Abstract: A database processing system performs a first database access call accessing a first construct representing a differential component amount between a normal and different state. This identifies a plurality of components and, for each, a corresponding first association between (a) a change in amount of the respective component in a first plurality of first component datasets and a second plurality of second component datasets and (b) a change in state between the normal and different state. A second database access call accesses a second construct representing a measure of differential component amount between a native and exposed sample. The second construct identifies all or a portion of the plurality of components and, for each, a corresponding second association between a change of amount of the respective component between a third and fourth plurality of component datasets. The first associations and corresponding second associations determine whether the entity affects the transition.

Abstract: The present invention relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein Ring A, Ring B, R1—R16, n and p are defined herein. The novel nitrogen-linked benzisoxazole sulfonamide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in patients. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth, such as cancer, in patients.

Abstract: A database processing system performs a first database access call accessing a first construct representing a differential component amount between a normal and different state. This identifies a plurality of components and, for each, a corresponding first association between (a) a change in amount of the respective component in a first plurality of first component datasets and a second plurality of second component datasets and (b) a change in state between the normal and different state. A second database access call accesses a second construct representing a measure of differential component amount between a native and exposed sample. The second construct identifies all or a portion of the plurality of components and, for each, a corresponding second association between a change of amount of the respective component between a third and fourth plurality of component datasets. The first associations and corresponding second associations determine whether the entity affects the transition.

Abstract: A multi-processor device is disclosed. The multi-processor device includes interface circuitry to receive requests from at least one host device. A primary processor is coupled to the interface circuitry to process the requests in the absence of a failure event associated with the primary processor. A secondary processor processes operations on behalf of the primary processor and selectively receives the requests from the interface circuitry based on detection of the failure event associated with the primary processor.

Abstract: A method of converting a CMYK Standard Color Printer to a CMYW Converted White Printer, comprising the steps: providing a CMYK Standard Color Printer; wherein a CMYK Standard Color Printer comprises: a black toner cartridge; wherein the black toner cartridge is installed in toner cartridge slot one; removing the black toner cartridge from the CMYK Standard Color Printer, such that the toner cartridge slot one is empty toner cartridge slot one; providing a white toner cartridge; wherein the white toner cartridge is configured to fit into the empty toner cartridge slot one; installing the white toner cartridge into the empty toner cartridge slot one; and providing raster image processor (RIP) software, such that the CMYK Standard Color Printer is configured to incorporate the white toner into one or more images printed by the CMYK Standard Color Printer in a single pass such that a CMYW Converted White Printer is created.

Abstract: The problem of attaching a donor nerve stump to a recipient nerve for an end-to-side coaptation is solved by the use of a tissue connector. The tissue connector can have a body for receiving the donor nerve stump and one or more overflaps for attaching the tissue connector with the donor nerve stump therein to the epineurium on the side of the recipient nerve. Sutures can also be used to secure the tissue connector and nerves in place.

Abstract: A control component implements pipelined data processing operations in either of two timing domains bridged by a domain-crossing circuit according to one or more configuration signals that indicate relative clock frequencies of the two domain and/or otherwise indicate which of the two timing domains will complete the data processing operations with lowest latency.

Abstract: An interconnected stack of one or more Dynamic Random Access Memory (DRAM) die also has one or more custom logic, controller, or processor die. The custom die(s) of the stack include direct channel interfaces that allow direct access to memory regions on one or more DRAMs in the stack. The direct channels are time-division multiplexed such that each DRAM die is associated with a time slot on a direct channel. The custom die configures a first DRAM die to read a block of data and transmit it via the direct channel using a time slot that is assigned to a second DRAM die. The custom die also configures the second memory device to receive the first block of data in its assigned time slot and write the block of data.

Abstract: Provided herein is a film and methods of producing the same. The film includes a substrate and a layer adjacent to the substrate, wherein a surface of the layer comprises spaced apart protrusions. The methods include providing a substrate, depositing a layer on at least a portion of the substrate, decomposing the layer to form at least a first phase of material and a second phase of material, and removing at least a portion of the second phase from the decomposed layer to form a structured layer.

Abstract: Disclosed is a dynamic random access memory that has columns, data rows, tag rows and comparators. Each comparator compares address bits and tag information bits from the tag rows to determine a cache hit and generate address bits to access data information in the DRAM as a multiway set associative cache.

Abstract: A method of forming a component by material extrusion includes the steps of forming a plurality of first filaments extending along at least a first axis of a three dimensional space and forming a plurality of second filaments crossing the plurality of first filaments by extending in a direction with at least a component along second and third axes in the three dimensional space.

Abstract: A system includes a top drive including a handling ring assembly including a main body, a main shaft that traverses the main body of the handling ring assembly. an internal blowout preventer (IBOP) valve, wherein the main shaft engages the IBOP valve. a two-piece actuator sleeve assembly including a non-rotating portion and a rotating portion, at least one hydraulic cylinder connected to the main body of the handling ring assembly, wherein the at least one hydraulic cylinder actuates the two-piece actuator sleeve assembly, and left and right hand crank assemblies having left and right wireless encoders connected thereto, wherein the crank assemblies with the wireless encoders are attached to, and are configured to rotate with, the IBOP valve along with the rotating portion of the two-piece actuator sleeve assembly.

Abstract: A method of forming a component utilizing material extrusion includes the steps of (1) delivering a hopper of particulate media formed of a primary material into an extruder, (2) selectively providing an infill material into the primary material within the extruder, (3) delivering a filament of the primary material and the infill material downstream to a nozzle where it is then deposited to form the component, and (4) a control associated with the nozzle selectively delivering the infill material into the primary material, or blocking a delivery of the infill material into the primary material dependent on an area in the component which is being formed.

Abstract: An acoustic treatment for use in an acoustic treatment for a gas turbine engine includes a sheath having a plurality of perforations. A plurality of cell structures extends from the sheath such that the sheath and the cell structures are a monolithic component. The plurality of perforations of the sheath are formed by filaments of a first material that define a first dimension of the perforations having a linear edge and filaments of a second material crossing the filaments of the first material that define a second dimension of the perforations having a linear edge. Such perforations have a non-cylindrical shape defined by the linear edges of the filaments of the first material and the filaments of the second material. A gas turbine engine is also disclosed.

Abstract: A method for interconnecting components of a hydraulic fracturing system using flexible hose or pipe. The flexible hose or pipe can form a singular flow line which interconnects, for example, a pump and a manifold of the hydraulic fracturing system. Each end of the flexible hose or pipe can be tethered (using a safety restraint) to another component of the hydraulic fracturing system. In the event of a rupture or other failure, the safety restraint retains the tethered flexible pipes or hoses in a fixed position to prevent injury to personnel or damage to surrounding equipment.

Abstract: A dynamic random access memory (DRAM) device includes functions configured to aid with operating the DRAM device as part of data caching functions. The DRAM is configured to respond to at least two types of commands. A first type of command (cache data access command) seeks to access a cache line of data, if present in the DRAM cache. A second type of command (cache probe command) seeks to determine whether a cache line of data is present, but is not requesting the data be returned in response. In response to these types of access commands, the DRAM device is configured to receive cache tag query values and to compare stored cache tag values with the cache tag query values. A hit/miss (HM) interface/bus may indicate the result of the cache tag compare and stored cache line status bits to a controller.

Abstract: A device, system, process, and method for extracting metals from contaminated fluid comprising a pretreatment stage, a biosorption column, a thermal dewatering processes, and at least one chemical precipitation step. The biosorption process typically involves at least one fixed bed column wherein metals are reversibly adsorbed to immobilized biomass and eluted with a caustic solution. Treated effluent is further processed via thermal dewatering and chemical precipitation. The process can be used to simultaneously purify industrial wastewater for reuse while extracting valuable metals.

Abstract: A multi-processor device is disclosed. The multi-processor device includes interface circuitry to receive requests from at least one host device. A primary processor is coupled to the interface circuitry to process the requests in the absence of a failure event associated with the primary processor. A secondary processor processes operations on behalf of the primary processor and selectively receives the requests from the interface circuitry based on detection of the failure event associated with the primary processor.

Abstract: Data and error correction information may involve accessing multiple data channels (e.g., 8) and one error detection and correction channel concurrently. This technique requires a total of N+1 row requests for each access, where N is the number of data channels (e.g., 8 data row accesses and 1 error detection and correction row access equals 9 row accesses.) A single (or at least less than N) data channel row may be accessed concurrently with a single error detection and correction row. This reduces the number of row requests to two (2)—one for the data and one for the error detection and correction information. Because, row requests consume power, reducing the number of row requests is more power efficient.

Abstract: A memory system includes two or more memory controllers capable of accessing the same dynamic, random-access memory (DRAM), one controller having access to the DRAM or a subset of the DRAM at a time. Different subsets of the DRAM are supported with different refresh-control circuitry, including respective refresh-address counters. Whichever controller has access to a given subset of the DRAM issues refresh requests to the corresponding refresh-address counter. Counters are synchronized before control of a given subset of the DRAM is transferred between controllers to avoid a loss of stored data.