Patents by Inventor Min Ding
Min Ding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12568879Abstract: The disclosure provides a work vehicle. The work vehicle includes: a frame, a wheel unit connected with the frame, a working unit connected with the frame, and a power source arranged on the frame to supply power. The work vehicle further includes: a brake assembly connected with the wheel unit, a locking assembly, provided with a lock arm to lock the brake assembly, and a starting mechanism. The starting mechanism includes a starting arm connected with the lock arm to drive the lock arm to move when the starting arm is operated to unlock the brake assembly.Type: GrantFiled: December 21, 2021Date of Patent: March 10, 2026Assignee: Globe (Jiangsu) Co., Ltd.Inventors: Min Ding, Qunli Wei, Fei Zhu, Chaoqun Wang
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Patent number: 12394911Abstract: Anti-reflective assemblies comprise: a high dielectric permittivity substrate comprising a ceramic and a nonporous multilayer anti-reflective film contacting or adhesively bonded to the substrate. The nonporous multilayer anti-reflective film comprises sequential first, second, and third layers of sequentially decreasing dielectric permittivity. Each layer comprises a respective polymer matrix and filler particles.Type: GrantFiled: March 4, 2022Date of Patent: August 19, 2025Assignee: 3M Innovative Properties CompanyInventors: Dipankar Ghosh, Weigang Lin, Jie Huang, Min Ding, Wei Li, Kun Wang
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Publication number: 20250221336Abstract: A mower includes a frame, a walking assembly, a cutting deck assembly and an operating mechanism. The walking assembly, the cutting deck assembly and the operating mechanism are all installed on the frame, and the operating mechanism is configured to control a walking of the walking assembly. The operating mechanism includes an operating lever mounting base, an operating lever, a limiting assembly and a reset assembly. The operating lever mounting base is rotatably installed on the frame along a first direction. The operating lever is rotatably installed on the operating lever mounting base along a second direction. The reset assembly drives the operating lever to reset to an initial position in the first direction, and the limiting assembly locks the operating lever in the initial position.Type: ApplicationFiled: March 17, 2025Publication date: July 10, 2025Inventors: Qunli Wei, Dongdong Shi, Qinghua Shi, Chris Eichel, Chenghai Ning, Yansheng Sun, Min Ding, Qin Ji, Nick Suchoza, Hui Chen, Jing Wang, Jiafu Xue, Paulius Bulovas, Jaquline Hultman, Tao Yu, Xiazi Li, Tao Wang, Naixin Gao, Zhiyuan Li, Yu Mei, Fei Zhu, Shiyuan Ding, Yueyue Xu
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Publication number: 20250213540Abstract: A composition having clevidipine as an active ingredient is described. The composition includes clevidipine as an active ingredient and an amount of the impurity H168/79 that is no greater than about 1.5%, or where the ratio between clevidipine and H168/79 is equal or above 60 to 1.Type: ApplicationFiled: September 16, 2024Publication date: July 3, 2025Applicants: CHIESI FARMACEUTICI S.P.A., HOSPIRA, INC.Inventors: Rajeshwar MOTHERAM, Gopal KRISHNA, Min DING, Keith FLOOD, Kornepati RAMAKRISHNA
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Publication number: 20250204311Abstract: A mower includes a frame, a cutting deck assembly and a walking mechanism. The cutting deck assembly is mounted on the frame. The walking mechanism is mounted on the frame and includes a front wheel assembly and a rear wheel assembly. The frame includes a front frame and a rear frame. The front frame is detachably connected with the rear frame. The front frame is provided with the front wheel assembly, and the rear frame is provided with the rear wheel assembly. When the cutting deck assembly needs to be replaced to meet use requirements, the front frame and the rear frame of appropriate specifications are first selected to be fixed to ensure that the cutting deck assembly has a suitable mounting size, so that the suitable cutting deck assembly may be replaced in different working environments to meet the use requirements of a variety of environments.Type: ApplicationFiled: March 15, 2025Publication date: June 26, 2025Inventors: Qunli Wei, Dongdong Shi, Qinghua Shi, Chris Eichel, Chenghai Ning, Yansheng Sun, Nick Suchoza, Hui Chen, Jing Wang, Jiafu Xue, Paulius Bulovas, Jaquline Hultman, Tao Yu, Min Ding, Yu Mei, Fei Zhu, Shiyuan Ding, Yueyue Xu, Xiazi Li, Tao Wang, Naixin Gao, Zhiyuan Li
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Patent number: 12234481Abstract: Use of an exosome derived from decidual natural killer (dNK) cells or a dNK cell subset in the preparation of a drug and an auxiliary therapeutic agent for infertility-related diseases is provided. Experiments have confirmed that the exosome treats the endometrial growth disorder-related diseases by promoting increase of endometrial thickness, increasing endometrial cell viability, reducing endometrial cell damage, promoting VEGF expression, and maintaining stemness and stimulating proliferation of endometrial stromal cells, such that a conception rate for endometrial injury model mice increases from 20% to 50%-70%; and the exosome treats the maternal-fetal immune tolerance disorder-related diseases by exerting immune tolerance, reducing a spontaneous abortion rate, and increasing a helper T cell level.Type: GrantFiled: September 30, 2020Date of Patent: February 25, 2025Assignee: PHARCHOICE THERAPEUTICS INCInventors: Shi Hu, Min Ding
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Publication number: 20240162624Abstract: Anti-reflective assemblies comprise: a high dielectric permittivity substrate comprising a ceramic and a nonporous multilayer anti-reflective film contacting or adhesively bonded to the substrate. The nonporous multilayer anti-reflective film comprises sequential first, second, and third layers of sequentially decreasing dielectric permittivity. Each layer comprises a respective polymer matrix and filler particles.Type: ApplicationFiled: March 4, 2022Publication date: May 16, 2024Inventors: Dipankar Ghosh, Weigang Lin, Jie Huang, Min Ding, Wei Li, Kun Wang
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Patent number: 11964973Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR6 or N; Y is CR3 or N; R1, R2, R3, R4, R5, R6, R7, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: GrantFiled: December 22, 2020Date of Patent: April 23, 2024Assignee: Bristol-Myers Squibb CompanyInventors: Robert G. Gentles, Upender Velaparthi, Min Ding, Richard E. Olson, Scott W. Martin, Saumya Roy, Prasada Rao Jalagam, Jayakumar Sankara Warrier, Louis S. Chupak, Denise Christine Grunenfelder
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Publication number: 20240099196Abstract: The disclosure provides a mower. The mower includes a vehicle frame, a walking assembly, a working assembly, a seat and a battery pack. The walking assembly includes a first walking wheel assembly and a second walking wheel assembly connected with the vehicle frame. The first walking wheel assembly and/or the second walking wheel assembly includes a main walking wheel and a hub motor, the main walking wheel is connected with the hub motor, and the hub motor is arranged outside a side of the vehicle frame. The working assembly is connected with the vehicle frame. The seat is arranged on the vehicle frame. The battery pack is lowered and mounted on the vehicle frame and extends below the seat.Type: ApplicationFiled: December 11, 2023Publication date: March 28, 2024Applicant: Greenworks (Jiangsu) Co., Ltd.Inventors: Qunli WEI, Dongdong SHI, Chen ZHU, Min DING, Chaoqun WANG, Fei ZHU, Jun FAN, Liang PENG
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Patent number: 11866430Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, and R4 are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK ?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: GrantFiled: June 26, 2019Date of Patent: January 9, 2024Assignee: Bristol-Myers Squibb CompanyInventors: Louis S. Chupak, Min Ding, Robert G. Gentles, Yazhong Huang, Scott W. Martin, Ivar M. Mcdonald, Stephen E. Mercer, Richard E. Olson, Upender Velaparthi, Michael Wichroski, Xiaofan Zheng
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Publication number: 20230302002Abstract: Pharmaceutical compositions, and a method of stabilizing pharmaceutical compositions having clevidipine, or any pharmaceutically acceptable salt thereof, as the active ingredient is described. The method includes the slowing down or inhibiting of the oxidation pathway of clevidipine. This can be accomplished by reducing the amount the pharmaceutical composition is exposed to oxygen and/or light during the manufacturing and storing processes. According to this method, oxygen must be removed or replaced, or light must be sufficiently blocked such that light energy cannot reach the active ingredient of the composition, or is reduced to a level that the light-induced oxidation reaction converting clevidipine to H324/78 is minimized, such that the total detectable level of H324/78 in a given composition sample does not exceed about 0.2% on a weight-by-weight basis, or the ratio of clevidipine to H324/78 is equal to or greater than about 450 to 1 on a weight-to-weight basis.Type: ApplicationFiled: May 30, 2023Publication date: September 28, 2023Applicant: Chisei Farmaceutici S.p.A.Inventors: Gopal KRISHNA, Rajeshwar MOTHERAM, Min Ding
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Patent number: 11713316Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: GrantFiled: February 1, 2021Date of Patent: August 1, 2023Assignee: Bristol-Myers Squibb CompanyInventors: Upender Velaparthi, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
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Publication number: 20230089255Abstract: Provided are inhibitors of diacylglycerol kinases (DGK) and methods for treating diseases that would benefit from the stimulation of the immune system, such as cancer and infections diseases, comprising administering a DGK inhibitor in combination with an antagonist of the PD 1/PD-L 1 axis and/or an antagonist of CTLA4.Type: ApplicationFiled: December 18, 2020Publication date: March 23, 2023Inventors: Susan WEE, Joseph L. BENC, Xinyu WANG, Upender VELAPARTHI, Louis S. CHUPAK, Chatan P. DARNE, Min DING, Robert G. GENTLES, Yazhong HUANG, Scott W. MARTIN, Ivar M. MCDONALD, Richard E. OLSON, Xiaofan ZHENG, John S. TOKARSKI, Bireshwar DASGUPTA, Manjunatha Narayana Rao KAMBLE, Raju MANNOORI, Haslbur RAHAMAN, Prasada Rao JALAGAM, Saumya ROY, Gopikishan TONUKUNURU, Sivasudar VELAIAH, Jayakumar Sankara WARRIER, Kotha Rathnakar REDDY, Thiruvenkadam RAJA, Denise GRUNENFELDER, Michael WICHROSKI
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Publication number: 20230061608Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein: R1, R2, R3, R4, R5, R6, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: ApplicationFiled: December 22, 2020Publication date: March 2, 2023Inventors: Louis S. Chupak, Richard E. Olson, Upender Velaparthi, Xiaofan Zheng, Robert G. Gentles, Min Ding, Jayakumar Sankara Warrier
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Publication number: 20220324859Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: ApplicationFiled: February 1, 2021Publication date: October 13, 2022Inventors: Upender Velaparthi, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
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Publication number: 20220275048Abstract: A soluble dimeric immunoadhesin includes a dimerized first polypeptide chain and a dimerized second polypeptide chain. The first polypeptide chain has a general formula of Z1-Z2, and the second polypeptide chain has a general formula of Y1-Y2. Z1 is (i) an extracellular domain of a first cell surface receptor or a functional variant or fragment thereof, or (ii) a first cytokine or a functional variant or fragment thereof; Z2 is a dimerization domain of an immunoglobulin constant region or a functional variant or fragment thereof. Y1 is an extracellular domain of a second cell surface receptor or a functional variant or fragment thereof, or (ii) a second cytokine or a functional variant or fragment thereof. Y2 is a dimerization domain of an immunoglobulin constant region or a functional variant or fragment thereof. A dimeric protein can be used for the treatment and prevention of infertility-related diseases.Type: ApplicationFiled: March 17, 2022Publication date: September 1, 2022Applicant: PHARCHOICE THERAPEUTICS INCInventors: Shi HU, Min DING
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Publication number: 20220201931Abstract: The disclosure provides a work vehicle. The work vehicle includes: a frame, a wheel unit connected with the frame, a working unit connected with the frame, and a power source arranged on the frame to supply power. The work vehicle further includes: a brake assembly connected with the wheel unit, a locking assembly, provided with a lock arm to lock the brake assembly, and a starting mechanism. The starting mechanism includes a starting arm connected with the lock arm to drive the lock arm to move when the starting arm is operated to unlock the brake assembly.Type: ApplicationFiled: December 21, 2021Publication date: June 30, 2022Applicant: Globe (Jiangsu) Co., Ltd.Inventors: Min Ding, Qunli Wei, Fei Zhu, Chaoqun Wang
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Publication number: 20220096550Abstract: Use of an exosome derived from decidual natural killer (dNK) cells or a dNK cell subset in the preparation of a drug and an auxiliary therapeutic agent for infertility-related diseases is provided. Experiments have confirmed that the exosome treats the endometrial growth disorder-related diseases by promoting increase of endometrial thickness, increasing endometrial cell viability, reducing endometrial cell damage, promoting VEGF expression, and maintaining stemness and stimulating proliferation of endometrial stromal cells, such that a conception rate for endometrial injury model mice increases from 20% to 50%-70%; and the exosome treats the maternal-fetal immune tolerance disorder-related diseases by exerting immune tolerance, reducing a spontaneous abortion rate, and increasing a helper T cell level.Type: ApplicationFiled: September 30, 2020Publication date: March 31, 2022Applicant: PHARCHOICE THERAPEUTICS INCInventors: Shi HU, Min DING
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Publication number: 20220000849Abstract: A composition having clevidipine as an active ingredient is described. The composition includes clevidipine as an active ingredient and an amount of the impurity H168/79 that is no greater than about 1.5%, or where the ratio between clevidipine and H168/79 is equal or above 60 to 1.Type: ApplicationFiled: June 16, 2021Publication date: January 6, 2022Applicants: Chiesi Farmaceutici S.p.A., HOSPIRA, INC.Inventors: Rajeshwar MOTHERAM, Gopal KRISHNA, Min DING, Keith FLOOD, Kornepati RAMAKRISHNA
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Publication number: 20210277004Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, and R4 are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK ?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: ApplicationFiled: June 26, 2019Publication date: September 9, 2021Inventors: Louis S. Chupak, Min Ding, Robert G. Gentles, Yazhong Huang, Scott W. Martin, Ivar M. Mcdonald, Stephen E. Mercer, Richard E. Olson, Upender Velaparthi, Michael Wichroski, Xiaofan Zheng