Abstract: A laser structure including a Si or Ge substrate, a III-V buffer layer formed on the substrate, a light emitting diode (LED) formed on the buffer layer configured to produce visible light, a lens disposed on the LED to focus light from the LED, a photonic crystal layer formed on the LED to receive the light focused by the lens, and a monolayer semiconductor nanocavity laser formed on the photonic crystal layer for receiving light through the photonic crystal layer from the LED. The LED and the laser are formed monolithically and the LED acts as an optical pump for the laser.

Abstract: A manufacturing method for a test structure includes: providing a substrate, and forming a gate dielectric film and a conductive film being stacked successively on the substrate; patterned etching at least the conductive film to form a plurality of gate structures discretely located on the substrate, the distance between adjacent gate structures in an arrangement direction of the gate structure being less than or equal to 110 nm; forming isolation sidewalls on two opposite sides of the gate structures; and, implanting doping ions into the substrate to form doped regions by taking the gate structures and the isolation sidewalls as masks, the distance between the doping depth of the doped regions and the top surface of the substrate in a direction perpendicular to the surface of the substrate being less than 10 nm.

Abstract: The present disclosure provides a semiconductor structure and a manufacturing method thereof. The manufacturing method of a semiconductor structure includes: providing an initial semiconductor structure, where the initial semiconductor structure includes a substrate and a polycrystalline silicon layer; forming a first mask layer on the initial semiconductor structure, where the first mask layer has a first ion implantation window, and the first ion implantation window defines a position of a gate electrode of a first transistor; and performing a first ion implantation process to perform work function adjustment on the gate electrode of the first transistor through the first ion implantation window, to form a semiconductor structure.

Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.

Abstract: Methods of depositing an encapsulation stack without damaging underlying layers are discussed. The encapsulation stacks are highly conformal, have low etch rates, low atomic oxygen concentrations, good hermeticity and good adhesion. These films may be used to protect chalcogen materials in PCRAM devices. Some embodiments utilize a two-step process comprising a first ALD process to form a protective layer and a second plasma ALD process to form an encapsulation layer.

Abstract: Systems and methods comprising a metering device located on an electricity distribution grid, the metering device comprising one or more processors and memory. The metering device can detect a drop in characteristic of electricity below a threshold indicating a fault on the electricity distribution grid. The metering device can generate, responsive to the drop in the characteristic of electricity below the threshold, a time series of a rate of change of the characteristic of electricity for a predetermined number of cycles subsequent to the detection of the drop. The metering device can determine, based on a comparison of the time series of the rate of change with a predetermined pattern, a location of the metering device on the electricity distribution grid relative to a location of the fault on the electricity distribution grid.

Abstract: Genetically programmed microorganisms, such as bacteria or virus, pharmaceutical compositions thereof, and methods of modulating and treating cancers are disclosed.

Abstract: Systems and techniques that facilitate quantum tuning via permanent magnetic flux elements are provided. In various embodiments, a system can comprise a qubit device. In various aspects, the system can further comprise a permanent magnet having a first magnetic flux, wherein an operational frequency of the qubit device is based on the first magnetic flux. In various instances, the system can further comprise an electromagnet having a second magnetic flux that tunes the first magnetic flux. In various cases, the permanent magnet can comprise a nanoparticle magnet. In various embodiments, the nanoparticle magnet can comprise manganese nanoparticles embedded in a silicon matrix. In various aspects, the system can further comprise an electrode that applies an electric current to the nanoparticle magnet in a presence of the second magnetic flux, thereby changing a strength of the first magnetic flux.

Abstract: A method of producing a quantum circuit includes forming a mask on a substrate to cover a first portion of the substrate, implanting a second portion of the substrate with ions, and removing the mask, thereby providing a nanowire. The method further includes forming a first lead and a second lead, the first lead and the second lead each partially overlapping the nanowire. In operation, a portion of the nanowire between the first and second leads forms a quantum dot, thereby providing a quantum dot Josephson junction. The method further includes forming a third lead and a fourth lead, one of the third and fourth leads partially overlapping the nanowire, wherein the third lead is separated from the fourth lead by a dielectric layer, thereby providing a Dolan bridge Josephson junction. The nanowire is configured to connect the quantum dot Josephson junction and the Dolan bridge Josephson junction in series.

Abstract: The present invention generally pertains to methods of preventing disulfide scrambling in non-reducing liquid chromatography-mass spectrometry analysis of a protein of interest. In particular, the present invention pertains to the addition of maleimide to a non-reducing liquid chromatography-mass spectrometry analysis of a protein to prevent disulfide scrambling.

Abstract: The present invention provides methods and systems to identify host cell protein (HCP) impurities in a sample containing high-abundance proteins. The HCP impurities can be enriched using interacting peptide ligands which have been attached to solid support. The HCP impurities can be eluted from the solid support. The isolated HCP impurities can be subjected to limited digestion to generate components of the isolated HCP impurities which can subsequently be identified using a mass spectrometer. The present invention also provides methods and systems to identify sequence variant (SV) peptides or proteins in a sample containing high-abundance proteins. The SV peptides or proteins can be enriched using interacting peptide ligands which have been attached to solid support. The SV peptides or proteins can be eluted from the solid support.

Abstract: A phase change (PCM) memory device that includes a PCM and a resistance-capacitance (RC) circuit. The PCM has one or more PCM properties, each PCM property has a plurality of PCM property states. As the PCM property states of a given property are Set or Reset, the PCM property states each produce an incremental change to a property level of the respective/associated PCM property, e.g., PCM conductance. The incremental changes to property level of the PCM memory device are in response to application of one or more of a pulse number of voltage pulses. The RC circuit produces a configuring current that flows through the PCM in response to one or more of the voltage pulses. The configuring current modifies one or more of the incremental changes to one or more of the property levels so that the property level changes lineally with respect to the pulse number. The PCM memory device has use in a synapse connector, e.g., in a memory array.

Abstract: Methods for plasma enhanced atomic layer deposition (PEALD) of low-? films are described. A method of depositing a film comprises exposing a substrate to a silicon precursor having the general formula (I) wherein R1, R2, R3, R4, R5, and R6 are independently selected from hydrogen (H), substituted alkyl, or unsubstituted alkyl; purging the processing chamber of the silicon precursor; exposing the substrate to a carbon monoxide (CO) plasma to form one or more of a silicon oxycarbide (SiOC) or silicon oxycarbonitride (SiOCN) film on the substrate; and purging the processing chamber.

Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins.

Abstract: Systems and methods are directed controlling components of a utility grid. The system can receive signals. The system can determine one or more statistical metrics based on the signals. The system can generate an input matrix. The system can input the input matrix into a machine learning model. The system can predict, based on the input matrix and via the machine learning model, the value for the signal of the utility grid at a time period for which the value is not provided in the input matrix. The system can provide a command to control a component of the utility grid responsive to the value for the signal of the utility grid predicted by the machine learning model.

Abstract: Genetically programmed microorganisms, such as bacteria or virus, pharmaceutical compositions thereof, and methods of modulating and treating cancers are disclosed.

Abstract: A plurality of music samples and a plurality of images corresponding to the music samples may be stored in a database. The plurality of music samples may be sorted in an order of priority. Information associated with the plurality music samples may be sent to a user device. The user device may display the plurality of images corresponding to the plurality of music samples in the order of priority. The user device may receive information indicative of at least one video associated with a music sample in response to receiving user input indicative of a selection of an image among the plurality of images. The user device may display at least one sample video image corresponding to the at least one video associated with the music sample.

Abstract: A modified cytidine compound, that is, an aminooxy group is modified at the 4-position of a cytidine pyrimidine ring to produce derivative cytidine and nucleic acid containing the derivative cytidine, such as RNA. The expression level of the nucleic acid containing the modified cytidine, in particular mRNA, in the body is significantly improved.

Abstract: A method for 3D gesture interaction across electronic devices includes: measuring spatial location information of the electronic devices based on Location Technology; generating a 3D gesture field of the electronic devices based on the spatial location information; setting the location update method, the detection method of 3D gesture, the frequency band of detecting 3D gesture, and the time sequence of detecting gesture at different devices; detecting the cooperative gesture; generating interactive auxiliary messages based on the detection of the cooperative gesture; updating the 3D gesture field if the location of any devices have update; identifying the cooperative gesture in the 3D gesture field of the electronic devices; performing the commands corresponding to the cooperative gesture; detecting that the cooperative gesture is beyond the 3D gesture field of the electronic devices; and sending the cooperative gesture to other electronic devices based on the direction of the cooperative gesture.

Abstract: Disclosed is a method for detecting Ophiocephalus argus cantor under intra-class occulusion based on cross-scale layered feature fusion, including image collecting, image processing and network model, where collected images are labeled, image sizes are adjusted to obtain input images, and the input images are input into an object detection network, integrated by convolution and inserted into cross-scale layered feature fusion modules, characterized by including dividing all features input into the cross-scale layered feature fusion modules into n layers, composed of s feature mapping subsets, and fusing features of each feature mapping subset with that of other feature mapping subsets, and connecting; carrying out convolution operation, outputting training result; adjusting network parameters by a loss function to obtain parameters for a network model; inputting final output candidate boxes into a non-maximum suppression module to screen correct prediction boxes, so that prediction result is obtained.