Abstract: Medical devices such as catheters can include structure or provision that permit a physician or other health care professional to adjust the stiffness of at least a portion of the medical device. In some instances, the medical device may be adjusted prior to inserting the medical device into a patient. In some cases, the medical device may be adjusted while in use within the patient.

Abstract: Medical devices such as catheters can include structure or provision that permit a physician or other health care professional to adjust the stiffness of at least a portion of the medical device. In some instances, the medical device may be adjusted prior to inserting the medical device into a patient. In some cases, the medical device may be adjusted while in use within the patient.

Abstract: A medical implant includes a metallic base, a tie layer, and at least a first layer overlying an outer surface of the tie layer. The tie layer is bonded to at least a portion of a surface of the metallic base. The tie layer includes magnesium or a magnesium-based alloy. The tie layer can have an outer surface comprising dendritic grains. The tie layer can have a rough outer surface defined by pores, projecting grain structures, and/or projecting particles. A method of producing a tie layer on a medical device includes applying magnesium or a magnesium-based alloy to the medical device and cooling the magnesium or the magnesium-based alloy to produce a rough outer surface.

Abstract: A delivery system has a stent and a balloon. The stent has a first section made of a plurality of interconnected framework members which define a plurality of potential side branches. The balloon is a dual lumen balloon that can inflate from the proximal end to the distal end with a plurality of protrusions and/or herniations.

Abstract: Described herein are implantable medical devices for delivering a therapeutic agent to the body tissue of a patient, and methods for making such medical devices. In particular, the implantable medical devices, such as intravascular stents, have a coating which includes at least one coating composition and has an exposed abluminal surface and an exposed luminal surface or exposed side surface.

Abstract: Among other things, a bio-erodible implantable endoprosthesis comprises a member that includes (a) a core having a surface, and (b) a bio-erodible metal on a least a portion of the surface of the core, wherein the bio-erodible metal erodes more slowly than the core and includes openings through which physiological fluids can access the core upon implantation.

Abstract: Medical devices such as catheters can include structure or provision that permit a physician or other health care professional to adjust the stiffness of at least a portion of the medical device. In some instances, the medical device may be adjusted prior to inserting the medical device into a patient. In some cases, the medical device may be adjusted while in use within the patient.

Abstract: A stent may comprise a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut. A serpentine band may comprise alternating straight struts and s-shaped struts. Connector struts may comprise first connector struts and second connector struts, wherein the first connector struts are nonparallel to the second connector struts.

Abstract: In at least one embodiment, a stent comprises an expandable framework comprising a plurality of serpentine bands and a plurality of connector struts. Each serpentine band comprises a plurality of alternating struts and turns. A plurality of the serpentine bands each have their proximal turns aligned on a common stent circumference and comprise first distal turns and second distal turns. The first distal turns are aligned with one another on a common stent circumference. The second distal turns aligned with one another on another common stent circumference. Each band in the plurality comprises first struts and second struts. Each first strut is attached between a proximal turn and a first distal turn, and each second strut is attached between a proximal turn and a second distal turn. The second struts are wider than said first struts.

Abstract: In at least one embodiment, a stent includes an unexpanded configuration, a nominally expanded configuration, and a fully expanded configuration. The stent further includes a plurality of circumferential bands and a plurality of connectors connecting adjacent circumferential bands to one another. Each circumferential band has a plurality of struts interconnected by bridges. Adjacent struts form strut pairs and are connected to one another at a first end or a second end but not both. Each strut pair defines an opening between the struts of the strut pair; the bridges extend into the openings. In the unexpanded configuration, the struts are straight along their length. Also in the unexpanded configuration, the bridges include two adjacent straight segments that are connected by a u-shaped segment, and the straight segments are parallel to one another and to the longitudinal axis of the stent.

Abstract: A stent may include a side branch cell comprising a plurality of petals. Each petal may comprise struts and turns, and may have a longitudinal axis oriented at an angle to the stent longitudinal axis. Each petal may comprise a plurality of struts and at least one turn. For each petal, the width of a turn may be greater than the width of the struts. Upon expansion of the stent, a petal may deploy outwardly in a stent radial direction beyond an outer diameter of the rest of the stent.

Abstract: A bifurcated stent that uses telescoping rings to support or form the side branch lumen. This design allows the bifurcation branch to extend easily, to a useful distance, and to be deployed along oblique angles. Best of all, this design avoids the need to deploy a bent stent.

Abstract: A stent has a plurality of expansion columns that extend in a radial direction to form a circumference of the stent and interconnected in the axial direction to form an overall axial length of the stent. Each expansion column has a plurality of first cells and a plurality of second cells that alternates along the expansion column with at least one first cell. Each first cell has at least two facing walls extending in the radial direction that have a first width. The second cells each have at least two facing walls that extend in the radial direction which have a second with greater than the first width. The first cell uses less force to open than the second cell, but upon opening provides increased radial strength by creating a substantially vertical cell wall.

Abstract: A stent assembly comprises a second stent body and a substantially tubular first stent body defining a first lumen and containing a side branch opening. In an undeployed state, the second stent body is at least partially comprised of rings having peaks and valleys at least some of the valleys of adjacent rings being interconnected by bridges. In an expanded state, the rings of the second stent body define a second lumen opening in fluid communication with the first lumen. The second lumen has superior body vessel coverage and is flexible enough to form an oblique angle relative to the longitudinal axis of the first stent body.

Abstract: A stent may include a side branch cell comprising a plurality of petals. Each petal may comprise struts and turns, and may have a longitudinal axis oriented at an angle to the stent longitudinal axis. Each petal may include a plurality of straight struts which are substantially parallel to the stent longitudinal axis. Each petal may include at least one appendage which may be oriented substantially parallel to the stent longitudinal axis, and which may remain substantially parallel to the stent longitudinal axis as the stent is deployed. The dimension of the side branch cell about the circumference of the stent may increase more than the dimension of the side branch cell in a stent lengthwise directions as the stent is expanded.

Abstract: Medical devices such as catheters can include structure or provision that permit a physician or other health care professional to adjust the stiffness of at least a portion of the medical device. In some instances, the medical device may be adjusted prior to inserting the medical device into a patient. In some cases, the medical device may be adjusted while in use within the patient.

Abstract: A stent assembly includes a branch portion and a main body with a proximal main body, a contralateral main body, and a distal main body. The branch portion is in fluid communication with the main body. In the expanded state the branch portion extends at an oblique angle in relation to the longitudinal axis. The main body and the branch portion are at least partially constructed of interconnected struts. A plurality of the struts are connected one to another by a peak. The distal main body has a greater peak width to strut width ratio than does the proximal main body and contralateral main body.

Abstract: A stent has a substantially cylindrical tubular body with at least one expandable side branch that has a plurality of members. The plurality of members includes at least one first member having a first width and at least one second member having a second width, where the first width is greater than the second width. Each of the at least one first members and each of the at least one second members define a cell that has at least two stable cell geometries.

Abstract: Techniques are disclosed that allow a stent to be folded within a balloon of a stent delivery system. In one example, a stent has first and second columns that extend from a proximal end to a distal end along a longitudinal axis. Each of the first columns extend substantially parallel to the longitudinal axis and comprise a plurality of elements that each have a substantially polygonal shape. Each of the second columns extend substantially parallel to the longitudinal axis and are between adjacent first columns. Each of the respective second columns include a plurality of first connectors that have a curvilinear shape and that extend in a substantially circumferential direction to connect adjacent first columns. The stent also has a plurality of second connectors, wherein at least one of the second connectors extends between a first element and a second element.

Abstract: In at least one embodiment, a stent comprises an expandable framework comprising a plurality of serpentine bands and a plurality of connector struts. Each serpentine band comprises a plurality of alternating struts and turns. A plurality of the serpentine bands each have their proximal turns aligned on a common stent circumference and comprise first distal turns and second distal turns. The first distal turns are aligned with one another on a common stent circumference. The second distal turns aligned with one another on another common stent circumference. Each band in the plurality comprises first struts and second struts. Each first strut is attached between a proximal turn and a first distal turn, and each second strut is attached between a proximal turn and a second distal turn. The second struts are wider than said first struts.