounces well on a user body and does not explode, so that the user will not get hurt or feel pain when playing the water splashing toy.

Abstract: A tool includes an elongated shaft and a socket positioning assembly disposed on the shaft. A rear end portion of the shaft is configured to be mounted for rotation by a hand tool or a power tool. The shaft is configured to support a first socket and a second socket. Each socket is selectively positionable on the shaft in either a use configuration or in a storage configuration. The socket positioning assembly includes a socket support member configured to support the first socket in its use configuration proximate the front end portion of the shaft, and a socket retainer configured to retain at least the second socket in its storage configuration on the shaft. The storage configuration is between the socket retainer and the rear end portion of the shaft. The socket retainer is positioned between the first socket and the second socket.

Abstract: Systems and methods for tracking inventory items in an area of real space are disclosed. The method includes receiving a signal generated in dependence on sensors. The signal indicates a change to a portion of an image of an area of real space. The method includes, in response to receiving the signal, implementing a trained location detection model to determine, based on inputs, whether an inventory item identified in the portion of the image has changed a position in the area of real space. The method includes implementing a trained item classification model to determine a classification of the inventory item. The method includes updating an inventory database with inventory item data determined in dependence on the classification of the inventory item to provide an updated map of the area of real space as a result of the received signal indicating the change to the portion of the image.

Abstract: Devices are provided with integration for half a VCSEL to a top mirror, with the heterogeneous integration of a half-VCSEL to a Si sub mount.

Abstract: A transceiver module includes a VCSEL laser with one or more active regions having quantum wells and barriers. The one or more active regions are surrounded by one or more p-n junctions. The one or more active regions can include a selected shape structure, one or more tunnel junctions (TJ), one or more apertures with the selected shape structure, one or more buried tunnel junctions (BTJ) or oxide confine apertured. Additional TJ's, planar structures and or additional BTJ's are created during a regrowth process that is independent of a first growth process. The VCSEL laser has an HCG grading and a bottom DBR. The transceiver module is configured to convert optical signals into electrical signals.

Abstract: An SOA is coupled to an optical fiber including a tunable VCSEL laser with one or more active regions having quantum wells and barriers. The one or more active regions are surrounded by one or more p-n junctions. The one or more active regions can include a selected shape structure, and one or more tunnel junctions (TJ). One or more apertures are provided with the selected shape structure, one or more buried tunnel junctions (BTJ) or oxide confine apertured, additional TJ's, planar structures and or additional BTJ's created during a regrowth process that is independent of a first growth process,. the VCSEL having an HCG grading. An optical fiber is included as is at least one of an ASIC and driver controller coupled to the VCSEL laser.

Abstract: An (SOA) system includes a tunable VCSEL laser with one or more active regions having quantum wells and barriers. The one or more active regions are surrounded by one or more p-n junctions. The one or more active regions can include a selected shape structure, one or more tunnel junctions (TJ), one or more apertures provided with the selected shape structure, one or more buried tunnel junctions (BTJ) or oxide confine apertured, additional TJ's, planar structures and or additional BTJ's created during a regrowth process that is independent of a first growth process, the VCSEL having an HCG grading. At least one of an ASIC and driver controller coupled to the VCSEL laser, the ASIC monitoring an output of a light pulse over wavelength.

Abstract: Provided are high concentration stable formulations of anti-CSF1R/CSF1 antibodies. An example formulation includes 105 to 250 mg/mL of the antibody, 100 mM to 200 mM of arginine glutamate or arginine HCl, 10 mM to 50 mM histidine, and 0.015 to 0.035 w/v % of polysorbate 80, at a pH of 5.4 to 5.6. Also provided are methods of using the formulations for treating diseases.

Abstract: An (SOA) system includes a tunable VCSEL laser with one or more active regions having quantum wells and barriers. The one or more active regions are surrounded by one or more p-n junctions. The one or more active regions can include a selected shape structure, one or more tunnel junctions (TJ), one or more apertures provided with the selected shape structure, one or more buried tunnel junctions (BTJ) or oxide confine apertured, additional TJ's, planar structures and or additional BTJ's created during a regrowth process that is independent of a first growth process, the VCSEL having an HCG grading. At least one of an ASIC and driver controller coupled to the VCSEL laser, the ASIC monitoring an output of a light pulse over wavelength.

Abstract: A water splashing toy includes an outer shell having an inner cavity and a plurality of water passages communicated to the inner cavity, and an inner water retaining bladder disposed in the inner cavity of the outer shell. The water splashing toy is easy and convenient for quick water filling, and the toy bounces well on a user body and does not explode, so that the user will not get hurt or feel pain when playing the water splashing toy.

Abstract: Provided are high concentration stable formulations of anti-CSF1R/CSF1 antibodies. An example formulation includes 105 to 250 mg/mL of the antibody, 100 mM to 200 mM of arginine glutamate or arginine HCl, 10 mM to 50 mM histidine, and 0.015 to 0.035 w/v % of polysorbate 80, at a pH of 5.4 to 5.6. Also provided are methods of using the formulations for treating diseases.

Abstract: A scalable Ising machine system comprises a plurality of chips, each chip comprising a plurality of N nodes, each node comprising a capacitor, a positive terminal, and a negative terminal, a plurality of N×M connection units, arranged in N rows and M columns, each connection unit comprising a set of reconfigurable resistive connections, each connection unit configurable to connect a pair of the N nodes via the reconfigurable resistive connections, and a plurality of interconnects, wherein each chip of the plurality of chips is communicatively connected all other chips of the plurality of chips via at least one interconnect. A method of calculating a Hamiltonian of a system of coupled spins is also disclosed.

Abstract: The present invention provides novel pharmaceutical compositions comprising -(4-Chloro-2-(morpholin-4-yl)thiazol-5-yl)-7-(1-ethylpropyl)-2,5-dimethylpyrazolo(1,5-a)pyrimidine and methods of using the same for the treatment of Congenital adrenal hyperplasia (CAH).

Abstract: Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.

Abstract: Patients with congenital adrenal hyperplasia (CAH) need adequate care and treatment in order to lead normal lives. Hence, there is a need for new methods of treating CAH. This disclosure provides new compounds, salts, compositions and uses thereof in the treatment of CAH.