Abstract: The present disclosure relates to compounds. and to their pharmaceutical compositions. that inhibit dipeptidyl peptidase IV (DPP4). Hie compounds selectively promote the proliferation of alveolar type 2 cells (AEC2s) and are useful in therapeutic methods of treating diseases whose etiology. for example. derives from epithelial degeneration and maladaptive remodeling, such as pulmonary' diseases like idiopathic pulmonary fibrosis (IFF), acute respiratory' distress syndrome (ARDS), and infant respiratory' distress syndromes (IRDS).

Abstract: The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

Abstract: A wave energy converter is provided which includes a nacelle having a starboard side and a port side axis, and housing a power take-off. The wave energy converter also includes at least one buoyancy member coupled to the nacelle, and a ballast tank coupled to the nacelle. The ballast tank, the at least one buoyancy member, and the nacelle, together form a first body, where the first body is coupled to the power take-off. The wave energy converter further includes a float and a drive arm forming a second body, where the second body is rotatably coupled to the first body about a coupling axis, and the second body is coupled to the power take-off. The second body is configured to rotate relative to the first body about the coupling axis within a radial span bounded by a proximal end of the float and a radially distal end of the float.

Abstract: Devices such as multiports comprising connection ports with associated securing features and methods for making the same are disclosed. In one embodiment, the device comprises a shell, at least one connection port, at least one securing feature passageway, and at least one securing feature. The at least one connection port is disposed on the multiport with the at least one connection port comprising an optical connector opening extending from an outer surface of the multiport to a cavity of the multiport and defining a connection port passageway. The at least one securing feature is associated with the connection port passageway, and the at least one securing feature is disposed within a portion of the at least one securing feature passageway.

Abstract: A heat exchange system and a method for reclaiming corrosion inhibitor in a heat exchange system are provided by the present disclosure. The heat exchange system includes a compressor (1), a condenser (2) and an evaporator (3) connected in sequence, and the heat exchange system further includes a system for reclaiming corrosion inhibitor which includes an ejector (6) including a high-pressure fluid inlet (61) connected to an outlet (11) of the compressor, a suction fluid inlet (62) connected to the heat exchange system to extract a liquid-state refrigerant in the heat exchange system, and a fluid outlet (63) leading to bearings of the compressor, wherein a pressurizing device (5) is provided between the outlet of the compressor and the high-pressure fluid inlet of the ejector. The heat exchange system according to the embodiments of the present disclosure can provide sufficient corrosion inhibitor to the bearings of the compressor under various working conditions.

Abstract: New and/or improved coatings, layers or treatments for porous substrates, including battery separators or separator membranes, and/or coated or treated porous substrates, including coated battery separators, and/or batteries or cells including such coatings or coated separators, and/or related methods including methods of manufacture and/or of use thereof are disclosed. Also, new or improved coatings for porous substrates, including battery separators, which comprise at least a matrix material or a polymeric binder, and heat-resistant particles with additional additives, materials or components, and/or to new or improved coated or treated porous substrates, including battery separators, where the coating comprises at least a matrix material or a polymeric binder, and heat-resistant particles with additional additives, materials or components are disclosed.

Abstract: A liquid desiccant regenerator configured to produce a first output stream with a higher concentration of a liquid desiccant than a first input stream. The regenerator also produces a second output stream with a lower concentration of the liquid desiccant than a second input stream. Regeneration of the liquid desiccant in the liquid desiccant regenerator decreases a temperature of the liquid desiccant regenerator. The system includes an air contactor coupled to the first output stream and exposing an input air stream to the first output stream. The first output stream absorbs water from the input air stream to form at least one diluted output desiccant stream. A heat pump of the system is thermally coupled to move the heat from the first output stream to the liquid desiccant regenerator. The heat moved to the liquid desiccant regenerator increases an efficiency of the liquid desiccant regenerator.

Abstract: Provided are bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof, and methods for identifying such bivalent compounds.

Abstract: The present disclosure relates to methods and intermediates useful for preparing a compound of formula I: or a co-crystal, solvate, salt or combination thereof.

Abstract: Provided are electrodes that include an electrode dry mixture and a dry electrolyte material intermixed with the electrode dry mixture; and a binder intermixed with the electrode dry mixture and the dry electrolyte material, said binder comprising fibrils; the electrode dry mixture, dry electrolyte material, and said binder in the form of a dry electrode film. The electrolyte material may include a glass ceramic and, optionally, an air-stabilizing dopant. The glass ceramic may include Li3PS4. The electrodes may include a composite cathode of the dry electrode film and optionally further include a solid-state electrolyte layer. Also provided are methods for forming the electrodes, optionally where the methods may be applicable for a solvent-free process to form electrodes and electrochemical cells and batteries including the electrodes.

Abstract: Improved battery separators, base films or membranes, batteries, cells, devices, systems, vehicles, and/or methods of making and/or using such separators, films or membranes, batteries, cells, devices, systems, vehicles, and/or methods of enhancing battery or cell charge rates, charge capacity, and/or discharge rates, and/or methods of improving batteries, systems including such batteries, vehicles including such batteries and/or systems, and/or the like; biaxially oriented porous membranes, composites including biaxially oriented porous membranes, biaxially oriented microporous membranes, biaxially oriented macroporous membranes, battery separators with improved charge capacities and the related methods and methods of manufacture, methods of use, and the like; flat sheet membranes, liquid retention media; dry process separators; biaxially stretched separators; dry process biaxially stretched separators having a thickness range between about 5 ?m and 50 ?m, preferably between about 10 ?m and 25 ?m, having imp

Abstract: A coating composition comprising (a) a polyester binder material; and (b) a feathering reducing agent. The feathering reducing agent is selected from (i) an acrylic feathering reducing agent comprising a functional group selected from hydroxyl, epoxide, phosphatized epoxide and/or acid-functional; (ii) a hydroxy-functional polyester feathering reducing agent; (iii) a feathering reducing agent comprising a functional group selected from amine, amide, imine and/or nitrile; (iv) a phosphatized epoxy feathering reducing agent; (v) a phenolic resin feathering reducing agent; and/or (vi) a feathering reducing agent comprising an oxazolyl functional group. The invention extends to a substrate coated with the coating composition and use of the coating composition to reduce feathering.

Abstract: An approach is provided for a gaming overlay application to provide automatic in-game subtitles and/or closed captions for video game applications. The overlay application accesses an audio stream and a video stream generated by an executing game application. The overlay application processes the audio stream through a text conversion engine to generate at least one subtitle. The overlay application determines a display position to associate with the at least one subtitle. The overlay application generates a subtitle overlay comprising the at least one subtitle located at the associated display position. The overlay application causes a portion of the video stream to be displayed with the subtitle overlay.

Abstract: System is configured to receive article information corresponding to articles to be transported by computer-controlled vehicles, the articles comprising a first article and a second article, each having a maximum article dimension. System is also configured to assign travel routes about a grid comprising grid cells for the vehicles to travel thereon. The travel route of a first vehicle carrying the first article includes a turning maneuver at a first grid cell. System is configured to control the turning maneuver of the first vehicle in the first grid cell such that there is no contact between the first article carried on the first vehicle with a second article carried on a second vehicle present in a second grid cell that is adjacent to the first grid cell when the first vehicle is undertaking the turning maneuver.

Abstract: A wave energy converter is provided which includes a nacelle having a starboard side and a port side axis, and housing a power take-off. The wave energy converter also includes at least one buoyancy member coupled to the nacelle, and a ballast tank coupled to the nacelle. The ballast tank, the at least one buoyancy member, and the nacelle, together form a first body, where the first body is coupled to the power take-off. The wave energy converter further includes a float and a drive arm forming a second body, where the second body is rotatably coupled to the first body about a coupling axis, and the second body is coupled to the power take-off. The second body is configured to rotate relative to the first body about the coupling axis within a radial span bounded by a proximal end of the float and a radially distal end of the float.

Abstract: Provided are systems for analyzing a relational database using embedding learning that may include at least one processor programmed or configured to generate one or more entity-relation matrices from a relational database and perform, for each entity-relation matrix of the one or more entity-relation matrices, an embedding learning process on an embedding associated with an entity. When performing the embedding learning process on the embedding associated with the entity, the at least one processor is programmed or configured to generate an updated embedding associated with the entity. Computer-implemented methods and computer program products are also provided.

Abstract: Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. The probes exhibit improved performance compared to industry leading dual-stranded probes; particularly in terms of the rate of hybridization.

Abstract: Provided herein are compositions, systems, and methods for delivering cargo to a target cell. The compositions, systems, and methods comprise one or more polynucleotides encoding one or more LTR retroelement polypeptides for forming a delivery vesicle and one or more capture moieties for packaging a cargo within the delivery vesicle. The one or more LTR retroelement polypeptides for forming a delivery vesicle may comprise two or more of an LTR retroelement gag protein, a retroelement envelope protein, a an LTR retroelement reverse transcriptase, or a combination thereof. The LTR retroelement polypeptide alone, the LTR retroelement envelope protein alone, or both the LTR retroelement-derived polypeptide and LTR retroelement envelope protein may be endogenous.

Abstract: Disclosures relate to a sensor system and arrangements having different sized removable spacers. The spacers may be mixed and matched as needed or desired to compensate for misalignment conditions. Further, different spacer combinations and adjustments may be guided by a security management computing device. Variations in configurations of mounting surfaces, such as door and window assemblies, may be accommodated. Alignment of a transmitter or a receiving device, e.g., a magnetic device, with respect to a transmitter or receiving device despite misalignment of the components due to, for example, uneven surfaces of a door or a window, or a respective frame may be achieved.

Abstract: Systems and methods relating to improving the experience of gig-economy workers are disclosed, with particular reference to gig-economy work involving vehicle use. During or after performance of gig-economy work, data automatically collected may be used to generate and present recommendations or education points to gig-economy workers. Such recommendations may include targeted alerts to notify gig-economy workers of high-demand situations or to coordinate between gig-economy workers and gig-economy customers. Alerts may be generated based upon current excess demand for gig-economy services, as well as gig-economy worker availability and preferences. For example, alerts may be generated in response to detecting emergency conditions in an area in order to mobilize a large number of gig-economy transportation service providers.