Abstract: Novel exendin peptide compounds are provided.

Abstract: A reciprocating saw is provided which includes a drive shaft having a saw blade clamping means at an end thereof for securing a saw blade thereto in use, and drive means for driving reciprocation of the drive shaft and thus an attached saw blade relative to a body portion of the saw in use. The saw further includes saw blade support means for engaging a surface of the saw blade in use for supporting the same. The saw blade support means is pivotally mounted to a part of the body portion of the saw or to a substantially stationary bearing associated with the drive shaft to allow passive movement of the blade support means with the drive shaft and/or saw blade in use.

Abstract: Provided are methods for lowering plasma lipid in an individual in need of or desirous of lowering plasma lipid by administering an amount of an exendin or an exendin agonist analog effective to lower plasma lipid.

Abstract: Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that affect satiety. The methods are useful for treating conditions or disorders, including obesity, Type II diabetes, eating disorders, and insulin-resistance syndrome. The methods are also useful for lowering the plasma glucose level, lowering the plasma lipid level, reducing the cardiac risk, reducing the appetite, and reducing the weight of subjects. Pharmaceutical compositions for use in the methods of the invention are also disclosed.

Abstract: The present invention relates to methods of treating polycystic ovary syndrome (PCOS) comprising administering glucagon-like peptide-1 (GLP-1), exendin, and analogs and agonists thereof, to subjects suffering therefrom.

Abstract: A power tool is provided including a housing and drive means for driving a component to perform an operation on a workpiece. A base plate is provided on a base of said housing and said base plate is brought into contact with the workpiece when performing the operation. The tool further includes storage means adapted to store at least one component when not in use. The storage means are formed at least partially in or on the base plate.

Abstract: Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that affect satiety. The methods are useful for treating conditions or disorders, including obesity, Type II diabetes, eating disorders, and insulin-resistance syndrome. The methods are also useful for lowering the plasma glucose level, lowering the plasma lipid level, reducing the cardiac risk, reducing the appetite, and reducing the weight of subjects. Pharmaceutical compositions for use in the methods of the invention are also disclosed.

Abstract: The invention relates to apparatus for use in the sharpening of tools and in particular to apparatus for the sharpening of selected ones of a plurality of different tools, said apparatus including a grinding wheel and a plurality of tool holders. At least one of the tool holders is connected to the apparatus so as to be movable between out-of-use and in-use positions thereby allowing the cool holder to be positioned accurately. In one embodiment the housing is provided on a base which is provided with storage means for other sharpening implements and/or accessories.

Abstract: The invention relates to a blade which allows a saw blade, such as a blade for a reciprocating saw in the form of a jigsaw, to be held securely therein for use and to allow the same to be selectively inserted and removed without the need for tools to be used by the user. The insertion of the blade into the holder can be achieved by the user moving the end of the blade into a channel in the blade holder whereupon clamping automatically occurs and the release of the blade requires the manipulation of a release means by the user so that the blade cannot be inadvertently released from the blade holder. The holder incorporates a roller which is movable within a chamber within the blade holder between release and clamping positions.

Abstract: Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that affect satiety. The methods are useful for treating conditions or disorders, including obesity, Type II diabetes, eating disorders, and insulin-resistance syndrome. The methods are also useful for lowering the plasma glucose level, lowering the plasma lipid level, reducing the cardiac risk, reducing the appetite, and reducing the weight of subjects. Pharmaceutical compositions for use in the methods of the invention are also disclosed.

Abstract: Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that affect satiety. The methods are useful for treating conditions or disorders, including obesity, Type II diabetes, eating disorders, and insulin-resistance syndrome. The methods are also useful for lowering the plasma glucose level, lowering the plasma lipid level, reducing the cardiac risk, reducing the appetite, and reducing the weight of subjects. Pharmaceutical compositions for use in the methods of the invention are also disclosed.

Abstract: An optical network comprises a bidirectional link connecting two nodes (1) through two optical fibers (3). Optical output signals from optical transmitters (7) in a node are provided to transponders (11) issuing optical signals of well-defined wavelengths to a power combiner (13), from which optical signals are forwarded to the other node on the respective fiber. The network can have protection for failures of various components. Thus, a spare transponder (21) can receive the optical output signals of an optical transmitter (7) in the case of a failure of an ordinary transponder (11). The spare transponder (21) is also connected to the combiner (13). The optical transmitters (7) and receivers (9) can be duplicated by providing spare transmitters (7?) and spare receivers (9?). Various arrangements can be used for connecting the output of a transmitter to an ordinary transponder or the spare transponder.

Abstract: Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that affect satiety. The methods are useful for treating conditions or disorders, including obesity, Type II diabetes, eating disorders, and insulin-resistance syndrome. The methods are also useful for lowering the plasma glucose level, lowering the plasma lipid level, reducing the cardiac risk, reducing the appetite, and reducing the weight of subjects. Pharmaceutical compositions for use in the methods of the invention are also disclosed.

Abstract: The present invention provides a system and method for managing distribution of content to a device, the system comprising a database for storing a number of elements as a hierarchical structure, content identifiers being able to be associated with elements in the hierarchical structure, and one of the elements representing the device, and a server for referencing the hierarchical structure in the database to generate a profile for the device, the profile containing a number of content identifiers indicating content to be provided to the device. A device manager is associated with the device and arranged to receive the profile from the server and to use the content identifiers in the profile to cause the content indicated by the profile to be provided to the device, a record being kept identifying the content provided to the device in accordance with the profile.

Abstract: A monitor includes cardiac and movement sensors 36, 34 responsive to a user's heart beat and a user's movement. The monitor includes a processor coupled to the sensors for generating heart-rate or other cardiac data and user movement or activity data. These data can be stored in a memory and used to analyse the relationship between heart rate and physical exertion.

Abstract: Methods for reducing gastric motility and delaying gastric emptying for therapeutic and diagnostic purposes are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist. Methods for treating conditions associated with elevated, inappropriate, or undesired post-prandial blood glucose levels are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist alone or in conjunction with other anti-gastric emptying agents.

Abstract: The present invention relates to methods of treating polycystic ovary syndrome (PCOS) comprising administering glucagon-like peptide-1 (GLP-1), exendin, and analogs and agonists thereof, to subjects suffering therefrom.

Abstract: Process for the preparation of foamed thermoplastic polyurethanes characterized in that the foaming of the thermoplastic polyurethane is carried out in the presence of thermally expandable microspheres and a flow aid.

Abstract: A system and method for controlling the output power of an optical amplifier in a node in a network, wherein the output power of the amplifier is controlled via a pump laser in a control circuit. The node reads a supervisory channel comprising information on how to control the amplifier. The node then uses the information for the control of the amplifier.

Abstract: Compositions and methods using antiparallel heterogeneous &agr;-helical coiled-coil (AHEC) regions for the linkage and stabilization of antibody Fv domains are provided.