Abstract: The present invention provides a factory power management and control method based on edge-cloud coordination, including: 1) forming an industrial field network by a field node, a routing node and a device executing production tasks; 2) parsing production task information data and sending; 3) issuing an STN model in production field to an edge node; 4) sending to the edge node; 5) computing, required to complete the production tasks; 6) computing values of comprehensive ranks; 7) executing, by the edge node, the higher rank, and executing, by the cloud power management center, the lower rank; 8) executing, by the edge node, a demand response algorithm; 9) executing, by the production device, the production tasks based on computing results; and executing, by a power generation station in factory, a power storage station in factory and a power supply station outside factory, corresponding schemes based on the results.

Abstract: A method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazo-lo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a targeted therapy agent. A pharmaceutical combination comprising a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-( 4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a targeted therapy agent.

Abstract: The invention proposes a method of separating hemicellulose through efficient pretreatment of fibrous biomass materials. Fibrous biomass materials are first pretreated by the slurry method: the fibrous biomass materials are milled through ball mills and sieved to obtain fibrous biomass material powder, and the powder is mixed with water at room temperature to obtain slurry premixed solution of the fibrous biomass material powder. Through regulation and control of the reaction temperature, the time and the water amount, efficient hydrothermal removal of hemicellulose from the fibrous biomass material powder is realized. After the mixed solution is filtered, the filtrate is subject to gradient sedimentation to separate hemicellulose with low dispersity, and the sediment is then dried before storage. After the filter residue is mixed with polar aprotic solvent and water, and heated and stirred in a pressurized reactor, high-purity cellulose is obtained through filtering and separation.

Abstract: A hard drive backplane has a plurality of ventilation holes, and the expansion cavity muffler is mounted in the ventilation holes of the hard drive backplane. The expansion cavity muffler includes at least one expansion cavity and at least one connecting pipe in communication in a first direction. The connecting pipe at one end of the expansion cavity muffler facing toward the hard drive backplane is fixedly mounted in the ventilation hole such that the expansion cavity muffler is in communication with the ventilation hole. An area of a cross-section that is of each expansion cavity and that is perpendicular to the first direction is larger than an area of a cross-section that is of the connecting pipe adjacent to the expansion cavity and that is perpendicular to the first direction. The first direction is perpendicular to a surface of the hard drive backplane.

Abstract: The present disclosure relates to a device and a method for displaying videos. Specifically, the present disclosure provides an electronic device for displaying videos. The electronic device includes: a processor and a memory. The memory is coupled to the processor and includes an executable instruction stored thereon.

Abstract: Provided is a cell-penetrating peptide, which can deliver a variety of biological macromolecules, such as proteins, antibodies, nucleic acids and so on into cells across a membrane. In addition, further provided are a fusion protein, conjugate and complex containing the cell-penetrating peptide, and a use of the cell-penetrating peptide.

Abstract: The present disclosure provides single domain antibodies that bind to CD20, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.

Abstract: A scheduling method applied in an industrial heterogeneous network in which a TSN and a non-TSN are interconnected is provided. The TSSDN controller classifies data flows according to the delay requirements, and calculates the scheduling priorities of the data flows in the industrial heterogeneous network. The TSSDN controller adopts an improved CSPF algorithm to determine a shortest path in the heterogeneous network, and marks the scheduling priorities of the data flows which are transmitted from the subnet of the heterogeneous network and arrive at the switch for the first time. Flow table matching is performed at the SDN switch. In a case of performing flow table matching successfully, the counter is updated and the instruction included in the flow table is executed. In a case of performing flow table matching unsuccessfully, a PacketIn message is transmitted to the TSSDN controller, and the TSSDN controller performs analysis and makes a decision.

Abstract: Disclosed are systems for applying materials to components. The system comprises a tool operable for transferring a portion of a material from a supply of the material to a component. A first portion of the tool may be configured for cutting along a side or edge of the portion of the material. A second portion of the tool may be configured for tamping, pressing, or pushing against the portion of the material to cause uncut sides or edges of the portion of the material attached to the supply of the material to be torn, severed, detached, or separated from the supply of the material.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a targeted therapy agent. Also, disclosed a pharmaceutical combination comprising a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor, or a targeted therapy agent and the use thereof.

Abstract: A housing, a vibration assembly, and a vehicle including the vibration assembly is provided, wherein the housing includes a polymer layer and a metal layer. The metal layer is located at an innermost layer of the housing. A material used for the metal layer includes a metal material. The polymer layer is located on an outer side of the metal layer. A material used for the polymer layer includes a polymer material. The housing can convert mechanical vibration energy into heat energy for dissipation, thereby achieving a noise reduction effect.

Abstract: A unique and novel ready to assembly chair base is broken down into several component parts so that it can be packed in a smaller volume of space, and then easily assembled by the consumer. The chair base is formed in a manner that the base comes apart into at least two components. A first removable leg component and a second hub component consists of a central support with a tapered hole therein, a plurality of fixed legs and a truncated leg receiver configured and arranged receive and retain the removable leg component when the chair is assembled.

Abstract: Provided is a data security sharing method for multiple edge nodes to operate in a collaboration mode under an industrial cloud environment. The method includes: firstly, edge nodes that need collaborative computing separately applying for a shared key to an authority center; secondly, the authority center generating a shared key and issuing the key to each of the edge nodes applying for participation in the collaborative computing; again, the edge nodes combining industrial characteristics to generate an interference factor set, and adding different interference factors for different types of data; then, the data of the edge nodes is implemented with improved homomorphic encryption and is uploaded to an industrial cloud platform; and finally, the industrial cloud platform performing homomorphic analysis and computing on the data uploaded by each of the edge nodes, and issuing the data back to each of the edge nodes.

Abstract: The present invention discloses an monoclonal antibody, which can bind to HyIL-6 with the binding constant 2.86×10?10 and significantly inhibit IL-6/IL-6R/gp130 complex formation. In addition, the monoclonal antibody of the present invention effectively inhibits HyIL-6-stimulated signal transducer and activator of transcription 3(STAT3) activation and related vascular endothelial growth factor (VEGF) induction. Data from hydrogen deuterium exchange mass spectrometry (HDX-MS) demonstrate that the antibody of the present invention mainly binds to site IIIa of IL-6 and blocks the final step in the interaction between gp130 and IL-6/IL-6R complex. Additionally, data from ELISA binding assays and kinetics assays indicate that the antibody of the present invention interacts simultaneously with IL-6 and IL-6R, while it does not interact with IL-6R alone.

Abstract: A method for treating autoimmune and/or inflammatory disease includes a step of identifying a subject exhibiting symptoms of autoimmune and/or inflammatory disease administering a fasting mimicking diet. A probiotic composition for gastrointestinal autoimmune and/or inflammatory disease Bacteroides acidifaciens, Bifidobacterium choerinum, and combinations thereof is also provided.

Abstract: Network device, system, method and computer readable medium for video content processing.

Abstract: An interactive device for animals is provided that includes a main body, a driving module and a first rotating member. The main body includes an accommodating groove, an opening, and a communicating channel. The driving module is disposed on the main body. The first rotating member is rotatably disposed in the main body and separates the communicating channel and the accommodating groove. When the driving module drives the first rotating member to rotate in a first rotating direction, the first rotating member drives at least one object disposed in the accommodating groove to enter the communicating channel and leave the main body through the opening.

Abstract: Disclosed herein is a building assembly for assembling building panels. The building assembly includes a supporting member, a pair of a first sealing member, an elastically deformable gasket, and a second sealing member. The supporting member has a base, a channel disposed at the center of the base, and a pair of rails independently disposed next to the channel. The pair of a first sealing members independently includes a first base portion and two retention tongues independently extending outwardly from the first base portion. The elastically deformable gasket has a U- or V-shaped space in cross section and two flanges independently extending laterally from one edge of the U- or V-shaped space. The second sealing member has a second base portion and a rib disposed at the center of the second base portion.