Abstract: Compounds of general formula (Ia), compounds of general formula (Ia?), compounds of general formula (Ib), compounds of general formula (Ib?), compounds of general formula (I), compounds of general formula (I?), and their pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, R6, R8, R9, X1, X2, and X3 are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds of the disclosure.

Abstract: An electric lock includes a cover, a clutch rod, a driving module, a clutch member and a handle. The clutch rod is movably connected to a latch. The driving module is disposed on the cover. The driving module includes a driving member abutting against and rotatable relative to the cover, and a motor configured to drive the driving member to rotate. The handle is connected to the clutch member. Wherein, when the motor drives the driving member to rotate relative to the cover along a first rotating direction, the driving member drives the clutch rod to move toward the handle to be engaged with the clutch member for allowing the handle to drive the latch to move through the clutch rod when the handle is rotated.

Abstract: A semiconductor structure includes a substrate having a plurality of fin structures thereon, an isolation oxide structure in the substrate between adjacent two of the plurality of fin structures, a gate disposed on the plurality of fin structures, a gate dielectric layer disposed between the plurality of fin structures and the gate, and a source/drain doped region in each of the plurality of fin structures. The isolation oxide structure has a concave, curved top surface.

Abstract: Techniques for ranking members based on an influence score are described. For example, an influence score process can access, from a database in an online social network, member data of a first member in response to receiving a ranking request of the first member. Additionally, a contribution factor for each first-degree connection of the first member can be determined. A centrality score for the first member can be determined based on the contribution factor for each first-degree connection of the first member. Moreover, an expertise score for the first member can be determined based on the member data of the first member. Furthermore, an influence score of the first member can be calculated based on the centrality score and the expertise score. Subsequently, a user interface is configured to cause a presentation, on a display of a device, of the ranking of the first member based on the influence score.

Abstract: A control method for operating an electric lock by using a portable device includes the portable device obtaining an encrypted message according to an encryption function; the portable device transmitting the encrypted message to the electric lock; the electric lock decrypting the encrypted message according to a decryption function; and the electric lock determining whether to perform an action according to a decryption result of the encrypted message.

Abstract: A method for adding a user of an electric lock includes receiving a temporary code; establishing a connection between a portable device of the user and the electric lock; inputting and transmitting the temporary code to the electric lock via the portable device; the electric lock determining if the temporary code matches a default password; inputting a user information of the portable device via the portable device when the temporary code matches the default password; and storing the user information in the electric lock, so that the portable device is allowed to drive the electric lock to perform an action.

Abstract: A method includes initiating an emergency call, responsive to the initiating step, generating a trigger, wherein the trigger comprises a request to suspend a call restriction associated with a user device, and transmitting the trigger using a Ut interface to a server to suspend the call restriction.

Abstract: A backlight module for an LCD display includes backlight units. Each backlight unit includes a backplane unit, a first reflecting unit on the backplane unit, an LED on the backplane unit extending through the first reflecting unit, and a light guiding unit on a side of the LED and the first reflecting unit away from the backplane unit. The light guiding unit is transparent. Each backlight unit further includes a second reflecting unit on a side of the light guiding unit away from the backplane unit. The second reflecting unit includes at least one reflecting region and at least one transmitting region. The reflecting region reflects light; the transmitting region allows light to pass through. At least one backlight unit comprises a quantum dot layer.

Abstract: A lightweight and thin backlight module for an LCD display includes backlight units. Each backlight unit includes a backplane unit, a first reflecting unit on the backplane unit, and at least three LEDs on the backplane unit extending through the first reflecting unit, and a light guiding unit on the first reflecting unit away from the backplane unit. The light guiding unit is transparent. Each backlight unit further includes a second reflecting unit on a side of the light guiding unit away from the backplane unit. The second reflecting unit includes at least one reflecting region and at least one transmitting region. The reflecting region reflects light; the transmitting region allows light to pass through.

Abstract: This invention provides a cooperative coverage method for distribution network information perception. The cooperative coverage method includes the following steps: construction of connected cooperative coverage sets, which can cover all target nodes with as few information perception nodes as possible, and maintain the connectivity of each cooperative coverage set with connected sets construction methods based on of hierarchical clustering; Cooperative coverage set scheduling, introducing the concept of energy ratio threshold, dividing the life cycle of the system into multiple time slices, calculating the energy ratio of perception device set in each time slice to realize the set scheduling. The invention realizes the efficient utilization of the energy of the perception device through the construction and scheduling of the connected coverage set in different time slices, and improves the use efficiency of the information perception network.

Abstract: An electronic device comprises a data transmitting interface configured to transmit data, a memory configured to store the data, a processor configured to execute an application program, and an accelerator coupled to the processor via a bus. According to an operation request transmitted from the processor, the accelerator reads the data from the memory, performs an operation to the data to generate computed data, and stores the computed data in the memory. The electronic device can improve computational efficiency. An accelerator and an accelerating method applicable to a neural network operation are also provided.

Abstract: This invention relates to electrophysiological assays that measure sodium conductance activity of a delta human epithelial sodium channel (ENaC) in the presence and absence of delta hENaC enhancers. Also, the invention generally relates to assays for identifying compounds that enhance the activity of delta hENaC, especially in an oocyte expression system. These compounds have potential application in modulating (enhancing) salty taste perception.

Abstract: A presence-based capability discovery mechanism for in-call services in the rich communication services (RCS) release 6 suite of services is provided. A method can comprise receiving a unique identifier representing a communication between a first user device and a second user device, the unique identifier comprising a concatenation of a first string, a second string, and a third string, as a function of the second string, performing a look up of a first presence tuple associated with the first user device; and associating the unique identifier to first presence tuple.

Abstract: An LCD device includes a TFT array substrate, a liquid crystal layer, and a plurality of photo spacers. The photo spacers are located inside the liquid crystal layer. The TFT array substrate includes a pixel electrode layer and an alignment layer. The alignment layer is arranged on the of TFT array substrate on the side near the liquid crystal layer. The pixel electrode layer is arranged on the alignment layer on the side far away from liquid crystal layer; the alignment layer includes a plurality of contact portion. The bottom of the photo spacers are holding with the contact portions. A plurality of block portion is adjacent to the contact portions. The block portion is a protrusion formed toward the color filter substrate with respect to the contact portion, so that the displacement of the photo spacers on the TFT array substrate can be limited.

Abstract: A method for forming epitaxial material on base material includes forming a stress cap layer on a base layer of a first semiconductor material. Then, a stress is induced on the base layer, wherein the stress is a tensile stress or a compressive stress. The stress cap layer is removed. An epitaxial layer of a second semiconductor material is formed on the base layer, wherein the second semiconductor material is different from the first semiconductor material.

Abstract: In one aspect, the present disclosure provides new analogs of uncialamycin. The present disclosure also provides novel synthetic pathways to obtaining uncialamycin and analogs thereof. Additionally, the present disclosure also describes methods of use of uncialamycin and analogs thereof. In another aspect, the present disclosure provides antibody-drug conjugates which may be used to treat cancer or another disease or disorder.

Abstract: An isolated antibody or an antigen-binding fragment thereof having a specific binding affinity to an epitope located within the domain 1 or domain 3 of human vascular endothelial growth factor receptor 2 (VEGFR2; SEQ ID NO: 74) is disclosed. The epitope within the domain 3 of the VEGFR2 is located between amino acid residues 250 and 270 of SEQ ID NO: 74. Use of the antibody or antigen-binding fragment thereof in the manufacture of a medicament for inhibiting tumor growth, tumor angiogenesis, and/or inducing cancer cell cytotoxicity in a subject in need thereof is also disclosed. Also disclosed is a method of detecting the presence of VEGFR2 in a tumor vascular endothelial cell or a cancer cell in a biological sample.

Abstract: This invention relates to novel rationale and methods for identifying human and primate taste-specific genes, including genes involved in salty taste perception, especially human salty taste perception, but also genes involved in sweet, bitter, umami, and sour taste perception, and genes involved in other taste cell or taste receptor related activities such as digestive function and digestive related diseases, taste cell turnover, immunoregulation of the oral and digestive tract, and metabolic regulation such as in diabetes and obesity, the genes identified using these methods, and assays for identifying taste modulators (enhancers or blockers) and potential therapeutics using these genes. These compounds have potential application in modulating (enhancing or blocking) taste perception, especially salty taste perception and as potential therapeutics.

Abstract: Systems and methods are provided for self-describing configurations of cloud-based applications for data security providers monitoring communications between a client device and the applications. An application programming interface (API) can be provided that allows the data security provider to inspect entity objects used by the cloud-based application. Data entities can be marked to have protected fields. A token identifier can be generated by the data security provider and sent to the cloud-based application. The cloud-based application can insert the token identifier in communications between the application and a client device allowing the data security provider to protect sensitive data associated with the protected fields.

Abstract: A conductive layer for a thin film transistor (TFT) array panel includes a multi-layered portion defining a source electrode and a drain electrode of a TFT device, and includes a first sub-layer, a second sub-layer, a third sub-layer, and at least one additional sub-layer. The third and the first sub-layers include indium and zinc oxide materials. An indium to zinc content ratio in the first sub-layer is greater than that in the third sub-layer. An indium to zinc content ratio in the additional sub-layer is formulated between that in the first and the third sub-layers. The content ratio differentiation between the first and the third sub-layers affects a lateral etch profile associated with a gap generated in the second conductive layer between the source and the drain electrodes, where the associated gap width in the third sub-layer is wider than that in the first sub-layer.