Abstract: A laser scanning microscope comprises at least one selectively switchable micro-mirror arrangement (DMD) in the illumination beam path and/or detection beam path which is used for the wavelength selection of dispersively divided illumination and/or object light such as reflection, fluorescence.

Abstract: The invention provides novel condensed N-pyrazinyl-sulphonamides of formula (I) and their use in the treatment of chemokine mediated diseases.

Abstract: An offset lithographic printing press combined with a gapped or seamed cylindrical offset printing blanket having pre-made blanket material mounted on a cylindrical sleeve is disclosed, wherein conventional, manufactured blanket material in flat form is adhered to a cylindrical sleeve to economically produce a cylindrical sleeved blanket. The leading and trailing ends of the flat blanket material are joined in close proximity such that a small gap is formed. A seam may be made with a filler material that fills the remaining gap resulting in a seamed sleeved blanket. In use, the blanket's printing surface, which excludes the gap or seam, is aligned with the printing plate's image-bearing surface. Consequently, no loss of print length results from the gap or seam.

Abstract: The invention provides compounds of general formula (I) in which m, A, R1 and Ar have the meanings defined in the specification; a process for, and intermediates used in, their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.

Abstract: The present invention is a controlled expansion projectile (20) having a bonded rear core and includes a metal jacket (22), a dense core (24), and a tip (26). Metal jacket (22) includes a nose portion (28), a middle portion (30), and a heel portion (32). Nose portion (28) includes a front cavity (34) and heel portion (32) includes a rear cavity (36) defined by sidewalls (40), an open end (42), and heel (44). Dense core (24) is typically formed from lead but may be formed from lead compounds or other heavy metals. Dense core (24) may be enclosed in rear cavity (36) using a closure disc (48) joined with heel (44) to seal open end (42). Dense core (24) is joined with sidewalls (40) thereby forming a bond (52). Bond (52) may be a metallurgical bond (54), a mechanical bond (56), or an adhesive bond (58). Tip (26) is at least partially inserted in front cavity (34). Sidewalls (40) of rear cavity (36) are softened during either a metallurgical bonding process or other processes.

Abstract: A shellcase body for use as part of an ammunition cartridge, which includes a base portion at one end, a middle portion having a substantially straight sidewall and joined with the base portion, and a shoulder portion joined to and extending from the middle portion. A neck portion may be joined to and extend from the shoulder portion. The shoulder portion is typically annularly shaped and includes a semi-circular sidewall that extends between an aft end and a fore end. The semi-circular sidewall has a curvature that is defined by a circular arc having a predetermined radius and a center that is positioned a distance away from the shellcase body center longitudinal axis. The shoulder portion is joined with the straight sidewall at a secant point of the circular arc, i.e., the straight sidewall defines a secant line that intersects the circular arc at the aforementioned secant point.

Abstract: The invention provides N-pyrazinyl-phenyl-sulphonamides of formula (I) for use in the treatment of chemokine mediated diseases. Particularly inflammatory diseases, such as asthma.

Abstract: An offset lithographic printing press combined with a gapped or seamed cylindrical offset printing blanket having pre-made blanket material mounted on a cylindrical sleeve is disclosed, wherein conventional, manufactured blanket material in flat form is adhered to a cylindrical sleeve to economically produce a cylindrical sleeved blanket. The leading and trailing ends of the flat blanket material are joined in close proximity such that a small gap is formed. A seam may be made with a filler material that fills the remaining gap resulting in a seamed sleeved blanket. In use, the seam is aligned with the non-print area on the adjacent printing plate, or the adjacent plate cylinder gap of the printing press. Being narrower than the plate cylinder gap, no loss of print length results from the seam.

Abstract: A gapped or seamed cylindrical offset printing blanket having pre-made blanket material mounted on a cylindrical sleeve, and a method for making same, are disclosed, wherein conventional, manufactured blanket material in flat form made by methods known in the art is adhered to a cylindrical sleeve to economically produce a blanket. The leading and trailing ends of the flat blanket material are joined in close proximity such that a small gap is formed. A seam may be made with a filler material that fills the remaining gap resulting in a seamed sleeved blanket In use, the seam is aligned with non-print area on the adjacent printing plate, or the adjacent plate cylinder gap of the printing press.

Abstract: A bracket is disclosed for use in open bottom type cabinets, such as file cabinets, which enables caster assemblies and the like to be secured thereto. The bracket is configured to be secured in the corners of an open bottom cabinet. In accordance with the present invention, the bracket provides stiffening of the cabinet as well as a secure surface for securing caster assemblies thereto. The brackets are simply mounted to the corners of the cabinet utilizing, for example, a pair of fasteners.

Abstract: The invention provides compounds of formula, in which m, A, R?1 and Ar have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.

Abstract: The invention provides N-pyrazinyl-thienylsulphonamides of formula (I) for use in the treatment of chemokine mediated diseases. Particularly inflammatory diseases, such as asthma.

Abstract: A laser scanning microscope comprises at least one selectively switchable micro-mirror arrangement (DMD) in the illumination beam path and/or detection beam path which is used for the wavelength selection of dispersively divided illumination and/or object light such as reflection, fluorescence.

Abstract: The invention provides compounds of general formula (I) in which m, A, R1 and Ar have the meanings defined in the specification; a process for, and intermediates used in, their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.

Abstract: A microscope, especially a laser scanning microscope, with illumination over one wavelength and/or a plurality of wavelengths, wherein a controlling of the intensity of at least one wavelength is carried out by at least one rotatable interference filter which is arranged in the illumination beam path, wherein the at least one wavelength is at least partially reflected out of the illumination beam path and a plurality of filters for different wavelengths can be arranged one behind the other in the illumination beam path.

Abstract: A laser scanning microscope comprises at least one selectively switchable micro-mirror arrangement (DMD) in the illumination beam path and/or detection beam path which is used for the wavelength selection of dispersively divided illumination and/or object light such as reflection, fluorescence.

Abstract: A microscope, especially a laser scanning microscope, with illumination over one wavelength and/or a plurality of wavelengths, wherein a controlling of the intensity of at least one wavelength is carried out by at least one rotatable interference filter which is arranged in the illumination beam path, wherein the at least one wavelength is at least partially reflected out of the illumination beam path and a plurality of filters for different wavelengths can be arranged one behind the other in the illumination beam path.

Abstract: A microscope, especially a laser scanning microscope, with illumination over one wavelength and/or a plurality of wavelengths, wherein a controlling of the intensity of at least one wavelength is carried out by at least one rotatable interference filter which is arranged in the illumination beam path, wherein the at least one wavelength is at least partially reflected out of the illumination beam path and a plurality of filters for different wavelengths can be arranged one behind the other in the illumination beam path.

Abstract: A system (10) for controlling use of or access to a second system, such as a telephone or other communication device, based upon an identifying biological characteristic of a user. The system comprises the telephone (12), including a keypad (14); a display (18); a biometric input device (20); and a controller (24). The controller (22) includes a compact single board computer (24) with an embedded operating system, such as a microkernel version of the Linux operating system, requiring approximately eight megabytes of memory. A person desiring to use the telephone (12) presents the biological characteristic, such as a fingerprint, to the biometric input device (20). A biometric template is created and compared to a resident template database of authorization information. Using a “one-to-many” search engine, requiring approximately 1 megabyte of memory, the present invention is able to perform a linear search of 500 templates within 1.5 seconds or less.

Abstract: The invention relates to novel pyridyl derivatives, their use as medicaments, pharmaceutical formulations containing them and methods for their preparation.