Abstract: A charged particle irradiation system is capable of shortening the irradiation time and the treatment time by performing efficient irradiation even when irregular variation occurs in the irradiation object during the gating irradiation. The extraction of the beam is stopped upon reception of a regular extraction permission end signal which is outputted based on a regular movement signal. An extractable state maintaining function operates upon the reception of the extraction permission end signal. When a preset standby time elapses without receiving an extraction permission start signal again during the standby time, the extractable state maintaining function finishes its operation and a charged particle beam generator decelerates the beam. Also, the extraction of the beam is stopped due to reception of an irregular extraction permission end signal during the irradiation. When the extraction permission start signal is received again during the standby time, the extraction of the beam is restarted.

Abstract: A structure configuring a ridge filter has line symmetry about a line vertical to a depth direction passing the center of the structure. A small structure obtained in such a way that the structure is divided by this line has a bilaterally asymmetric shape about a center line in an iterative direction, and has a point symmetric shape about an intersection between the center line in the iterative direction and the center line in the depth direction. Thicknesses in the iterative direction of an uppermost stream surface and a lowermost stream surface in the depth direction are equal to each other. The structure is configured so that a thick portion in the iterative direction of the uppermost stream surface and the lowermost stream surface is not present in the depth direction.

Abstract: A radiotherapy system acquires an image which is necessary for positioning of a patient for radiation treatment and enables grasping of a positional relationship of a target in a treatment radiation irradiated state, a radiation passing area and a critical organ. An X-ray imaging device is attached to the rotatable support device and configured to apply X-rays to the subject from plural directions while rotating around the subject to perform X-ray imaging. A target recognizing device recognizes a three-dimensional position of the target in the subject from X-ray images acquired by the X-ray imaging device; and CT image generating devices are configured to select, from the X-ray images acquired by the X-ray imaging device, the images in which the position of the target recognized by the recognizing device satisfies the treatment radiation irradiation condition for the motion tracking treatment to perform image reconstruction and generate a cone beam CT image.

Abstract: Provided is an oligonucleic acid analog which contains, as at least one structural unit thereof, a modified nucleic acid monomer compound which is a ring-open nucleoside having a cleaved carbon-carbon bond between the 2? and 3? positions and a substituent hydroxymethyl group at the 4? position. When used as siRNA, the oligonucleic acid analog exhibits superior biological stability and target gene expression inhibiting activity. The oligonucleic acid analog can be used in antisense methods, ribozyme methods, and decoy methods, etc., can be used as a nucleic acid aptamer, and can also be used as a nucleic acid probe or molecular beacon, etc., or in genetic diagnostics, etc.

Abstract: A radiotherapy control apparatus includes a fluoroscopic image acquisition unit to acquire fluoroscopic images of markers in a patient from a single fluoroscopic imaging device, a projection line calculation unit to identify projected positions of the markers on the fluoroscopic image and calculate equations of projection lines linking these projected positions and a focus position of the imaging device, an inter-marker distance acquisition unit to acquire a distance between each pair of the markers, a marker position calculation unit to calculate current positions of the markers based on the equations and the distances, and a therapeutic radiation emission determination unit to determine whether to emit therapeutic radiation based on the current positions of the markers.

Abstract: A fiber laser beam machine includes a machining head that condenses a laser beam and irradiates the laser beam on a workpiece; a fiber that guides the laser beam output from a laser oscillator to the machining head; a fiber connector that fixedly joins the fiber to the machining head; a cable holding device such as a cable bear (registered trademark) that is flexible, is in a U shape, and houses the fiber; and a fixing section that fixedly joins the cable holding device to the machining head.

Abstract: In a laser processing machine 100 including a plurality of element units containing at least a laser blower unit 3, an optical-path purge unit 24, and a temperature controlling unit 8, a measurement unit and a control unit 10 are provided. The measurement unit measures an elapsed time from a final trigger at which a laser processing operation of the laser processing machine has stopped and no user operation is applied with respect to the laser processing machine. The control unit 10 stops the element units based on the elapsed time after the final trigger, when a condition specified for each of the element units is satisfied.

Abstract: The laser machining apparatus includes a transmission fiber that transmits laser light emitted from a laser oscillator through the fiber, a machining head that emits the laser light, which is sent from the transmission fiber, vertically to a main surface of a machining object and sends reflected light, which is reflected coaxially with the laser light by the machining object, to the transmission fiber, a reflected light monitoring unit that detects a reflected light intensity of the reflected light sent from the transmission fiber, and a control device that controls the laser oscillator and the machining head, in which the control device includes a determining unit that, at a time when laser machining is started, determines whether the machining object corresponds to a machining condition or not in laser machining on the basis of the reflected light intensity.

Abstract: Agglomerated silica is obtained by mixing silica with a rosin resin to be agglomerated.

Abstract: A semiconductor laser apparatus, including: a beam divergence angle correction optical system for correcting a divergence angle of beams generated from light emitting points of a semiconductor laser bar; a beam rotation optical system for rotating the beams each having the corrected divergence angle; a wavelength dispersion optical element having a wavelength dispersion function; and a partial reflection mirror. A relative position of the beam divergence angle correction optical system with respect to the light emitting point in a divergence angle correction direction is changed for each light emitting point.

Abstract: Provided is an oligonucleic acid analog which contains, as at least one structural unit thereof, a modified nucleic acid monomer compound which is a ring-open nucleoside having a cleaved carbon-carbon bond between the 2? and 3? positions and a substituent hydroxymethyl group at the 4? position. When used as siRNA, the oligonucleic acid analog exhibits superior biological stability and target gene expression inhibiting activity. The oligonucleic acid analog can be used in antisense methods, ribozyme methods, and decoy methods, etc., can be used as a nucleic acid aptamer, and can also be used as a nucleic acid probe or molecular beacon, etc., or in genetic diagnostics, etc.

Abstract: A semiconductor laser apparatus, including: a beam divergence angle correction optical system for correcting a divergence angle of beams generated from light emitting points of a semiconductor laser bar; a beam rotation optical system for rotating the beams each having the corrected divergence angle; a wavelength dispersion optical element having a wavelength dispersion function; and a partial reflection mirror. A relative position of the beam divergence angle correction optical system with respect to the light emitting point in a divergence angle correction direction is changed for each light emitting point.

Abstract: A charged particle irradiation system is capable of shortening the irradiation time and the treatment time by performing efficient irradiation even when irregular variation occurs in the irradiation object during the gating irradiation. The extraction of the beam is stopped upon reception of a regular extraction permission end signal which is outputted based on a regular movement signal. An extractable state maintaining function operates upon the reception of the extraction permission end signal. When a preset standby time elapses without receiving an extraction permission start signal again during the standby time, the extractable state maintaining function finishes its operation and a charged particle beam generator decelerates the beam. Also, the extraction of the beam is stopped due to reception of an irregular extraction permission end signal during the irradiation. When the extraction permission start signal is received again during the standby time, the extraction of the beam is restarted.

Abstract: In the case where X-ray tubes and X-ray detectors have fixed directions (directions of irradiation and directions of detecting planes), X-ray fluoroscopy can be carried out from various directions by providing two U-shaped tracks for the X-ray tubes and the X-ray detectors, each having two straight tracks arranged opposite each other, and a curved track connected thereto. An increased number of directions for X-ray fluoroscopy can be secured by arranging a U-shaped track rail for the X-ray tubes and a U-shaped track rail for the X-ray detectors opposite each other when seen in plane view.

Abstract: A charged particle irradiation system is capable of shortening the irradiation time and the treatment time by performing efficient irradiation even when irregular variation occurs in the irradiation object during the gating irradiation. The extraction of the beam is stopped upon reception of a regular extraction permission end signal which is outputted based on a regular movement signal. An extractable state maintaining function operates upon the reception of the extraction permission end signal. When a preset standby time elapses without receiving an extraction permission start signal again during the standby time, the extractable state maintaining function finishes its operation and a charged particle beam generator decelerates the beam. Also, the extraction of the beam is stopped due to reception of an irregular extraction permission end signal during the irradiation. When the extraction permission start signal is received again during the standby time, the extraction of the beam is restarted.

Abstract: A fiber laser beam machine includes a machining head that condenses a laser beam and irradiates the laser beam on a workpiece; a fiber that guides the laser beam output from a laser oscillator to the machining head; a fiber connector that fixedly joins the fiber to the machining head; a cable holding device such as a cable bear (registered trademark) that is flexible, is in a U shape, and houses the fiber; and a fixing section that fixedly joins the cable holding device to the machining head.

Abstract: [Problem to be Solved] To provide a radiotherapy control apparatus and radiotherapy control program capable of calculating the current positions of markers implanted in a patient by means of a single fluoroscopic imaging device and reducing a radiation exposure dose inflicted on the patient by radiographic radiation used for fluoroscopic observation during radiotherapy. [Solution] The present invention includes a fluoroscopic image acquisition unit 41 adapted to acquire a fluoroscopic image of three or more markers from a single fluoroscopic imaging device 12, a projection line calculation unit 38 adapted to calculate equations of respective projection lines, an inter-marker distance acquisition unit 42 adapted to acquire each distance between each pair of the markers, a marker position calculation unit 43 adapted to calculate current positions of the respective markers, and a therapeutic radiation emission determination unit 44 adapted to determine whether to emit therapeutic radiation.

Abstract: A radiotherapy system acquires an image which is necessary for positioning of a patient for radiation treatment and enables grasping of a positional relationship of a target in a treatment radiation irradiated state, a radiation passing area and a critical organ. An X-ray imaging device is attached to the rotatable support device and configured to apply X-rays to the subject from plural directions while rotating around the subject to perform X-ray imaging. A target recognizing device recognizes a three-dimensional position of the target in the subject from X-ray images acquired by the X-ray imaging device; and CT image generating devices are configured to select, from the X-ray images acquired by the X-ray imaging device, the images in which the position of the target recognized by the recognizing device satisfies the treatment radiation irradiation condition for the motion tracking treatment to perform image reconstruction and generate a cone beam CT image.

Abstract: A charged particle irradiation system is capable of shortening the irradiation time and the treatment time by performing efficient irradiation even when irregular variation occurs in the irradiation object during the gating irradiation. The extraction of the beam is stopped upon reception of a regular extraction permission end signal which is outputted based on a regular movement signal. An extractable state maintaining function operates upon the reception of the extraction permission end signal. When a preset standby time elapses without receiving an extraction permission start signal again during the standby time, the extractable state maintaining function finishes its operation and a charged particle beam generator decelerates the beam. Also, the extraction of the beam is stopped due to reception of an irregular extraction permission end signal during the irradiation. When the extraction permission start signal is received again during the standby time, the extraction of the beam is restarted.

Abstract: A tri-axially orthogonal gas laser device in which an optical axis of an optical resonator, a direction in which a laser gas is supplied into the optical resonator, and a direction of discharge for exciting the laser gas are mutually orthogonal to one another, the device including: an exciting unit including a blower supplying the laser gas in ?X direction to the optical axis of the optical resonator, and a discharge electrode pair which is shifted on a gas upstream side with respect to the optical axis; and an exciting unit including a blower for supplying the laser gas in +X direction to the optical axis of the optical resonator, and a discharge electrode pair which is shifted on a gas upstream side with respect to the optical axis