Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

Abstract: A fluid connection for a vehicle includes a container selectively coupled with a compartment of the vehicle. The container includes at least one passage in fluid communication with an interior of the container. At least one port is disposed on the compartment and in fluid communication with a climate control system in the vehicle. The at least one passage is in fluid communication with the at least one port when the container is coupled with the compartment. The at least one port has an elongated cross-sectional area at a connection interface between the at least one port and the at least one passage.

Abstract: A laser level including a control mechanism housing which houses a control mechanism, the control mechanism including at least a top surface and a bottom surface. A protective structure extends from the control mechanism housing configured to protect the control mechanism from impact and including an upper structure which extends from a top surface of the control mechanism housing and a lower structure which extends from a bottom surface of the control mechanism housing.

Abstract: A surgical system includes a surgical instrument, a motion sensor, and a computing device. The surgical instrument includes a housing, an end effector assembly distally-spaced from the housing, and a movable component movable relative to the housing. The motion sensor is disposed on or within the housing and configured to sense a vibration signature associated with movement of the movable component relative to the housing. The computing device communicates with the motion sensor, is configured to receive the vibration signature therefrom, and is configured to determine a condition of the movable component based on the vibration signature. A method of monitoring a surgical instrument includes sensing a vibration signature generated from movement of a movable component of a surgical instrument relative to a housing of the surgical instrument, and determining, based on the sensed vibration signature, a condition of the movable component.

Abstract: A coupling assembly for a vehicle includes a container selectively coupled with a compartment of the vehicle. The container includes at least one first port in fluid communication with an interior of the container. At least one second port is disposed on a wall of the compartment and is in fluid communication with a climate control system in the vehicle. A connection assembly is between the container and the wall. The connection assembly includes a positioning feature configured to align the at least one first port with the at least one second port. The connection assembly further includes a securing feature configured to bias the container toward the wall when the container is coupled with the wall to maintain fluid communication between the interior and the climate control system.

Abstract: A communication protocol translation system includes a non-self-describing protocol (NSDP) sensor device configured to receive electrical signals from at least one sensor, generate NSDP sensor data according to a NSDP based on the received electrical signals; a multi-function medical device configured to receive and process self-describing protocol (SDP) data formatted according to an SDP; and an SDP translating device interposed between and in communication with the NSDP sensor device and the multi-function medical device, wherein the SDP translating device is configured to receive the NSDP sensor data, generate the SDP data based on the NSDP sensor data and an NSDP-to-SDP conversion algorithm, enrich the SDP data with additional information, and transmit the enriched SDP data to the multi-function medical device.

Abstract: A system for haptic stimulation includes a haptic device and preferably interfaces with and/or includes a virtual platform. A method for haptic stimulation includes: receiving a set of inputs; determining one or more parameters associated with a virtual object based on the set of inputs; and prescribing a stimulation pattern to one or more haptic actuators of a haptic device. Additionally or alternatively, the method 200 can include any or all of: presenting information to a user; selecting one or more haptic actuators of a haptic device based on the parameter(s); and/or any other suitable processes performed in any order.

Abstract: A protective display case configured to encase memorabilia is provided. The protective display case includes a front chassis assembly having a front chassis and a front chassis glazing member. A gasket is seated in a groove formed in the front chassis. A spacer is seated over the front chassis glazing member. Memorabilia is positioned within a cutout formed in the spacer. A rear chassis assembly has a rear chassis and a rear chassis glazing member. The rear chassis assembly is attached to the front chassis assembly with the gasket, spacer and memorabilia positioned therebetween. A bezel is configured to cover perimeters of the front and rear chassis assemblies, gasket, spacer and memorabilia. Front and rear layers of protective glass are secured to the front and rear chassis assemblies.

Abstract: A fire-fighting system includes a pump, a nozzle for directing fluid flow from the pump to a target area, a discharge valve controlling fluid flow between the pump and the nozzle, a sensor coupled to the nozzle, and a controller communicatively coupled to the sensor. The sensor detects movement of the nozzle and generates a signal indicative of the detected movement. The controller communicatively coupled is configured to receive the signal from the sensor, and control at least one of the discharge valve, the pump, and the nozzle based on the detected movement of the nozzle.

Abstract: A tracheal tube (e.g., an endotracheal tube) includes an inserting cannula (that may be able to swivel), and wherein the inserting cannula is connected to an elbow adaptor through a Bayonet Neill-Concelman (BNC) connection. The BNC connection may provide more secure connection of the corresponding components and may be able to withstand greater amounts of force exerted on them without becoming detached from each other. The elbow adapter may further be coupled to a pressure release valve that will alleviate pressure buildup within the tracheal tube.

Abstract: Disclosed are prodrug compounds that can be converted to mesembrine under biologically relevant conditions, such as hydrolysis in vivo; and related methods of preparing and using these compounds. Stable preparations of isolated mesembrine stereoisomers are also provided.

Abstract: The present disclosure is directed to ion-exchange systems and devices that can monitor key parameters related to the performance of the ion-exchange device. Specifically, the ion-exchange systems and devices disclosed herein can provide real time voltage drop across groups of membrane pairs using diagnostic spacer borders between the pairs. In addition, the ion-exchange systems and devices disclosed herein can monitor the compression force applied by the compression plates holding the ion-exchange systems and devices together.

Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.

Abstract: A processor may include an instruction pipeline that executes program instructions in-order according to a program order. During operation, the instruction pipeline may detect that data is missing for a first instruction. In response, the instruction pipeline may send a request to load the missing data for the first instruction. However, the instruction pipeline may not necessarily stall operation to wait for the missing data to be loaded. Instead, the instruction pipeline may continue executing instructions subsequent to the first instruction. During the continued execution, the instruction pipeline may detect that data is missing for a second instruction, and send a request to load the missing data for the second instruction. The instruction pipeline may continue such operation until it determines that a condition occurs that prevents the continued execution. When the condition occurs, the instruction pipeline may stop the continued execution, and then re-execute the first instruction.

Abstract: Multilayer optical film comprising at least a plurality of alternating first and second optical layers. Embodiments of the multilayer optical film are useful, for example, in UV-C shield, UV-C light collimator, and UV-C light concentrator applications.

Abstract: A system and method for enhanced speed thermal printing has a drive roller for contacting thermochromic medal to a thermal printhead. The drive roller includes a cam which causes the drive roller to decelerate as it approaches the printhead such that contact with the thermal printhead and the thermochromic media is at a highest force point. The drive roller accelerates as it is pulled back from the printhead prior to a next printing cycle.

Abstract: A surge control system includes a rotor system with at least one compressor section and at least one turbine section operably coupled to a shaft. The surge control system also includes sensors configured to collect sensor data from the rotor system, an electric motor operably coupled to the rotor system, and a controller. The controller is operable to detect surge event from the sensor data, determine an amount of power to apply to the rotor system, and increase the amount of power provided to the rotor system to recover from the surge event.

Abstract: The invention features a headset, and systems including the headset, equipped with electrical sensors. The headset is suitable for use by a child and suitable for use in a gaming system, e.g., to train attention.

Abstract: Methods of evaluating mixing are disclosed relating to the preparation and mixing of materials. Materials prepared may transition from heterogeneous mixtures to homogenous mixtures while the current of a motor is monitored. Quantities relating to the rate of change of power or the rate of change of entropy may be calculated in evaluating the sufficiency of mixing. Methods of evaluating lubricant degradation are also disclosed.