Abstract: The current application is directed to a method for treating pulmonary arterial hypertension (PAH), comprising: providing isolated endothelial progenitor cells (EPCs); treating the EPCs with prostacyclin, wherein the treated EPCs exhibit a hyperproliferative phenotype with enhanced angiogenic property; and administering a composition comprising the treated EPCs into a subject suffering from PAH.

Abstract: A point-of-sale system is a dual-screen stand assembly that includes a merchant terminal and a consumer terminal. The merchant terminal and the consumer terminal can be mated together in a fixed position to form a single unitary stand, or can be separated from each other in a separated position with each terminal serving as its own separate stand. The merchant terminal supports a merchant computing device and is oriented in a merchant-facing direction. The consumer terminal is detachably mated to the merchant terminal and supports a consumer computing device that is oriented in a consumer-facing direction. The point-of-sale system also includes a card reader as part of the customer terminal to perform a payment. The card reader is configured to accepting swipe cards, chip cards or contactless (EMV or NFC) payments.

Abstract: A point-of-sale system is a dual-screen stand assembly that includes a merchant terminal and a consumer terminal. The merchant terminal and the consumer terminal can be mated together in a fixed position to form a single unitary stand, or can be separated from each other in a separated position with each terminal serving as its own separate stand. The merchant terminal supports a merchant computing device and is oriented in a merchant-facing direction. The consumer terminal is detachably mated to the merchant terminal and supports a consumer computing device that is oriented in a consumer-facing direction. The point-of-sale system also includes a card reader as part of the customer terminal to perform a payment. The card reader is configured to accepting swipe cards, chip cards or contactless (EMV or NFC) payments.

Abstract: A graspable handle which incorporates a force indicator with attachment to secure said device to provide resistance for purposes of exercise.

Abstract: Provided are methods for treating or preventing vasculopathy in a subject in need thereof, comprising administering to the subject a prostacyclin and a mesenchymal stem cell (MSC) or a MSC-conditioned culture medium or administering to the subject a MSC or a MSC-conditioned culture medium that has treated with prostacyclin. Pharmaceutical compositions suitable for such treatments are also provided.

Abstract: A substrate includes a first area in which a laser array chip is disposed. The substrate includes a second area in which a planar lightwave circuit is disposed. The second area is elevated relative to the first area. A trench is formed in the substrate between the first area and the second area. The substrate includes a third area in which an optical fiber alignment device is disposed. The third area is located next to and at a lower elevation than the second area within the substrate. The planar lightwave circuit has optical inputs facing toward and aligned with respective optical outputs of the laser array chip. The planar lightwave circuit has optical outputs facing toward the third area. The optical fiber alignment device is configured to receive optical fibers such that optical cores of the optical fibers respectively align with the optical outputs of the planar lightwave circuit.

Abstract: The current application is directed to a method for treating pulmonary arterial hypertension (PAH), comprising: providing isolated endothelial progenitor cells (EPCs); treating the EPCs with prostacyclin, wherein the treated EPCs exhibit a hyperproliferative phenotype with enhanced angiogenic property; and administering a composition comprising the treated EPCs into a subject suffering from PAH.

Abstract: Provided are methods for treating or preventing vasculopathy in a subject in need thereof, comprising administering to the subject a prostacyclin and a mesenchymal stem cell (MSC) or a MSC-conditioned culture medium or administering to the subject a MSC or a MSC-conditioned culture medium that has treated with prostacyclin. Pharmaceutical compositions suitable for such treatments are also provided.

Abstract: The disclosed technology includes a tank system including a gravity tank configured to contain water at atmospheric pressure, a rigid pressurized tank positioned within the gravity tank and configured to contain water at a pressure greater than atmospheric pressure, and a piston assembly positioned below the rigid pressurized tank and configured to open and close the rigid pressurized tank. The gravity tank is configured to channel water at atmospheric pressure into a toilet bowl at a first velocity and the rigid pressurized tank is configured to channel water at the pressure greater than atmospheric pressure into the toilet bowl at a second velocity. The second velocity is greater than the first velocity.

Abstract: An object detection system includes a first camera having a first field of view and a second camera having a second field of view that overlaps with the first field of view. The object detection system includes object detection logic configured to receive a first image from the first camera and a second image from the second camera and identify an object in both the first and second image. The object detection system further includes object mapping logic configured to identify a location of the object based on the first and second image. The object detection system also includes display logic configured to display the location of the object.

Abstract: A flow tube is axially moveable within an actuator body between a first axial position and a second axial position for actuating a downhole tool, such as for closing a subsurface safety valve. The flow tube includes an interior flow bore for conveying fluids from the tubing string through the actuator body. An external flow tube profile defined on the flow tube includes an upper shoulder for engagement with a wiper in the first axial position, a lower shoulder for engagement with the wiper in the second axial position, and a clearance path between the upper and lower shoulders for allowing viscous flow past the wiper when the flow tube is moved between the first and second axial positions.

Abstract: A remotely operated abrasive blasting apparatus is provided. Systems incorporating the apparatus, and methods of treating surfaces using the apparatus and systems are also provided. The abrasive blasting apparatus eliminates the need for human operators to be present in the area being treated, and allows areas inaccessible to human operators to be treated.

Abstract: The application is directed to a method for treating or preventing vasculopathy comprising administrating to a subject in need thereof a pharmaceutical composition comprising mesenchymal precursor cells (MPCs) and a prostacyclin. Also provided a method for treating or preventing vasculopathy in a subject in need thereof, comprising administering to the subject a prostacyclin and a mesenchymal stem cell (MSC) or a MSC-conditioned culture medium or administering to the subject a MSC or a MSC-conditioned culture medium that has treated with prostacyclin. Pharmaceutical compositions suitable for such treatments are also provided.

Abstract: The present invention describes novel methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of ischemic lesions, such as digital ulcers, in subjects with scleroderma (including systemic sclerosis), Buerger's disease, Raynaud's disease, Raynaud's phenomenon and/or other conditions that cause such lesions. The invention also relates to kits for treatment and/or prevention of ischemic lesions, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.

Abstract: Systems and apparatus are provided for monitoring and/or collecting data regarding environmental conditions and optionally personal health information, and generating warnings for a wearer based on acceptable limits for hazards. Using the collected data, the systems and apparatus communicate recommendations to the wearer to improve or maintain personal safety in the detected environment. Methods for monitoring environmental risks and generating warnings based on acceptable limits for hazards are also provided.

Abstract: Methods, systems, and apparatus, including medium-encoded computer program products, for computer aided design of physical structures using data format conversion (e.g., of output(s) from generative design processes) and user interface techniques that facilitate the production of 3D models of physical structures that are readily usable with 2.5-axis subtractive manufacturing, include: modifying smooth curves, which have been fit to contours representing discrete height layers of an object, to facilitate the 2.5-axis subtractive manufacturing; preparing an editable model of the object using a parametric feature history, which includes a sketch feature, to combine extruded versions of the smooth curves to form a 3D model of the object in a boundary representation format; reshaping a subset of the smooth curves responsive to user input with respect to the sketch feature; and replaying the parametric feature history to reconstruct the 3D model of the object, as changed by the user input.

Abstract: A device for heating and quenching a tubular member has a central axis. The device includes a first quenching ring, a second quenching ring axially spaced from the first quenching ring, and a heating ring axially positioned between the first quenching ring and the second quenching ring. Each quenching ring and the heating ring is configured to receive the tubular member. The heating ring is fixably coupled to the first quenching ring and the second quenching ring. The heating ring includes an induction coil configured to heat an annular target zone along the tubular member. The first quenching ring is configured to deliver a first quenching fluid to the target zone and a first annular heat affected zone along the tubular member, and the second quenching ring is configured to deliver a second quenching fluid to the target zone and a second annular heat affected zone along the tubular member.

Abstract: A flow tube is axially moveable within an actuator body between a first axial position and a second axial position for actuating a downhole tool, such as for closing a subsurface safety valve. The flow tube includes an interior flow bore for conveying fluids from the tubing string through the actuator body. An external flow tube profile defined on the flow tube includes an upper shoulder for engagement with a wiper in the first axial position, a lower shoulder for engagement with the wiper in the second axial position, and a clearance path between the upper and lower shoulders for allowing viscous flow past the wiper when the flow tube is moved between the first and second axial positions.