Patents by Inventor Michihiko Nishigaki
Michihiko Nishigaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11841312Abstract: According to one embodiment, a monitoring device includes a detector unit including an image transfer element comprising an incident surface which allows light to enter from a light-transmissive base material on which a microbody is placed and an emission surface which emits the light entering from the incident surface, which transfers two-dimensional image data of the microbody to a semiconductor optical sensor, and the semiconductor optical sensor which receives light from the emission surface.Type: GrantFiled: December 14, 2022Date of Patent: December 12, 2023Assignee: CYTORONIX INC.Inventors: Kaita Imai, Shouhei Kousai, Michihiko Nishigaki
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Publication number: 20230118112Abstract: According to one embodiment, a monitoring device includes a detector unit including an image transfer element comprising an incident surface which allows light to enter from a light-transmissive base material on which a microbody is placed and an emission surface which emits the light entering from the incident surface, which transfers two-dimensional image data of the microbody to a semiconductor optical sensor, and the semiconductor optical sensor which receives light from the emission surface.Type: ApplicationFiled: December 14, 2022Publication date: April 20, 2023Applicant: CYTORONIX INC.Inventors: Kaita IMAI, Shouhei KOUSAI, Michihiko NISHIGAKI
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Patent number: 11592385Abstract: According to one embodiment, a monitoring device includes a detector unit including an image transfer element comprising an incident surface which allows light to enter from a light-transmissive base material on which a microbody is placed and an emission surface which emits the light entering from the incident surface, which transfers two-dimensional image data of the microbody to a semiconductor optical sensor, and the semiconductor optical sensor which receives light from the emission surface.Type: GrantFiled: September 14, 2020Date of Patent: February 28, 2023Assignee: CYTORONIX INC.Inventors: Kaita Imai, Shouhei Kousai, Michihiko Nishigaki
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Patent number: 11561163Abstract: According to one embodiment, a monitoring device includes a detector unit including an image transfer element comprising an incident surface which allows light to enter from a light-transmissive base material on which a microbody is placed and an emission surface which emits the light entering from the incident surface, which transfers two-dimensional image data of the microbody to a semiconductor optical sensor, and the semiconductor optical sensor which receives light from the emission surface.Type: GrantFiled: September 14, 2020Date of Patent: January 24, 2023Assignee: CYTORONIX INC.Inventors: Kaita Imai, Shouhei Kousai, Michihiko Nishigaki
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Publication number: 20200408663Abstract: According to one embodiment, a monitoring device includes a detector unit including an image transfer element comprising an incident surface which allows light to enter from a light-transmissive base material on which a microbody is placed and an emission surface which emits the light entering from the incident surface, which transfers two-dimensional image data of the microbody to a semiconductor optical sensor, and the semiconductor optical sensor which receives light from the emission surface.Type: ApplicationFiled: September 14, 2020Publication date: December 31, 2020Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Kaita IMAI, Shouhei KOUSAI, Michihiko NISHIGAKI
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Patent number: 10646899Abstract: According to one embodiment, a cell sorter includes a flow channel which supplies a sample liquid containing particles, a plurality of branch channels connected to the flow channel, an image sensor which has a pixel region covering the flow channel and the branch channels, a determination unit which determines the characteristics of the particles in the sample liquid from a measurement signal of the pixel region, and a separation unit guides the particles in the sample liquid to any of the branch channels based on the determination result of the determination unit.Type: GrantFiled: March 8, 2018Date of Patent: May 12, 2020Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Kaita Imai, Shouhei Kousai, Yosuke Akimoto, Michihiko Nishigaki, Yutaka Onozuka, Miyu Nagai
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Patent number: 10533934Abstract: According to one embodiment, a particle inspection system includes a voltage driving circuit which applies a driving voltage for a particle inspection to a particle inspection chip, a current-voltage conversion circuit which converts, into a voltage signal, a current signal output from the particle inspection chip when the driving voltage is applied to the particle inspection chip, a detection circuit which detects, based on the voltage signal, whether the sample liquid is introduced into a detection region of the particle inspection chip, and an analysis circuit which analyzes the fine particle, in the sample liquid based on the voltage signal. The voltage driving circuit varies the driving voltage based on the detection result of the detection circuit.Type: GrantFiled: January 18, 2017Date of Patent: January 14, 2020Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Michihiko Nishigaki, Hiroshi Hamasaki, Naofumi Nakamura, Kentaro Kobayashi, Hiroko Miki
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Publication number: 20190283284Abstract: According to one embodiment, a method of manufacturing a microchannel includes coating a silicone resin onto a mold corresponding to a microchannel and a first opening communicating with the microchannel, curing the silicone resin by light using a mask having a light shielding portion corresponding to the first opening, removing an uncured silicone resin, and releasing the cured silicone resin from the mold.Type: ApplicationFiled: August 27, 2018Publication date: September 19, 2019Applicants: KABUSHIKI KAISHA TOSHIBA, TOSHIBA ELECTRONIC DEVICES & STORAGE CORPORATIONInventors: Michihiko NISHIGAKI, Miyu NAGAI, Shouhei KOUSAI, Yosuke AKIMOTO, Kaita IMAI, Yutaka ONOZUKA
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Patent number: 10379440Abstract: According to one embodiment, a pattern forming method includes forming a resist pattern on a substrate, forming a first silicone resin layer so as to bury the resist pattern on the substrate, pressing a film on the surface of the first silicone resin layer to adhere the film thereto, curing the first silicone resin layer after the adhesion of the film, peeling the film from the first silicone resin layer before or after the curing of the first silicone resin layer, and removing the resist pattern after the peeling of the film.Type: GrantFiled: September 1, 2017Date of Patent: August 13, 2019Assignee: KABUSHIKI KASHIA TOSHIBAInventors: Michihiko Nishigaki, Yutaka Onozuka, Shouhei Kousai, Yosuke Akimoto, Miyu Nagai, Kaita Imai
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Patent number: 10337976Abstract: According to one embodiment, a microanalysis chip includes a substrate, a flow channel in which a sample liquid is allowed to flow, the flow channel being provided on a main surface side of the substrate, a reservoir in which the sample liquid is allowed to be stored, the reservoir being provided on a main surface of the substrate, including a bank having a go-around shape and further including a liquid introduction inlet for connection to an end of the flow channel, the liquid introduction inlet being provided on the main surface of the substrate in the bank, and a filter which is provided between the liquid introduction inlet and the end of the flow channel and includes a first micropore for allowing passage of a fine particle in the sample liquid.Type: GrantFiled: June 5, 2015Date of Patent: July 2, 2019Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Michihiko Nishigaki, Yutaka Onozuka, Kentaro Kobayashi, Hiroshi Hamasaki, Naofumi Nakamura
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Patent number: 10337994Abstract: According to one embodiment, a measuring device for a sample liquid includes a container which stores the sample liquid, the container including a transparent or translucent optical component with an inclined surface to be brought into contact with the sample liquid, an optical sensor provided on a bottom of the container, which detects light from the sample liquid, and a measurement module which measures a concentration of a specific substance contained in the sample liquid, or a liquid height or liquid volume of the sample liquid based on a detected signal of the optical sensor.Type: GrantFiled: September 5, 2017Date of Patent: July 2, 2019Assignee: Kabushiki Kaisha ToshibaInventors: Kaita Imai, Shouhei Kousai, Yosuke Akimoto, Michihiko Nishigaki, Yutaka Onozuka, Miyu Nagai
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Patent number: 10281429Abstract: According to one embodiment, a semiconductor micro-analysis chip includes a first flow channel provided with a substrate surface, the flow channel engraved on the substrate into which a sample liquid can flow, micropore provided with a part of the flow channel, a reservoir provided with at least one end of the flow channel, the reservoir engraved on the substrate for inlet and outlet of the sample liquid, and a first electrode provided with a part of the flow channel or of the reservoir. The electrode is disposed from the bottom surface of the flow channel or of the reservoir to the substrate surface, and a side surface which connects the bottom surface and the substrate surface is tapered for reducing a bend in a height direction of the electrode.Type: GrantFiled: January 18, 2017Date of Patent: May 7, 2019Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Kentaro Kobayashi, Michihiko Nishigaki, Hiroshi Hamasaki, Naofumi Nakamura
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Publication number: 20190084011Abstract: According to one embodiment, a cell sorter includes a flow channel which supplies a sample liquid containing particles, a plurality of branch channels connected to the flow channel, an image sensor which has a pixel region covering the flow channel and the branch channels, a determination unit which determines the characteristics of the particles in the sample liquid from a measurement signal of the pixel region, and a separation unit guides the particles in the sample liquid to any of the branch channels based on the determination result of the determination unit.Type: ApplicationFiled: March 8, 2018Publication date: March 21, 2019Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Kaita IMAI, Shouhei Kousai, Yosuke Akimoto, Michihiko Nishigaki, Yutaka Onozuka, Miyu Nagai
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Patent number: 10126168Abstract: According to one embodiment, an optical sensor includes a first substrate, a first insulating film and a light-shielding film. The first substrate has a light detecting region detecting fluorescence generated from a fluorescent material by light with which irradiation is performed from a lateral side. The first insulating film is provided on the first substrate. The light-shielding film is provided, at least, on a side surface of the first substrate to which the light enters, on a side surface of the first insulating film and above a region excluding a region corresponding to the light detecting region of the first insulating film.Type: GrantFiled: March 5, 2018Date of Patent: November 13, 2018Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Yosuke Akimoto, Shouhei Kousai, Kaita Imai, Michihiko Nishigaki, Yutaka Onozuka, Miyu Nagai
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Publication number: 20180217500Abstract: According to one embodiment, a pattern forming method includes forming a resist pattern on a substrate, forming a first silicone resin layer so as to bury the resist pattern on the substrate, pressing a film on the surface of the first silicone resin layer to adhere the film thereto, curing the first silicone resin layer after the adhesion of the film, peeling the film from the first silicone resin layer before or after the curing of the first silicone resin layer, and removing the resist pattern after the peeling of the film.Type: ApplicationFiled: September 1, 2017Publication date: August 2, 2018Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Michihiko NISHIGAKI, Yutaka ONOZUKA, Shouhei KOUSAI, Yosuke AKIMOTO, Miyu NAGAI, Kaita IMAI
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Publication number: 20180080871Abstract: According to one embodiment, a measuring device for a sample liquid includes a container which stores the sample liquid, the container including a transparent or translucent optical component with an inclined surface to be brought into contact with the sample liquid, an optical sensor provided on a bottom of the container, which detects light from the sample liquid, and a measurement module which measures a concentration of a specific substance contained in the sample liquid, or a liquid height or liquid volume of the sample liquid based on a detected signal of the optical sensor.Type: ApplicationFiled: September 5, 2017Publication date: March 22, 2018Inventors: Kaita Imai, Shouhei Kousai, Yosuke Akimoto, Michihiko Nishigaki, Yutaka Onozuka, Miyu Nagai
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Patent number: 9895691Abstract: According to one embodiment, an analysis package, including a board, an analysis chip provided on the board, the chip including a detector for detecting a particle, a flow channel of a sample liquid, and a liquid receiver of the sample liquid, a first mold layer provided on the analysis chip, the first mold layer including an opening above the liquid receiver, and a second mold layer provided on the board and the first mold layer, the second mold layer including an opening above the opening of the first mold layer, wherein the respective openings of the first and second mold layers are connected above the liquid receiver to allow the sample liquid to be introduced into the liquid receiver from outside.Type: GrantFiled: September 8, 2015Date of Patent: February 20, 2018Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Hiroshi Hamasaki, Michihiko Nishigaki, Yutaka Onozuka, Kentaro Kobayashi, Hiroko Miki, Naofumi Nakamura
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Patent number: 9885680Abstract: According to one embodiment, an analysis package including an analysis chip provided on a main surface of a semiconductor substrate, the chip including a flow channel, both ends of which are open at peripheral parts of the substrate, and a microaperture which is provided in a middle of the flow channel and which allows a particle to pass therethrough, a package board on which the chip is mounted, liquid receivers provided on the package board, the liquid receivers being connected to openings, and electrodes, at least parts of which are provided on parts of bottom surfaces of the liquid receivers, the electrodes being provided at positions corresponding to an upstream side and a downstream side of the microaperture.Type: GrantFiled: September 9, 2015Date of Patent: February 6, 2018Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Hiroshi Hamasaki, Michihiko Nishigaki, Yutaka Onozuka, Kentaro Kobayashi, Hiroko Miki, Naofumi Nakamura
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Patent number: 9770714Abstract: According to one embodiment, an analysis package including a board including an electrical terminal, an analysis chip provided at the board, the chip including a detector for detecting a particle, a flow channel of a sample liquid for particle detection to the detector, and a liquid receiver for introducing the sample liquid into the flow channel, a mold provided to cover the board on which the analysis chip is provided, the mold comprising an opening above the liquid receiver, a first shield layer provided on a back surface of the board, and a second shield layer provided to be attachable and detachable on an opposite side to the analysis chip of the mold, the second shield layer being electrically connected to a part of the electrical terminal.Type: GrantFiled: September 8, 2015Date of Patent: September 26, 2017Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Hiroshi Hamasaki, Michihiko Nishigaki, Yutaka Onozuka, Kentaro Kobayashi, Hiroko Miki, Naofumi Nakamura
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Publication number: 20170122859Abstract: According to one embodiment, a particle inspection system includes a voltage driving circuit which applies a driving voltage for a particle inspection to a particle inspection chip, a current-voltage conversion circuit which converts, into a voltage signal, a current signal output from the particle inspection chip when the driving voltage is applied to the particle inspection chip, a detection circuit which detects, based on the voltage signal, whether the sample liquid is introduced into a detection region of the particle inspection chip, and an analysis circuit which analyzes the fine particle, in the sample liquid based on the voltage signal. The voltage driving circuit varies the driving voltage based on the detection result of the detection circuit.Type: ApplicationFiled: January 18, 2017Publication date: May 4, 2017Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Michihiko NISHIGAKI, Hiroshi HAMASAKI, Naofumi NAKAMURA, Kentaro KOBAYASHI, Hiroko MIKI