Patents by Inventor Michael Zhang

Michael Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11075265
    Abstract: After forming a laterally contacting pair of a semiconductor fin and a conductive strap structure overlying a deep trench capacitor embedded in a substrate and forming a gate stack straddling a body region of the semiconductor fin, source/drain regions are formed in portions the semiconductor fin located on opposite sides of the gate stack by ion implantation. Next, a metal layer is applied over the source/drain region and subsequent annealing consumes entire source/drain regions to provide fully alloyed source/drain regions. A post alloyzation ion implantation is then performed to introduce dopants into the fully alloyed source/drain regions followed by an anneal to segregate the implanted dopants at interfaces between the fully alloyed source/drain regions and the body region of the semiconductor fin.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: July 27, 2021
    Assignee: International Business Machines Corporation
    Inventors: Michael A. Guillorn, Fei Liu, Zhen Zhang
  • Publication number: 20210220273
    Abstract: Disclosed are cationic lipids which are compounds of Formula I. Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.
    Type: Application
    Filed: May 30, 2019
    Publication date: July 22, 2021
    Inventors: Yi Zhang, Shrirang Karve, Frank DeRosa, Michael Heartlein
  • Publication number: 20210224673
    Abstract: Certain aspects involve optimizing neural networks or other models for assessing risks and generating explanatory data regarding predictor variables used in the model. In one example, a system identifies predictor variables. The system generates a neural network for determining a relationship between each predictor variable and a risk indicator. The system performs a factor analysis on the predictor variables to determine common factors. The system iteratively adjusts the neural network so that (i) a monotonic relationship exists between each common factor and the risk indicator and (ii) a respective variance inflation factor for each common factor is sufficiently low. Each variance inflation factor indicates multicollinearity among the common factors. The adjusted neural network can be used to generate explanatory indicating relationships between (i) changes in the risk indicator and (ii) changes in at least some common factors.
    Type: Application
    Filed: April 2, 2021
    Publication date: July 22, 2021
    Inventors: Matthew TURNER, Michael MCBURNETT, Yafei ZHANG
  • Publication number: 20210224648
    Abstract: Described are a system, method, and computer program product for multivariate event prediction using multi-stream recurrent neural networks. The method includes receiving event data from a sample time period and generating feature vectors for each subperiod of each day. The method also includes providing the feature vectors as inputs to a set of first recurrent neural network (RNN) models and generating first outputs for each RNN node. The method further includes merging the first outputs for each same subperiod to form aggregated time-series layers. The method further includes providing the aggregated time-series layers as an input to a second RNN model and generating final outputs for each RNN node of the second RNN model.
    Type: Application
    Filed: January 14, 2021
    Publication date: July 22, 2021
    Inventors: Zhongfang Zhuang, Michael Yeh, Liang Wang, Wei Zhang, Junpeng Wang
  • Publication number: 20210221868
    Abstract: Provided herein are chimeric antigen receptors (CARs), such as those specific for BCMA, that have improved properties, including increased CAR T cell binding to BCMA and improved CAR T cell killing of BCMA-expressing cancer cells. Use of the CARs in immune cells (e.g., T cells), compositions (e.g., CARs and nucleic acid constructs encoding the same), and methods are also contemplated.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 22, 2021
    Applicant: Cartesian Therapeutics, Inc.
    Inventors: Yi Zhang, C. Andrew Stewart, Metin Kurtoglu, Murat Kalayoglu, Michael S. Singer
  • Publication number: 20210220404
    Abstract: The invention provides immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions and methods thereof.
    Type: Application
    Filed: November 25, 2020
    Publication date: July 22, 2021
    Inventors: Aida Abujoub, John Blankenship, Attilio Bondanza, Jennifer Brogdon, Dexiu Bu, Serena De Vita, Glenn Dranoff, Boris Engels, Tony Fleming, Brian Walter Granda, Michael R. Greene, Carla Patricia Guimaraes, Anniesha Hack, Brian Holmberg, Connie Hong, Lu Huang, Olja Kodrasi, Joni Waiee Lam, Hyungwook Lim, Elizabeth Dorothy Pratico, Andrew Price, Akash Sohoni, Andrew Marc Stein, Louise Treanor, Chonghui Zhang, Xu Zhu
  • Patent number: 11065307
    Abstract: Among other things, the present invention provides methods and compositions of treating Sanfilippo syndrome type B (Sanfilippo B) by, e.g., intrathecal (IT) administration of a Naglu protein. A suitable Naglu protein can be a recombinant, gene-activated or natural protein. In some embodiments, a suitable Naglu protein is a recombinant Naglu protein. In some embodiments, a recombinant Naglu protein is a fusion protein containing a Naglu domain and a lysosomal targeting moiety. In some embodiments, the lysosomal targeting domain is an IGF-II moiety.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: July 20, 2021
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventors: Michael F. Concino, Pericles Calias, Jing Pan, Kevin Holmes, Paolo Martini, Alla Romashko, Muthuraman Meiyappan, Bohong Zhang, Andrea Iskenderian, Dianna Lundberg, Angela Norton, Bettina Strack-Logue, Huang Yan, Mary Alessandrini, Richard Pfeifer
  • Patent number: 11070300
    Abstract: An electronic device may be provided with wireless circuitry that is tested in a test system. The test system may include test probes. Circuitry under test may wirelessly transmit test signals. The test probes may receive the test signals at multiple locations. Circuitry may measure direct current (DC) voltages generated by the test probes and may convert the voltages to electric field magnitudes. A test host may process the electric field magnitudes to determine whether the circuitry under test exhibits a satisfactory radiation pattern. The test probes may include dielectric substrates and one or more dipole elements coupled to respective diodes. The dipole elements may include indium tin oxide (ITO) and may include first and second sets of orthogonal dipole elements. Transmission lines coupled to the dipole elements may include ITO and may form low pass filters that convert rectified voltages produced by the diodes into the DC voltages.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: July 20, 2021
    Assignee: Apple Inc.
    Inventors: Aaron J. Cooper, Amin Tayebi, Breanna E. Bredesen, Carlo Di Nallo, Michael J. Williams, Nikolaj P. Kammersgaard, Qian Zhang, Tyler R. Roschuk
  • Publication number: 20210217974
    Abstract: A variety of hexacoordinate pincer complexes are described herein having electronic structure advantageous for electronic and/or optoelectronic applications. In some embodiments, the pincer complexes are luminescent, exhibiting fluorescence and/or phosphorescence. Briefly, a hexacoordinate complex comprises a central atom selected from the group consisting of silicon, germanium, and tin, and two pincer ligands bound to the central atom, wherein the hexacoordinate complex is luminescent. In another aspect, a hexacoordinate complex comprises a central atom selected from the group consisting of silicon, germanium and tin, and two pincer ligands bound to the central atom, wherein the difference between the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) of the hexacoordinate complex is at least 1.5 eV.
    Type: Application
    Filed: May 29, 2019
    Publication date: July 15, 2021
    Inventors: Thomas Andrew SCHMEDAKE, Michael George WALTER, Yong ZHANG, Margaret KOCHERGA
  • Publication number: 20210217615
    Abstract: Methods of improved selectively for SAM-based selective depositions are described. Some of the methods include forming a SAM on a second surface and a carbonized layer on the first surface. The substrate is exposed to an oxygenating agent to remove the carbonized layer from the first surface, and a film is deposited on the first surface over the protected second surface. Some of the methods include overdosing a SAM molecule to form a SAM layer and SAM agglomerates, depositing a film, removing the agglomerates, reforming the SAM layer and redepositing the film.
    Type: Application
    Filed: March 10, 2021
    Publication date: July 15, 2021
    Applicant: Applied Materials, Inc.
    Inventors: Chang Ke, Michael S. Jackson, Liqi Wu, Lei Zhou, Shuyi Zhang, David Thompson, Paul F. Ma, Biao Liu, Cheng Pan
  • Publication number: 20210213140
    Abstract: Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.
    Type: Application
    Filed: May 29, 2019
    Publication date: July 15, 2021
    Inventors: Yi Zhang, Shrirang Karve, Frank DeRosa, Michael Heartlein
  • Publication number: 20210215003
    Abstract: A cutting element has a cutting face at an opposite axial end from a base, a side surface extending from the base to the cutting face, an edge formed at the intersection between the cutting face and the side surface, and an elongated protrusion formed at the cutting face and extending between opposite sides of the edge, wherein the elongated protrusion has a geometry including a border extending around a concave surface and sloped surfaces extending between the border and the edge, and wherein the concave surface has a major axis dimension measured between opposite sides of the border and a minor axis dimension measured perpendicularly to the major axis dimension and ranging from 50 percent to 99 percent of the major axis dimension.
    Type: Application
    Filed: January 8, 2021
    Publication date: July 15, 2021
    Inventors: Manoj Mahajan, John Daniel Belnap, Xiaoge Gan, Yi Fang, Cheng Peng, Lynn Belnap, Youhe Zhang, Michael George Azar, Venkatesh Karuppiah, Anthony LeBaron, Xian Yao
  • Publication number: 20210214384
    Abstract: The present disclosure relates to analogs of N-acetyl glucosamine fluorinated at 4- and/or 6-position(s) and derivatives of xylose at anomeric position for the treatment of a neurological disease, inflammation, cancer and a central nervous system injury.
    Type: Application
    Filed: May 31, 2019
    Publication date: July 15, 2021
    Inventors: Voon Wee YONG, Chang-Chun LING, Erin Laurel STEPHENSON, Ping ZHANG, Michael Bradley KEOUGH, Khalil Sherali RAWJI
  • Patent number: 11037301
    Abstract: The present disclosure relates to a target object detection method, a readable storage medium and an electronic device. The method is periodically executed and the method includes: identifying a target object based on first N frames of image data obtained within a current execution period, wherein N is a positive integer, and N is less than the total number of frames of image data that can be obtained within the current execution period; and if the target object is identified, tracking the target object based on the obtained image data within the remaining time period of the current execution period. In the above technical solution, when the target object is identified, the identified target object is tracked within the remaining time period of the current execution period, so that the data calculation amount can be effectively reduced.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: June 15, 2021
    Assignee: NEUSOFT CORPORATION
    Inventors: Menghui Yang, Michael Zhang
  • Patent number: 10896626
    Abstract: The present disclosure relates to a method, a computer readable storage medium and electronic equipment for analyzing driving behavior. The method comprises: acquiring image information in a running process of a target vehicle; acquiring time series data in the running process according to the image information; and acquiring a target driving behavior score for the running process according to the time series data.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: January 19, 2021
    Assignee: NEUSOFT CORPORATION
    Inventors: Michael Zhang, Murphy Yang, Jian Yao
  • Patent number: 10881309
    Abstract: The arterial health of an individual can be determined by: attaching a fingertip photopiethysmography device to a fingertip of the hand of the elevated arm of the individual; measuring the analog pulse contour of the individual using the fingertip photopiethysmography device; digitizing the analog pulse contour; analyzing the digitized pulse contour for stable waveforms; processing the stable waveforms of the digitized pulse contour using dynamic time warping; comparing the stable waveforms to a library of known disease state waveforms; and assigning a most probable disease state for the individual based on said comparison.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: January 5, 2021
    Assignee: Arterial Stiffness Inc.
    Inventors: Michael Zhang, Zhaopeng Fan, Marshall Ring, Sara Korosch, David Keenan, Gerald Lefevre
  • Publication number: 20200364472
    Abstract: The present disclosure relates to a vehicle tracking method, a computer readable storage medium, and an electronic device. The method includes: determining a predicted value of state information of a target tracking vehicle based on a sequential Kalman filtering model according to a most recently acquired tracking value of the state information of the target tracking vehicle, wherein the state information at least includes location information; obtaining a detected value of the state information of the target tracking vehicle; and in response to the obtained detected value, acquiring a new tracking value of the state information of the target tracking vehicle based on the sequential Kalman filtering model according to the detected value and the most recently determined predicted value. Through the above technical solution, the tracking value of the state information of the target tracking vehicle may be determined more accurately.
    Type: Application
    Filed: September 9, 2019
    Publication date: November 19, 2020
    Inventors: Yuan Iiu, Michael Zhang, Menghui Yang
  • Publication number: 20200327677
    Abstract: The present disclosure relates to a target object detection method, a readable storage medium and an electronic device. The method is periodically executed and the method includes: identifying a target object based on first N frames of image data obtained within a current execution period, wherein N is a positive integer, and N is less than the total number of frames of image data that can be obtained within the current execution period; and if the target object is identified, tracking the target object based on the obtained image data within the remaining time period of the current execution period. In the above technical solution, when the target object is identified, the identified target object is tracked within the remaining time period of the current execution period, so that the data calculation amount can be effectively reduced.
    Type: Application
    Filed: September 9, 2019
    Publication date: October 15, 2020
    Inventors: Menghui Yang, Michael Zhang
  • Patent number: D912795
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: March 9, 2021
    Assignee: LEADYOUNG TECHNOLOGY CO., LTD
    Inventors: Yong Wang, Xiaofeng Wu, Michael Zhang
  • Patent number: RE48654
    Abstract: An optical device that includes means for thermal stabilization and control is described. The optical device can be a ring resonator, or another device that requires accurate control of the phase of the optical signal. In an example involving an optical resonator, a thermal stabilization system includes a temperature sensor, a control circuit, and a heater local to the resonator. The temperature sensor can be a bandgap temperature sensor formed of a pair of matched p/n junctions biased in operation at different junction currents.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: July 20, 2021
    Assignee: Nokia Solutions & Networks Oy
    Inventors: Yi Zhang, Shuyu Yang, Kishore Padmaraju, Michael J. Hochberg