Abstract: Provided are methods for determining the apolipoprotein E (ApoE) phenotype in a sample by mass spectrometry; wherein the ApoE allele(s) present in the sample is determined from the identity of the ions detected by mass spectrometry. In another aspect, provided herein are methods for diagnosis or prognosis of Alzheimer's disease or dementia.

Abstract: Methods are described for measuring the amount of C peptide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying C peptide in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.

Abstract: Provided are methods for detecting chromogranin A by mass spectrometry. In another aspect, provided herein are methods for quantitating chromogranin A by mass spectrometry. In another aspect, provided herein are methods for prognosis of or measuring the size of neuroendocrine tumors by mass spectrometry.

Abstract: The invention relates to the detection of non-metabolized vitamin D. In a particular aspect, the invention relates to methods for detecting underivatized non-metabolized vitamin D by mass spectrometry.

Abstract: Provided are methods for detecting chromogranin A by mass spectrometry. In another aspect, provided herein are methods for quantitating chromogranin A by mass spectrometry. In another aspect, provided herein are methods for prognosis of or measuring the size of neuroendocrine tumors by mass spectrometry.

Abstract: Various examples are provided related to methane detection in harsh environments. In one example, a method includes drawing a sample of air from at least one first location; delivering the sample to a volume within a sensor block at a second location, where the sensor block includes a gas concentration sensor in communication with the volume; and where a vacuum is applied to the volume within the sensor block to facilitate delivery of the sample to the second location. In another example, a system includes a sampling unit that houses a sensor block, where a sample tube is coupled to an inlet of the sensor block, which includes a gas concentration sensor; an ejector that facilitates delivery of a sample of air from the first location via the sample tube; and a control unit that can receive a gas concentration sensor output from the sampling unit for processing.

Abstract: Methods are described for determining the amount of insulin in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying insulin in a biological sample utilizing purification methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.

Abstract: The present disclosure relates to methods of detecting various analytes, including glycated hemoglobin (HbA1c) and total hemoglobin (THb), in a biological sample obtained with a microsampling device.

Abstract: The present invention includes a system for use in a vehicle for determining the terrain type in proximity to a vehicle. The system comprises a processor configured to receive primary output data from at least one vehicle-mounted sensor, and secondary output data from a secondary data source; and a data memory configured to store pre-determined primary data relating primary output data for the at least one vehicle-mounted sensor to a particular terrain type, and store at least one data set relating to one or more terrain types. The processor is configured to compare the primary output data with the pre-determined data to determine an indication of the particular terrain type corresponding to the primary output data, and compare the secondary output data with a data set corresponding to the indication of the particular terrain type.

Abstract: In one embodiment, a method includes generating, at a multi-view display, a first content to be viewed at a first angle and a second content to be viewed at a second angle. The first content and the second content are displayed simultaneously. The method also includes receiving, at a touch-screen panel coupled to the multi-view display, a first plurality of capacitive signals. The method then generates, by the touch-screen panel, a first touch-screen panel heatmap based on the received first plurality of capacitive signals. The method afterwards determines, based on the first touch-screen panel heatmap, whether a first user input is received with respect to the first content or the second content. The method then assigns, based on determining the first user input corresponds to either the first content or the second content, the first user input to the first content or the second content.

Abstract: The invention relates to the quantitative measurement of steroidal compounds by mass spectrometry. In a particular aspect, the invention relates to methods for quantitative measurement of steroidal compounds from multiple samples by mass spectrometry.

Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.

Abstract: In one embodiment, a method includes generating, at a multi-view display, a first content to be viewed at a first angle and a second content to be viewed at a second angle. The first content and the second content are displayed simultaneously. The method also includes receiving, at a touch-screen panel coupled to the multi-view display, a first plurality of capacitive signals. The method then generates, by the touch-screen panel, a first touch-screen panel heatmap based on the received first plurality of capacitive signals. The method afterwards determines, based on the first touch-screen panel heatmap, whether a first user input is received with respect to the first content or the second content. The method then assigns, based on determining the first user input corresponds to either the first content or the second content, the first user input to the first content or the second content.

Abstract: Various examples are provided related to linear resonant machines. In one example, a linear resonant machine includes an electrical stator including a winding; a translator disposed within the winding; and one or more springs that can provide axial coupling force. The one or more springs can include a flexure plate coupled between the translator and a chassis or the stator assembly of the linear resonant machine. The flexure plates can oscillate the translator axially at a resonant frequency within the at least one winding of the electrical stator. One or more engines can be coupled to a shaft of the translator to operate the linear resonant machine as a generator. The winding of the electrical stator can be excited to operate the linear resonant machine as a motor.

Abstract: A system and method for a hybrid multimode input device includes a multimode input device capable of a two-dimensional (2D) mode of operation and a three-dimensional (3D) mode of operation. The device includes a two-dimensional (2D) position sensor, a three-dimensional (3D) position sensor, and a processor. The processor is configured to enter a 3D input mode when the processor detects that the input device is in a first orientation, and enter a 2D input mode when the processor detects that the input device is in a second orientation. The 2D input mode is configured to provide 2D position data to a connected computer system, and wherein the 3D input mode is configured to provide 3D position data to the connected computer system.

Abstract: Methods are provided for detecting the amount of one or more HRT panel analytes (i.e., estrone (E1), estrone sulfate (E1s), 17?-estradiol (E2a), 17?-estradiol (E2b), estradiol sulfate (E2s), estriol (E3), equilin (EQ), 17?-dihydroequilin (EQa), 17?-dihydroequilin (EQb), Equilenin (EN), 17?-dihydroequilenin (ENa), 17?-dihydroequilenin (ENb), and ?8,9-dehydroestrone (dE1)) in a sample by mass spectrometry. The methods generally involve ionizing one or more HRT panel analytes in a sample and quantifying the generated ions to determine the amount of one or more HRT panel analytes in the sample. In methods where amounts of multiple HRT panel analytes are detected, the amounts of multiple analytes are detected in the same sample injection.

Abstract: Provided are methods for determining the amount of tamoxifen and its metabolites in a sample by mass spectrometry. In some aspects, the methods provided herein determine the amount of norendoxifen. In some aspects, the methods provided herein determine the amount of norendoxifen and tamoxifen. In some aspects, the methods provided herein determine the amount of norendoxifen and other tamoxifen metabolites. In some aspects, the methods provided herein determine the amount of tamoxifen, norendoxifen, and other tamoxifen metabolites.

Abstract: Methods are described for measuring the amount of C peptide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying C peptide in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.

Abstract: The invention relates to the detection of non-metabolized vitamin D. In a particular aspect, the invention relates to methods for detecting underivatized non-metabolized vitamin D by mass spectrometry.

Abstract: A system and method for a hybrid multimode input device includes a multimode input device capable of a two-dimensional (2D) mode of operation and a three-dimensional (3D) mode of operation. The device includes a two-dimensional (2D) position sensor, a three-dimensional (3D) position sensor, and a processor. The processor is configured to enter a 3D input mode when the processor detects that the input device is in a first orientation, and enter a 2D input mode when the processor detects that the input device is in a second orientation. The 2D input mode is configured to provide 2D position data to a connected computer system, and wherein the 3D input mode is configured to provide 3D position data to the connected computer system.