Patents by Inventor Nicholas I. Carruthers

Nicholas I. Carruthers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serotonin receptor modulators
    Patent number: 9981909
    Abstract: Certain biphenyic compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: May 29, 2018
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Wenying Chai, Jill A. Jablonowski, Chandravadan R. Shah, Brock T. Shireman, Devin M. Swanson, Vi Tran, Victoria Wong
  • SEROTONIN RECEPTOR MODULATORS
    Publication number: 20160046574
    Abstract: Certain biphenyic compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Application
    Filed: October 28, 2015
    Publication date: February 18, 2016
    Inventors: Nicholas I. Carruthers, Wenying Chai, Jill A. Jablonowski, Chandravadan R. Shah, Brock T. Shireman, Devin M. Swanson, Vi Tran, Victoria Wong
  • Modulators of serotonin receptors
    Patent number: 8957059
    Abstract: Certain biphenyl compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: February 17, 2015
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Jill A. Jablonowski, Brock T. Shireman, Vi T. Tran
  • 2-aminopyrimidine compounds as serotonin receptor modulators
    Patent number: 8829011
    Abstract: Certain 2-aminopyrimidine compounds of formula (I) are serotonin receptor modulators useful in the treatment of diseases mediated by serotonin receptors.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: September 9, 2014
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Gregor J. MacDonald, Brock T. Shireman, Vi T. Tran
  • MODULATORS OF SEROTONIN RECEPTORS
    Publication number: 20140038934
    Abstract: Certain biphenyl compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Application
    Filed: October 10, 2013
    Publication date: February 6, 2014
    Applicant: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Jill A. Jablonowski, Shireman T. Brock, Vi T. Tran
  • SEROTONIN RECEPTOR MODULATOR
    Publication number: 20140038943
    Abstract: Certain biphenyic compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Application
    Filed: October 10, 2013
    Publication date: February 6, 2014
    Applicant: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Wenying Chai, Jill A. Jablonowski, Chandravadan R. Shah, Brock T. Shireman, Devin M. Swanson, Vi Tran, Victoria Wong
  • Serotonin receptor modulators
    Patent number: 8642583
    Abstract: The biphenyic compounds of formula (I) are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: February 4, 2014
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Wenying Chai, Jill A. Jablonowski, Chandravadan R. Shah, Brock T. Shireman, Devin M. Swanson, Vi T. Tran, Victoria D. Wong
  • Modulators of serotonin receptor
    Patent number: 8575364
    Abstract: Certain biphenyl compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: November 5, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Brock T. Shireman, Vi T. Tran, Jill A. Jablonowski
  • HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS
    Publication number: 20120321559
    Abstract: Certain hexahydro-pyrrolo-isoquinoline compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
    Type: Application
    Filed: August 24, 2012
    Publication date: December 20, 2012
    Inventors: Richard Apodaca, Ann J. Barbier, Nicholas I. Carruthers, Leslie A. Gomez, John M. Keith, Timothy W. Lovenberg, Ronald L. Wolin
  • Hexahydro-pyrrolo-isoquinoline compounds
    Patent number: 8273762
    Abstract: Certain hexahydro-pyrrolo-isoquinoline compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: September 25, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Richard Apodaca, Ann J. Barbier, Nicholas I. Carruthers, Leslie A. Gomez, John M. Keith, Timothy W. Lovenberg, Ronald L. Wolin
  • Substituted pyrrolidine amides as modulators of the histamine Hreceptor
    Patent number: 8236792
    Abstract: Certain substituted pyrrolidine amide compounds are histamine H3 receptor modulators useful in the treatment of histamine H3 receptor-mediated diseases.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: August 7, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I Carruthers, Michael A. Letavic, Kiev S. Ly, Neelakandha S. Mani, Daniel J. Pippel, Chandravadan R. Shah, Akinola Soyode-Johnson, Emily M. Stocking, Lana Young
  • Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor
    Patent number: 8183239
    Abstract: The invention provides novel non-peptidic NPY Y2 receptor inhibitors useful in treating or preventing: anxiolytic disorders or depression; injured mammalian nerve tissue; conditions responsive to treatment through administration of a neurotrophic factor; neurological disorders; bone loss; substance related disorders; sleep/wake disorders; cardiovascular disease; obesity; or an obesity-related disorder. Compounds of the invention are also useful in modulating endocrine functions, particularly endocrine functions controlled by the pituitary and hypothalamic glands, and are therefore useful in the treatment or prevention of inovulation and infertility.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: May 22, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Pascal Bonaventure, Nicholas I. Carruthers, Wenying Chai, Curt A. Dvorak, Jill A. Jablonowski, Dale A. Rudolph, Mark Seierstad, Chandravadan R. Shah, Devin M. Swanson, Victoria D. Wong
  • Cyclopropyl amines as modulators of the histamine Hreceptor
    Patent number: 8026242
    Abstract: Certain cyclopropyl amines are histamine H3 modulators useful in the treatment of histamine H3 receptor mediated diseases.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: September 27, 2011
    Inventors: Nicholas I. Carruthers, Michael A. Letavic
  • MODULATORS OF SEROTONIN RECEPTOR
    Publication number: 20110207709
    Abstract: Certain biphenyl compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Application
    Filed: October 29, 2009
    Publication date: August 25, 2011
    Inventors: Nicholas I. Carruthers, Brock T. Shireman, Vi T. Tran
  • 2-AMINOPYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS
    Publication number: 20110207717
    Abstract: Certain 2-aminopyrimidine compounds are serotonin receptor modulators useful in the treatment of diseases mediated by serotonin receptors.
    Type: Application
    Filed: October 29, 2009
    Publication date: August 25, 2011
    Inventors: Nicholas I. Carruthers, Gregor J. MacDonald, Brock T. Shireman, Vi T. Tran
  • SEROTONIN RECEPTOR MODULATORS
    Publication number: 20110207714
    Abstract: The biphenyic compounds of formula (I) are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Application
    Filed: October 29, 2009
    Publication date: August 25, 2011
    Inventors: Nicholas I. Carruthers, Brock T. Shireman, Vi T. Tran, Victoria D. Wong, Jill A. Jablonowski, Wenying Chai
  • CYCLOPROPYL AMINES AS MODULATORS OF THE HISTAMINE H3 RECEPTOR
    Publication number: 20110136797
    Abstract: Certain cyclopropyl amines are histamine H3 modulators useful in the treatment of histamine H3 receptor mediated diseases.
    Type: Application
    Filed: February 16, 2011
    Publication date: June 9, 2011
    Inventors: Nicholas I. Carruthers, Michael A. Letavic
  • Isoxazole compounds as histamine Hmodulators
    Patent number: 7947718
    Abstract: Certain isoxazole compounds are histamine H3 modulators useful in the treatment of histamine H3 receptor mediated diseases.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: May 24, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Chandravadan R. Shah, Devin M. Swanson
  • Fused heterocyclic compounds
    Patent number: 7897771
    Abstract: Certain fused pyrrole- and pyrazole-containing heterocyclic compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: March 1, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Nicholas I. Carruthers, Wenying Chai, Xiaohu Deng, Curt A. Dvorak, Annette K. Kwok, Jimmy T. Liang, Neelakandha Mani, Dale A. Rudolph, Victoria D. Wong
  • FUSED HETEROCYCLIC COMPOUNDS
    Publication number: 20110040088
    Abstract: Certain fused pyrrole- and pyrazole-containing heterocyclic compounds are serotonin modulators useful in the treatment of serotonin-mediated diseases.
    Type: Application
    Filed: October 25, 2010
    Publication date: February 17, 2011
    Inventors: Nicholas I. Carruthers, Wenying Chai, Xiaohu Deng, Curt A. Ovorak, Annette K. Kwok, Jimmiy T. Liang, Neelakandha Mani, Dale A. Rudolph, Victoria D. Wong