Abstract: The present invention relates to a system for predicting prognosis and benefit from adjuvant chemotherapy for patients with stage II and III gastric cancer, and an algorithm that can predict prognosis and chemotherapy responsiveness using quantitative analysis results of mRNA expression levels of a prognosis or chemotherapy responsiveness-related marker gene group and a reference gene group in advanced gastric cancer is developed, and can be used as supplementary information to determine a method for treating a gastric cancer patient.

Abstract: The disclosure describes a method in an electronic device. The electronic device comprises a memory, a communication unit, and a processor configured to control the communication unit to establish a network connection with a server after storing a image file in the memory, control the communication unit to transmit a image file to the server from the electronic device after establishing the network connection with the server, obtain a link information for downloading the image file from the server after establishing the network connection with the server, and after establishing the network connection with the server, replace the image file with a lower resolution image corresponding to the image file in the memory based at least on a memory capacity available in the memory.

Abstract: The present invention relates to a group classification and prognosis prediction system based on the biological characteristics of gastric cancer, and an algorithm capable of predicting the prognosis of advanced gastric cancer in terms of overall survival by using a quantified value of an mRNA expression level of a target gene group has been developed and this may be used as auxiliary information for determining a treatment method of a gastric cancer patient.

Abstract: A method is disclosed, which comprises forming a mid layer over a mask stack that is over a device layer of a substrate; forming a first buffer layer on the mid layer and a plurality pairs of first linear patterns over the first buffer layer; deposing a spin on hard mask layer filling between the first linear patterns; forming a second buffer layer on the spin on hard mask layer and a plurality of second linear patterns on the second buffer layer that projectively intercepts the first linear patterns; performing a mid layer opening process by concurrently etching the second buffer layer, the spin on hard mask layer, and the first buffer layer through the first and the second linear patterns to partially expose the mid layer; and etching the exposed portions of the mid layer to form a grid-type pattern over the mask stack.

Abstract: A method is disclosed, which comprises forming a mid layer over a mask stack that is over a device layer of a substrate; forming a first buffer layer on the mid layer and a plurality pairs of first linear patterns over the first buffer layer; deposing a spin on hard mask layer filling between the first linear patterns; forming a second buffer layer on the spin on hard mask layer and a plurality of second linear patterns on the second buffer layer that projectively intercepts the first linear patterns; performing a mid layer opening process by concurrently etching the second buffer layer, the spin on hard mask layer, and the first buffer layer through the first and the second linear patterns to partially expose the mid layer; and etching the exposed portions of the mid layer to form a grid-type pattern over the mask stack.

Abstract: A semiconductor device includes a substrate, a first lower wiring line on the substrate, a first insulation layer on the first lower wiring line, a first dielectric barrier layer and a first etch stop layer sequentially stacked on the first insulation layer, a second insulation layer on the first etch stop layer, a first upper wiring line extending through the second insulation layer, the first etch stop layer, and the first dielectric barrier layer, and a first conductive via in the first insulation layer and electrically connecting the first lower wiring line and the first upper wiring line. An upper surface of the first conductive via protrudes above a lower surface of the first upper wiring line.

Abstract: A method in an electronic device is provided, the method including: connecting to a storage device; transmitting a first file to the storage device; when the first file is transmitted to the storage device, generating, a second file based on the first file and replacing the first file with the second file, wherein the second file is an optimized version of the first file.

Abstract: A method and an apparatus for diagnosing a brain tumor in real-time are disclosed. A method for detecting a brain tumor in real-time can comprise the steps of: generating, by a probe, a plurality of input signals and transferring the same to a target detection region which is estimated to be the location of a brain tumor; receiving, by the probe, a plurality of reflection signals on the basis of a plurality of input signals; and detecting, by the probe, a plurality of the received reflection signals, wherein a plurality of the input signals comprise a terahertz signal, an optical coherence tomography (OCT) signal, and a Raman signal, and a plurality of the reflection signals can be used for generating a plurality of image information for detecting the location of a brain tumor; and an apparatus for diagnosing a brain tumor in vitro and in real-time, can be used to diagnose, in real-time, a brain tumor specimen, which is extracted from the brain.

Abstract: A semiconductor device includes a substrate, a first lower wiring line on the substrate, a first insulation layer on the first lower wiring line, a first dielectric barrier layer and a first etch stop layer sequentially stacked on the first insulation layer, a second insulation layer on the first etch stop layer, a first upper wiring line extending through the second insulation layer, the first etch stop layer, and the first dielectric barrier layer, and a first conductive via in the first insulation layer and electrically connecting the first lower wiring line and the first upper wiring line. An upper surface of the first conductive via protrudes above a lower surface of the first upper wiring line.

Abstract: A bioenvironment-sensitive nanoparticle including a polymer having complementary charges, a method of manufacturing the same, and a pharmaceutical use of the bioenvironment-sensitive nanoparticle are disclosed. The bioenvironment-sensitive nanoparticle can be useful in stably and effectively delivering a target material such as a drug even when used at a small quantity since the nanoparticle is stable in extracellular environments. Also, the bioenvironment-sensitive nanoparticle can be useful in selectively diagnosing or treating cancer cells since the nanoparticle is specific to environments of the cancer cells.

Abstract: The present invention relates to a system for predicting prognosis and benefit from adjuvant chemotherapy for patients with stage II and III gastric cancer, and an algorithm that can predict prognosis and chemotherapy responsiveness using quantitative analysis results of mRNA expression levels of a prognosis or chemotherapy responsiveness-related marker gene group and a reference gene group in advanced gastric cancer is developed, and can be used as supplementary information to determine a method for treating a gastric cancer patient.

Abstract: The present invention relates to a group classification and prognosis prediction system based on the biological characteristics of gastric cancer, and an algorithm capable of predicting the prognosis of advanced gastric cancer in terms of overall survival by using a quantified value of an mRNA expression level of a target gene group has been developed and this may be used as auxiliary information for determining a treatment method of a gastric cancer patient.

Abstract: Provided are polyaniline coordinated with a transition metal, a core-shell nanoparticle including the same as a core, and preparation methods thereof. According to the polyaniline coordinated with a transition metal and the nanoparticle of the present application, it is possible to prepare polyaniline coordinated with a transition metal using an oxidizing agent having a core-shell structure and including the transition metal and a nanoparticle including the same as a core. The polyaniline prepared as such is in a doped state, and, thus, a preparation process is simple. Further, dispersibility with respect to a solvent is improved, and a band gap level of the polyaniline can be easily regulated.

Abstract: A method and an apparatus for diagnosing a brain tumor in real-time are disclosed. A method for detecting a brain tumor in real-time can comprise the steps of: generating, by a probe, a plurality of input signals and transferring the same to a target detection region which is estimated to be the location of a brain tumor; receiving, by the probe, a plurality of reflection signals on the basis of a plurality of input signals; and detecting, by the probe, a plurality of the received reflection signals, wherein a plurality of the input signals comprise a terahertz signal, an optical coherence tomography (OCT) signal, and a Raman signal, and a plurality of the reflection signals can be used for generating a plurality of image information for detecting the location of a brain tumor; and an apparatus for diagnosing a brain tumor in vitro and in real-time, can be used to diagnose, in real-time, a brain tumor specimen, which is extracted from the brain.

Abstract: A preparation method for a magnetic composite for treating and diagnosing cancer. The method may include a step of pyrolyzing a precursor of a magnetic nanoparticle in the presence of a conjugated polymer. The preparation method for a magnetic composite can produce a magnetic composite economically and efficiently because a magnetic composite comprising a magnetic nanoparticle coated with a conjugated polymer can be prepared by a single process.

Abstract: A method in an electronic device is provided, the method including: connecting to a storage device; transmitting a first file to the storage device; when the first file is transmitted to the storage device, generating, a second file based on the first file and replacing the first file with the second file, wherein the second file is an optimized version of the first file.

Abstract: The present invention relates to an amphiphilic nanoparticle specific to a biomarker, and more particularly, provides an amphiphilic nanoparticle which may be used as a diagnosis or treatment-type drug or gene carrier by selectively recognizing a proteolytic enzyme specifically expressed in a cellular membrane of a specific cell, and then being bound to the proteolytic enzyme to efficiently achieve the intracellular uptake and selective cleavage. The amphiphilic nanoparticle of the present invention may be used in the diagnosis or therapy of a disease.

Abstract: The present invention relates to an amphiphilic nanoparticle specific to a biomarker, and more particularly, provides an amphiphilic nanoparticle which may be used as a diagnosis or treatment-type drug or gene carrier by selectively recognizing a proteolytic enzyme specifically expressed in a cellular membrane of a specific cell, and then being bound to the proteolytic enzyme to efficiently achieve the intracellular uptake and selective cleavage. The amphiphilic nanoparticle of the present invention may be used in the diagnosis or therapy of a disease.

Abstract: A preparation method for a magnetic composite for treating and diagnosing cancer. The method may include a step of pyrolyzing a precursor of a magnetic nanoparticle in the presence of a conjugated polymer. The preparation method for a magnetic composite can produce a magnetic composite economically and efficiently because a magnetic composite comprising a magnetic nanoparticle coated with a conjugated polymer can be prepared by a single process.

Abstract: The present invention relates to a system and a method for providing a data analysis service in a cloud environment which does not need to transmit data to an analysis section from a file storage section when providing an analysis service about big data. According to the present invention, it is not needed to specifically move files when analyzing big data, by using the storage section resource in a virtual machine in a cloud environment as storages, and accordingly, the analysis time can be considerably reduced.