Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, and methods of making and using the foregoing.

Abstract: The present invention relates to binding proteins having tethered light chains and methods of making and using them.

Abstract: A flexible pipe body and method of manufacturing a flexible pipe body are disclosed. The flexible pipe body includes a fluid retaining layer for preventing ingress of fluid into the flexible pipe body from an environment outside of the flexible pipe body; and a fibre element arranged generally along a longitudinal axis of the fluid retaining layer.

Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, methods of making and using the foregoing, and methods of alleviating pain with peptide inhibitors of Nav1.7.

Abstract: Methods, systems and apparatuses are disclosed for approximating vertical and horizontal correction values in a pixel value correction calculation. Multiple vertical and/or horizontal correction curves are used and may be employed for one or more color channels of the imager. The use of multiple correction curves allows for a more accurate approximation of the correction curves for image pixels.

Abstract: One embodiment of the present disclosure relates to a method that includes sending a negotiating message from a user to one or more invitees using a messaging protocol, the negotiating message comprising one or more plans for a meeting, each plan including a time information and a location information for the meeting. The method further includes receiving, using the messaging protocol, one or more responses from the one or more invitees, the one or more responses indicating an approval or rejection of the one or more plans and determining based at least partially on the one or more responses received from the one or more invitees to book the event based on the received responses from the one or more invitees.

Abstract: The present invention relates to potato virus NIa protease variants or fragments thereof, polynucleotides encoding them, and methods of making and using the foregoing.

Abstract: A foot operable percussion instrument producing jingling sounds similar to a tambourine is useable by a solo performer and possesses a wedge-shaped body with an inclined striking surface for the striking by a foot or a portion thereof. The wedge-shaped body is connected to a base plate member by a pair of rigid connectors that together define a fulcrum so that the front portion of the wedge-shaped block pivots downwardly when struck by a foot on the inclined striking surface and rights itself when the foot is lifted. The jingling sound produced is of short duration.

Abstract: An electrical box insert device is disclosed that provides users with an easy way to terminate power to pot lights and electrical devices. The electrical box insert device comprises a housing sized to be inserted into an existing electrical box. A sheathed electrical cable is inserted through an opening of the housing and secured to a conductive bus bar continuatively connecting cables and/or terminating power to an electrical box. Typically, a user manually strips the outer sheath of the cables and the conductor sheath, exposing the conductors. The exposed conductors can then be secured to the conductive bus bar continuatively connecting cables. Furthermore, an electrical outlet can be secured via a sheathed electrical cable to the conductive bus bar continuatively connecting cables.

Abstract: Methods, apparatuses and systems providing pixel correction values for a captured image, where the correction values are determined based on a piecewise-quadratic correction function in a first direction. The parameters for the piecewise-quadratic correction function in the first direction are calculated based on a plurality of piecewise-quadratic correction functions in a second direction. The correction values may be positional gain adjustment values.

Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, and methods of making and using the foregoing.

Abstract: The present invention relates to binding proteins having tethered light chains and methods of making and using them.

Abstract: A server for providing scheduling services to at least two remote devices includes a communications interface for transmitting scheduling options to the at least two remote devices and receiving user inputs from the at least two remote devices. The server further includes a processing circuit configured to manage scheduling services for the at least two remote devices. In one embodiment, the server provides scheduling services for two users, allowing the two users to schedule an appointment with each other. In another embodiment, the server provides scheduling services for a first user and a plurality of second users, allowing the multiple users to schedule an appointment with one another.

Abstract: Methods, systems and apparatuses are disclosed for approximating vertical and horizontal correction values in a pixel value correction calculation. Multiple vertical and/or horizontal correction curves are used and may be employed for one or more color channels of the imager. The use of multiple correction curves allows for a more accurate approximation of the correction curves for image pixels.

Abstract: The present invention relates to potato virus NIa protease variants or fragments thereof, polynucleotides encoding them, and methods of making and using the foregoing.

Abstract: A foot operable percussion instrument producing jingling sounds similar to a tambourine is useable by a solo performer and possesses a wedge-shaped body with an inclined striking surface for the striking by a foot or a portion thereof. The wedge-shaped body is connected to a base plate member by a pair of rigid connectors that together define a fulcrum so that the front portion of the wedge-shaped block pivots downwardly when struck by a foot on the inclined striking surface and rights itself when the foot is lifted. The jingling sound produced is of short duration.

Abstract: Methods, systems and apparatuses are disclosed for approximating vertical and horizontal correction values in a pixel value correction calculation. Multiple vertical and/or horizontal correction curves are used and may be employed for one or more color channels of the imager. The use of multiple correction curves allows for a more accurate approximation of the correction curves for image pixels.

Abstract: The present invention relates to potato virus NIa protease variants or fragments thereof, polynucleotides encoding them, and methods of making and using the foregoing.

Abstract: The present invention provides a method for the treatment of allergic and inflammatory diseases or conditions by administering a compound of Formula (I). The invention provides a method of treatment that is particularly suited for patients with a high degree of airway eosinophilia in contrast to those with a lower degree of airway eosinophilia. The invention also provides a method of treatment that is particularly suited for patients with a high atopic status in contrast to those patients with a lower atopic status.

Abstract: Methods, apparatuses and systems for storing approximations of multiple spatial pixel value adjustment surfaces for use in pixel value correction. The adjustment surfaces may be used for positional gain adjustment. A representation of the multiple adjustment surfaces is stored as coefficients representing a multi-dimensional solid of two-dimensional adjustment surfaces. The stored coefficients are used to determine a plurality of additional sets of coefficients which sets are then in turn used to determine pixel correction values of adjustment surfaces.