Abstract: Provided is a system for analyzing a multivariate time series that includes at least one processor programmed or configured to receive a time series of historical data points, determine a historical time period, determine a contemporary time period, determine a first time series of data points associated with a historical transaction metric from the historical time period, determine a second time series of data points associated with a historical target transaction metric from the historical time period, determine a third time series of data points associated with a contemporary transaction metric from the contemporary time period, and generate a machine learning model, wherein the machine learning model is configured to provide an output that comprises a predicted time series of data points associated with a contemporary target transaction metric. Methods and computer program products are also provided.

Abstract: Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

Abstract: A storage bag for storing agricultural products comprising a polymeric tube formed to include a storage space therein and a fill aperture arranged to open into the storage space at a first end of the polymeric tube. The polymeric tube is formed from a film.

Abstract: A substrate includes a first area in which a laser array chip is disposed. The substrate includes a second area in which a planar lightwave circuit is disposed. The second area is elevated relative to the first area. A trench is formed in the substrate between the first area and the second area. The substrate includes a third area in which an optical fiber alignment device is disposed. The third area is located next to and at a lower elevation than the second area within the substrate. The planar lightwave circuit has optical inputs facing toward and aligned with respective optical outputs of the laser array chip. The planar lightwave circuit has optical outputs facing toward the third area. The optical fiber alignment device is configured to receive optical fibers such that optical cores of the optical fibers respectively align with the optical outputs of the planar lightwave circuit.

Abstract: Provided are processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate, or a salt, solvate, hydrate, enantiomer, mixture of enantiomers, or isotopologue thereof. Also provided are solid forms of various intermediates and products obtained from the processes.

Abstract: A system may determine configuration information associated with a power system for a work site that includes one or more power sources. The system may determine respective operation parameters of the one or more power sources and one or more performance criteria associated with the power system. The system may determine a baseline operation plan for the power system. The system may identify an optimization analysis technique and may process, using the optimization analysis technique, the configuration information associated with the power system, the respective operation parameters of the one or more power sources, and the one or more performance criteria associated with the power system to generate the optimized operation plan for the power system. The system may cause, based on the baseline operation plan for the power system and the optimized operation plan for the power system, one or more actions to be performed.

Abstract: A door interface system for a vehicle door includes a sensor and a visual indicator. The sensor may be a proximity sensor and may be positioned proximate to the visual indicator such that it will detect an object proximate to the proximity sensor. The visual indicator may convey the position of the sensor and/or a status of the vehicle door. The door interface system is configured to control the vehicle door based at least in part on detecting an object proximate the visual indicator.

Abstract: Phospholipid-conjugated Ags were used as an agnostic delivery platform to cell type, activation state, and inherent uptake capabilities for engineering APCs to control Ag-specific cellular immune responses. Lipid-mediated delivery (termed depoting) of MHC class I and II-restricted Ags successfully loaded resting polyclonal B cells, CD40? activated B cells, and DCs in a dose-dependent manner for priming Ag-specific CD8+ and CD4+ T cells, respectively. When lipid-conjugated Ags were paired with polymer-conjugated Ags and incorporated in nanoparticles (NPs), diverse APCs with varying NP internalization capabilities all processed the lipid-conjugated Ags via depoting while only DCs processed the PLGA-conjugated Ags via endocytosis. Multivariate analyses of cytokine secretions indicated that lipid-conjugated Ags could be distinctly classified from polymer-conjugated Ags.

Abstract: The invention relates to a non-invasive imaging method of bacteria. One embodiment comprises labeling the bacteria with a radioisotope, then delivering it to the gut of a human or animal. Another embodiment is to label bacteriophages, then administer them to a human or animal, so that they infect (and thus co-localize with) bacteria already resident in the human or animal. The bacteriophage can then be imaged, showing the location of the resident bacteria of interest. In another embodiment, the invention is related more generally to the labelling of bacteria or bacteriophages with a radio-metal or radioisotope to render the labeled gut bacteria and the bacteria in the body visible to nuclear medicine PET and SPECT imaging guided by functional/structural MRI and/or CT imaging.

Abstract: A homogenous mixing apparatus comprises: a circulation unit, a dynamic mixing unit, wherein a feeding port of the first-stage dynamic mixing device communicates with the discharging end of the circulation unit, a discharging port of the third-stage dynamic mixing device communicates with the feeding end of the circulation unit, and each of the dynamic mixing devices comprises a dynamic mixer; and a control unit, configured to be capable of controlling the dynamic mixing unit, so that the dynamic mixers of the first-stage, the second-stage dynamic mixing device, and the third-stage dynamic mixing device are capable of being independently started and shut down and operated at independent rotating speeds, wherein the dynamic mixers each comprise a stator and a rotor, rotating speed ranges of the dynamic mixers of the first-stage, second-stage, and third-stage dynamic mixing device increase in sequence, and distances between the rotors and the stators decrease in sequence.

Abstract: The present disclosure relates to method, storage medium and electronic device for detecting vehicle crashes. The method comprises: acquiring state information of a target vehicle; and determining an event type of the target vehicle according to the state information and a trained convolutional neural network, the event type being any of the following types: a crash event, a near crash event and a baseline event. The event type of the vehicle is determined using the trained convolutional neural network in the present disclosure, so that the accuracy is high; and near crash events can be detected, thus, when a near crash event is detected, the driver can be further alerted or an evading operation is directly performed on the vehicle, so that the safety is improved and the safety of the driver and passengers is guaranteed.

Abstract: Opioids can be detected using a test system with ZnO pillars arranged in an array on a silicon wafer. Silver particles are on a top surface and/or side surface of the ZnO pillars. A sample fluid is applied to the test system. A concentration of an opioid compound in the sample fluid is determined using Surface-Enhanced Raman Spectroscopy of the test system. The sample fluid can be blood or a fluid isolated from blood.

Abstract: A bathtub device for bubble bath physiotherapy, wherein the bathtub body is mounted on the bathtub body support. The exhaust system of the bathtub device is mounted in a space between the bathtub body and the bathtub body support. A fan is configured for delivering gas. The air suction inlet ends of the air suction pipe are configured to be in communication with the upper open side of the bathtub body, and the air suction outlet end is connected to the air inlet side interface device of the fan. The exhaust inlet end of the exhaust pipe is connected to the air outlet side interface device of the fan. The present invention further provides a bubble bath physiotherapy system comprising the bathtub device. By using the bathtub device, a safer bubble bath can be achieved.

Abstract: The present disclosure relates to a vehicle tracking method, a computer readable storage medium, and an electronic device. The method includes: determining a predicted value of state information of a target tracking vehicle based on a sequential Kalman filtering model according to a most recently acquired tracking value of the state information of the target tracking vehicle, wherein the state information at least includes location information; obtaining a detected value of the state information of the target tracking vehicle; and in response to the obtained detected value, acquiring a new tracking value of the state information of the target tracking vehicle based on the sequential Kalman filtering model according to the detected value and the most recently determined predicted value. Through the above technical solution, the tracking value of the state information of the target tracking vehicle may be determined more accurately.

Abstract: The present disclosure relates to a target object detection method, a readable storage medium and an electronic device. The method is periodically executed and the method includes: identifying a target object based on first N frames of image data obtained within a current execution period, wherein N is a positive integer, and N is less than the total number of frames of image data that can be obtained within the current execution period; and if the target object is identified, tracking the target object based on the obtained image data within the remaining time period of the current execution period. In the above technical solution, when the target object is identified, the identified target object is tracked within the remaining time period of the current execution period, so that the data calculation amount can be effectively reduced.

Abstract: The present disclosure relates to a method, a computer readable storage medium and electronic equipment for analyzing driving behavior. The method comprises: acquiring image information in a running process of a target vehicle; acquiring time series data in the running process according to the image information; and acquiring a target driving behavior score for the running process according to the time series data.

Abstract: The arterial health of an individual can be determined by: attaching a fingertip photopiethysmography device to a fingertip of the hand of the elevated arm of the individual; measuring the analog pulse contour of the individual using the fingertip photopiethysmography device; digitizing the analog pulse contour; analyzing the digitized pulse contour for stable waveforms; processing the stable waveforms of the digitized pulse contour using dynamic time warping; comparing the stable waveforms to a library of known disease state waveforms; and assigning a most probable disease state for the individual based on said comparison.

Abstract: The present disclosure relates to a vehicle tracking method, a computer readable storage medium, and an electronic device. The method includes: determining a predicted value of state information of a target tracking vehicle based on a sequential Kalman filtering model according to a most recently acquired tracking value of the state information of the target tracking vehicle, wherein the state information at least includes location information; obtaining a detected value of the state information of the target tracking vehicle; and in response to the obtained detected value, acquiring a new tracking value of the state information of the target tracking vehicle based on the sequential Kalman filtering model according to the detected value and the most recently determined predicted value. Through the above technical solution, the tracking value of the state information of the target tracking vehicle may be determined more accurately.