Abstract: A valve bypass tool for an implantable medical device (IMD) delivery system includes a back panel and a tube connected to the back panel and extending from the back panel to a distal end of the tube. The back panel defines an inlet opening. The tube is cylindrical and the distal end of the tube is configured to dilate a seal of an access introducer. The tube defines a channel therethrough that aligns with and is open to the inlet opening in the back panel. The inlet opening and the channel of the tube are sized to receive an IMD therethrough.

Abstract: Provided herein are methods, compositions and articles of manufacture for use in connection with cell therapy involving the administration of one or more doses of a therapeutic T cell composition. The cells of the T cell composition express recombinant receptors such as chimeric receptors, e.g. chimeric antigen receptors (CARs) or other transgenic receptors such as T cell receptors (TCRs). Features of the provided embodiments, including the numbers of cells or units of cells administered and/or the potency of administered cells, provide various advantages, such as lower risk of toxicity in subjects administered the T cell compositions.

Abstract: Various embodiments set forth systems and techniques for evaluating media content items. The techniques include receiving visual feedback associated with one or more audience members viewing a first media content item; analyzing the visual feedback to generate one or more emotion signals based on the visual feedback; and generating a set of features associated with the one or more audience members viewing the first media content item based on the one or more emotion signals.

Abstract: A system and method for segmenting an anatomical structure in ultrasound imaging data. First ultrasound imaging data of a first region, which includes the anatomical structure, is acquired at a high resolution. Second ultrasound imaging data of a second region, which includes a region neighboring the first region, is acquired at a low resolution. The first and second ultrasound imaging data are processed to segment the anatomical structure.

Abstract: The present invention relates to segmentation. In order to provide a facilitated way of providing enhanced segmentation, a device (10) for enhanced segmentation via an interface is provided. The device comprises a data processor (12), and a data exchange interface (14). The data processor is configured to provide a base segmentation of a region of interest of a subject; wherein the base segmentation comprises a base plurality of information; to generate a reduced segmentation from the base segmentation; wherein the reduced segmentation comprises a reduced plurality of information; and wherein the reduced plurality of information comprises less information than the base plurality of information. The data exchange interface is configured to provide the reduced segmentation to a secondary data processing (18) for further processing to generate secondary data.

Abstract: A system, device, and methods for providing protection of an appendage of a human or animal is provided. The protective system can be a protective boot that includes a cage sized and configured to follow the contours of the distal limb of an animal such as a horse. A plurality of openings are defined in the cage. The cage provides protection of the distal limb and permeability of air flow towards and/or around the distal limb.

Abstract: In an embodiment a method for producing an inductive component includes applying a conductive material and an insulating material in an additive manufacturing process. The conductive material forms at least one winding having a plurality of superimposed turns and the insulating material forms a carrier for the at least one winding. The turns are connected to form a spiral-shaped winding.

Abstract: A valve suitable for an air spring includes a housing body with a central longitudinal axis and channel. The housing body has a first valve opening fluidically connectable to an air spring volume, a second valve opening fluidically connectable to an air supply, which is fluidically connectable to an air spring volume, and a second valve opening which is fluidically connectable to an air supply. Each valve opening is fluidically connected or selectively connectable to the channel. A pressure limiter is provided to limit the pressure flowing out of the second valve opening, the pressure limiter including a third sealing agent and a second sealing agent associated with the second valve opening and selectively closing an opening, wherein pressurization of at least the third sealing agent displaces the second sealing agent due to the forced coupling such that it closes the corresponding opening or reduces the effective opening cross-section.

Abstract: Disclosed is a smart cage system for housing and assaying multiple vertebrate animals having at least one inner and outer housing assembly including at least one controller designed to monitor and record data from sensors, the at least one or more sensors operationally synchronized at least one or more of before, in real time, and after sensing an action, wherein data captured by each at least one or more sensors can be synchronized by way of at least one time measuring device. A multi object tracking software system is operationally coupled to at least one optical sensor by the at least one controller, designed to track individuals of the multiple vertebrate animals. At least the outer housing assembly includes at least one or more from a group of ports, slots, shelves, pockets, hooks, fasteners, and sleeves each designed to retain sensors and other elements.

Abstract: Antimicrobial compositions comprising at least an amine-based antimicrobial and an alkanolamine are disclosed. The disclosed compositions may be free of quaternary ammonium compounds. The disclosed compositions have antimicrobial properties and rapid efficacy against yeast and bacteria.

Abstract: Disclosed are photoactivable fluorescent dye compounds of formula I: wherein: n=0, 1, 2, 3; X is selected from O, CRR?, SiRR? and GeRR?, where R and R? represent independently alkyl, cycloalkyl, alkenyl, alkynyl or aryl; Y is H, SO3H or SO3M, with M being a positively charged counterion, in particular selected from NH4+ and cations of organic ammonium compounds; R1 is H, CO2H, C(O)NH-linker-CO2H, C(O)O-ligand, C(O)NH-ligand or C(O)NH-linker-ligand; R2 may represent H, unsubstituted or substituted alkyl (including cycloalkyl); R3 and R4 may represent independently H or F; R5 is H, Me, CO2H, C(O)NH-linker-CO2H, C(O)O-ligand, C(O)NH-ligand or C(O)NH-linker-ligand; wherein the ligand moiety at each occurrence represents a reactive group or tag, capable to form a covalent or non-covalent bond or molecular complex with a target chemical entity or substance. Methods of using the compounds in imaging of fixed and living cells are also disclosed.

Abstract: Systems, methods, and computer-readable media are disclosed for systems and methods for automated deployment of decoy production networks. Example methods may include detecting, by one or more computer processors coupled to memory, an unauthorized user in a production network environment, determining a payload associated with the unauthorized user, where the payload includes at least one of a computer-executable payload or a data payload that the unauthorized user is attempting to transfer to the production network environment, and initiating a first virtual decoy production network environment. Methods may include causing the computer-executable payload to be executed in the first virtual decoy production network environment, and recording telemetry data associated with execution of the computer-executable payload in the first virtual decoy production network environment.

Abstract: A cell culture bioreactor is disclosed that has a cell culture vessel with an interior reservoir to contain a cell substrate, an inlet fluidly connected to the reservoir, and an outlet fluidly connect to the reservoir. The bioreactor also has a sensor system for measuring impedance within the reservoir. The sensor system includes a pair of electrodes that are spaced apart from each other with at least a portion of the cell substrate disposed between the pair of electrodes. Each electrode of the pair of electrodes includes a plurality of pores to allow at least one of cells and culture media to flow through the electrode.

Abstract: According to an aspect, there is provided a computer-implemented method of operating a visual data delivery system.

Abstract: The invention relates to an ultrasound system for imaging a volumetric region comprising a region of interest (ROI). The system comprises a probe; an ultrasound wave controlling unit adapted to control ultrasound wave transmission and provide ultrasound image data of the volumetric region; an image processor; and a ROI identifier, which is adapted to generate identification data indicating the ROI within the volumetric region; wherein the ultrasound wave transmission is configurable by a plurality of use cases in response to respective identifiers of said use cases, each use case being associated with a particular imaging procedure and comprising an anatomical model for said imaging procedure; and wherein the ROI identifier is configurable by the respective anatomical models of said use cases. A method of configuring such an ultrasound system is also disclosed.

Abstract: Described herein are methods and kits for selective and sensitive activity measurement of human coagulation factor VIII (FVIII).

Abstract: A system includes a processor configured to wirelessly receive vehicle usage data. The processor is also configured to aggregate received data over time. The processor is further configured to classify vehicle usage into a predetermined category based on the aggregated received data. Also, the processor is configured to access a set of maintenance recommendations associated with the predetermined category and send a maintenance recommendation based on a correspondence between the aggregated data and a value associated with one of the maintenance recommendations.

Abstract: Described herein are Zika virus vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.

Abstract: The invention provides for a method for switching between fields of view of an ultrasound probe. The method begins by obtaining an anatomical model representing a region of interest of a subject and establishing a first field of view relative to an ultrasonic probe, wherein the first field of view comprises an initial portion of the region of interest. Ultrasound data is then obtained from the first field of view by way of the ultrasonic probe and a first anatomical feature is identified within the first field of view based on the ultrasound data. A location in digital space of the first field of view relative to the anatomical model is determined based on the first anatomical feature. A second field of view is then established based on the anatomical model and the first field of view, wherein the first field of view functions as a reference field of view. The field of view is then switched from the first field of view to the second field of view.

Abstract: A battery module for a vehicle, in particular for an aircraft, comprises a housing, a cell stack accommodated in the housing, an internal channel system for heat transfer fluid disposed in the housing, a fluid inlet connector and a fluid outlet connector connected to the internal channel system and adapted to being connected to an external thermal management system, wherein the fluid inlet connector and the fluid outlet connector are self-sealing connectors molded into the housing, preferably self-sealing and dripless connectors.