Patents by Inventor Nicholas Simone

Nicholas Simone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8140500
    Abstract: A system is provided wherein spectrometer measurements, and/or measurements from other analytical instruments, are transmitted to a processing station which determines the component substances of the sample(s) subjected to the measurements. The names of the component substances are then inserted into database search queries related to matters such as handling precautions, causes/sources of the substances, remedies and neutralizing agents for the substances, regulations related to the substances, etc. The results of the search queries are then provided to the personnel who made the measurements, preferably wirelessly and almost immediately after the measurements were made. The system therefore provides nearly immediate guidance as to what substances are present and how to handle them, which can be useful for inexperienced personnel in hazardous response, contraband detection, industrial process control, and other situations.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: March 20, 2012
    Assignee: Thermo Electron Scientific Instruments LLC
    Inventors: Jerome J. Workman, Stephen R. Lowry, Nicholas Simon Nunn, Kathleen J. Schulting
  • Publication number: 20120058123
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: October 12, 2011
    Publication date: March 8, 2012
    Applicant: PANMIRA PHARMACEUTICALS, LLC.
    Inventors: John Howard HUTCHINSON, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang, Deborah Volkots
  • Publication number: 20120059055
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 8, 2012
    Applicant: PANMIRA PHARMACEUTICALS, LLC
    Inventors: John Howard HUTCHINSON, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang
  • Publication number: 20120027842
    Abstract: Described herein are topical formulations for administration to an eye, wherein the formulation is administered to treat ophthalmic diseases, disorders, or conditions. A topical formulation for administration to an eye disclosed herein comprises a therapeutically-effective amount of a FLAP inhibitor compound formulated for topical administration to the eye.
    Type: Application
    Filed: December 21, 2009
    Publication date: February 2, 2012
    Applicant: Amira Pharmaceuticals, Inc.
    Inventors: John Howard Hutchinson, Jillian F. Evans, Nicholas Simon Stock
  • Publication number: 20120022119
    Abstract: Described herein are heteroaryl compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the heteroaryl compounds described. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: November 16, 2009
    Publication date: January 26, 2012
    Applicant: Amira Pharmaceuticals, Inc.
    Inventors: John Howard Hutchinson, Nicholas Simon Stock, Jeffrey Roger Roppe, Brian Andrew Stearns, Timothy Parr
  • Publication number: 20110319445
    Abstract: Described herein are heteroaryl compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the heteroaryl compounds described. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: October 1, 2009
    Publication date: December 29, 2011
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Nicholas Simon Stock, Jeffrey Roger Roppe, Deborah Volkots
  • Publication number: 20110312974
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: September 28, 2009
    Publication date: December 22, 2011
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Nicholas Simone Stock, Yen Pham Truong, Jeffrey Roger Roppe, Deborah Volkots, Jill Melissa Scott, Timothy Andrew Parr, Bowei Wang, Thomas Jon Seiders, Ryan Clark, Heather Renee Coate
  • Publication number: 20110311305
    Abstract: A transfer device includes a first portion having a first portion flange and a second portion having a second portion flange. The device also includes one or more isolating members disposed at least partially within the second portion flange and at least partially between the first portion flange and the second portion flange, the one or more isolating members electrically isolating the first portion from the second portion. The device also includes a fastener passing through one of the one or more isolating members, the first portion flange and the second portion flange and holding the first portion flange and the second portion flange in a fixed relationship to one another.
    Type: Application
    Filed: June 18, 2010
    Publication date: December 22, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Ronald Ralph Cairo, Nicholas Simon Graham
  • Publication number: 20110311304
    Abstract: A coupling includes a first portion configured for connection to a first shaft and having a first portion flange and a second portion configured for connection to a second shaft and having a second portion flange. The coupling also includes an isolating member disposed between the first portion flange and the second portion flange and that is formed of ceramic and electrically isolates the first portion from the second portion. The coupling also includes one or more connecting members passing through the first portion flange, the second portion flange, and the isolating member and holding the first portion flange and the second portion flange in a fixed relationship to one another.
    Type: Application
    Filed: June 18, 2010
    Publication date: December 22, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Nicholas Simon Graham, Ronald Ralph Cairo, Thomas Joseph Farineau, William Patrick Rusch
  • Patent number: 8067445
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: November 29, 2011
    Assignee: Panmira Pharmaceuticals, LLC
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang, Deborah Volkots
  • Patent number: 8049015
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: November 1, 2011
    Assignee: Panmira Pharmaceuticals, LLC
    Inventors: John Howard Hutchinson, Nicholas Simon Stock, Jeffrey Roger Roppe, Jill Melissa Scott, Brian Andrew Stearns, Yen Pham Truong, Deborah Volkots, Timothy Parr
  • Patent number: 8006983
    Abstract: A method for assembling a seal assembly is provided. The method includes coupling a first ring within a vessel, coupling a second ring within the vessel, and coupling a first seal layer between the first ring and the second ring such that the first seal layer contacts at least the first ring.
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: August 30, 2011
    Assignee: General Electric Company
    Inventors: Steven Craig Russell, Nicholas Simon Graham, Kelsey Elizabeth Beach, James Michael Storey
  • Patent number: 7977359
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: July 12, 2011
    Assignee: Amira Pharmaceuticals, Inc.
    Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Brian Andrew Stearns, Jeffrey Roger Roppe, Yiwei Li, Jasmine Eleanor Zunic, Jeannie M. Arruda, Nicholas Simon Stock, Mustapha Haddach
  • Publication number: 20110160249
    Abstract: A pharmaceutically acceptable salt comprising 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxy-pyridin-3-yl)-benzyl]-5-(5-methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionate as the anion and a cation selected from Na+, K+, Li+, Ca2+, NH4+, the protonated form of dicyclohexylamine, the protonated form of N-methyl-D-glucamine, the protonated form of tris(hydroxymethyl)methylamine, the protonated form of arginine, and the protonated form of lysine is disclosed, along with formulations and methods of using the same.
    Type: Application
    Filed: May 22, 2009
    Publication date: June 30, 2011
    Inventors: Kevin Murray Schaab, Christopher David King, Nicholas Simon Stock
  • Publication number: 20110118315
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Application
    Filed: January 24, 2011
    Publication date: May 19, 2011
    Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Yiwei Li, Jasmine Eleanor Zunic, Jeannie M. Arruda, Nicholas Simon Stock, Brian Andrew Stearns, Mustapha Haddach, Jeffrey Roger Roppe
  • Publication number: 20110098352
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: January 29, 2009
    Publication date: April 28, 2011
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang
  • Publication number: 20110082181
    Abstract: Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
    Type: Application
    Filed: October 1, 2010
    Publication date: April 7, 2011
    Applicant: Amira Phamaceuticals, Inc.
    Inventors: Thomas Jon SEIDERS, Lucy Zhao, Jeannie M. Arruda, Brian Andrew Stearns, Yen Pham Truong, Jill Melissa Scott, John Howard Hutchinson, Nicholas Simon Stock, Deborah Volkots
  • Publication number: 20110048411
    Abstract: A point focus thin film Fresnel lens (15; 25) has an inner, substantially flat region (8; 22), and an outer region (9; 23), the outer region projecting outwardly from the inner region and at a substantial angle away from the plane of the inner region. In one embodiment the lens is in the form of a truncated cone (15) with a circular inner region as its apex, hi another embodiment the lens is in the form of a dome (25) and the outer region is formed by joining together segments (23) extending radially from a circular central region (22).
    Type: Application
    Filed: February 23, 2009
    Publication date: March 3, 2011
    Applicant: MICROSHARP CORPORATION LIMITED
    Inventor: Nicholas Simon Walker
  • Patent number: 7895529
    Abstract: A system and method for retrieving, storing and displaying featured content. In one embodiment, featured content is queried from a database storing a list of featured content items. The featured content items stored in the database may include any type of data, such as text data, hyperlink text data, markup document data, computer code, or other types or combinations of data related to a particular topic. Responsive to the query, a set of featured content items is stored in a cache file. A predetermined number of featured content items stored in the cache file are selected and stored in a system registry. Upon receipt of a display command, featured content items are read from the system registry and displayed on an interface. The displayed featured content items can be used to display hyperlinks, announcements, or other information, without inhibiting the efficiency of the boot process of a software application.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: February 22, 2011
    Assignee: Microsoft Corporation
    Inventors: Nicholas Simons, Matthew Charles Gauthier, Alberto Swett, Mitali Madhumita Pattnaik, Christopher Todd Seitzinger, Andrew Kwatinetz, Glenn L. Frankel
  • Publication number: 20110039852
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: January 29, 2009
    Publication date: February 17, 2011
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang, Deborah Volkots