Abstract: Disclosed are a cleaning robot system and its method for controlling which make it possible to reliably and quickly clean with the aid of the cleaning robot. The cleaning robot system comprises at least one external device each formed of an indicator and a virtual wall setting function, with the aid of which cleaning work can be performed by the unit of blocks about a cleaning area reference point, not leaving non-cleaned area behind. Since the access of the cleaning robot can be restricted by means of a virtual wall set by an external device, any damages of furniture due to a collision of the cleaning robot can be prevented, and the cleaning robot can be barred from escaping from the set cleaning area.

Abstract: Disclosed are a novel thiazole-containing benzophenone derivative represented by formula 1, and an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof and a solvate thereof, a pharmaceutical composition comprising the derivative, a use of the derivative as therapeutic agent and a method for preparing the derivative. The benzophenone thiazole derivatives inhibit formation of microtubules and eliminate actively proliferating cells of malignant tumors to control general cell proliferation. In formula 1, R, R1 and R2 are defined as above.

Abstract: The present invention relates to imatinib dichloroacetate and an anti-cancer agent comprising the same. The imatinib dichloroacetate of the present invention can inhibit tyrosine kinase as well as induce cancer cells to kill themselves via apoptosis, thereby inhibit growth of cancer cells and lead to their destruction, and show significantly enhanced anti-cancer effects by synergy between imatinib and dichloroacetic acid.

Abstract: Provided is a method of designing a coaxial dual-tube type hot gas duct for a very-high-temperature reactor. When determining the outer diameter of an inner tube and the inner diameter of a pressure tube, both of which defines an annular part of the hot gas duct having a dual-tube shape, one selected from hydraulic heads, flow rates, and hydraulic heads of very-high-temperature helium gas flowing to a very-high-temperature region and low-temperature helium gas flowing to a low-temperature region is taken into consideration as well as is a relation of about heat balance model, so that it is possible to minimize flow induced vibrations caused by the flow of a fluid.

Abstract: The present invention relates to piperazine dithioctate, a novel addition salt of thioctic acid with a base and a pharmaceutical composition comprising the same. The piperazine dithioctate according to the present invention has good thermal and moisture stability and high water-solubility as well as dosage increase lower than other addition salts, thereby being effectively used for preparing a pharmaceutical composition for antioxidation or for preventing or treating diabetic polyneuropathy, etc.

Abstract: A grid strap includes a spacer grid spring that increases the conformal contact area with a fuel rod of a nuclear fuel rod assembly. The shape of the spacer grid spring is optimized, thereby increasing the elasticity of the spacer grid spring contacting the fuel rod, expanding the conformal contact area with a contact portion between the spacer grid spring and fuel rod to obtain uniform stress distribution, and reducing excessive plastic deformation of the spacer grid spring. Further, magnitude and distribution of contact pressure between the fuel rod and the spacer grid spring are improved, thereby reducing the possibility of fretting wear caused by contact between the fuel rod and the spacer grid spring. Lastly, the elastic behavior region of the spacer grid spring is expanded, so that the fuel rod can be reliably supported until the fuel rod expires despite changes in the supporting conditions of the fuel rod.

Abstract: Provided is a multi-valued dynamic random access memory (DRAM) cell using a single electron transistor (SET). The multi-valued DRAM cell using the SET applies different refresh signals to a load current transistor for controlling current supply to the SET and a voltage control transistor for controlling a terminal voltage of the SET and refreshes a data value stored in the SET by a predetermined period to reduce standby current and stably supply a voltage low enough to satisfy a coulomb-blockade condition to the terminal of the SET.

Abstract: Disclosed herein are novel benzophenone derivatives represented by formula I, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, a pharmacological composition containing the same, and a use of the composition as therapeutic drugs. The benzophenone derivatives have an inhibition activity of microtubule formation and can be used to treat a normal proliferative state of a malignant tumor by killing the actively proliferating cells.

Abstract: Provided herein is an MV DRAM device for storing multiple value levels using an SET device. The device includes one or more word lines; one or more bitlines; a DRAM cell connected to intersections of the word lines and the bitlines; a current source transistor having a source connected to a power supply voltage and a gate and a drain connected to the bitlines; an SET (single electron transistor) device having a gate connected to the bitlines and a source connected to the ground voltage; and a transistor connected between the bitlines and the drain of the SET device, where the gate of the transistor is connected to the ground voltage.

Abstract: An apparatus and method for welding strap connections between inner grid straps of a spacer grid using a laser tool, and a spacer grid manufactured by the same, in which the strap connections between the inner grid straps of the spacer grid are seam-welded continuously or intermittently using the laser tool, so that the structural strength of the spacer grid is increased, a spattering phenomenon, in which a welded material is spattered during welding, is reduced, and thermal deformation is reduced. Further, fine welding is possible, and thus the welded bead of each strap connection between the inner grid straps can have a small size, and the number of welding defects can be reduced. In addition, the flow resistance of a coolant is reduced, and thereby the pressure drop of the coolant can be reduced As a result, the load on a flow pump for the coolant can be reduced, and economic efficiency and safety can be improved.

Abstract: Provided is a method of designing a coaxial dual-tube type hot gas duct for a very-high-temperature reactor. When determining the outer diameter of an inner tube and the inner diameter of a pressure tube, both of which defines an annular part of the hot gas duct having a dual-tube shape, one selected from hydraulic heads, flow rates, and hydraulic heads of very-high-temperature helium gas flowing to a very-high-temperature region and low-temperature helium gas flowing to a low-temperature region is taken into consideration as well as is a relation of about heat balance model, so that it is possible to minimize flow induced vibrations caused by the flow of a fluid.

Abstract: Provided herein include compositions, all related stereoisomers as well as pharmaceutically acceptable salts provided as simplified analogs of pateamine A, in which the analogs generally are devoid of the C3-amino and C5-methyl groups, also referred to as desmethyl, desamino-pateamine A. Suitable analogs provide anticancer and antiproliferative effects in vivo and in vitro by a novel drugs mechanism of action described herein for pateamine A, including inhibition of eIF4A-dependent translation initiation. As with pateamine A, as described herein, suitable analogs cause cell cycle arrest or induce apoptosis in transformed cells. However, toxicity of such compounds to slow growing normal cells is low. In addition, such analogs, like pateamine A, target translation initiation factors and are useful as anticancer and antiproliferative agents in subjects in need thereof.

Abstract: Disclosed are a novel thiazole-containing benzophenone derivative represented by formula 1, and an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof and a solvate thereof, a pharmaceutical composition comprising the derivative, a use of the derivative as therapeutic agent and a method for preparing the derivative. The benzophenone thiazole derivatives inhibit formation of microtubules and eliminate actively proliferating cells of malignant tumors to control general cell proliferation. In formula 1, R, R1 and R2 are defined as above.

Abstract: A spacer grid used for placing and supporting fuel rods in nuclear reactor fuel assemblies is disclosed. The spacer grid of this invention has a plurality of inner strips intersecting each other to form a plurality of guide tube cells and a plurality of fuel rod cells, with a plurality of mixing blades projecting upward from the inner strips at intersections of the inner strips. The spacer grid further includes a plurality of perimeter strips to encircle the intersecting inner strips. Each of the perimeter strips is fabricated with a plurality of unit intermediate strips and a plurality of unit corner strips, with a grid spring provided on each of the unit strips.

Abstract: Provided herein is an MV DRAM device capable of storing multiple value levels using an SET device. The device includes one or more word lines; one or more bitlines; a DRAM cell connected to intersections of the word lines and the bitlines; a current source transistor having a source connected to a power supply voltage and a gate and a drain connected to the bitlines; an SET (single electron transistor) device having a gate connected to the bitlines and a source connected to the ground voltage; and a transistor connected between the bitlines and the drain of the SET device, wherein the gate of the transistor is connected to the ground voltage. According to the MV DRAM device of the present invention, since two or more multiple value data are stored in a cell, it is possible to increase the storage density of the device.

Abstract: Provided herein are compositions, all related stereoisomers as well as pharmaceutically acceptable salts provided as simplified analogs of pateamine A, in which the analogs generally are devoid of the C3-amino and C5-methyl groups, also referred to as desmethyl, desamino-pateamine A. Suitable analogs provide anticancer and antiproliferative effects in vivo and in vitro by a novel drug mechanism of action described herein for pateamine A, including inhibition of eIF4A-dependent translation initiation. As with pateamine A, as described herein, suitable analogs cause cell cycle arrest or induce apoptosis in transformed cells. However, toxicity of such compounds to slow growing normal cells is low. In addition, such analogs, like pateamine A, target translation initiation factors and are useful as anticancer and antiproliferative agents in subjects in need thereof.

Abstract: Provided is a multi-valued dynamic random access memory (DRAM) cell using a single electron transistor (SET). The multi-valued DRAM cell using the SET applies different refresh signals to a load current transistor for controlling current supply to the SET and a voltage control transistor for controlling a terminal voltage of the SET and refreshes a data value stored in the SET by a predetermined period to reduce standby current and stably supply a voltage low enough to satisfy a coulomb-blockade condition to the terminal of the SET.

Abstract: Disclosed herein are novel benzophenone derivatives represented by formula I, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, a pharmacological composition containing the same, and a use of the composition as therapeutic drugs. The benzophenone derivatives have an inhibition activity of microtubule formation and can be used to treat a normal proliferative state of a malignant tumor by killing the actively proliferating cells.

Abstract: A switch circuit includes a first capacitor, a second capacitor, and a switch arrangement that is operable to connect the first capacitor and the second capacitor in series between a first node that supplies a first voltage level and a second node that supplies a second voltage level, or to disconnect the first capacitor and the second capacitor from the first node and the second node, respectively, and to cross-connect the first capacitor and the second capacitor in response to a first control signal.

Abstract: An apparatus and method for welding strap connections between inner grid straps of a spacer grid using a laser tool, and a spacer grid manufactured by the same, in which the strap connections between the inner grid straps of the spacer grid are seam-welded continuously or intermittently using the laser tool, so that the structural strength of the spacer grid is increased, a spattering phenomenon, in which a welded material is spattered during welding, is reduced, and thermal deformation is reduced. Further, fine welding is possible, and thus the welded bead of each strap connection between the inner grid straps can have a small size, and the number of welding defects can be reduced. In addition, the flow resistance of a coolant is reduced, and thereby the pressure drop of the coolant can be reduced As a result, the load on a flow pump for the coolant can be reduced, and economic efficiency and safety can be improved.