Patents by Inventor Nicholas Simone

Nicholas Simone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080227807
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Application
    Filed: June 2, 2008
    Publication date: September 18, 2008
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John H. HUTCHINSON, Petpiboon Peppi PRASIT, Mark MORAN, Jillian F. EVANS, Jasmine Eleanor ZUNIC, Nicholas Simon STOCK
  • Publication number: 20080204322
    Abstract: Apparatus for determining positional information relating to an object, comprising: means for receiving, comprising a plurality of receiving elements; detection means for detecting signals received at the receiving elements and for generating output signals representative of the received signals; and processing means operable to apply, for each receiving element, a process to the output signal generated from the signal received at that receiving element separately from any output signal generated from a signal received at any other receiving element, so as to obtain a respective value of a parameter representative of the signal received at that receiving element, the processing means being further operable to compare the values of the parameter thus obtained so as to, obtain positional information relating to the object.
    Type: Application
    Filed: November 3, 2004
    Publication date: August 28, 2008
    Inventors: Gordon Kenneth Andrew Oswald, Alexandra Joanna Geoghegan, Charles Peter Bell, Nicholas Simon Russ, Mario Del Mistro, Michael Hugh Burchett, Desmond Keith Phillips, Vincent Arne Utsi
  • Patent number: 7405302
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Grant
    Filed: October 4, 2006
    Date of Patent: July 29, 2008
    Assignee: Amira Pharmaceuticals, Inc.
    Inventors: John H. Hutchinson, Petpiboon Peppi Prasit, Mark Moran, Jillian F. Evans, Jasmine Eleanor Zunic, Nicholas Simon Stock
  • Patent number: 7332516
    Abstract: The present invention encompasses compounds of Formula I (I) or pharmaceutically acceptable salts thereof, wherein A is the base molecule of a propionic acid or acetic acid NSAID, or a derivative thereof, X is —CO2H, 1H-tetrazol-5-yl or 2H-tetrazol-5-yl and R1 and R2 are each independently selected from the group consisting of: C1-6alkyl and C3-6cycloalkyl, as well as pharmaceutical composition comprising said compounds and methods of using said compounds. The compounds of the present invention lower the level of A?42 and are therefore useful for preventing, delaying or reversing the progression of Alzheimer's Disease.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: February 19, 2008
    Assignee: Merck + Co., Inc.
    Inventors: Benito Munoz, Petpiboon Prasit, Nicholas Simon Stock
  • Patent number: 7228214
    Abstract: A method and path planner for planning a path of a vehicle comprising a perimeter training module for identifying a border of a region associated with a work area. A definer for defining a reference row having a reference path that tracks at least a majority of the border. A generator generates tracking rows that track the reference row. The tracking rows comprise at least one inner tracking row and an outer tracking row. Each inner tracking row having at least one inner curve with a lesser radius than an outer tracking row having a corresponding outer curve with a greater radius.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: June 5, 2007
    Assignee: Deere & Company
    Inventors: Nicholas Simon Flann, Shane Lynn Hansen, Sarah Ann Gray
  • Patent number: 7216033
    Abstract: In accordance with one embodiment of the invention, a path planner and method for planning a path of a vehicle defines a reference row having a reference contour in a work area. A representation of the defined reference row is established. The defined reference row comprises a curved component, a generally linear component, or both. A generator generates one or more contour rows with a tracking contour that tracks or mirrors the reference contour based on a vehicular width and a radius difference parameter associated with the curved component. The contour rows are generated by a translation technique for the generally linear component and a radius modification technique for the curved component.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: May 8, 2007
    Assignee: Deere & Company
    Inventors: Nicholas Simon Flann, Shane Lynn Hansen, Sarah Ann Gray
  • Publication number: 20070027830
    Abstract: A user may provide feedback about content to express satisfaction or dissatisfaction with an application. Data associated with the user's location, the feedback, and the content is processed to provide a content author with information about how the content may be improved to increase customer satisfaction. The content author reviews the information and may modify the content or develop new content based on the information.
    Type: Application
    Filed: July 29, 2005
    Publication date: February 1, 2007
    Applicant: Microsoft Corporation
    Inventors: Nicholas Simons, Christopher Brown, Gregory Koehler, Nancy Jacobs, Robert Ashby
  • Patent number: 7110881
    Abstract: A perimeter training module establishes a perimeter path plan of a vehicle including a defined perimeter. A region-filling module establishes a region-filling path plan of the vehicle within the defined perimeter. A point-to-point planning module establishes a point-to-point path plan of a vehicle including a segment of at least one of the region-filling path plan and the perimeter path plan. The path planner forms a preferential composite path plan based on the established perimeter path plan, the region-filling plan, and the point-to-point path plan.
    Type: Grant
    Filed: October 7, 2003
    Date of Patent: September 19, 2006
    Assignee: Deere & Company
    Inventors: Sarah Ann Gray, Shane Lynn Hansen, Nicholas Simon Flann
  • Patent number: 7079943
    Abstract: A path planner and a method for determining a path for a vehicle comprises defining a starting point for the vehicle. A termination point is defined. An obstacle detector detects one or more obstacles in a work area between the starting point and the termination point. A boundary zone is defined about each corresponding obstacle. Candidate paths are identified between the starting point and the termination point. Each candidate path only intersects each boundary zone once for each corresponding obstacle. An economic cost is estimated for traversing each candidate path or a portion thereof between the starting point and the termination point. A preferential path is selected from the identified candidate paths based on the preferential path being associated with a lowest estimated economic cost.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: July 18, 2006
    Assignee: Deere & Company
    Inventors: Nicholas Simon Flann, Shane Lynn Hansen, Sarah Ann Gray
  • Publication number: 20060129931
    Abstract: An integrated help content viewer (user interface) is provided that gives a consistent user interface across multiple applications and that smoothly transitions between offline and online help content sources. A single client-side help content viewer is provided that is displayed over or adjacent to a given application user interface (e.g., word processor work space) for allowing a query of offline or online help content associated with a given topic. The help content viewer may be pinned to a user interface associated with a given application so that the help content viewer remains in a position above the user interface even if a user interface of a different application is launched.
    Type: Application
    Filed: December 10, 2004
    Publication date: June 15, 2006
    Applicant: Microsoft Corporation
    Inventors: Nicholas Simons, John Beswetherick, Irfaan Chaudhry, Tracy Ferrier, Matthew Gauthier, Stephen Kincaid, Eric Lawrence, Kent Lowry, Jennifer Sadler, Joel Wiljanen
  • Patent number: 7010425
    Abstract: A method for planning a path for a vehicle comprises creating a travel row transparency over a mapped area. The travel row transparency comprises one or more travel rows are split into travel row sections defined by intersecting the travel row with a map object (e.g., a boundary of mapped area). Partition nodes are generated from the travel row sections. The partition nodes or partition edges are linked together to form a potential drivable path consistent with user input and vehicular constrains. An efficient ordering of the partition nodes are determined consistent with the user input. A path is generated by looping through the ordered partition nodes in the determined efficient order.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: March 7, 2006
    Assignee: Deere & Company
    Inventors: Sarah Ann Gray, Shane Lynn Hansen, Nicholas Simon Flann
  • Patent number: 6934615
    Abstract: A system and method for determining a path plan for a vehicle includes organizing a work area into partition areas based on at least one of an obstacle, a concavity, and an exclusion area associated with a work area. An external cost indicator is established for indicating the economic cost corresponding to the vehicle traversing from one partition area to another partition area for each possible permutation or potential combination of successive partition areas. The established external cost indicators are searched to determine a preferential order of traversing the partition areas. A preferential path plan is determined based on the internal path plan of each partition and a transfer path plan of transferring from a prior partition to a latter partition until each partition in the work area is traversed.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: August 23, 2005
    Assignee: Deere & Company
    Inventors: Nicholas Simon Flann, Sarah Ann Gray, Shane Lynn Hansen
  • Patent number: 6907336
    Abstract: A border of a designated area is defined within a work area. A designated axis is determined for the designated area. A series of generally parallel rows are aligned consistent with a travel axis having a known alignment with respect to the designated axis. One of the generally parallel rows is aligned as a starting row. The vehicle is pointed in a starting direction along or generally parallel to the travel axis. The vehicle engages in a turn path segment after an end of the starting row to move the vehicle at least somewhat perpendicular to the travel axis between the starting row and a next row. A turn path segment has a turn radius greater than or equal to a minimum turning radius of the vehicle, where the starting row and the next row are spatially separated by a multiple of effective vehicular implement widths less an overlap allowance. The turn path segment is defined so as to skip one or more intervening parallel rows between the starting row and the next row.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: June 14, 2005
    Assignee: Deere & Company
    Inventors: Sarah Ann Gray, Shane Lynn Hansen, Nicholas Simon Flann
  • Patent number: 6836879
    Abstract: An object oriented operating system handles all objects related to text strings as belonging to one of three classes, in which each class performs a different function and at least one such class is modified to do so in a way that reduces code and cycle overhead. This reduces executable code overhead to minimise the amount of memory required, and allows execution in a minimum number of cycles to minimise power consumption. The operating system is particularly well suited to ROM based mobile computing devices.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: December 28, 2004
    Assignee: Symbian Limited
    Inventor: Nicholas Simon Myers
  • Publication number: 20040193349
    Abstract: A system and method for determining a path plan for a vehicle includes organizing a work area into partition areas based on at least one of an obstacle, a concavity, and an exclusion area associated with a work area. An external cost indicator is established for indicating the economic cost corresponding to the vehicle traversing from one partition area to another partition area for each possible permutation or potential combination of successive partition areas. The established external cost indicators are searched to determine a preferential order of traversing the partition areas. A preferential path plan is determined based on the internal path plan of each partition and a transfer path plan of transferring from a prior partition to a latter partition until each partition in the work area is traversed.
    Type: Application
    Filed: May 28, 2003
    Publication date: September 30, 2004
    Inventors: Nicholas Simon Flann, Sarah Ann Gray, Shane Lynn Hansen
  • Publication number: 20040193348
    Abstract: A border of a designated area is defined within a work area. A designated axis is determined for the designated area. A series of generally parallel rows are aligned consistent with a travel axis having a known alignment with respect to the designated axis. One of the generally parallel rows is aligned as a starting row. The vehicle is pointed in a starting direction along or generally parallel to the travel axis. The vehicle engages in a turn path segment after an end of the starting row to move the vehicle at least somewhat perpendicular to the travel axis between the starting row and a next row. A turn path segment has a turn radius greater than or equal to a minimum turning radius of the vehicle, where the starting row and the next row are spatially separated by a multiple of effective vehicular implement widths less an overlap allowance. The turn path segment is defined so as to skip one or more intervening parallel rows between the starting row and the next row.
    Type: Application
    Filed: May 27, 2003
    Publication date: September 30, 2004
    Inventors: Sarah Ann Gray, Shane Lynn Hansen, Nicholas Simon Flann
  • Publication number: 20030056788
    Abstract: The present invention includes a method for treating a patient in need of facilitated oxygen delivery through the lungs, additional lung surfactant, removal of material from inside the lung, or inflation of collapsed portions of the lung, comprising the step of introducing into the lung of the patient an effective therapeutic amount of a fluorocarbon liquid, the amount not exceeding the functional residual capacity of the lung of the patient upon exhalation taking into account any positive and expiratory pressure applied to the patient's lung. The method may also comprise the additional step of providing an oxygen-containing breathing gas to the patient while the fluorocarbon liquid is in the lung.
    Type: Application
    Filed: August 14, 2001
    Publication date: March 27, 2003
    Inventors: Nicholas Simon Faithfull, Jeffry Greg Weers
  • Publication number: 20020082485
    Abstract: Systems and methods are described for calculating, in real-time, various oxygenation parameters including total oxygen transport, mixed venous blood oxygen tension and mixed venous blood oxyhemoglobin saturation in a patient. The system preferably uses a computer, an arterial pressure line and a blood chemistry monitor to assist a physician in accurately determining when to give a patient a blood transfusion or otherwise alter the clinical management of that patient.
    Type: Application
    Filed: November 6, 2001
    Publication date: June 27, 2002
    Inventors: Nicholas Simon Faithfull, Glenn Rhoades
  • Patent number: 6390977
    Abstract: Systems are methods described for calculating, in real-time, various oxygenation parameters including total oxygen transport, mixed venous blood oxygen tension and mixed venous blood oxyhemoglobin saturation in a patient. The system preferably uses a computer, an arterial pressure line and a blood chemistry monitor to assist a physician in accurately determining when to give a patient a blood transfusion or otherwise alter the clinical management of that patient.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: May 21, 2002
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Glenn Rhoades
  • Patent number: RE38081
    Abstract: A method for hemodiluting a patient is disclosed which includes the steps of administering a biocompatible oxygen carrier in conjunction with surgery or organ ischemia or infarct while assessing the patient's PvO2 or other oxygenation indices, and administering to the patient additional oxygen carrier or autologous blood in response to the PvO2 value if necessary to maintain the PvO2 at or above the desired level.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: April 15, 2003
    Inventors: Nicholas Simon Faithfull, Peter E. Keipert, Duane J. Roth, Ronald M. Hopkins