Abstract: A purified guayule natural rubber is provided which has a particular Mw, Mn, Mw/Mn, resin content and ash content. Also provided are related processes for obtaining the purified guayule natural rubber from an initial co-solvent based miscella which contains solubilized guayule rubber, at least one polar solvent and at least one non-polar solvent using a fractionation system.

Abstract: A system for managing a plurality of medical devices includes a stream processor for receiving medical data from a plurality of medical devices and for generating metadata and storing the medical data and the metadata for each of the devices. The system further includes data storage for storing the medical data and the metadata. The system further includes a communications interface for implementing at least one communications protocol for providing access to the medical data and the metadata. The system further includes an application for accessing the medical data and the metadata via the communications interface and generating, based on the medical data and the metadata, output indicative of operating status of the medical devices.

Abstract: Disclosed herein is a salt, a crystalline anhydrous form, a hydrate, a solvate, or a co-crystal of a free base compound 2-(6-azaspiro[2.5]octan-6-yl)-N-[2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl]-4-[(2-hydroxyethanesulfonyl)amino]benzamide (Compound A); method of preparation, pharmaceutical compositions, and method of treating a disease mediated by a motor protein kinesin family member 18A (KIF18A) inhibition, wherein said disease is a neoplastic disease, including a cancer or a tumor.

Abstract: A carriage arrangement has a driving bar arrangement and a carriage. The carriage has a roller part with a plurality of running rollers. The roller part is displaceable transversely to the longitudinal extent of the carriage with respect to a wing part which can be mounted immovably on a wing. A driving bar of the driving bar arrangement has a control projection which engages in a control slot which is formed obliquely to the longitudinal extent of the carriage. To guide the roller part on the wing part is provided a first roller bearing guide which extends transversely to the longitudinal extent of the carriage. The first roller bearing guide has rolling bodies which are supported both on the wing and roller part so forces acting in the direction of the longitudinal extent of the carriage are channelled away from the wing part into the roller part with low friction.

Abstract: An organic light-emitting diode (OLED) display may have an array of organic light-emitting diode pixels that each have OLED layers interposed between a cathode and an anode. Voltage may be applied to the anode of each pixel to control the magnitude of emitted light. The conductivity of the OLED layers may allow leakage current to pass between neighboring anodes in the display. To reduce leakage current and the accompanying cross-talk in a display, the pixel definition layer may disrupt continuity of the OLED layers. The pixel definition layer may have an undercut to disrupt continuity of some but not all of the OLED layers. The undercut may be defined by three discrete portions of the pixel definition layer. The undercut may result in a void that is interposed between different portions of the OLED layers to break a leakage path formed by the OLED layers.

Abstract: Methods and systems for optimizing user interaction with a software application. One system includes an electronic processor configured to receive a collection of interaction data including a plurality of interaction sequences and data associated with each of the plurality of interaction sequences, determine a performance metric for each of the plurality of interaction sequences, and train, with the collection of interaction data and the performance metric determined for each of the plurality of interaction sequences, an artificial intelligence (“AI”) model using supervised learning. The electronic processor is also configured to receive a current interaction sequence of a user for the software application and generate, via the AI model as applied to the interaction pattern of the user, a recommendation, for display within a user interface, for a modified user interaction pattern of the user for the software application.

Abstract: An example folding device (100) includes a hinge assembly (106), a first assembly (102), and a second assembly (104). The hinge assembly (106) defines a first axis (108) and a second axis (110). The first assembly (102) includes a first arm (112), formed from a first material and rotatably connected to the hinge assembly about the first axis, a first main housing component (114), and a first divider (116) disposed between the first arm (112) and the first main housing component (114). The first main housing component (114) is formed from a second material that is different than the first material. The second assembly (104) includes a second arm (118), formed from the first material and rotatably connected to the hinge assembly about the second axis, a second main housing component (120), and a second divider (122) disposed between the second arm (118) and the second main housing component (120). The second main housing component (120) is formed from a second material that is different than the first material.

Abstract: A stage hoist motor assembly includes a first electric motor including a first brake and a second electric motor including a second brake. The first electric motor and the second electric motor are stacked one atop the other within a common plane. A cable winch is rotatable about a winch axis and includes a cable winch shaft that is driven by the first and second electric motors through respective ones of a first drive coupling and a second drive coupling. A width of the motors is less than a width of the winch. Moreover, the motors are stacked one atop the other within a common plane to provide a compact foot print that is favorable to use in performance venue environments.

Abstract: An apparatus configured to transmit and receive a radio frequency (RF) signal is provided. The apparatus includes a digital-to-analog converter (DAC) configured to convert a digital signal into an analog signal, a power amplifier configured to amplify the analog signal, and an antenna configured to output, as the RF signal, the amplified analog signal to the outside. The DAC includes a current cell matrix including a plurality of current cells configured to generate the analog signal, a plurality of normal paths configured to control the plurality of current cells to be turned on or off, based on the digital signal, and a plurality of alternative paths configured to selectively consume power, based on a pattern of the digital signal.

Abstract: Several heart wall remodeling devices and methods are disclosed. One heart wall remodeling device includes an anchoring portion having an elongated anchor body with a distal anchor end portion and a proximal anchor end portion opposite the distal anchor end portion, a rotation joint portion having a distal joint end portion fixedly attached to the proximal anchor end portion and a proximal joint end portion opposite the distal joint end portion and a hemostasis element having a distal hemostasis end portion detachably connected to the proximal joint end portion. One heart wall remodeling device includes a tensioner that applies a variable tension between anchors.

Abstract: The present disclosure provides a system and methods for time of flight imaging, comprising: (a) an imaging sensor configured to receive a plurality of light signals reflected from a surgical scene, wherein the imaging module comprises a first imaging unit configured for time of flight (TOF) imaging; a second imaging unit configured for at least one of laser speckle imaging and fluorescence imaging; and an optical element configured to (i) direct a first set of light signals to the first imaging unit and (ii) direct a second set of light signals to the second imaging unit; and (b) an image processing module operatively coupled to the first imaging unit and the second imaging unit, wherein the image processing module is configured to generate one or more images of the surgical scene based on the first set of light signals and the second set of light signals.

Abstract: Methods and systems provide for predicting and constraining kinematic trajectories of an object within an environment. In one embodiment, the system obtains sensor data from one or more sensor data streams; predicts, via an inertial tracking model, a trajectory of an object in an environment in a continuous fashion using the sensor data; retrieves environmental data consisting of a number of environmental constraints relating to the environment; generating, via a reinforcement learning (RL) agent, a number of corrections to the trajectory of the object based on the environmental constraints within the environmental data; and provides real-time tracking and navigation of the object in the environment based on the continuously predicted trajectory and the corrections to the predicted trajectory.

Abstract: A firearm safety mechanism assembly is provided. The firearm safety mechanism assembly includes a firearm with a receiver, a trigger guard coupled to the firearm, and a housing pin. The firearm safety mechanism assembly includes a trigger safety mechanism. The trigger safety mechanism includes a plate, a rod extending from the plate, a trigger coupled to the rod, and a lever nested within the trigger. The lever includes a lever first end and a lever second end, where the lever rotates between a first position and a second position. In the first position, the lever first end abuts a housing pin.

Abstract: Systems, devices and methods for implanting neuromodulation systems and, in some cases, spinal fixation systems using a single surgical incision and placing the system components with direct visual and physical access through an open access. Implantable pulse generators of the neuromodulation systems include lead receptacles and, in some cases, the leads may bifurcate into two leads at a proximal side of the leads. Anchors are provided that are capable of anchoring a body of a neuromodulation lead to the rod of a spinal fixation system and/or engaging bone.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure may be performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure may be performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: Detection of mechanical coupling slippage in rotary encoder systems is provided where position data samples are obtained from a rotary encoder coupled to rotating element and angular acceleration data is determined based on the position data samples. At least two acceleration peaks are detected in the angular acceleration data, including at least one negative acceleration peak and at least one positive acceleration peak. Slippage occurrence of the mechanical coupling are detected when an interval between a negative acceleration peak and a positive acceleration peak of the at least two acceleration peaks is less than a first time period. If at least a threshold number of slippage occurrences are detected within a second time period, a mechanical coupling error signal is generated.