Patents by Inventor Nobuhiko Ogura
Nobuhiko Ogura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9310492Abstract: A radiographic image reading device includes a reading unit configured to photoelectrically read photostimulated luminescence light produced from a storage phosphor sheet illuminated with excitation light, the storage phosphor sheet, at which a radiographic image is stored, being scanned by a scanning unit using the excitation light; and a control unit configured to control the reading unit so as to cause the reading unit, in a case of reading at a first resolution, to read with excitation light at a first scanning speed and a first intensity and, in a case of reading at a second resolution that is a higher resolution than the first resolution, to read with excitation light at a second scanning speed that is slower than the first scanning speed and a second intensity that is smaller than the first intensity.Type: GrantFiled: July 25, 2014Date of Patent: April 12, 2016Assignee: FUJIFILM CorporationInventors: Hiromi Ishikawa, Yasunori Ohta, Tomoki Inoue, Nobuhiko Ogura
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Publication number: 20150090910Abstract: A radiographic image reading device includes a reading unit configured to photoelectrically read photostimulated luminescence light produced from a storage phosphor sheet illuminated with excitation light, the storage phosphor sheet, at which a radiographic image is stored, being scanned by a scanning unit using the excitation light; and a control unit configured to control the reading unit so as to cause the reading unit, in a case of reading at a first resolution, to read with excitation light at a first scanning speed and a first intensity and, in a case of reading at a second resolution that is a higher resolution than the first resolution, to read with excitation light at a second scanning speed that is slower than the first scanning speed and a second intensity that is smaller than the first intensity.Type: ApplicationFiled: July 25, 2014Publication date: April 2, 2015Inventors: Hiromi ISHIKAWA, Yasunori OHTA, Tomoki INOUE, Nobuhiko OGURA
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Publication number: 20140183368Abstract: A radiographic image reading device includes: a casing that has a conveyance inlet/outlet for conveying in and conveying out a storage phosphor sheet on which a radiographic image is recorded, and a discharge outlet for discharging the storage phosphor sheet; an image reading unit that reads the radiographic image recorded on a storage phosphor sheet that has been conveyed in from the conveyance inlet/outlet; and a conveyance unit that conveys the storage phosphor sheet that has been conveyed in from the conveyance inlet/outlet to a read position at which reading is performed by the image reading unit and that conveys the storage phosphor sheet, from which the radiographic image has been read, to the conveyance inlet/outlet or the discharge outlet.Type: ApplicationFiled: November 11, 2013Publication date: July 3, 2014Applicant: FUJIFILM CORPORATIONInventors: Hiromi ISHIKAWA, Nobuhiko OGURA, Yasunori OHTA
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Publication number: 20130320238Abstract: A phosphor sheet includes a flexible substrate; a phosphor layer formed on a front face of the substrate, and plural magnets provided on a back face of the substrate.Type: ApplicationFiled: May 29, 2013Publication date: December 5, 2013Inventor: Nobuhiko OGURA
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Publication number: 20130303389Abstract: The present invention provides a method of confirming the gene expression, useful in the decision of a five year survival rate of a patient with lung cancer and the use of a DNA probe kit in the method. A method useful in the decision of a survival rate of a patient with non-small cell lung cancer comprising confirming the expression strength of at least one gene in lung cancer tissues isolated from the patient.Type: ApplicationFiled: July 16, 2012Publication date: November 14, 2013Applicants: FUJIFILM Corporation, Aichi PrefectureInventors: TAKASHI TAKAHASHI, Shuta Tomita, Tetsuya Mitsudomi, Yasushi Yatabe, Nobuhiko Ogura, Masato Some
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Patent number: 8244478Abstract: The present invention provides a method of confirming the gene expression, useful in the decision of a five year survival rate of a patient with lung cancer and the use of a DNA probe kit in the method. A method useful in the decision of a survival rate of a patient with non-small cell lung cancer comprising confirming the expression strength of at least one gene in lung cancer tissues isolated from the patient.Type: GrantFiled: November 9, 2010Date of Patent: August 14, 2012Assignees: Aichi Prefecture, FUJIFILM CorporationInventors: Takashi Takahashi, Shuta Tomita, Tetsuya Mitsudomi, Yasushi Yatabe, Nobuhiko Ogura, Masato Some
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Publication number: 20110081652Abstract: The present invention provides a method of confirming the gene expression, useful in the decision of a five year survival rate of a patient with lung cancer and the use of a DNA probe kit in the method. A method useful in the decision of a survival rate of a patient with non-small cell lung cancer comprising confirming the expression strength of at least one gene in lung cancer tissues isolated from the patient.Type: ApplicationFiled: November 9, 2010Publication date: April 7, 2011Applicants: Aichi Preferecture, FUJIFILM CorporationInventors: Takashi TAKAHASHI, Shuta Tomita, Tetsuya Mitsudomi, Yasushi Yatabe, Nobuhiko Ogura, Masato Some
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Patent number: 7856318Abstract: The present invention provides a method of confirming the gene expression, useful in the decision of a five year survival rate of a patient with lung cancer and the use of a DNA probe kit in the method. A method useful in the decision of a survival rate of a patient with non-small cell lung cancer comprising confirming the expression strength of at least one gene selected from the group consisting of in lung cancer tissues isolated from the patient.Type: GrantFiled: December 10, 2004Date of Patent: December 21, 2010Assignees: Aichi Prefecture, FUJIFILM CorporationInventors: Takashi Takahashi, Shuta Tomita, Tetsuya Mitsudomi, Yasushi Yatabe, Nobuhiko Ogura, Masato Some
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Patent number: 7715012Abstract: A sensor unit of a surface plasmon resonance (SPR) assay system includes a transparent dielectric medium. A thin film has a first surface and a sensing surface. The first surface is connected with the dielectric medium to constitute an interface. The sensing surface is back to the first surface, for detecting (bio) chemical reaction. A flow cell block has a flow channel for flowing of the sample to the sensing surface. Attenuated total reflection of illuminating light is checked at the interface, to analyze interaction between ligand and analyte as samples. The flow channel includes a first inner surface, disposed opposite to the sensing surface to extend along, for passing the sample to flow between. The first inner surface has a height, defined with reference to the sensing surface, and in a range of 200-500 microns.Type: GrantFiled: February 27, 2009Date of Patent: May 11, 2010Assignee: FUJIFILM CorporationInventors: Nobuhiko Ogura, Hitoshi Shimizu, Koji Kuruma, Hisashi Ohtsuka, Tatsuo Fujikura, Shu Sato
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Publication number: 20100027005Abstract: A biosensor detection apparatus having increased processing power for measurement without complicated structure and increased size. The apparatus includes one or more spectrometers configured to spectrally separate each light beam reflected from each of a plurality of measurement regions defined on a biosensor simultaneously, and one or more optical receivers configured to receive each light beam spectrally separated by the one or more spectrometers simultaneously and to obtain a spectral intensity distribution of each light beam separately.Type: ApplicationFiled: September 21, 2007Publication date: February 4, 2010Inventor: Nobuhiko Ogura
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Publication number: 20090306903Abstract: A screening apparatus divides measurement data representing the amount of binding between one kind of protein and each of a plurality of kinds of compounds, obtained by a measurement apparatus, into groups, each including data obtained in a same measurement condition. The screening apparatus obtains a representative value of measurement data that is obtained when the protein and a compound are not bound to each other for each of the groups by using the measurement data belonging to the respective groups, and sets a threshold value for extracting a hit compound for each of the groups by using corrected measurement data, obtained by correcting the measurement data for each of the groups so that the representative value obtained for each of the groups becomes the same value. Then, a hit compound is extracted by comparing the threshold value with the corrected measurement data.Type: ApplicationFiled: January 16, 2007Publication date: December 10, 2009Applicant: FUJI FILM CORPORATIONInventor: Nobuhiko Ogura
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Patent number: 7625748Abstract: A flow cell device is incorporated in the sensor unit for surface plasmon resonance (SPR) assay. A box shaped flow cell body has a lower surface, and is disposed in contact of the lower surface with a sensing surface for detecting reaction of sample. Two flow channels are formed in the flow cell body, for flow of the sample. Each of the flow channels include a fluid passageway, formed in the lower surface, for flow of the sample in contact with the sensing surface. Two end cavities are formed in an upper surface of the flow cell body and open therein, to extend from ends of the fluid passageway. The flow channels are arranged adjacent to one another, disposed to extend in a direction of the flow. Fluid passageways of the flow channels are overlapped partially on one another in a flow cell longitudinal direction of the flow cell body.Type: GrantFiled: June 27, 2006Date of Patent: December 1, 2009Assignee: FUJIFILM CorporationInventors: Nobuhiko Ogura, Hitoshi Shimizu, Tatsuo Fujikura, Koji Kuruma
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Publication number: 20090195784Abstract: A sensor unit of a surface plasmon resonance (SPR) assay system includes a transparent dielectric medium. A thin film has a first surface and a sensing surface. The first surface is connected with the dielectric medium to constitute an interface. The sensing surface is back to the first surface, for detecting (bio) chemical reaction. A flow cell block has a flow channel for flowing of the sample to the sensing surface. Attenuated total reflection of illuminating light is checked at the interface, to analyze interaction between ligand and analyte as samples. The flow channel includes a first inner surface, disposed opposite to the sensing surface to extend along, for passing the sample to flow between. The first inner surface has a height, defined with reference to the sensing surface, and in a range of 200-500 microns.Type: ApplicationFiled: February 27, 2009Publication date: August 6, 2009Applicant: FUJIFILM CorporationInventors: Nobuhiko Ogura, Hitoshi Shimizu, Koji Kuruma, Hisashi Ohtsuka, Tatsuo Fujikura, Shu Sato
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Patent number: 7515270Abstract: A sensor unit of a surface plasmon resonance (SPR) assay system includes a transparent dielectric medium. A thin film has a first surface and a sensing surface. The first surface is connected with the dielectric medium to constitute an interface. The sensing surface is back to the first surface, for detecting (bio)chemical reaction. A flow cell block has a flow channel for flowing of the sample to the sensing surface. Attenuated total reflection of illuminating light is checked at the interface, to analyze interaction between ligand and analyte as samples. The flow channel includes a first inner surface, disposed opposite to the sensing surface to extend along, for passing the sample to flow between. The first inner surface has a height, defined with reference to the sensing surface, and in a range of 200-500 microns.Type: GrantFiled: March 6, 2006Date of Patent: April 7, 2009Assignee: FUJIFILM CorporationInventors: Nobuhiko Ogura, Hitoshi Shimizu, Koji Kuruma, Hisashi Ohtsuka, Tatsuo Fujikura, Shu Sato
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Patent number: 7473547Abstract: A test piece for use in biological analysis of a sample is formed of a strip-like substrate and numbers of known specific binding agents which are different from each other and are arranged in a line at predetermined intervals in the longitudinal direction of the strip-like substrate.Type: GrantFiled: August 13, 1999Date of Patent: January 6, 2009Assignee: FUJIFILM CorporationInventor: Nobuhiko Ogura
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Patent number: 7470549Abstract: It is an object of the present invention to provide a method for simultaneously carrying out the detection or measurement of a substance interacting with a physiologically active substance immobilized on a biosensor and the analysis of the effects of the above substance on the biological activity of the physiologically active substance. The present invention provides a method using a biosensor formed by immobilizing a physiologically active substance on a substrate, wherein the detection and measurement of a substance interacting with said physiologically active substance and the measurement of the biological activity of said physiologically active substance are carried out on said single biosensor.Type: GrantFiled: May 26, 2005Date of Patent: December 30, 2008Assignee: FUJIFILM CorporationInventors: Masayoshi Yamamoto, Toshihide Ezoe, Nobuhiko Ogura, Katsumi Hayashi
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Patent number: 7465588Abstract: An assay apparatus is loaded with a sensor unit as surface plasmon resonance (SPR) biosensor, which includes a transparent dielectric medium and thin film. A first surface of the thin film is a thin film/dielectric interface. Its sensing surface causes reaction of sample fluid. An optical assay unit assays reaction of the sample fluid by detecting illuminating light reflected by the interface. Measured data from the optical assay unit is compared with a reference parameter, to evaluate suitability of the measured data for analysis. If lack of the suitability is estimated in the evaluation, a succeeding density of the sample fluid to be used in a succeeding evaluating assay is determined according to the measured data with the estimated lack of the suitability. The sample fluid is prepared at the succeeding density by mixing with diluent fluid, and then is used for the succeeding evaluating assay.Type: GrantFiled: September 30, 2005Date of Patent: December 16, 2008Assignee: FUJIFILM CorporationInventors: Katsuaki Muraishi, Nobuhiko Ogura
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Patent number: 7453573Abstract: A measuring apparatus and a measuring method are configured to measure a concentration of an organic solvent in a sample solution, measure a concentration of the organic solvent in a concentration control solution, calculate a mixture amount by which the concentration control solution is mixed into the sample solution of a preset amount so that the concentration of the organic solvent in the sample solution is equal to a preset concentration based on the two concentrations, mix the concentration control solution of the calculated mixture amount with the sample solution of the preset amount, supply a mixture solution obtained by the mixing unit to a measurement region in which a bioactive substance is immobilized in advance, and measure an interaction between the bioactive substance and the sample substance in the mixture solution based on a result of measuring a refraction index of a light incident on the measurement region.Type: GrantFiled: September 27, 2007Date of Patent: November 18, 2008Assignee: FUJIFILM CorporationInventor: Nobuhiko Ogura
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Patent number: 7439078Abstract: An object of the present invention is to provide a method for measuring the dissociation rate coefficient (Kd) by surface plasmon resonance analysis without measuring the theoretical maximum amount of binding (Rmax). The present invention provides a method for measuring the dissociation rate coefficient (Kd) of the reaction between an analyte molecule immobilized on a metal surface and a molecule that interacts with the analyte molecule by assaying changes in surface plasmon resonance signals using a surface plasmon resonance measurement device, wherein the signal and the slope of the dissociation curve of the surface plasmon resonance signal curves, or the signal ratio are used to calculate the dissociation rate coefficient (Kd).Type: GrantFiled: August 16, 2005Date of Patent: October 21, 2008Assignee: FUJIFILM CorporationInventors: Hisashi Ohtsuka, Nobuhiko Ogura
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Publication number: 20080079944Abstract: A measuring apparatus and a measuring method are configured to measure a concentration of an organic solvent in a sample solution, measure a concentration of the organic solvent in a concentration control solution, calculate a mixture amount by which the concentration control solution is mixed into the sample solution of a preset amount so that the concentration of the organic solvent in the sample solution is equal to a preset concentration based on the two concentrations, mix the concentration control solution of the calculated mixture amount with the sample solution of the preset amount, supply a mixture solution obtained by the mixing unit to a measurement region in which a bioactive substance is immobilized in advance, and measure an interaction between the bioactive substance and the sample substance in the mixture solution based on a result of measuring a refraction index of a light incident on the measurement region.Type: ApplicationFiled: September 27, 2007Publication date: April 3, 2008Applicant: FUJIFILM CORPORATIONInventor: Nobuhiko Ogura