Abstract: Provided is a method of screening a target-specific antibody for an antigen that undergoes structural change in a particular physiological condition.

Abstract: A bispecific antigen binding protein complex comprising a first polypeptide comprising a first antigen binding site at an N terminus; a second polypeptide comprising a second antigen binding site at an N terminus; and a linker connecting the first polypeptide and the second polypeptide; wherein the linker comprises a tag at one terminus thereof, and wherein the tag is connected to a C-terminus of the first polypeptide or to an N-terminus of the second polypeptide, and comprises a cleavable amino acid sequence; as well as related compositions and methods.

Abstract: Provided is a protein complex including a bi-specific antibody, and a method of preparing the protein complex, which can provide a system that simultaneously targets two antigens.

Abstract: A protein complex comprising (i) a first fusion protein comprising (a) a first polypeptide that comprises a first antigen-binding site and (b) a first binding protein linked to a terminus of the first polypeptide; and (ii) a second fusion protein comprising (a) a second polypeptide that comprises a second antigen-binding site and (b) a second binding protein linked to a terminus of the second polypeptide, wherein the protein complex comprises an amino acid sequence that enables cleavage between the first polypeptide and the first binding protein, and/or between the second polypeptide and the second binding protein, as well as a method for preparing a bi-specific antibody and related methods and compositions.

Abstract: A polypeptide inhibiting binding between vascular endothelial growth factor receptor-2 and a vascular endothelial growth factor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Abstract: An antibody specifically binding to angiopoietin-2, and antigen-binding fragments thereof, and a use thereof are disclosed.

Abstract: Disclosed herein is an apparatus and method for managing images based on user preferences. The apparatus includes a database for storing images, an image search module for searching the images stored in the database, an image output module for outputting at least one image retrieved by the image search module, a preference input module for, when the retrieved image is output through the image output module, receiving a user preference for the output image from a user, and an image path database for storing a storage path of the image, output through the image output module, based on the user preference received through the user preference input module. The image search module searches images whose storage paths are stored in the image path database or images whose storage paths are not stored in the image path database according to the user's selection.

Abstract: A polypeptide inhibiting binding between a vascular endothelial growth factor and a vascular endothelial growth factor receptor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Abstract: A method and apparatus for multimedia content playback are disclosed. Upon detecting user entry of a content selection command, the apparatus randomly selects a number of multimedia content items from an entire list of stored multimedia content. A playlist is created containing the selected multimedia content items as entries, and the playlist is displayed. At least one multimedia content item on the playlist is played back upon reception of a playback command for the playlist.

Abstract: A polypeptide inhibiting binding between a vascular endothelial growth factor and a vascular endothelial growth factor receptor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Abstract: An apparatus and method for compensating for the picture quality of a stored broadcast signal are disclosed. For reproduction of a broadcast signal stored in a television, the picture quality of the stored broadcast signal is compensated for, based on a predetermined. MPEG noise reduction value corresponding to the electric field strength of the stored broadcast signal. Therefore, it is possible to provide the optimum picture quality. When a broadcast signal is stored, it is stored together with the electric field strength, thereof. When the stored broadcast signal is reproduced, block noise, of a screen is efficiently removed by applying an MPEG, noise reduction value corresponding to the electric field strength of the stored broadcast signal to the stored broadcast signal. Therefore it is possible to improve the definition of the screen.

Abstract: A polypeptide inhibiting binding between a vascular endothelial growth factor and a vascular endothelial growth factor receptor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Abstract: The present invention relates to a cosmetic composition comprising: (i) boron nitride; and (ii) one or more kinds of inorganic powders selected from the group consisting of cerium oxide, titanium oxide, talc, aluminum oxide, iron oxide, zinc oxide and mica. UVA, UVB and near-IR may be simultaneously screened by applying the cosmetic composition.

Abstract: A method for providing a Graphic User Interface (GUI) associated with execution of an application in a mobile terminal supporting a multi-tasking function, and an apparatus implementing the same. The method for providing (GUI) in a mobile terminal, preferably includes: displaying an application execution icon region and application execution screen region configured by one or more application execution icons; receiving selection of one from the one or more application execution icons; and displaying a reduction mode execution screen of an application corresponding to the selected application execution icon on the application execution screen region. When using a multi-tasking function of a mobile terminal, the user can view a plurality of application execution screens on one screen, and input an operating command for a plurality of applications on one screen.

Abstract: A method and an apparatus for playing contents are provided. The apparatus includes: a touch screen playing contents on a screen and detecting a touch input through the screen; and a processor sensing a touch event occurring on the touch screen during a playback of the contents, displaying a progressive bar having information regarding running time of the contents played on the touch screen to overlap with the contents in response to the touch event, and controlling display of a mark at a location of the progressive bar corresponding to an occurrence time point of the touch event.

Abstract: A portable terminal to provide social network service using human body communication includes a human body communication unit to transmit or receive data through a human body, a memory unit to store at least one of social data, user data, reference data, and any additional data collected, a contact object identifying unit to identify a contact object by using the data received by the human body communication unit, and a pattern analyzing unit to analyze a pattern of contact with the contact object using the data stored in the memory unit. A method for providing social network service using human body communication includes sensing a human body contact, identifying a contact object, and analyzing a pattern of contact with the contact object using at least one of social data, user data, reference data and any additional data collected.

Abstract: A polypeptide inhibiting binding between a vascular endothelial growth factor and a vascular endothelial growth factor receptor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Abstract: A polypeptide inhibiting binding between vascular endothelial growth factor receptor-2 and a vascular endothelial growth factor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Abstract: An antibody specifically binding to angiopoietin-2, and antigen-binding fragments thereof, and a use thereof are disclosed.

Abstract: The present invention relates to the system, method and program for the pharmacokinetic parameter prediction of peptide sequence by the mathematical model. The present invention is comprising the steps of acquiring a variety of peptide sequence having specific features by the experimental technique; acquiring, on the basis of the sequence, a variety of peptide sequences lacking the specific features; storing the acquired peptide sequences as each set respectively, followed by randomly extracting peptide sequences in the constant ratio to divide into a training set and a test set of mathematical model; allowing individual peptide sequence descriptor values and an activity value; training the set of training peptide by mathematical model; predicting pharmacokinetic parameter of the set of test peptide by the trained mathematical model; and validating the trained mathematical model.