Abstract: A stent having one or more beneficial agents which enhance the healing effect of the stent. The agent is positioned within a reservoir. The reservoir dynamically releases the agent when the stent is expanded. The reservoir makes use of various changes in stent shape during expansion to assure proper release of the agent. Agent release can be modulated at various points along the stent and with various rates of release. The reservoirs can also be cooperatively combined with features that enhance stent flexibility, structural integrity, and which prevent recoil.

Abstract: An expandable stent has a plurality of expandable rings formed of a plurality of struts and at least one first connector interconnecting adjacent expandable rings. The plurality of struts include a first strut and the at least one first connector has a first arm. A first portion of the first arm is engaged to a first portion of the first strut so that the first portion of the first arm and the first portion of the first strut define a through hole.

Abstract: A stent, with expanded and unexpanded configurations, comprises a substantially tubular body having a proximal end region, a distal end region, and defining a first lumen therethrough. The tubular body comprises a plurality of adjacent deployable elements positioned between the proximal end region and distal end region. In the expanded configuration the deployable elements define a second lumen. The first lumen has a first longitudinal axis and the second lumen has a second longitudinal axis which is at an oblique angle relative to the first longitudinal axis. The first lumen is in fluid communication with the second lumen. The tubular body comprises a track region which further comprises at least two struts. The struts are substantially parallel to each other and the first longitudinal axis in the unexpanded configuration. The track region is comprised of at least one of the deployable elements.

Abstract: The invention is directed to a stent that delivers multiple therapeutic regimens from different regions of the stent.

Abstract: Described herein are implantable medical devices for delivering a therapeutic agent to the body tissue of a patient, and methods for making such medical devices. In particular, the implantable medical devices, such as intravascular stents, have a coating which includes at least one coating composition and has an exposed abluminal surface and an exposed luminal surface or exposed side surface.

Abstract: Disclosed herein is a stent having a generally tubular stent body with a first end region, a second end region, and a third region therebetween. The stent has a plurality of circumferential serpentine bands and a plurality of connector columns. Each connector column is located between two immediately adjacent serpentine bands, with each connector column having at least one connector. Connectors are connected at one end to one serpentine band and at the other end to an immediately adjacent serpentine band. The connectors of the first and second end regions have a first length which is substantially parallel to the longitudinal axis, and the connectors of the third region have a length greater than the first length and form an oblique angle relative to the longitudinal axis.

Abstract: An expandable bifurcated stent is formed of a main body and a first branch. The body wall is made up of interconnected stent members that define a plurality of cells, at least one of which is a side opening. The first branch body extends from the body wall from at least two regions adjacent the side opening. At least one stent member adjacent the perimeter is bioabsorbable.

Abstract: A composite stent structure and methods of manufacturing same, include a stent wall having two or more layers of the same or different material. The wall provides various means of drug delivery while maintaining the stent's overall structure. The outer layers and/or inner layers may have holes, reservoirs, or openings that allow for the delivery of drugs or other therapeutic agents.

Abstract: An expandable bifurcated stent is formed of a main body and a first branch. The body wall is made up of interconnected stent members that define a plurality of cells, at least one of which is a side opening. The first branch body extends from the body wall from at least two regions adjacent the side opening. At least one stent member adjacent the perimeter is bioabsorbable.

Abstract: A delivery system has a stent and a balloon The stent has a first section made of a plurality of interconnected framework members which define a plurality of potential side branches. The balloon is a dual lumen balloon that can inflate from the proximal end to the distal end with a plurality of protrusions and/or herniations.

Abstract: A stent may comprise a plurality of serpentine bands connected by connector struts. The stent may further comprise a side branch cell having a plurality of outwardly deployable petals. Each serpentine band may have an approximate longitudinal axis. A portion of the serpentine bands may be flared in the unexpanded state, wherein a portion of the axis of each flared band is oriented helically about a portion of the stent. The bands may reorient during stent expansion, whereafter the axis of each band is oriented in a circumferential direction.

Abstract: A bifurcated stent that is positionable adjacent to a branched body vessel. The stent includes a number of stent members at least some of which have slits extending through them. The slits are positioned relative to the tensile and compressive forces imposed by stent expansion to enhance the flexibility of the stent members. The slits can be positioned to increase stent compression about a catheter, increase how far the stent can be bent during catheter deployment, and allow specific portions of the stent to have improved flexibility. The slits can allow the stent to assume a bent shape, and compensate for rigidity imposed the bifurcating side branch. The slits can be combined with curved sections to create a highly flexibly stent.

Abstract: Described herein are implantable medical devices, such as implantable or intravascular stents, for delivering a therapeutic agent, and methods for making such medical devices. In one embodiment, the medical device comprises a stent having a plurality of struts, at least one of which has a cavity disposed therein. A therapeutic agent is delivered from the cavity through and opening in a strut surface. In another embodiment, the medical device is a stent having a coating disposed on the side surface(s) of at least one strut for deliver of a therapeutic agent from the coating.

Abstract: A stent has a substantially cylindrical tubular body with at least one expandable side branch that has a plurality of members. The plurality of members includes at least one first member having a first width and at least one second member having a second width, where the first width is greater than the second width. Each of the at least one first members and each of the at least one second members define a cell that has at least two stable cell geometries.

Abstract: A stent may comprise a plurality of serpentine bands connected by connector struts. The stent may further comprise a side branch cell having a plurality of outwardly deployable petals. Each serpentine band may have an approximate longitudinal axis. A portion of the serpentine bands may be flared in the unexpanded state, wherein a portion of the axis of each flared band is oriented helically about a portion of the stent. The bands may reorient during stent expansion, whereafter the axis of each band is oriented in a circumferential direction.

Abstract: The invention is directed to a stent that delivers multiple therapeutic regimens from different regions of the stent.

Abstract: In some embodiments, a stent comprises a side branch structure defining an inner side branch cell. The inner side branch cell has a shape that is different from any other cell of the stent. The stent further comprises first and second support members, which are positioned on opposite sides of the side branch structure. The first and second support members each have a strut width that is greater than the width of a strut included in the side branch structure. The stent further comprises first and second connecting members, which are positioned on opposite ends of the side branch structure. Each connecting member is connected at one end to the first support member and is connected at the other end to the second support member. Each connecting member comprises a serpentine structure having a plurality of straight struts and turns. One or both of the connecting members includes at least one straight strut that has a length that is at least ten times its width.

Abstract: An expandable bifurcated stent is formed of a main body and a first branch. The body wall is made up of interconnected stent members that define a plurality of cells, at least one of which is a side opening. The first branch body extends from the body wall from at least two regions adjacent the side opening. At least one stent member adjacent the perimeter is bioabsorbable.

Abstract: A bifurcated stent having a side branch constructed out of a bioabsorbable material. The side branch comprises one or more bio cells which are flexible and easily deformable when the stent is in the unexpanded state. The bio cells have a locking member which fixedly holds the bio cells in place once the stent assumes the expanded state. The locking member uses oppositely directed hooks or ratchet teeth to prevent contraction in the bio cells once the expanded state is assumed. By having an appropriate alternation between flexibility and rigidity the side branch is flexible enough to deal with the geometric difficulties of bending and deploying a side branch while being fixed and rigid enough to properly support and scaffold a side branch assembly. The deployment of the side branch can be facilitated by the use of a ratcheting device. The side branch can also have a flared shape.

Abstract: A stent may comprise a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut. A serpentine band may comprise alternating straight struts and s-shaped struts. Connector struts may comprise first connector struts and second connector struts, wherein the first connector struts are nonparallel to the second connector struts.