Abstract: Compositions are provided including a free-radically reactive component, a photoradical generator, and either a crosslinker having a photodegradable linkage or a chemical blowing agent, an epoxy component, and a photoacid generator. Polymeric films including reaction products of the compositions are also provided. A debondable article including a polymeric film containing a crosslinker having a photodegradable linkage is further provided, as well as a method of debonding the article. Foam compositions are also provided, including foamed matrices including the reaction products of the compositions. Further, articles and foam adhesives are provided including a substrate and a composition or foam composition disposed on the substrate.

Abstract: A system for providing emergency assistance includes receiving audio, visual, or text data about an ongoing emergency at a public safety answering point, comparing that data to a database of other emergencies with an artificial intelligence engine, recognizing patterns in aggregated and correlated data by the artificial intelligence engine, and generating appropriate audio, visual, and text output for a human operator to respond to the emergency. An AI engine receives audio data, visual data, and text data related to ongoing emergencies being received at public safety answering points and compares it with data from other emergencies. The AI engine identifies key words and patterns and generates appropriate messages for operators. The system continuously generates feedback to the AI engine to aid in machine learning. The feedback includes: “message was correct; continue drawing this conclusion”; and “message was wrong; do not continue drawing this conclusion.

Abstract: The present invention relates generally to the photovoltaic generation of electrical energy. The present invention relates more particularly to photovoltaic arrays for use in photovoltaically generating electrical energy. Aspects of the present invention provide a variety of photovoltaic roofing elements and systems that include, for example, interlocking geometries to provide for water handling and integration with conventional roofing materials; and wire management features that can protect wiring and associated electrical components from physical and/or environmental damage.

Abstract: A method for maximizing a battery life and a temperature monitoring device are provided. The method includes detecting whether a low temperature mode is set in the temperature monitoring device; when the low temperature mode is detected, implementing a plurality of measures to enhance the battery life of the temperature monitoring device. The temperature monitoring device includes a memory, a button coupled with a light emitting diode unit, a battery and a processor. The temperature monitoring device is able to implement the method for maximizing life of the battery.

Abstract: The present invention relates generally to porphyrin derivatives and their use in detecting poly- and perfluoroalkyl substances (PFAS). In particular, the present invention is directed to porphyrin derivatives having at least one receptor arm comprising an anion binding group substituted with a poly- or perfluorinated aliphatic group and their use as sensors for the detection of PFAS.

Abstract: A finger-mounted device may include finger-mounted units. The finger-mounted units may each have a body that serves as a support structure for components such as force sensors, accelerometers, and other sensors and for haptic output devices. The body may have sidewall portions coupled by a portion that rests adjacent to a user's fingernail. The body may be formed from deformable material such as metal or may be formed from adjustable structures such as sliding body portions that are coupled to each other using magnetic attraction, springs, or other structures. The body of each finger-mounted unit may have a U-shaped cross-sectional profile that leaves the finger pad of each finger exposed when the body is coupled to a fingertip of a user's finger. Control circuitry may gather finger press input, lateral finger movement input, and finger tap input using the sensors and may provide haptic output using the haptic output device.

Abstract: The ?2-adrenergic receptor (?2AR) is a primary target in the treatment of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). Since ?-agonist treatment of airway disease can have severe side effects, compounds that attenuate the side effects of ?-agonists have been identified via their ability to inhibit ?2AR interaction with ?-arrestins. These compounds are specific for the ?2AR and effectively protect against the desensitization observed with ?-agonist treatment in model cells and airway tissue. The present disclosure provides compounds and methods for treating airway disease, such as but not limited to COPD and/or asthma.

Abstract: System for use in directing an article sorting operation includes a routing engine, first and second vehicles, and a grid comprising a plurality of grid cells, each grid cell having a grid cell length X. First size vehicle has a first vehicle length greater than the grid cell length X and second size vehicle has a second vehicle length greater than the first vehicle length. The system is configured to: receive article information of first and second articles; assign the first article to be transported by the first size vehicle, and the second article to be transported by the second size vehicle; determine a first route for the first size vehicle such that the first route has a first width equaling A*X, and a second route for the second size vehicle such that the second route has a second width equaling B*X.

Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

Abstract: The present invention is related to processes for preparing ruxolitinib, or a salt thereof, and related synthetic intermediates related thereto.

Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.

Abstract: A system includes a wearable sensor device including an accelerometer configured to be worn by a person and to record sensor data during an activity performed by the person; an analysis element configured to receive the sensor data from the wearable sensor, determine sensor orientation data of the wearable sensor during the activity based on the sensor data, translate the sensor orientation data of the wearable sensor to person orientation data of the person during the activity, determine, for the person during the activity, (a) lift rate, (b) maximum sagittal flexion, (c) average twist velocity, (d) maximum moment, and (e) maximum lateral velocity, and determine a score representative of an injury risk to the person during the activity based on such data; and a tangible feedback element configured to provide at least one tangible feedback based on the score so as to reduce the injury risk.

Abstract: An accessory attachment system includes a base plate that provides a plate attachment interface and at least one accessory including an accessory attachment interface to connect to the plate attachment interface. In one example, the accessory attachment interface comprises at least one mounting foot that has a predefined shape to pull the at least one accessory against a side wall mounted base plate as the foot is inserted into an aperture in the base plate and moved vertically to a mounted position. In one example, a locking mechanism that is separate from the mounting foot is movable between a locked position where the accessory is prevented from being removed from the base plate and an unlocked position where the at least one accessory is allowed to be removed from the base plate.

Abstract: A portable, single-fixation, magnetic derailment mitigation device may be fixed on a rail track for measuring the deflection of the rail track. The magnetically fixing device is used for measuring vertical track deflection (sleeper voids), horizontal track deflection, ambient and rail temperature, rail angle, vibration, displacement, and location. The derailment mitigation device sends digital notifications and/or alarms during the live train and/or freight operations to help prevent derailments, rail buckles, breaks, and pull apart. The measured data and/or all events obtained from the derailment mitigation device is stored in the data storage such as cloud storage and viewed from any smart devices.

Abstract: A method can comprise forming a component comprising a first mating surface; coupling the component to an airfoil having a second mating surface and a Field Assisted Sintering Technology (“FAST”) system; heating, via the FAST system, the airfoil and the component; and applying, via the FAST system, a mechanical pressure between the first mating surface and the second mating surface to join the airfoil to the component and form a blade, the component at least partially defining a leading edge of the blade in response to joining the airfoil to the component

Abstract: A tool for installing a resiliently-compressible building component adjacent the end of one or panels which may be incorporated into a system including a substrate. The tool has two arms, in a location where the tool moves from a tool first position to a tool second position at a positioning body rate which is not greater than a rate of expansion of the resiliently-compressible building component. A set of arms be attached to a plurality of adjustable adjacent spaced-apart armatures for multiple points of contact. The tool second position width is at least 105% of the tool first position width and is not more than 150% of the tool first position width.

Abstract: A catheter pump system is disclosed. The catheter pump system can include a shaft assembly and an impeller coupled with a distal portion of the shaft assembly. The catheter pump system can include a motor assembly, the motor assembly comprising a chamber and a shaft-driving portion disposed in the chamber. The shaft-driving portion can be configured to impart rotation to the impeller through the shaft assembly. The chamber can be filled with a gas that at least partially surrounds the shaft-driving portion. A fluid pathway can convey fluid proximally during operation of the catheter pump system. A bypass pathway can be in fluid communication with the fluid pathway, the bypass pathway configured to direct at least a portion of the fluid to bypass the chamber.

Abstract: A utility vehicle is configured for off-road terrain and may include a plurality of mounting members configured to support a load and/or support the vehicle during transport. The utility vehicle also includes an upper frame assembly which is movable between a first position and second position. The upper frame assembly may be moved to the second position during transportation of the utility vehicle. Further, the utility vehicle includes a plurality of configurations for a rear cargo area, thereby allowing for passengers or cargo to be supported.

Abstract: This disclosure provides peptides which can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.

Abstract: Devices, methods and graphical user interfaces for manipulating user interfaces based on fingerprint sensor inputs are provided. While a display of an electronic device with a fingerprint sensor displays a first user interface, the device may detect movement of a fingerprint on the fingerprint sensor. In accordance with a determination that the movement of the fingerprint is in a first direction, the device allows navigating through the first user interface, and in accordance with a determination that the movement of the fingerprint is in a second direction different from the first direction, the device allows displaying a second user interface different from the first user interface on the display.