Abstract: The use of gaseous oxygen for the production of a therapeutic gas for inhalation by a patient who has been identified as a person with a mitochondrial disorder or a coenzyme Q10 deficiency, for the treatment of mitochondrial disorders or Q10 deficiencies is disclosed. For the first time a non-invasive method is disclosed, upon what the body's own level of Q10 can be raised significantly without further interventions.

Abstract: A hydraulic power unit for a slip control system of a vehicle hydraulic brake system includes a hydraulic block that is equipped with hydraulic constructional elements such as hydraulic pumps and solenoid valves of the slip control system and an electric motor that is configured to drive the hydraulic pumps. The power unit further includes hydraulic accumulators attached on the outside on the hydraulic block in a control unit housing arranged next to an electronic control unit of the slip control system in order to save installation space.

Abstract: A hydraulic unit for a slip controller of a hydraulic vehicle brake system includes an electric motor, a plurality of hydraulic pumps, a hydraulic block, a plurality of solenoid valves, a rotation angle sensor, an electronic control unit, and a valve cover. The electric motor is positioned on a narrow side of the hydraulic block, and is configured to drive the hydraulic pumps. The electronic control unit includes a contacting mechanism, and is positioned in the valve cover. The electric motor and the solenoid valves are arranged so that the electric motor and electromagnets of the solenoid valves protrude to approximately a same extent from the hydraulic block to enable simple commutation with the rotation angle sensor and the contacting mechanism of the electronic control unit.

Abstract: The present disclosure provides a build plate for physically adhering or holding a three-dimensional (3D) object to a build surface and methods for mechanically anchoring the 3D object to the build surface using printing or building materials. In one embodiment, a build plate comprises a plurality of anchor holes spaced throughout a top surface of the first build plate, in which an individual anchor hole comprises a top hole portion and a bottom chamfer hole portion that is larger in size than the top portion.

Abstract: A diagnostic tool for an agricultural field irrigation system that has a control panel including at least depressible operating switches for controlling the operation of the system includes a wireless transmitter, a wireless receiver and an actuator. The wireless transmitter is configured to selectively encode and transmit an encoded signal, and the wireless receiver is configured to receive and decode the encoded signal, and provide an output signal to activate the actuator. The actuator is operatively connected to the wireless receiver, and is configured to be removably secured to the control panel. The actuator activates at least one of the system operating switches in response to receipt of the output signal from the receiver.

Abstract: A motor vehicle 10 includes a hydromechanical powersplit transmission 11 having a hydraulic pump motor unit drive shaft 44 and a gear 76. The shaft 44 and gear 76 are drivingly connected together with a spline connection 160. The spline connection 160 includes an internal spline connector 161 and an external spline connector 162. Each spline connector 161, 162 includes a spline portion 166, 174 and a generally smooth portion 168, 175 adjacent its spline portion. During assembly, generally smooth portion 168 of the internal spline connector 160 engages and guides spline portion 174 of the external spline connector 162 to longitudinally and circumferentially align the spline portions 174 and 166. After assembly, the spline portions 166, 174 and the generally smooth portions 168 and 175 are radially aligned with and engage one another to form a rigid driving connection.

Abstract: The use of gaseous oxygen for the production of a therapeutic gas for inhalation by a patient who has been identified as a person with a mitochondrial disorder or a coenzyme Q10 deficiency, for the treatment of mitochondrial disorders or Q10 deficiencies is disclosed. For the first time a non-invasive method is disclosed, upon what the body's own level of Q10 can be raised significantly without further interventions.

Abstract: Heat pumps and refrigerating machines operate optimally if the temperature difference of the connected heat sources and heat sinks is as small. If this is not the case, there are two negative effects: At a high spread, increased dissipation occurs in the condensers and evaporators. In order to increase spread, the heat return flow is frequently mixed with the heat pump flow. For this purpose, hydraulic separators and overflow valves are employed. This results in highly dissipative mixing of heat carrier medium with differing temperatures. Using a pair of intermediate storage means, the dissipation that occurs can be drastically reduced. The low spread of the heat pump is adjusted to the high spread of the remaining system. The COP of the system is substantially improved. With heat pumps, the improvement ranges from about 5% to 20%.

Abstract: The present invention refers to pharmaceutical composition comprising a DPP-IV inhibitor.

Abstract: The invention relates to a piston steam engine having flash vaporization. Said inventive piston steam engine can be operated with various working mediums and at different temperatures. The liquid working medium is successively injected into individual prechambers of the vapor machine cylinder. The inlet temperature of said working medium is adapted to the expansion step in the working cycle of the machine in relation to the respective point in time of injection.

Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.

Abstract: The present invention relates to compounds of formula (I) wherein R1 to R4 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.

Abstract: The present invention relates to a valve device (13) for controlling a gas flow in a fresh air system (6) of an internal combustion engine (2), in particular of a motor vehicle, with a housing (17) which encloses at least one duct section (19) through which the gas flow (14) can pass transversely to the main flow direction (18), with at least one flap (15) which can be rotated about an axis of rotation (21) which runs transversely with respect to the main flow direction (18) in the duct section (19). In order to improve the fail-safety of the valve device (13), at least one rotary frame (24) is provided, which can be rotated about an axis of rotation (25) which runs transversely with respect to the main flow direction (18) in the duct section (19) and has a frame opening (26) through which the gas flow (14) can pass.

Abstract: The present invention relates to compounds of the formula (I) wherein R1 and R2 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, non-insulin dependent diabetes mellitus and/or impaired glucose tolerance, obesity, and/or metabolic syndrome or ?-cell protection.

Abstract: The present invention relates to compounds of the formula (I) wherein R1 and R2 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, non-insulin dependent diabetes mellitus and/or impaired glucose tolerance, obesity, and/or metabolic syndrome or ?-cell protection.

Abstract: A diagnostic tool for an agricultural field irrigation system that has a control panel including at least depressible operating switches for controlling the operation of the system includes a wireless transmitter, a wireless receiver and an actuator. The wireless transmitter is configured to selectively encode and transmit an encoded signal, and the wireless receiver is configured to receive and decode the encoded signal, and provide an output signal to activate the actuator. The actuator is operatively connected to the wireless receiver, and is configured to be removably secured to the control panel. The actuator activates at least one of the system operating switches in response to receipt of the output signal from the receiver.

Abstract: The invention relates to a piston steam engine having flash vapourisation. Said inventive piston steam engine can be operated with various working mediums and at different temperatures. The liquid working medium is successively injected into individual prechambers of the vapour machine cylinder.

Abstract: The present invention relates to compounds of formula (I) wherein R1 is as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.

Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.

Abstract: The present invention provides compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.