Abstract: A method of regio-selectively synthesizing an imidazo-pyrimidine compound of formulae (XXa) or (XXb) comprising a step of coupling a first compound of formula XX-P1a or XX-P1b with a second compound of formula XX-P2 This annulation reaction between ?-ethoxy acrylamides and phosphorylated aminoimidazoles to furnish imidazo[1,2-a]pyrimidin-amines relies on steering effects from endocyclic and exocyclic phosphorylated aminoimidazoles. The reaction furnishes either 2-amino or 4-amino constitutional isomers of imidazo[1,2-a]pyrimidines with good yields and ranges of 90:10-99:1 regio-selectivity. The reaction is useful in the synthesis of various tracer molecules used in the study of neurological conditions such as where R3 and R4 together with the imidazole ring atoms to which they are bonded form a phenyl ring and the products are substituted benzimidazopyrimidines.

Abstract: A method includes extracting data from a log file including location information and identification information. The method also includes normalizing the data and processing the normalized data to determine at least one of the quantity of data points corresponds to the location information. The method further includes processing graphical background data to determine a plurality of available zoom levels and processing the normalized data with respect to the graphical background data and each zoom level of the plurality of available zoom levels to determine a quantity of data points within a predetermined distance from a reference position in the graphical background data. The method additionally includes causing a graphical user interface to be output including a graphical representation of the graphical background data at a selected zoom level of the plurality of available zoom levels and one or more icons displayed over the graphical representation of the graphical background data.

Abstract: A tub is configured to contain a supply of water and is configured to be inserted into a chamber of a humidifier. The tub includes a tub base configured to contain the supply of water. The tub also includes a tub lid and a flow plate provided between the tub base and the tub lid. The flow plate includes a water level indicator configured to indicate a level of the supply of water in the tub base. In addition, the water level indicator includes a generally rectangular portion and a generally triangular portion.

Abstract: Antibodies, and antigen-binding fragments thereof, that specifically bind to Cluster of Differentiation 1a (CD1a) are provided. Embodiments include uses, and associated methods of using the antibodies, and antigen-binding fragments thereof.

Abstract: A capsule containing a substance for the preparation of a potable beverage. The capsule comprises an aluminum capsule body having a side wall and an outwardly extending flange and a sealing member at the outwardly extending flange for providing a fluid sealing contact with an enclosing member of a beverage preparation device. The beverage preparation device comprises an annular element having a free contact end which may be provided with a plurality of radially extending open grooves. The sealing member is integral with the outwardly extending flange and comprises at least one projection projecting from the outwardly extending flange. The projection comprising a projection top and is configured such that its projection top exerts a radial force on the free contact end of the annular element if the capsule is positioned in the enclosing member of the beverage preparation device and the enclosing member is closed by means of a closing member of the beverage preparation device.

Abstract: A body-worn tracking device (BWTD) includes a global navigation satellite system (GNSS) device, at least one motion sensor, at least one processor, and at least one memory device. The at least one memory device includes instructions that, when executed by the at least one processor, cause the at least one processor to determine, based on data generated by the at least one motion sensor, a net distance between the last known location of the BWTD and a current location of the BWTD. The instructions further cause the at least one processor to determine, based on the net distance, whether the BWTD is within a bounded area that includes the last known location; and responsive to determining that BWTD is not within the bounded area, output an indication that the BWTD is not within the bounded area.

Abstract: A system for heating and frothing a beverage includes a device for preparing a beverage and a wand (12). The device has a wand holder (31) in which the wand is removably mountable to hold the wand in an operative position and a steam nozzle (15) operably connectable with a source of steam. The steam nozzle (15) is movable between a wand insertion position spaced from the wand holder to permit the wand to be inserted into or removed from the wand holder and a wand engagement position in which it operatively engages with an inlet end of the wand. The device has an actuator arrangement (60) operative to move the steam nozzle between said wand insertion and wand engagement positions and a control system for regulating actuation of the actuator arrangement.

Abstract: The system and method of the present invention expand/enhance modeling for credit risks scores. The expanded modeling system and methods discussed herein identify new credit risk related attributes using limited and/or unconventional credit data. In an aspect, the system and method enhance performance definitions to capture incremental insight, expanding the applicable consumer segments previously inaccessible.

Abstract: An invention as provided is a method of preparing a beverage or beverage extract comprising steps of: a. providing an extraction chamber comprising an extractable beverage material, a liquid inlet and a liquid outlet, and b. conveying a liquid into the chamber via the inlet and at least a portion of the liquid out of the chamber via the outlet, and c. conveying at least a portion of the liquid that has exited the chamber from step b) back into the chamber via the outlet and conveying at least a portion of the liquid out of the chamber via the inlet. wherein steps b) and c) are repeated at least twice, and wherein at least a portion of the liquid conveyed into the chamber in at least one subsequent step b), in addition to the first step b), is conveyed into the chamber for the first time.

Abstract: The present invention relates a molded composite material and a method and process for creating the composite material from either recycled low grade mixed glass cullet or new glass. The composite material including; crushed glass; one or more aluminium compounds selected from oxide and hydrate at combined 0.40%-0.78% weight per weight of the glass; oxides of silicon, boron, sodium, calcium and potassium at combined 1.27%-1.90% weight per weight of the glass; zirconium silicate at 0.48%-1.3% weight per weight of the glass; and optionally tin oxide at 0%-0.45% weight per weight of the glass. The composite of the present invention can be used for making tiles, bench tops, work surfaces or other similar types of building products. The use of low grade mixed glass can also help reduce the amount of used glass being dumped in landfill or used in other low value enterprises such as providing highway aggregate or landfill cover.

Abstract: A method of forming a cross-car beam is provided. A composite is melted to form a viscous polymer. The polymer is injected into a mold. Pressurized fluid is injected into the mold to evacuate a portion of the viscous polymer from the mold and to form a channel therethrough. The remaining viscous polymer is cooled within the mold to form a cross-car beam.

Abstract: Example techniques of this disclosure are directed determining one or more values that represent a monitoring attribute for one or more body-worn tracking devices (BWTDs). In some instances, the techniques include determining a compliance metric that represents a level of compliance for at least one offender. That is, the compliance metric may be a quantitative value that represents whether a user wearing BWTD is complying with established rules or desired behaviors.

Abstract: A thermal management system for a computing device includes an immersion tank with a cooling fluid therein, a computing device positioned in the cooling fluid in the immersion tank, and a thermal block positioned in the cooling fluid in the immersion tank. The computing device heats the cooling fluid, and the thermal block is configured to receive heat from the cooling fluid. The thermal block includes a fluid management feature to direct flow of the cooling fluid relative to the thermal block and computing device.

Abstract: A solar tracker system comprising one or more tracker rotation control systems that include: a curved gear plate; and a locking element configured to lock the solar tracker system in a first configuration.

Abstract: An apparatus and method are provided for performing bit permutation operations. The apparatus has an interface for receiving an input data operand and a control operand. The input data operand comprises one or more data elements, each data element comprising a plurality of bits, and the control operand provides control information identifying bit permutations required when performing a given bit permutation operation on each data element. The bit permute circuitry treats the input data operand as a plurality of fixed size data portions, each data element comprising one or more of the data portions with the number being dependent on the data element size. The bit permute circuitry performs bit permutation operations on each data portion of the input data operand, using the control information provided for that data portion, generating, for each data portion, at least one intermediate result.

Abstract: A capsule containing a substance for the preparation of a potable beverage. The capsule comprises an aluminum capsule body having a side wall and an outwardly extending flange and a sealing member at the outwardly extending flange for providing a fluid sealing contact with an enclosing member of a beverage preparation device. The beverage preparation device comprises an annular element having a free contact end which may be provided with a plurality of radially extending open grooves. The sealing member is integral with the outwardly extending flange and comprises at least one projection projecting from the outwardly extending flange. The projection comprising a projection top and is configured such that its projection top exerts a radial force on the free contact end of the annular element if the capsule is positioned in the enclosing member of the beverage preparation device and the enclosing member is closed by means of a closing member of the beverage preparation device.

Abstract: An apparatus and method are provided for performing bit permutation operations. The apparatus has an interface for receiving an input data operand and a control operand. The input data operand comprises one or more data elements, each data element comprising a plurality of bits, and the control operand provides control information identifying bit permutations required when performing a given bit permutation operation on each data element. The bit permute circuitry treats the input data operand as a plurality of fixed size data portions, each data element comprising one or more of the data portions with the number being dependent on the data element size. The bit permute circuitry performs bit permutation operations on each data portion of the input data operand, using the control information provided for that data portion, generating, for each data portion, at least one intermediate result.

Abstract: A system for tracking a location of a body-worn tracking device (BWTD) includes a global navigation satellite system (GNSS) component, one or more sensors, one or more processors, and a memory device. The memory device includes instructions that, when executed by the one or more processors, cause the one or more processors to determine whether a current location of the BWTD can be determined using the GNSS component. The instructions also cause the one or more processors to determine, based in part on the activity of the wearer of the BWTD and based on a determination that the current location of the BWTD cannot be determined using the GNSS component, whether to perform an action. The instructions also cause the one or more processors to perform the action in response to a determination to perform the action.

Abstract: The disclosed technology is generally directed to fuel cells. In one example of the technology, a fuel cell stack that includes an anode and a cathode causes a load to be driven. A control subsystem is measures at least one characteristic associated with the load, and to provide at least one control signal based, at least in part, on the at least one characteristic. An oxidizing agent input subsystem provides an oxidizing agent to the cathode of the fuel cell stack. A fuel input subsystem provides gaseous fuel to the anode of the fuel cell stack. The fuel input subsystem includes a fuel pump that is arranged to pump the gaseous fuel into the fuel input subsystem. A fuel-side high-speed valve adjusts mass flow of the gaseous fuel to the cathode of the fuel cell stack based on at least a first control signal of the at least one control signal.