Abstract: A stent may comprise a plurality of serpentine bands connected by connector struts. The stent may further comprise a side branch cell having a plurality of outwardly deployable petals. Each serpentine band may have an approximate longitudinal axis. A portion of the serpentine bands may be flared in the unexpanded state, wherein a portion of the axis of each flared band is oriented helically about a portion of the stent. The bands may reorient during stent expansion, whereafter the axis of each band is oriented in a circumferential direction.

Abstract: The invention is directed to a stent that delivers multiple therapeutic regimens from different regions of the stent.

Abstract: In some embodiments, a stent comprises a side branch structure defining an inner side branch cell. The inner side branch cell has a shape that is different from any other cell of the stent. The stent further comprises first and second support members, which are positioned on opposite sides of the side branch structure. The first and second support members each have a strut width that is greater than the width of a strut included in the side branch structure. The stent further comprises first and second connecting members, which are positioned on opposite ends of the side branch structure. Each connecting member is connected at one end to the first support member and is connected at the other end to the second support member. Each connecting member comprises a serpentine structure having a plurality of straight struts and turns. One or both of the connecting members includes at least one straight strut that has a length that is at least ten times its width.

Abstract: An expandable bifurcated stent is formed of a main body and a first branch. The body wall is made up of interconnected stent members that define a plurality of cells, at least one of which is a side opening. The first branch body extends from the body wall from at least two regions adjacent the side opening. At least one stent member adjacent the perimeter is bioabsorbable.

Abstract: A stent may comprise a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut. A serpentine band may comprise alternating straight struts and s-shaped struts. Connector struts may comprise first connector struts and second connector struts, wherein the first connector struts are nonparallel to the second connector struts.

Abstract: A bifurcated stent having a side branch constructed out of a bioabsorbable material. The side branch comprises one or more bio cells which are flexible and easily deformable when the stent is in the unexpanded state. The bio cells have a locking member which fixedly holds the bio cells in place once the stent assumes the expanded state. The locking member uses oppositely directed hooks or ratchet teeth to prevent contraction in the bio cells once the expanded state is assumed. By having an appropriate alternation between flexibility and rigidity the side branch is flexible enough to deal with the geometric difficulties of bending and deploying a side branch while being fixed and rigid enough to properly support and scaffold a side branch assembly. The deployment of the side branch can be facilitated by the use of a ratcheting device. The side branch can also have a flared shape.

Abstract: A bifurcated stent that is positionable adjacent to a branched body vessel. The stent includes a tapered middle portion with a side branch assembly for positioning within the deviating branch of a body vessel. The portion of the stent positioned within the first body vessel and the portion positioned within the main branch vessel have largely different sized diameters. The middle region tapers steeply to bridge this diameter differential. The tapered middle region also angles the side branch assembly which can easily be extended at an angle to the main body of the stent.

Abstract: A stent may comprise a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut. A serpentine band may comprise alternating straight struts and s-shaped struts. Connector struts may comprise first connector struts and second connector struts, wherein the first connector struts are nonparallel to the second connector struts.

Abstract: A bifurcation having a main branch portion and a side branch portion which interface about a frame. The frame is expandable from a first configuration enclosing a first area to a second configuration enclosing a second area wherein the second area is larger than the first area.

Abstract: A stent has a main body, which has a circumference that defines a primary lumen and longitudinal axis, which extends therethrough. A first region of the main body comprises at least one band disposed circumferentially about the longitudinal axis. A second region of the main body comprises a plurality of interconnected rings concentrically disposed about a side branch opening. An outermost ring extends fully about the circumference of the main body. Each of the rings consist of two longitudinally oriented elements and two circumferentially extending elements.

Abstract: In at least one embodiment, a stent comprises a plurality of serpentine bands and a plurality of connector columns. Each serpentine band comprises a plurality of alternating straight band struts and turns. Adjacent serpentine bands are connected across a connector column by a plurality of connector struts. Each connector strut is connected at one end to a turn of one serpentine band and connected at the other end to a turn of another serpentine band. The turns of a serpentine band comprise connected turns that connect to a connector strut and unconnected turns that do not connect to a connector strut. At least one serpentine band comprises a repeating pattern of three band struts and then five band struts extending between connected turns as the serpentine band is traversed. At least one serpentine band comprises a repeating pattern of three band struts and then one band strut extending between connected turns as the serpentine band is traversed.

Abstract: A bifurcated stent that uses turning segments to reduce the strain at regions which bend at extreme angles. The turning segments can be placed on side branch petals or on connectors connecting the petals to the stent body. Combining the turning segments with connectors of different length and tethers provides for a stent with high flexibility that can accommodate various shaped body vessels. This design allows the bifurcation branch to extend easily, to a useful distance, and to be deployed along oblique angles. Best of all, this design avoids the problems of angularly strained side branch.

Abstract: An improved system for screening a multiple of candidate therapeutic or chemotherapeutic agents for efficacy as to a specific patient, in which a tissue sample from the patient is harvested, cultured and separately exposed to a plurality of treatments and/or therapeutic agents for the purpose of objectively identifying the best treatment or agent for the particular patient. Specific method innovations such as tissue sample preparation techniques render this method practically as well as theoretically useful. The identity of the malignant cells in culture is advantageously confirmed using binding reagents/staining systems specific for epithelial cells, since carcinomas are ubiquitously epithelial in nature. Cells of interest and thus confirmed as epithelial/carcinomal may then be assayed for sensitive to an infinite variety of malignancy treating agents including chemotherapeutic agents, radiation, immunotherapy, and so on.