Abstract: A replenishing device in an additive manufacturing system is disclosed having a sweeper that extends to a base of a reservoir that holds a liquid resin and horizontally across at least a portion of a cure inhibiting layer located on the base of the reservoir that functions as an imaging plate, with the sweeper positioned across at least a portion of a side of the cure inhibiting layer to at least one of retard a flow of the liquid resin across a portion of a top surface of the cure inhibiting layer by providing a physical barrier to the liquid resin, remove debris from the cure inhibiting layer, and agitate the liquid resin. Other devices are also disclosed.

Abstract: An impact sensing system includes a first impact sensor having a flexible dielectric layer, a first printed electrode on a first side of the layer, and a second printed electrode on a second side of the layer. The second printed electrode overlies and is moveable toward and away from the first electrode by deformation of the flexible dielectric layer. Further, the layer maintains a capacitance between to the first electrode and the second electrode that changes with a movement of the second electrode toward or away from the first electrode. The system further includes a first readout circuit electronically coupled with the first and second electrodes to measure a change in the capacitance and output a corresponding voltage.

Abstract: The present disclosure provides peptides that modulate an immune response in an individual. The present disclosure provides peptides that modulate cellular responses in vitro. The present disclosure provides compositions comprising the peptides. The peptides and compositions are useful in methods of modulating an immune response in an individual, which methods are also provided.

Abstract: A system and method for locating a medical device within a body uses wireless technology to transmit the information obtained from the sensors to a mobile device or other computing system. A software application on the mobile device or computing system can be used to display the information, wherein the user can control the display without needing to contact any items that are not sterile.

Abstract: The present invention provides non-naturally occurring polypeptides that specifically bind hepatitis B virus (HBV) DNA; and polynucleotides encoding the polypeptides. The present invention further provides methods of detecting HBV DNA; methods of detecting a covalently closed circular DNA (cccDNA) form of HBV; and methods for treating HBV infection.

Abstract: The present disclosure provides methods and compositions relating to in vitro cultures of human hepatocyte cell lines which exhibit a primary human hepatocyte phenotype. Such cell lines are susceptible to infection by a hepatotrophic virus, such as HCV or HBV, and support both viral replication and high levels of viral particle production. Such in vitro cultures find use in production and study of hepatotrophic virus, as well as methods of screening (e.g., for antiviral drugs, assessing drug metabolism), and study of primary human hepatocytes.

Abstract: Devices, systems, methods and computer program products are disclosed that facilitate part layer curing by an additive manufacturing device wherein each element of the part layer is exposed to light from a light source until the element receives sufficient energy to cure. In an aspect, received energy is calculated based on both the light received directly from the light source and light received from surrounding elements due to dispersion and other effects. The present disclosure enables consistent curing across a part layer, facilitate the creation of sharp outer structures, and allow fragile structures to be built alongside larger structures without a loss of quality, clarity, or resolution.

Abstract: Systems, methods and computer program products are disclosed that facilitate measuring the light output of an additive manufacturing device light source without utilizing additional equipment, such as a light meter. Once the light source output has been measured, such information can be utilized for a variety of purposes, including, but not limited to: (i) delivering a uniform amount of light energy over time to each portion of a layer being formed; (ii) adjusting the intensity of each controllable element (e.g., pixel) of the light source to the measured minimum, thereby creating a uniformly intense light source; and (iii) minimizing the build time of layers or portions of a layer being formed based on the maximum intensity available within a given area of the build area.

Abstract: A gap services router (GSR) that is a drop-in replacement of an end of life Cisco™ 2811 integrated services router (ISR). The GSR is a routing, switching, and computing platform that provides a technology refresh in the same form factor as the legacy 2811 router. The GSR is one rack unit in size and comprises the latest routing and switching technology from Cisco™, preferably a Cisco™ 5915 embedded services router (ESR) and a Cisco™ embedded services 2020 switch. The GSR contains two WAN ports and twenty-five LAN ports, with power over ethernet capability on all ports. The GSR also optionally includes an embedded server module capable of running the latest virtualization technology. An embedded server module in the GSR includes a removable solid state drive (SSD) that is zeroed upon removal. The GSR is preferably used to replace 2811 ISRs integrated in deployed military equipment.

Abstract: The present invention provides non-naturally occurring polypeptides that specifically bind hepatitis B virus (HBV) DNA; and polynucleotides encoding the polypeptides. The present invention further provides methods of detecting HBV DNA; methods of detecting a covalently closed circular DNA (cccDNA) form of HBV; and methods for treating HBV infection.

Abstract: A system for users to communicate with other users through music clips is provided. A clip management module receives from a user a selection of a music clip, which is a segment of a musical piece that conveys the emotion or thought of the user. A communication module receives from the user at least one recipient and transmits the selected music clip to the recipient. The recipient can respond by sending a music clip to the user thereby creating a musical conversation.

Abstract: The present invention provides non-naturally occurring polypeptides that specifically bind hepatitis B virus (HBV) DNA; and polynucleotides encoding the polypeptides. The present invention further provides methods of detecting HBV DNA; methods of detecting a covalently closed circular DNA (cccDNA) form of HBV; and methods for treating HBV infection.

Abstract: Devices, methods, and computer program products for facilitating the assembly of three-dimensional parts in a layer-wise fashion are disclosed, wherein separation forces between the assembler device and the parts are minimized at certain interfaces. Parts may be produced from polymers, photopolymers, metals, or other materials. In some aspects of the present disclosure, separation forces are minimized via the utilization of a cure inhibiting layer on a top surface of the image plate and via sliding the part from contact with a portion of the image plate having high elevation to above a portion of the image plate with low elevation. In some aspects, the assembler device further comprises a sweeper configured to expose the cure inhibiting layer to a source of cure inhibitor after a cure cycle.

Abstract: This invention relates to emulsion compositions that can warm on contact with ambient moisture and can be used as lubricants on the skin of a person. They may be formulated in the form of a lotion and maintain stability for a significant period of time.

Abstract: This invention proposes a new way of sealing the working chambers in Wankel-type rotary engines, by using ferrofluids and magnets in place of typical metal seals. The use of ferrofluids will allow for not only a better seal, but one that is easier to maintain.

Abstract: A device for the treatment of hyperhydrosis by application of electric current to a treatment area of the skin is described. The device comprises: a) a garment comprising a first electrode adapted for contacting said treatment area; b) a second electrode adapted for contacting the treatment area or skin proximal to the treatment area; and c) a power delivery unit in electrical communication with said first and second electrodes. The power delivery unit provides a customized dose of electricity to the treatment area. In one embodiment, the garment is a glove.

Abstract: The present invention provides non-naturally occurring polypeptides that specifically bind hepatitis B virus (HBV) DNA; and polynucleotides encoding the polypeptides. The present invention further provides methods of detecting HBV DNA; methods of detecting a covalently closed circular DNA (cccDNA) form of HBV; and methods for treating HBV infection.

Abstract: A device for the treatment of hyperhydrosis by application of electric current to a treatment area of the skin is described. The device comprises: a) a garment comprising a first electrode adapted for contacting said treatment area; b) a second electrode adapted for contacting the treatment area or skin proximal to the treatment area; and c) a power delivery unit in electrical communication with said first and second electrodes. The power delivery unit provides a customized dose of electricity to the treatment area. In one embodiment, the garment is a glove.