Abstract: Systems and methods for targeted advertising to specific consumers are disclosed. A system may include a memory storing instructions; and at least one processor configured to execute the instructions to: receive, over a network, consumer data from a client device; identify a plurality of client-provided consumers from the consumer data; obtain a plurality of unique consumer identifiers corresponding to the plurality of client-provided consumers; and identify at least one first overlapping unique consumer identifier by matching at least one of the plurality of client-provided consumers with at least one publisher-provided consumer provided by a first publisher device of a plurality of publisher devices, the first publisher device having a highest priority among the plurality of publisher devices.

Abstract: The present disclosure provides filter materials adapted for use as a filter element in an aerosol delivery device and methods of forming such filter materials suitable for use as a filter element in such devices. The disclosure provides, in some embodiments, a filter material which includes a plurality of fibers selected from the group consisting of regenerated cellulose, hemp, sisal, esparto, kenaf, jute, flax, wood, reconstituted tobacco, and combinations thereof, wherein the filter material is in the form of a nonwoven sheet or a fibrous tow.

Abstract: The present disclosure provides methods of treating breast cancer including administering aqueous suspensions com-prising solubilized fulvestrant, non-solubilized fulvestrant particles having one or more of an LD Dv(1 0) between about 1.5 and about 2.1 microns, an LD Dv(50) between about 5.5 and about 9.0 microns, and an LD Dv(90) between about 15 and about 35 microns, with the aqueous suspensions further including a surfactant, a polyvinylpyrrolidone, and a sugar alcohol, and a water-soluble excipient. The water-soluble excipient can be an aryl-Ci-6alk-OH, a Ci-6alkyl-OH, a buffering salt, a polysorbate, a polyalkylene glycol, a Ci-i2alkylene glycol, a phosphatidylcholine, or a combination thereof.

Abstract: A high pressure engine propulsion system, such as a rocket engine, having improved engine performance is described herein. A liquid propellant, such as liquid oxygen, is paramagnetic. Cavitation bubbles of the liquid propellant can form in an inducer tunnel of a turbopump when the pressure in the turbopump inlet drops below the vapor pressure of the liquid propellant. The turbopump includes a magnetic field source external to the inducer tunnel to generate or provide a steady magnetic field across or through the inducer tunnel. The steady magnetic field interacts with the paramagnetic propellant, thereby reducing or eliminating cavitation bubble growth, causing cavitation bubbles to collapse, retaining cavitation bubbles within the inducer tunnel, the like, or combinations thereof.

Abstract: The present disclosure provides compounds with increased metabolic stability for inhibiting a virus infection, such as a Baltimore Group IV RNA virus infection, such as rhinovirus, coxsackievirus, norovirus and coronavirus. Aspects of the present disclosure also include methods of treating the virus infection in a subject with compounds with increased metabolic stability.

Abstract: Systems and methods for targeted advertising to specific consumers are disclosed. A system may include a memory storing instructions; and at least one processor configured to execute the instructions to: receive, over a network, consumer data from a client device; identify a plurality of client-provided consumers from the consumer data; obtain a plurality of unique consumer identifiers corresponding to the plurality of client-provided consumers; and identify at least one first overlapping unique consumer identifier by matching at least one of the plurality of client-provided consumers with at least one publisher-provided consumer provided by a first publisher device of a plurality of publisher devices, the first publisher device having a highest priority among the plurality of publisher devices.

Abstract: The present disclosure provides compounds and methods for inhibiting a virus infection, such as a Baltimore Group IV RNA virus infection. Aspects of the present disclosure also include methods of treating a Baltimore Group IV RNA virus infection in a subject. The present disclosure also provides pharmaceutical compositions related to the same.

Abstract: A system and method for locating a medical device within a body uses wireless technology to transmit the information obtained from the sensors to a mobile device or other computing system. A software application on the mobile device or computing system can be used to display the information, wherein the user can control the display without needing to contact any items that are not sterile.

Abstract: The present disclosure provides methods of treating breast cancer including administering aqueous suspensions comprising solubilized fulvestrant, non-solubilized fulvestrant particles having one or more of an LD Dv(10) between about 1.5 and about 2.1 microns, an LD Dv(50) between about 5.5 and about 9.0 microns, and an LD Dv(90) between about 15 and about 35 microns, with the aqueous suspensions further including a surfactant, a polyvinylpyrrolidone, and a sugar alcohol, and a water-soluble excipient. The water-soluble excipient can be an aryl-Ci-6alk-OH, a Ci-6alkyl-OH, a buffering salt, a polysorbate, a polyalkylene glycol, a Ci-i2alkylene glycol, a phosphatidylcholine, or a combination thereof.

Abstract: An oral product in the form of an edible film is provided herein. The edible film can include a binder in an amount of at least about 30 percent by weight; a plasticizer in an amount of at least about 5 percent by weight; and an active agent, wherein the edible film is orally dissolvable. The edible film can also be used as a component of another oral product, e.g., a fleece-based pouched product. The edible film can form a coating on a portion of an interior or exterior surface of a fleece-based pouched product.

Abstract: Devices, systems, methods and computer program products are disclosed that facilitate part layer curing by an additive manufacturing device wherein each element of the part layer is exposed to light from a light source until the element receives sufficient energy to cure. In an aspect, received energy is calculated based on both the light received directly from the light source and light received from surrounding elements due to dispersion and other effects. The present disclosure enables consistent curing across a part layer, facilitate the creation of sharp outer structures, and allow fragile structures to be built alongside larger structures without a loss of quality, clarity, or resolution.

Abstract: Playback, recording, and analysis of music scales via software configuration. In an embodiment, a graphical user interface is generated with staff and keyboard canvases, visually representing a music staff and keyboard, respectively, a scale input, parameter input(s), and a play input. In response to selection of a scale, the staff canvas is updated to visually represent the notes in the scale. In response to the selection of a musical parameter, the staff canvas and/or keyboard canvas are updated to reflect the musical parameter. In response to selection of the play input, a soundtrack of the scale is output, while simultaneously highlighting the note, being played, on the staff canvas and the key, associated with the note being played, on the keyboard canvas.

Abstract: A pouched product adapted for release of a water-soluble component therefrom is provided herein. The pouched product can include an outer water-permeable pouch defining a cavity; and a composition adapted for oral use situated within the cavity and comprising a water-soluble component; wherein the outer water-permeable pouch comprises a nonwoven web comprising a biodegradable binder, the biodegradable binder comprising one or more aliphatic polyesters.

Abstract: A self-sealing membrane sleeve assembly including a sleeve member having a tubular body extending between first and second ends. At least one shield assembly extends about at least a portion of the circumference of the sleeve member from the first end to the second end. The at least one shield assembly made from a generally rigid, fire resistant material. A first sealing membrane assembly is secured to the first end of the tubular body and a second sealing membrane assembly is secured to the second end of the tubular body.

Abstract: A method is disclosed to calibrate factors to correct at least one hardware deviation in an image system of an additive manufacturing device where the method includes sampling output positions in a grid pattern created by the additive manufacturing device to establish at least one sample point based on loop vertices, measuring the grid pattern with a measurement and inspection system, producing a data file which contains positions of the sampled points with corrected locations as determined with the measurement and inspection system, applying the corrected locations to each respective profile loop vertices by adjusting coordinates of each loop vertex based on the correction factors and performing a validation print to verify that the additive manufacturing device is calibrated correctly based on the corrected locations. A system and a non-transitory processor readable storage medium residing on a mobile device, providing an executable computer program product are also disclosed.

Abstract: A method is disclosed where the method includes gathering loop data from a datafile representing a cross section of an object to additively manufacture with an additive manufacturing device, evaluating the loop data to apply at least one correction factor to the loop data based on at least one of information about the material being used to additively manufacture the object and an identified imaging hardware error within the additive manufacturing device, creating a first raster image of the loop data based on the at least one correction factor applied to the loop data with the additive manufacturing device and additively manufacturing a part of the object based on the first raster image. A system and a non-transitory processor readable storage medium residing on a mobile device, providing an executable computer program product are also disclosed.

Abstract: The present disclosure provides compounds and methods for inhibiting a virus infection, such as a Baltimore Group IV RNA virus infection, such as rhinovirus, coxsackievirus, norovirus and coronavirus. Aspects of the present disclosure also include methods of treating a virus infection in a subject.