Abstract: One aspect of the disclosure relates to a cargo delivery system comprising an autophagy targeting ligand and a target-binding ligand. In one aspect of the disclosure, by comprising an autophagy targeting ligand, cargo, which is a target-binding ligand that specifically binds to a target, is delivered to the p62 protein and autophagy is activated, so that depending on the type of target-binding ligand used, a target to be degraded can be selectively and directly removed. Accordingly, the cargo delivery system according to an aspect of the disclosure may be used in pharmaceutical compositions or food compositions for preventing, alimerating, and treating various diseases.

Abstract: There is provided a method for matching a public technology with a technology consumer, the method being performed by a computing system. The method may comprise acquiring data about the public technology, applying the acquired data to a first machine-learning model to acquire technology feature data about the public technology, wherein the first machine-learning model is configured to output the technology feature data based on the data about the public technology and matching the public technology with at least one technology consumer, based on the technology feature data and a plurality of consumer feature data stored in a database.

Abstract: Disclosed are a communication protocol conversion method and apparatus for detecting communication protocol conversion errors between heterogeneous automobile communication networks. The communication protocol conversion method includes: storing a copy of a first communication network frame received, converting the received first communication network frame into a second communication network frame through a first conversion module, inversely converting the converted second communication network frame into a first communication network frame through a second conversion module, comparing the stored copy of the first communication network frame and the inversely converted first communication network frame, and detecting conversion errors between the first and second communication network frames according to a comparison result.

Abstract: A lobamide compound according to an embodiment of the present disclosure is represented by Formula 1. The lobamide compound has excellent PTP-1B inhibitory activity that is far higher than that of conventional lobaric acid derivatives and which can be orally administered, and thus is very effective in the prevention or treatment of diabetes or obesity through oral administration.

Abstract: The present invention relates to a multi-path converter, which adds a current transfer path using a capacitor to a current transfer path using an inductor to supply a current that is output to an output end (load) to a plurality of parallel paths, thereby reducing a total RMS current flowing through the inductor, and a control method therefor.

Abstract: Etching compositions are provided. The etching compositions can be used for etching cobalt. The etching compositions may include a chelator, water, an oxidizer, and an organic solvent, and the chelator may include an organic acid, an amine compound and/or a polyhydric alcohol. Water may be present in an amount of 1 wt % to 10 wt % based on a total weight of the etching composition.

Abstract: A mask assembly includes: a mask frame; a mask supported by the mask frame, the mask including a plurality of pattern holes; and a magnetic part disposed on one surface of the mask. The magnetic part provides a magnetic force between the mask and a target substrate and improves an adhesion between the mask and the target substrate to prevent deposition defects.

Abstract: A selective catalytic reduction (SCR) system, comprising a box body, a mixer, a baffle and a carrier, the mixer, the baffle and the carrier being sequentially arranged inside the box body in an airflow direction inside the box body, the baffle being provided with a plurality of through holes, and the distribution density of the through holes and/or the hole area of the through holes being negatively correlated with a distribution uniformity index of NH3 at the baffle. The configuration of the distribution density and the hole area of the through holes can improve the mixing uniformity of ammonia gas, so that a reaction effect of a catalyst and a mixed gas in the carrier is enhanced. The settings of the distribution density and the hole area of the through holes can improve the mixing uniformity of an ammonia gas.

Abstract: An eco-friendly quarantine composition has a function of killing phospholipid enveloped viruses, The eco-friendly quarantine composition includes: 10 to 40 wt. % of polyoxyethylene lauryl ether, 0.01 to 10 wt. % of polyoxyethylene 2-ethylhexyl ether, 0.01 to 10 wt. % of polyoxyethylene polyoxypropylene alkyl ether, and a balance of solvent, based on the total 100 wt. % of the composition. The eco-friendly quarantine composition may have 100% of SARS-CoV-2 virus removal rate in 1 minute and an effect of killing 100% of highly pathogenic avian influenza virus in 1 to 10 minutes. The composition has low cytotoxicity such that IC50 value (%) for human epithelial keratinocyte cells (HaCaT), human bronchial epithelial cells (BEAS-2B), and human monocyte cells (THP-1) is in a range of 0.003 to 0.0045, and effects of having antibacterial activity against non-pathogenic strains, and pathogenic strains.

Abstract: The present invention relates to a composition for improving memory, improving cognition, preventing or treating cerebral neurological disease, comprising porcine brain enzyme hydrolysate. The composition can exhibit neuroprotective activity, brain-derived neurotrophic factor (BDNF) production activity, acetylcholinesterase inhibitory activity and reactive oxygen species (ROS) inhibitory activity.

Abstract: The present invention relates to a composition for promoting myogenesis, containing, as an active ingredient, a processed ginseng extract in which a trace amount of a ginsenoside ingredient is increased. It has been ascertained that the processed ginseng extract promotes the differentiation of myoblasts into muscle and inhibits muscle atrophy caused by myostatin, which is a myogenesis inhibitory factor, and thus it is expected that a composition for preventing or treating muscle disorder-related diseases, having excellent effects, can be developed.

Abstract: The present invention relates to a nanosuspension formulation suitable for a progerinin drug, which is insoluble, and a preparation method therefor, wherein the progerinin nanosuspension is a vehicle composition for improving dispersive stability of a progerinin drug(a), which is insoluble, and employs hydroxypropylmethyl cellulose (HPMC)(b) or hydroxypropyl cellulose (HPC)(b?), TPGS(c) or sodium dioctyl succinate (DOSS)(c?), and potassium sorbate(d), and a mixture thereof was subjected to wet-type ball milling in a Dyno-Mill chamber to prepare a white nanosuspension containing a progerinin drug with an average particle diameter of 100 nm to 300 nm.

Abstract: Provided is an integrated optical system-based optical current sensor system comprising a light source generating reference light for current or magnetic field sensing, a polarizer for polarizing the reference light, a phase modulator for phase-modulating the polarized light into a predetermined reference signal, and a Faraday rotation reflector for reflecting the light propagated through an optical path at the end of the optical fiber, wherein the invention further comprises a plurality of pig-tailed optical fiber blocks in which the optical fibers are accommodated therein, and an integrated optical system composed of a plurality of optical components optically bonded to the pig-tailed blocks at interfaces with the pig-tailed blocks.

Abstract: Provided is a special optical fiber for measuring a 3D curved shape, and a system for measuring the 3D curved shape by using a special optical fiber. The special optical fiber comprises: an optical fiber core for transmitting an optical signal; an inner cladding covering the optical fiber core; and an outer cladding covering the inner cladding. In particular, the refractive index (n1) of the optical fiber core, the refractive index (n2) of the inner cladding, and the refractive index (n3) of the outer cladding are set in a relationship of n1?n3>n2. The inner cladding covering the optical fiber core has a cut portion in the longitudinal direction. The optical fiber core is exposed through the cut portion. In addition, the cut portion is filled with a material having the same refractive index as the optical fiber core or the outer cladding.

Abstract: Provided is an optical detection device for sensing environmental changes inside and outside a fiber optic sensor probe by detecting polarization and optical power differences between a plurality of input signals, the optical detection device being characterized by comprising: a plurality of optical fiber pigtail blocks internally accommodated with a portion of the optical fibers; an integrated optical system composed of a plurality of optical components optically bonded to the optical fiber pigtail blocks at interfaces with the bulk optical components; and a balanced optical detection component for comparing components of a plurality of polarized lights received from the integrated optical system.

Abstract: The present invention relates to a method for producing botulinum toxin in various fragments to then be reassembled, for safely producing same. In the present invention, devised is a method in which: botulinum toxin is produced in fragments by cleaving light and heavy chains thereof into two or three pieces, respectively, and then combined as a full-length toxin, thereby allowing high complexity in production, due to toxicity, as well as low safety and economic feasibility, to be overcome; production of water-soluble botulinum toxin is enabled by using bacteria, thereby markedly shortening the production time as compared to existing production methods; and conjugation of the produced fragments with other proteins and nanoparticles is also enabled, thereby increasing the pharmaceutical extensibility of the toxin.

Abstract: The present disclosure relates to an organic compound having the following structure, and an organic light emitting diode (OLED) and an organic light emitting device including the organic compound. The organic compound can be a bipolar compound having a p-type moiety and an n-type moiety and has high energy level and proper energy bandgap for an emissive layer of the OLED. As the organic compound is applied into the emissive layer, the OLED can maximize its luminous properties as holes and electrons are recombined uniformly over the whole area in an emitting material layer (EML).

Abstract: An electroluminescent display apparatus can include a display panel including a first active region configured to display first image data and a second active region configured to display second image data. The apparatus can further include a first memory configured to store a first main compensation value and a first boundary compensation value, corresponding to first pixels in the first active region, and a second memory configured to store a second main compensation value and a second boundary compensation value, corresponding to second pixels in the second active region. The apparatus can further include a first timing controller configured to correct the first image data based on the first main compensation value and the first and second boundary compensation values, and a second timing controller configured to correct the second image data based on the second main compensation value, the second boundary compensation value, and the first boundary compensation value.

Abstract: The present invention relates to a method for preparing a fuel cell catalyst electrode, which includes dispersing and mixing a first catalyst, a binder, and a first solvent to prepare a first catalyst slurry, heat-treating and pulverizing the first catalyst slurry to prepare a first catalyst powder, dispersing and mixing a second catalyst, a binder, and a second solvent to prepare a second catalyst slurry, heat-treating and pulverizing the second catalyst slurry to prepare a second catalyst powder, dispersing the first catalyst powder and the second catalyst powder in a third solvent to prepare a third catalyst slurry, and applying or transferring the third catalyst slurry onto a substrate to prepare an electrode having a catalyst layer formed therein.