Abstract: An LCD display panel with increased screen-to-body ratio includes first and second substrates with a liquid crystal layer disposed between them. The first substrate includes a display portion and at least two edge portions. The second substrate includes a support portion, two extended portions, and a second extended portion. A size of the support portion is same as a size of the display portion. Each first extended portion corresponds to one edge portion. The second extended portion is extended from a side of the support portion and is bent away from the first substrate. Part of the second extended portion is disposed below the display portion, and the electronic elements to drive the display are disposed on surface of the second extended portion.

Abstract: A sensor using ultrasound to detect presence and nature of analyte includes an ultrasonic element and a receptor thereon. The ultrasonic element includes a first electrode, a second electrode facing and spaced apart from the first electrode, an insulating layer between the first electrode and the second electrode, and a vibrating film between the insulating layer and the first electrode. The vibrating film carries the first electrode. A cavity is formed between the vibrating film and the insulating layer. The receptor is on a side of the first electrode away from the second electrode. The receptor can combine with a target substance in a test analyte. When the first electrode and the second electrode are applied with different voltages, certain ultrasound frequencies are generated as the vibrating film vibrates, and the presence and weight of different target substances are indicated by the changes in resonance.

Abstract: An example system and method facilitates operation of a networked software application, i.e., client application which communicates with a network resource (e.g., web service) during periods of intermittent network connectivity, by selectively intercepting and shredding and/or unshredding service response messages. In a specific embodiment, the example system includes one or more pluggable shredders and unshredders that are used to explode a complex REpresentational State Transfer (REST) payload into its constituent structured primitive objects for ease of consumption by the User Interface (UI) of the client application. The exploded, i.e., shredded response message payloads are stored in local cache, where the cached data is strategically structured as compared to the received REST payload. One or more unshredders selectively reconstruct one or more REST response message payloads if client reissues the corresponding REST request message while offline.

Abstract: In various example embodiments, a system and method for generating and routing notifications of content extracted from emails are presented. A member's interest in a specific email among a set of emails are determined based on a relevance score. Content from the specific email are extracted, the content being identified as primary information and secondary information. A notification is generated comprising of the vital content extracted from the specific email. Presentation of the primary information is caused, the primary information being associated with the notification according to a ranked order, the ranked order being based on the relevance score. In response to a member action, presentation of the secondary information is caused, the secondary information being associated with the notification.

Abstract: Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.

Abstract: The present disclosure provides implementation and communication methods, an apparatus and a system of a virtual subscriber identity module. The implementation method includes: receiving a VSIM application request sent by a terminal, where the VSIM application request carries an identifier of a VSIM desired by the terminal; obtaining corresponding VSIM installation information according to the identifier of the desired VSIM; and sending the VSIM installation information to the terminal, so that the terminal installs the VSIM according to the VSIM installation information. The embodiments of the present disclosure effectively solve a problem where an existing mobile operator network does not support the VSIM, and provide an effective and convenient operation scheme for an existing domestic or international roaming service.

Abstract: Compounds of general formula (I), and their pharmaceutically acceptable salts, wherein R1, R2, R3, R5, R6, R8, R9, A, X1, X2, and X3 are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are compositions comprising such compounds, processes for the synthesis of such compounds, and to uses of such compounds, including administration of such compounds to induce immune response, to induce STING-dependent type I interferon production, and/or to treat a cell proliferation disorder, such as cancer.

Abstract: In one aspect, the present disclosure provides new analogs of uncialamycin. The present disclosure also provides novel synthetic pathways to obtaining uncialamycin and analogs thereof. Additionally, the present disclosure also describes methods of use of uncialamycin and analogs thereof. In another aspect, the present disclosure provides antibody-drug conjugates which may be used to treat cancer or another disease or disorder.

Abstract: An example system and method facilitates operation of a networked software application, i.e., client application which communicates with a network resource (e.g., web service) during periods of intermittent network connectivity, by selectively intercepting and shredding and/or unshredding service response messages. In a specific embodiment, the example system includes one or more pluggable shredders and unshredders that are used to explode a complex REpresentational State Transfer (REST) payload into its constituent structured primitive objects for ease of consumption by the User Interface (UI) of the client application. The exploded, i.e., shredded response message payloads are stored in local cache, where the cached data is strategically structured as compared to the received REST payload. One or more unshredders selectively reconstruct one or more REST response message payloads if client reissues the corresponding REST request message while offline.

Abstract: A micro LED display panel defines a display area and a border area surrounding the display area. The micro LED display panel includes a TFT array substrate, a plurality of micro LEDs on the TFT array substrate, a common electrode on the TFT array substrate, the common electrode covering and electrically coupling to all of the micro LEDs; a metal layer on a side of the common electrode away from the TFT array substrate and electrically coupling to the common electrode, and a black photoresist layer on a side of the metal layer away from the TFT array substrate. The black photoresist layer defines through holes. Each through hole extends through both the black photoresist layer and the metal layer and aligns with one micro LED. The metal layer and the black photoresist layer cover the display area and the border area.

Abstract: An electric lock includes a motor, a power input port, a first control system and a second control system. The first control system includes an input unit configured to receive anput data, an internal power source, and a first processing unit configured to use electricity of the internal power source to control the motor to rotate according to the input data. The second control system includes a wireless unit configured to receive a wireless signal, and a second processing unit different from the first processing unit and configured to use electricity of an external power source to control the motor to rotate when data transmitted in the wireless signal matches predetermined data and when the power input port is electrically connected to the external power source.

Abstract: Compounds of general formula (I), of general formula (II), of general formula (III), of general formula (IV), of general formula (V), of general formula (VI), and their pharmaceutically acceptable salts, wherein all variables are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are compositions comprising such compounds, processes for the synthesis of such compounds, and to uses of such compounds, including administration of such compounds to induce immune response, to induce STING-dependent type I interferon production, and/or to treat a cell proliferation disorder, such as cancer.

Abstract: In some embodiments, a management system is configured to dynamically generate and/or adjust a step-by-step care regimen. The care regimen, or step-by-step plan, is broken down by the system into specific actions presented to a patient at specific times with tailored guidance on how to achieve the best effect of each step. The system can be configured to build tailored care plans that span contemplation phases, preparation phases, recovery phases, and long term care phases. In further embodiments, over the treatment life cycle, the system facilitates patient care compliance, planning and education, among other options. In other embodiments, the system is configured to dynamically capture and develop implicit relationship information on a patient's care journey, and augment care options for respective patients responsive to identifying implicit connections developed within the context of the patient's care journey (e.g., specified by patient provider, procedure, physician, comorbidities, etc.).

Abstract: A class of polycyclic compounds of general formula (I), of general formula (I?), or of general formula (I?), wherein Base1, Base2, Y, Ya, Xa, Xa1, Xb, Xb1, Xc, Xc1, Xd, Xd1, R1, R1a, R2, R2a, R3, R4, R4a, R5, R6, R6a, R7, R7a, R8, and R8a are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.