Patents by Inventor Mutlu Karakelle

Mutlu Karakelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6806337
    Abstract: Disclosed are soft, high refractive index, acrylic device materials having improved strength. The materials contain cross-linked acrylate or methacrylate microspheres.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: October 19, 2004
    Assignee: Alcon
    Inventors: Douglas C. Schlueter, Albert R. LeBoeuf, Mutlu Karakelle
  • Patent number: 6703466
    Abstract: Foldable intraocular lenses having a reduced risk of posterior capsule opacification are disclosed. The foldable intraocular lenses have optics that are prepared such that their surface is glassy and their bulk is rubbery.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: March 9, 2004
    Assignee: Alcon, Inc.
    Inventors: Mutlu Karakelle, Joseph D. Menczel, Robert A. Scott, Charles Freeman
  • Publication number: 20040019131
    Abstract: Disclosed are soft, high refractive index, acrylic device materials having improved strength. The materials contain cross-linked acrylate or methacrylate microspheres.
    Type: Application
    Filed: July 15, 2003
    Publication date: January 29, 2004
    Applicant: Alcon, Inc.
    Inventors: Douglas C. Schlueter, Albert R. LeBoeuf, Mutlu Karakelle
  • Publication number: 20040019010
    Abstract: Disclosed are carrageenan-based transitional viscoelastics that will induce little or no IOP spike when left in the eye at the close of surgery thereon. Drug delivery systems for delivering therapeutic agents during post-operative recovery stages are also disclosed.
    Type: Application
    Filed: April 24, 2002
    Publication date: January 29, 2004
    Inventors: Mutlu Karakelle, Michael R Brunstedt
  • Publication number: 20030189688
    Abstract: A method for measuring anterior chamber dimensions using optical coherence tomography. Such a method is more accurate and reliable in determine anterior chamber angle diameter and other anterior chamber dimensions.
    Type: Application
    Filed: April 3, 2002
    Publication date: October 9, 2003
    Inventor: Mutlu Karakelle
  • Publication number: 20030060447
    Abstract: Non-aspirating viscoelastics, compositions and methods of use are disclosed. The non-aspirating, transitional viscoelastics possess sufficient viscosity to be useful in ophthalmic viscosurgery, but may be left in the eye with little or no resulting IOP spike.
    Type: Application
    Filed: April 24, 2002
    Publication date: March 27, 2003
    Inventors: Mutlu Karakelle, David L. Jinkerson, Michael R. Brunstedt, Anilbhai S. Patel, Kwan Y. Chan
  • Patent number: 6491721
    Abstract: A method of selecting an intraocular lens material for toric lenses is disclosed. The method comprises determining the tack of the material.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: December 10, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Charles Freeman, Mutlu Karakelle, Michael J. Simpson
  • Patent number: 6482230
    Abstract: A method for determining the propensity of an intraocular lens material to prevent posterior capsule opacification is disclosed. The method involves contacting a sample of an IOL material having the shape of an IOL optic with collagen to form a contact area, incubating the sample in a liquid composition comprising lens epithelial cells, determining whether lens epithelial cells grow on the collagen in the contact area.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: November 19, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Kwan Chan, John W. Sheets, Jr., Mutlu Karakelle
  • Patent number: 6462082
    Abstract: The use of HETE derivatives in intraocular surgery (e.g., cataract surgery) is disclosed. The HETE derivatives protect and maintain the corneal endothelium.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: October 8, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Mutlu Karakelle, Kwan Chan
  • Publication number: 20020103257
    Abstract: The use of HETE derivatives in intraocular surgery (e.g., cataract surgery) is disclosed. The HETE derivatives protect and maintain the corneal endothelium.
    Type: Application
    Filed: September 27, 2001
    Publication date: August 1, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Mutlu Karakelle, Kwan Chan
  • Publication number: 20020028330
    Abstract: The application of switchable tackiness coating compositions to ophthalmic implants provides the benefits of body temperature tackiness without the disadvantages of room temperature tackiness.
    Type: Application
    Filed: August 24, 2001
    Publication date: March 7, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Anilbhai S. Patel, Douglas C. Schlueter, Mutlu Karakelle
  • Patent number: 6353069
    Abstract: High refractive index copolymers suitable for use in ophthalmic devices are disclosed. The copolymers comprise a) two or more monomers of the structure: wherein: X is H or CH3; m is 0-10; Y is nothing, O, S, or NR wherein R is H, CH3, CnH2n+1(n=1-10), iso-OC3H7, C6H5, or CH2C6H5; Ar is any aromatic ring which can be unsubstituted or substituted with H, CH3, C2H5, n-C3H7, iso-C3H7, OCH3, C6H11, Cl, Br, C6H5, or CH2C6H5; a crosslinking monomer having a plurality of polymerizable ethylenically unsaturated groups, and b) a total of about 5 mole % or less of one or more monomers of the structure: wherein: X is H or CH3; W is —CH3 or (CH2═C(—X)—C(═O)—); and n is such that the weight average molecular weight is approximately 600-1000 if W is —CH3 and approximately 400-1000 if W is (CH2═C(—X)—C(═O)—).
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Charles Freeman, David L. Jinkerson, Mutlu Karakelle, Albert R. Leboeuf
  • Publication number: 20010037150
    Abstract: IOL bodies comprising materials having a Fibronectin/Vitronectin Compatibility Index>1 and a Lens Epithelial Cell Growth Biocompatibility Index≧1 on their posterior surface have a low incidence of posterior capsule opacification.
    Type: Application
    Filed: April 5, 2001
    Publication date: November 1, 2001
    Inventors: Kwan Y. Chan, Mutlu Karakelle, Reijo Linnola
  • Publication number: 20010018612
    Abstract: A diffractive optical ICL made from two different hydrogel materials that are biologically acceptable for long term implantation in the cornea. The first material has a higher refractive index than the cornea and it is bound to the second material which has a refractive index similar to corneal tissue. The interface between the two materials consists of a microstructured diffractive surface. The adequate permeability of metabolites through both of the hydrogels of the diffractive ICL yields a safe implant for the cornea. Alternatively, the lens may be made of a single material and/or have an edge geometry that minimizes corneal irritation and allows the lens to sit within the corneal tissue smoothly and relatively flat.
    Type: Application
    Filed: March 2, 2001
    Publication date: August 30, 2001
    Inventors: Daniel R. Carson, Kwan Y. Chan, John M. Evans, Mutlu Karakelle, Albert R. LeBoeuf, Gregory S. Milios, Anilbhai S. Patel, Michael J. Simpson, Yin Yang
  • Publication number: 20010014824
    Abstract: A method of selecting an intraocular lens material for toric lenses is disclosed. The method comprises determining the tack of the material.
    Type: Application
    Filed: January 16, 2001
    Publication date: August 16, 2001
    Inventors: Charles Freeman, Mutlu Karakelle, Michael J. Simpson
  • Publication number: 20010003162
    Abstract: A method of selecting an intraocular lens material for toric lenses is disclosed. The method comprises determining the material's Collagen IV Index.
    Type: Application
    Filed: January 16, 2001
    Publication date: June 7, 2001
    Inventors: Kwan Chan, Mutlu Karakelle, Michael J. Simpson
  • Patent number: 6210438
    Abstract: Bicomposite intraocular lenses having an anterior surface material different from a posterior surface material are disclosed. The posterior surface material reduces the risk of posterior capsule opacification.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: April 3, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: John W. Sheets, Jr., Albert R. Leboeuf, Anilbhai S. Patel, Mutlu Karakelle, Stephen J. Van Noy
  • Patent number: 6187042
    Abstract: Intraocular lens coating compositions for reducing the risk of posterior capsule opacification are disclosed. The coating materials, which differ from the substrate material, consist essentially of at least two aryl acrylic hydrophobic monomers of the formula wherein: X is H or CH3; m is 0-10; Y is nothing, O, S, or NR wherein R is H, CH3, CnH2n+1 (n=1−10) iso OC3H7, C6H5, or CH2C6H5; Ar is any aromatic ring which can be unsubstituted or substituted with CH3, C2H5, n-C3H7, iso-C3H7, OCH3, C6H11, Cl, Br, C6H5, or CH2C6H5.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: February 13, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: John W. Sheets, Jr., Albert R. Leboeuf, Anilbhai S. Patel, Mutlu Karakelle, Stephen J. Van Noy
  • Patent number: 6015842
    Abstract: Foldable, hydrophilic, ophthalmic device materials are cured by exposure to blue light using a benzoylphosphine oxide photoinitiator.
    Type: Grant
    Filed: August 7, 1997
    Date of Patent: January 18, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Albert R. LeBoeuf, Mutlu Karakelle
  • Patent number: 6001128
    Abstract: Improved glaucoma filtration device materials comprise at least one monomer having the formula: ##STR1## wherein: X is H or CH.sub.3 ;m is 0-10;Y is nothing, O, or S;R is nothing, H, or an aliphatic, aromatic or aliphatic/aromatic combination of up to twelve carbon atoms, which can be unsubstituted or substituted with Cl, F, Br, or an alkoxy of up to four carbon atoms; anda cross-linking monomer having two or more ethylenically unsaturated groups.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: December 14, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Gustav Graff, Mutlu Karakelle, John W. Sheets, Jr., John M. Yanni