Abstract: The invention relates to means and methods for preparing aqueous composition comprising aluminium and a protein said composition comprising less than 700 ppm heavy metal on the basis of weight with respect to the aluminium content. The invention further relates to aqueous compositions comprising a protein and an aluminium-salt, said composition comprising less than 350 ppb heavy metal based on the weight of the aqueous composition.

Abstract: An ultrasound control unit (12) is for configuring visualization of ultrasound data using in use a display unit. The control unit is adapted to acquire ultrasound image data and to automatically control visualization of the most relevant parts and views the data, based on current levels of a number of different monitored physiological parameters. In particular, responsively to one of the physiological parameters entering or leaving a pre-defined range of values (e.g. representative of an alert or normal condition respective for the patient), the control unit determines a most appropriate anatomical region within the image data for representing the changed physiological parameter, and a most useful visualization mode (e.g. view) for presenting or showing that anatomical region within the image data. One or more display frames are generated which show the anatomical region visualized in accordance with the selected visualization mode.

Abstract: Disclosed are photoactivable fluorescent dye compounds of formula I: wherein: n=0, 1, 2, 3; X is selected from O, CRR?, SiRR? and GeRR?, where R and R? represent independently alkyl, cycloalkyl, alkenyl, alkynyl or aryl; Y is H, SO3H or SO3M, with M being a positively charged counterion, in particular selected from NH4+ and cations of organic ammonium compounds; R1 is H, CO2H, C(O)NH-linker-CO2H, C(O)O-ligand, C(O)NH-ligand or C(O)NH-linker-ligand; R2 may represent H, unsubstituted or substituted alkyl (including cycloalkyl); R3 and R4 may represent independently H or F; R5 is H, Me, CO2H, C(O)NH-linker-CO2H, C(O)O-ligand, C(O)NH-ligand or C(O)NH-linker-ligand; wherein the ligand moiety at each occurrence represents a reactive group or tag, capable to form a covalent or non-covalent bond or molecular complex with a target chemical entity or substance. Methods of using the compounds in imaging of fixed and living cells are also disclosed.

Abstract: Described herein are Zika virus vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.

Abstract: Described herein are improved purification methods for virus vaccines and compositions. Also described are Zika, Chikungunya, dengue and yellow fever vaccines and methods of producing and administering said vaccines to subjects in need thereof.

Abstract: An ultrasound control unit (10) is for coupling with an ultrasound transducer unit (12). The control unit is adapted to control a drive configuration or setting of the transducers of the transducer unit, each drive setting having a known power consumption level associated with it. The control unit includes a control module (20) adapted to adjust the drive setting from a first setting to a second setting, the second having a lower associated power consumption that the first. The second setting is tested by an analysis module (16), the analysis module adapted to determine a measure of reliability of ultrasound data acquired by the transducer unit, for the purpose of deriving at least one physiological parameter, when configured in the second setting. The second setting is only used if its determined reliability passes a pre-defined reliability condition.

Abstract: An apparatus (20) and method (10) for rendering a tree structure in a GUI depending on a position of a pointing cursor relative to the rendered tree use the cursor position with respect to the tree to control which tree branches to expand/collapse automatically. They reconfigure the tree view for compact presentation without need for explicit expand/collapse operations. A tree view is generated (11). A cursor position relative to the view is determined (14), consisting of first and second position values according to first and second directions. The branch the cursor position is aligned with according to the first direction is automatically selected as active branch (15). Sub-levels of that branch to be expanded are determined (16), depending on the second position value relative to indentations of the sub-levels, and the tree view is automatically updated by expanding the determined sub-levels of the active branch and collapsing other branches (17).

Abstract: A pressure sensor device includes a semiconductor die having a die surface that includes a pressure sensitive area; and a bond wire bonded to a first peripheral region of the die surface and extends over the die surface to a second peripheral region of the die surface, wherein the pressure sensitive area is interposed between the second peripheral region and the first peripheral region, wherein the bond wire comprises a crossing portion that overlaps an area of the die surface, and wherein the crossing portion extends over the pressure sensitive area that is interposed between the first and the second peripheral regions.

Abstract: Disclosed are an imaging system (10) or an interventional tool, such as a catheter (20), having a first ultrasound transducer array (23) and a second ultrasound transducer array (21) spaced by a fixed distance (D) from each other; wherein both arrays may be used to generate diagnostic images; and a processing arrangement (31, 32) to process a first sensor signal indicative of the first array imaging a reference location (X) at a first point in time, and to process a second sensor signal indicative of the second array imaging the reference location at a second point in time; and determine a translation (pullback) speed of the catheter from the set distance and the difference between the first point in time and the second point in time. Alternatively, a catheter may be provided comprising an ultrasound transducer array at a distal end of the catheter, and two pressure sensors for determining the translation speed.

Abstract: An ultrasound system is disclosed comprising an ultrasound transducer array (100) comprising a plurality of ultrasound transducer cells (130), each of said cell having an independently adjustable position and/or orientation such as to conform an ultrasound transmitting surface of the cell to a region of a body and a controller (140). The controller is configured to register the respective ultrasound transducer cells by simultaneously operating at least two ultrasound transducer cells in a transmit mode in which the cells transmit distinguishable ultrasound signals and operating the remaining ultrasound transducer cells in a receive mode.

Abstract: A system having an X-ray imaging device for capturing an X-ray image on an imaging film, and a device for reading out the imaging film. The imaging film includes a data carrier, and the X-ray imaging device and/or readout device comprises includes a data device that has a write/read device for writing, on the data carrier, imaging parameters relating to the X-ray image capture and for reading information that is stored on the data carrier, the write/read device being configured to transmit the read information to the readout device such that the imaging parameters in force when capturing the X-ray image are available to the readout device for an imaging film readout. A method for providing information for a readout device is also provided.

Abstract: A system that comprises an X-ray imaging device for capturing an X-ray image on an imaging film, and a device for reading out said imaging film. The imaging film includes an optically readable marking, and the X-ray imaging device and/or the readout device includes a device for reading information stored on the data carrier, the data device being designed to register the optically readable marking using said readout device. A method for providing information for a readout device is also disclosed.

Abstract: There is provided a method and apparatus for refining a model of an anatomical structure in an image. A model for the anatomical structure in the image is acquired. The model comprises a plurality of control points, each control point corresponding to a feature in the anatomical structure. The model is placed in the image with respect to the anatomical structure. Based on a user input received to adjust the model in the image, a position of at least one of the plurality of control points is adjusted to alter a shape of the model to the anatomical structure in the image, wherein adjustment of the position of one or more of the at least one control points is restricted based on information relating to the at least one control point.

Abstract: The invention relates to means and methods for preparing aqueous composition comprising aluminium and a protein said composition comprising less than 700 ppm heavy metal on the basis of weight with respect to the aluminium content. The invention further relates to aqueous compositions comprising a protein and an aluminium-salt, said composition comprising less than 350 ppb heavy metal based on the weight of the aqueous composition.

Abstract: A controller (260) for identifying rotation of an interventional medical device (252) includes a memory that stores instructions and a processor that executes the instructions. When executed by the processor, the instructions cause the controller (260) to execute a process that includes receiving (S410) a first signal emitted from the interventional medical device (252) and corresponding to a first predetermined direction relative to the interventional interventional medical device (252) relative to a fixed rotation.

Abstract: The application discloses a computer-implemented method (100) of providing a model for estimating an anatomical body measurement value from at least one 2-D ultrasound image including a contour of the anatomical body, the method comprising providing (110) a set of 3-D ultrasound images of the anatomical body; and, for each of said 3-D images, determining (120) a ground truth value of the anatomical body measurement; generating (130) a set of 2-D ultrasound image planes each including a contour of the anatomical body, and for each of the 2-D ultrasound image planes, extrapolating (140) a value of the anatomical body measurement from at least one of an outline contour measurement and a cross-sectional measurement of the anatomical body in the 2-D ultrasound image plane; and generating (150) said model by training a machine-learning algorithm to generate an estimator function of the anatomical body measurement value from at least one of a determined outline contour measurement and a determined cross-sectional me

Abstract: A system and method provides for multi-party communication including engaging a network communication engine from a mobile communication interface and providing a user identification and a location indicator to the network communication engine. The method and system further includes receiving in the mobile communication interface a plurality of communication channels based on at least one of: the user identification and the location indicator and in response to a user selection of a selected communication channel, transmitting a channel engagement request to the network communication engine requesting connection of the user to the selected communication channel.

Abstract: A system and method for multi-party communication includes determining a trending common identifier within a media platform and generating a communication channel within a communication platform based on the common identifier. The method and system includes, in response to a join request from each of a plurality of users, connecting the plurality of users to the communication channel, where the communication channel is an open communication channel for active audio communication between the plurality of users across the communication platform and facilitating audio communication between the plurality of users, including providing a visual display on the communication platform, including visual display of the active audio communication across the communication platform.

Abstract: A pressure sensor device includes a semiconductor die of the pressure sensor device and a bond wire of the pressure sensor device. A maximal vertical distance between a part of the bond wire and the semiconductor die is larger than a minimal vertical distance between the semiconductor die and a surface of a gel covering the semiconductor die.

Abstract: Specified is a water supply apparatus, a mixing apparatus (1) being provided for mixing, in a mixing container (3), water conveyed in the mixing apparatus (1). Arranged relative to the mixing container (3) is a base apparatus (2) which has a base chamber (9) that is hydraulically connected to a water pipe (11, 12, 13) of the water supply apparatus and has an opening to the surroundings. A sealing device (10) is installed in the base chamber (9) for the purpose of closing off the opening of the base chamber (9) from the surroundings. The sealing device (10) has a weak point wall region (17) whose pressure strength is lower than the pressure strength of wall regions of all the other components of the water supply apparatus which, in the operating state, enclose cavities that can be filled with water, and which separate these cavities that can be filled with water from the surroundings.