Patents by Inventor Ming Hsieh

Ming Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9062101
    Abstract: The present invention relates to amyloid-beta (A?) binding proteins. Antibodies of the invention have high affinity to A?(20-42) globulomer or any A? form that comprises the globulomer epitope. Method of making and method of using the antibodies of the invention are also provided.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: June 23, 2015
    Assignees: AbbVie Deutschland GmbH & Co. KG, AbbVie Inc.
    Inventors: Stefan Barghorn, Heinz Hillen, Andreas Striebinger, Simone Giaisi, Ulrich Ebert, Chung-Ming Hsieh
  • Publication number: 20150142229
    Abstract: Apparatuses, methods and systems for hybrid powertrain control are disclosed. Certain example embodiments control an internal combustion engine and a motor/generator of a hybrid electric powertrain. Example controls may determine a total output demanded of a powertrain based at least in part upon an operator input, a battery output target based upon a battery state of charge and independent of the operator input, and an engine output target based upon the total output demanded and the battery output target. Such example controls may further determine a constrained engine output target, a modified battery output target based upon the total output demanded and the constrained engine output target, and a constrained battery output target based upon the modified battery output target and a battery constraint. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the following description and figures.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 21, 2015
    Applicant: CUMMINS INC.
    Inventors: Martin T. Books, Vincent Freyermuth, Tung-Ming Hsieh, Praveen Muralidhar, Lining Zhou
  • Publication number: 20150111251
    Abstract: TNF-? binding proteins, including chimeric, CDR-grafted, and humanized antibodies that bind TNF-? are provided. Binding proteins have high affinity for TNF-? and neutralize TNF-? activity. A binding protein can be a full-length antibody or a TNF-?-binding portion thereof. Methods of making and methods of using the binding proteins are also described. The TNF-? binding proteins are useful for detecting TNF-? and for inhibiting TNF-? activity, including in a human subject suffering from a disease or disorder in which TNF-? activity is detrimental.
    Type: Application
    Filed: September 25, 2014
    Publication date: April 23, 2015
    Inventors: Chung-ming HSIEH, Carrie GOODREAU, Tariq GHAYUR, Achim MOELLER, Sahana BOSE
  • Patent number: 8999331
    Abstract: Proteins that bind sclerostin or sclerostin and TNF are described along with there use in composition and methods for treating, preventing, and diagnosing sclerostin related diseases and for detecting sclerostin or sclerostin and TNF in cells, tissues, samples, and compositions.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: April 7, 2015
    Assignee: AbbVie Inc.
    Inventors: Chung-Ming Hsieh, Alexander Ivanov, Wendy Waegell, Yuliya Kutskova, John Memmott, Lorenzo Benatuil, Jacqueline Bixby, Emma Fung, Sahana Bose, Alyssa Brito
  • Publication number: 20150093387
    Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
    Type: Application
    Filed: August 22, 2014
    Publication date: April 2, 2015
    Inventors: Chengbin Wu, Dominic J. Ambrosi, Chung-ming Hsieh, Tariq Ghayur
  • Publication number: 20150078412
    Abstract: A chip array structure for laser diodes, formed on an active surface of a semiconductor chip produced from a semiconductor process includes a plurality of light-emitting elements in an array arrangement, at least one insulation wall, at least two wire bond areas and a plurality of connection electrodes. The insulation wall separates the light-emitting elements into at least two light-emitting districts. The wire bond areas are positioned respective to the corresponding light-emitting districts. The connection electrodes electrically couple the wire bond areas with the corresponding light-emitting districts. The wire bond areas have independent electrodes, and the light-emitting districts are electrically isolated by the insulation wall.
    Type: Application
    Filed: September 19, 2014
    Publication date: March 19, 2015
    Applicant: TrueLight Corporation
    Inventors: Jin-Shan Pan, Chih-Cheng Chen, Hsiu-Ming Hsieh
  • Publication number: 20150075960
    Abstract: A touch panel including a substrate, at least one decoration layer, and a conductive electrode structure is provided. The decoration layer is disposed on at least one side of the substrate. The decoration layer has at least one hot key area. The hot key area includes a hot key pattern area and a hot key touching area. The hot key touching area is located on at least one side of the hot key pattern area without overlapping each other. The decoration layer has at least one recess disposed in the hot key pattern area. The conductive electrode structure is disposed on the decoration layer. The conductive electrode structure is located in the hot key touching area, and an orthogonal projection of the conductive electrode structure on the substrate and an orthogonal projection of the recess on the substrate do not overlap with each other.
    Type: Application
    Filed: September 12, 2014
    Publication date: March 19, 2015
    Applicant: WINTEK CORPORATION
    Inventors: Chi-Ming Hsieh, Shyh-Jeng Chen, Chia-Lun Chang, Chun-Ming Huang, Kuo-Hsing Chen, Chen-Hao Su
  • Publication number: 20150067405
    Abstract: Embodiments of the invention relate to a system comprising a processor, a burst detection module executing on the processor, and a resource monitor. The burst detection module is configured to receive a set of resource usages samples measuring an availability of a resource, calculate an absolute moving average (AMA) of the set of resource usage samples, calculate a mean dispersion of the set of resource usage samples, and determine that the set of resource usage samples comprises an aberrant sample by comparing the AMA to the mean dispersion. The resource monitor is configured to execute a recovery procedure in response to the determination that the set of resource usage samples comprise the aberrant sample.
    Type: Application
    Filed: August 27, 2013
    Publication date: March 5, 2015
    Applicant: Oracle International Corporation
    Inventors: Teh-Ming Hsieh, Liang Dong
  • Patent number: 8962803
    Abstract: The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind and neutralize RGM A protein. Specifically, these antibodies have the ability to inhibit the binding of RGM A to its receptor and/or coreceptors. These antibodies or portions thereof of the invention are useful for detecting RGM A and for inhibiting RGM A activity, for example in a human suffering from a disorder including but nor limited to multiple sclerosis, mammalian brain trauma, spinal cord injury, stroke, neurodegenerative diseases, and schizophrenia.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: February 24, 2015
    Assignees: AbbVie Deutschland GmbH & Co. KG, AbbVie Inc.
    Inventors: Bernhard K. Mueller, Martin Schmidt, Eve Barlow, Mary Leddy, Chung-Ming Hsieh, Philip Bardwell
  • Patent number: 8935110
    Abstract: A system for analyzing an interior energy system including: at least one detachable sensor arranged to monitor a portion of the interior energy system; and an apparatus including a processor configured to receive data of a first parameter of the interior energy system from the at least one detachable sensor and determine a second parameter of the interior energy which is inferred on the basis of the received data of the first parameter; and determine a characteristic of the interior energy system from the determined second parameter. The system may provide analysis of the interior energy system and recommend improvements.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: January 13, 2015
    Assignee: The Technology Partnership PLC
    Inventors: Mark Chang-Ming Hsieh, David Russell Anderson
  • Publication number: 20140373270
    Abstract: An improved opening for a metal faucet has an outlet neck having an opening with an outer threaded section at an outer edge and a curved stopping ring at the opening, the stopping ring having a rounded surface at an inner edge. The improved opening for a metal faucet which does not have any sharp edge and provide smooth water flows.
    Type: Application
    Filed: June 19, 2013
    Publication date: December 25, 2014
    Inventor: CHIN-MING HSIEH
  • Patent number: 8916504
    Abstract: The present invention features improved methods of in vitro RNA display to allow reliable expression and selection of scFv antibody molecules from expression libraries. The improved methods, in part, involve the use of mildly reducing conditions, which favor of scFv intra-chain disulphide bond and thus correct folding of the scFv antibody molecules. Although particularly suited to expression and selection of scFv antibody molecules, the methods of the invention are also expedient for in vitro RNA display of all classes of protein.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: December 23, 2014
    Assignee: Abbvie Inc.
    Inventors: Chung-Ming Hsieh, Yuliya A. Kutskova, John E. Memmott
  • Publication number: 20140368755
    Abstract: A touch panel includes a substrate having a light-shielding region and a light-transmission region, a first conductive pattern disposed on the substrate, and a second conductive pattern disposed on the substrate in the light-shielding region. The first conductive pattern includes a plurality of peripheral electrodes extending from the light-transmission region into the light-shielding region. Each peripheral electrode includes a connecting part disposed in the light-shielding region. Each connecting part has two first sides opposite to each other. The second conductive pattern includes a plurality of connecting electrodes, and each connecting electrode is electrically connected to and partially overlaps each connecting part. Each connecting electrode has two second sides, and the second sides are disposed between the first sides.
    Type: Application
    Filed: June 12, 2014
    Publication date: December 18, 2014
    Inventors: Chun-Ho Chen, Tsung-Yu Wang, Kuo-Chang Su, Chih-Jung Teng, Chi-Ming Hsieh
  • Publication number: 20140356909
    Abstract: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
    Type: Application
    Filed: April 28, 2014
    Publication date: December 4, 2014
    Applicant: ABBVIE INC.
    Inventors: Chung-Ming Hsieh, Margaret Hugunin, Anwar Murtaza, Bradford L. McRae, Yuliya Kutskova, John E. Memmott, Jennifer M. Perez, Suju Zhong, Edit Tarcsa, Anca Clabbers, Craig Wallace, Shaughn H. Bryant, Mary R. Leddy
  • Publication number: 20140354056
    Abstract: An uninterruptible power supply system including a rectification circuit, a power calibrating conversion circuit, an inverting conversion circuit, an LC circuit, a first output switch, a second output switch and a relay switch is disclosed. The rectification circuit couples to the main electricity. The power calibrating conversion circuit couples to the rectification circuit, and includes an independent drive unit and a switch unit. The inverting conversion circuit couples to the power calibrating conversion circuit. The LC circuit couples between output neutral terminal and output ground terminal. The first output switch couples between the LC circuit and the inverting conversion circuit. The second output switch couples between the inverting conversion circuit and output live terminal. The relay switch couples between the input neutral terminal and the LC circuit. When the relay switch turns on, the input neutral terminal connects with the output neutral terminal through the LC circuit.
    Type: Application
    Filed: May 29, 2013
    Publication date: December 4, 2014
    Inventors: MING-HSIEN CHEN, JUOR-MING HSIEH
  • Publication number: 20140346670
    Abstract: A multilayer substrate includes a first outer conductive patterned layer, a first insulating layer exposing a portion of the first outer conductive patterned layer to define a first set of pads, a second outer conductive patterned layer, and a second insulating layer exposing a portion of the second outer conductive patterned layer to define a second set of pads. The multilayer substrate further includes inner layers each with an inner conductive patterned layer, multiple inner conductive posts formed adjacent to the inner conductive patterned layer, and an inner dielectric layer, where the inner conductive patterned layer and the inner conductive posts are embedded in the inner dielectric layer, and a top surface of each of the inner conductive posts is exposed from the inner dielectric layer.
    Type: Application
    Filed: August 6, 2014
    Publication date: November 27, 2014
    Inventors: Yuan-Chang Su, Shih-Fu Huang, Chia-Cheng Chen, Tzu-Hui Chen, Kuang-Hsiung Chen, Pao-Ming Hsieh, Ming Chiang Lee, Bernd Karl Appelt
  • Publication number: 20140348856
    Abstract: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
    Type: Application
    Filed: April 25, 2014
    Publication date: November 27, 2014
    Applicant: ABBVIE INC.
    Inventors: Chung-Ming Hsieh, Margaret Hugunin, Anwar Murtaza, Bradford L. McRae, Yuliya Kutskova, John E. Memmott, Jennifer M. Perez, Suju Zhong, Edit Tarcsa, Anca Clabbers, Craig Wallace, Shaughn H. Bryant, Mary R. Leddy
  • Publication number: 20140348834
    Abstract: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
    Type: Application
    Filed: April 23, 2014
    Publication date: November 27, 2014
    Applicant: ABBVIE INC.
    Inventors: Chung-Ming Hsieh, Margaret Hugunin, Anwar Murtaza, Bradford L. McRae, Yuliya Kutskova, John E. Memmott, Jennifer M. Perez, Suju Zhong, Edit Tarcsa, Anca Clabbers, Craig Wallace, Shaughn H. Bryant, Mary R. Leddy
  • Publication number: 20140343267
    Abstract: Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
    Type: Application
    Filed: April 24, 2014
    Publication date: November 20, 2014
    Applicant: ABBVIE INC.
    Inventors: Chung-Ming Hsieh, Margaret Hugunin, Anwar Murtaza, Bradford L. McRae, Yuliya Kutskova, John E. Memmott, Jennifer M. Perez, Suju Zhong, Edit Tarcsa, Anca Clabbers, Craig Wallace, Shaughn H. Bryant, Mary R. Leddy
  • Publication number: 20140335564
    Abstract: Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
    Type: Application
    Filed: April 22, 2014
    Publication date: November 13, 2014
    Applicant: ABBVIE INC.
    Inventors: Chung-Ming Hsieh, Margaret Hugunin, Anwar Murtaza, Bradford L. McRae, Yuliya Kutskova, John E. Memmott, Jennifer M. Perez, Suju Zhong, Edit Tarcsa, Anca Clabbers, Craig Wallace, Shaughn H. Bryant, Mary R. Leddy