Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Abstract: An accommodating intraocular lens (AIOL) includes an optic adapted to produce a trapezoidal phase shift and a plurality of haptics. Each haptic extends from a haptic-optic junction to at least one transverse arm contacting a capsular bag of the eye, and each haptic has sufficient length and rigidity to stretch a capsular bag of the eye to contact ciliary muscles of the eye. The haptic-optic junctions vault the optic forward relative to the haptics and compression of the haptics by the ciliary muscles moves the anterior optic forward. A combined accommodative power produced by the motion of the anterior optic and the trapezoidal phase shift is at least 0.5 Diopters.

Abstract: The present invention is generally directed to accommodative intraocular lenses (IOLs) that exhibit a dynamic spherical aberration as a function of accommodative power. By way of example, in one aspect, the present invention provides an intraocular lens (IOL) having an anterior optical element, a posterior optical element, and a mechanism for coupling the anterior and posterior elements so as to allow axial movement of those elements relative to one another for providing accommodation when the lens is implanted in a patient's eye. Each of the anterior and the posterior elements includes at least one aspherical surface, where the asphericities of the surfaces are adapted to provide a combined spherical aberration that varies with accommodation.

Abstract: A diffractive multifocal design for ocular implant is provided. This ocular implant includes a diffractive multifocal intraocular lens (IOL) and a number of haptics. The diffractive multifocal IOL passes optical energy to distance, intermediate and near foci. The haptics mechanically couple to the diffractive multifocal IOL in order to position and secure the diffractive multifocal IOL within the eye. The diffractive multifocal IOL may include both a diffractive region and a refractive region, the diffractive multifocal IOL operable to phase shift optical energy such that constructive interference occurs within the diffractive region and the refractive region.

Abstract: In one aspect, the present invention provides a method of designing an intraocular lens (IOL) to address variations of at least one ocular parameter in a population of patient eyes. The method can include establishing at least one eye model in which the ocular parameter can be varied over a range exhibited by the population. The eye model can be employed to evaluate a plurality of IOL designs in correcting visual acuity for eyes in the patient population. An IOL design that provides a best fit for visual performance over at least a portion of the parameter range can then be selected.

Abstract: In one aspect, the present invention provides a method of designing an intraocular lens (IOL) to address variations of at least one ocular parameter in a population of patient eyes. The method can include establishing at least one eye model in which the ocular parameter can be varied over a range exhibited by the population. The eye model can be employed to evaluate a plurality of IOL designs in correcting visual acuity for eyes in the patient population. An IOL design that provides a best fit for visual performance over at least a portion of the parameter range can then be selected.

Abstract: In one aspect, the present invention provides a method of designing a diffractive ophthalmic lens (e.g., an intraocular lens (IOL)) that includes providing an optic having an anterior refractive surface and a posterior refractive surface, wherein the optic provides a far-focus power (e.g., in a range of about 18 to about 26 Diopters (D)). A truncated diffractive structure can be disposed on at least one of the surfaces for generating a near-focus add power (e.g., in a range of about 3 D to about 4 D). And the diffractive structure can be adjusted so as to obtain a desired distribution of optical energy between the near and far foci for a range of pupil sizes.

Abstract: An ophthalmic lens includes an optical filter operable to filter out at least visible light having a wavelength less than 450 nm. The lens also includes a first diffractive structure adapted to produce a focus for visible light in a first wavelength range above 550 nm and to reduce longitudinal chromatic aberration to less than one diopter for incoming visible light in the first wavelength range. The lens also includes a second diffractive structure outside the first diffractive structure in a radial direction and adapted to produce a focus for visible light in a second wavelength range between 450 nm and 550 nm. The second diffractive structure is also adapted to reduce longitudinal chromatic aberration for incoming visible light in the second wavelength range to less than one diopter while allowing longitudinal chromatic aberration in the first wavelength range in an amount greater than the first diffractive structure.

Abstract: In one aspect, the present invention provides a method of designing an intraocular lens (IOL) to address variations of at least one ocular parameter in a population of patient eyes. The method can include establishing at least one eye model in which the ocular parameter can be varied over a range exhibited by the population. The eye model can be employed to evaluate a plurality of IOL designs in correcting visual acuity for eyes in the patient population. An IOL design that provides a best fit for visual performance over at least a portion of the parameter range can then be selected.

Abstract: In one aspect, the present invention provides a method for correcting vision that employs two lenses, at least one of which is a multifocal lens, with different focusing characteristics for use in the two eyes of the patient. The visual performance of each lens (e.g., visual contrast or acuity) is selected in accordance with a predefined relation so as to optimize the binocular visual performance provided by the combination of the lenses.

Abstract: An intraocular lens (IOL) delivery device is disclosed. The device includes an intraocular lens cartridge having an internal coating wherein the coating includes a polymeric material that is compatible with a polymeric material of a material that forms the cartridge. Preferably, the polymeric material of the coating, the cartridge or both is a polyurethane material.

Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Abstract: Disclosed are ophthalmic device materials having improved light transmission characteristics. The materials contain a combination of certain UV absorbers and blue-light absorbing chromophores.

Abstract: Disclosed are soft, high refractive index device materials having improved strength. The materials contain a monofunctional or difunctional, acrylate or methacrylate terminated aromatic functional methacrylic or acrylic macromer.

Abstract: In one aspect, the present invention provides an intraocular lens (IOL), which comprises at least two optics disposed in tandem along an optical axis, and an accommodative mechanism that is coupled to at least one of the optics and is adapted to adjust a combined optical power of the optics in response to natural accommodative forces of an eye in which the optics are implanted so as to provide accommodation. At least one of the optics has a surface characterized by a first refractive region, a second refractive region and transition region therebetween, where an optical phase shift of incident light having a design wavelength (e.g., 550 nm) across the transition region corresponds to a non-integer fraction of that wavelength.

Abstract: In one aspect, the present invention provides a method of correcting vision, which comprises determining a residual accommodation exhibited by a natural, crystalline lens of an eye, and selecting a multifocal intraocular lens (IOL), which exhibits a far-focus optical power (e.g., in a range of about ?15 to about +50 Diopters (D)) and an add power (e.g., in a range of about 1 D to about 4 D), for implantation in the eye while retaining the natural lens. The add power of the IOL is selected as a function of the residual accommodation such that a combination of the IOL and the natural lens provides a visual contrast greater than about 10% at a spatial frequency of about 20 cycles/degree for viewing objects at a distance greater than about 30 cm from the eye.

Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract: An improved multifocal design for an ocular implant is provided. This ocular implant includes an intraocular lens (IOL) and a number of haptics. The IOL passes optical energy. A microstructure within the IOL places the IOL under tension. The microstructure is operable to be broken in a controlled manner to release tension in the IOL and reshape the IOL. This may be done at any time post operatively and in conjunction with wavefront aberrometry to provide improved results. The haptics mechanically couple to the IOL in order to position and secure the IOL within the eye.

Abstract: In one aspect, the present invention provides a method of designing an ocular implant (e.g., an IOL), which comprises establishing corneal topography of a patient's eye, e.g., by performing one or more wavefront aberration measurements of the eye, prior to an ocular surgery. The method further includes ascertaining an astigmatic aberration of the cornea that is expected to be induced by the surgery and determining a toricity of a surface of an ocular implant, which is intended for implantation in the patient's eye, so as to enable the implant to compensate for the surgically-induced aberration.

Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain an aryl acrylic hydrophobic monomer as the single principal device-forming monomer and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.