Abstract: It is intended to easily dispense a minute amount of nonvolatile liquid. In a preferred embodiment, in dispensing of mineral oil (nonvolatile liquid), dispensing is conducted in the condition that the amount of air contained in a tip (70) is small by aspirating a larger amount of mineral oil (40) than a single dispensing amount in the tip (70) of a nozzle (28).

Abstract: Disclosed is a reaction kit for preventing the entry of foreign matter into a reaction plate from the outside and the pollution of a surrounding environment. The reaction kit includes: a reaction plate (2) having, on the top surface side thereof, a reaction container (4) for carrying out the reaction of a sample and a reagent container (12) containing a reagent used for the reaction of a sample and sealed with a film (14); a dispensation tip (20) arranged on the top surface side of the reaction plate (2); a cover (24) covering a space above the top surface of the reaction plate (2) and movably supporting the dispensation tip (20) so that a distal end thereof is located inside the space covered with the cover (4) and a proximal end thereof is located outside the space; and a sample container (32) for introducing a sample into the space covered with the cover (24) from the outside through a sealable opening (31) provided in a part of the cover (24).

Abstract: The processing apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips so that the multiple main flow paths are provided; a pretreatment part common to the multiple main flow paths for performing a pretreatment step prior to an analysis step in each of the multiple main flow paths; a processing part for performing analysis in each of the main flow paths independently of the others; and a control part controlling an operation in the pretreatment part so that when a pretreatment step for one main flow path ends, a pretreatment for a next main flow path starts and further controlling an operation in the processing part so that an analysis is subsequently performed for the main flow path where the pretreatment step has ended.

Abstract: Intrusion of foreign matters from the outside of a reaction container plate and environmental contamination onto the outside are prevented. The reaction container plate (1) comprises a container base (3) having a reaction container (5), a channel base (11) having an introduction hole (11b) above the reaction container (5) and arranged on the surface of the container base (3), and a channel cover (13) arranged on the channel base (11) in order to form in cooperation with the surface of the channel base, an introduction channel (15) passing above the introduction hole (11b). The channel (13) is formed to be enclosed. The introduction hole (11b) does not allow liquid to pass under an introduction pressure state in the channel (15) where the liquid is introduced into the channel (15) but allows the liquid in the channel (15) to pass to the reaction container (5) side under a pressurized state where the inside of the channel (15) is pressurized higher than the introduction pressure.

Abstract: The analysis apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips so that the multiple main flow paths are provided; a pretreatment part common to the multiple main flow paths for performing a pretreatment step prior to an analysis step in each of the multiple main flow paths; a processing part for performing analysis in each of the main flow paths independently of the others; and a control part controlling an operation in the pretreatment part so that when a pretreatment step for one main flow path ends, a pretreatment for a next main flow path starts and further controlling an operation in the processing part so that an analysis is subsequently performed for the main flow path where the pretreatment step has ended.

Abstract: The reactor plate preferably includes a sealed reactor, a reactor flow channel connected to the reactor, a sample container constituted from a sealed container provided separately from the reactor, a sample container flow channel to be connected to the sample container, a syringe for sending a liquid, a switching valve for connecting the syringe to the reactor flow channel or the sample container flow channel, and a projecting flow channel connected to the end of the sample container flow channel located on the sample container side. The sample container has a penetrable portion through which the projecting flow channel can penetrate and which is provided to be opposed to the projecting flow channel and is located such that the projecting flow channel penetrating the penetrable portion is brought into contact with a liquid contained in the sample container. The sample container can be connected to the sample container flow channel.

Abstract: A microchip processing apparatus processes a microchip with at least one main separation channel. The microchip processing apparatus includes a holding part configured to hold the microchip, a container containing a sample or a reagent, and a dispensing probe having a needle formed on a tip of the dispensing probe. The dispensing probe is actuated to be inserted into the container from above the container, to draw the sample or reagent, and to inject to a prescribed position on the held microchip. A dispensing probe driving mechanism moves the dispensing probe between prescribed positions of the microchip and the container.

Abstract: In a separation buffer solution filling device, a microchip is arranged such reservoirs are opened on a surface on respective ends of channels including at least a main separation channel in which analysis is performed while a solution moves inside a plate-like member, and the reservoirs face upward. The filling device fills separation buffer solution into the channels by supplying air from an air supply port which is pushed while maintaining air-tightness onto a top of the reservoir filled with the separation buffer solution on either end of said channels. The air supply port is an opening on a front end of an air cylinder, and has a seal part on that opening. The filling device is pushed onto the reservoir while maintaining air-tightness by that seal part.

Abstract: Disclosed herein is a dispensing device capable of reducing the dead volume of a liquid sample. The dispensing device includes a main channel (3) whose one end is connected to a sample inlet (13) and whose other end is connected to a sample outlet (15), and a plurality of branch channels (5) connected to the main channel (3). The branch channels (5) are each connected to different liquid reservoirs (7) at their ends located on the opposite side from the main channel (3). A plurality of high inflow-withstanding pressure sections (17) having a higher inflow-withstanding pressure than the branch channel (5) are provided in the main channel (3) between the branch channels (5) and (5) and between the branch channel (5) and the sample outlet (15). Each of the high inflow-withstanding pressure sections (17) has a channel inner wall which forms a contact angle of 90° or larger with a liquid sample.

Abstract: Disclosed herein is a reactor plate which prevents the entry of foreign matter from the outside and the pollution of a surrounding environment. A reactor plate (1) includes a reaction well (5), a reaction well channel connected to the reaction well (5), and reaction well air vent channels (19) and (21) connected to the reaction well (5). The reaction well channel has a main channel (13), a metering channel (15) branched off the main channel (13), and an injection channel (17) of which one end is connected to the metering channel (15) and the other end is connected to the reaction well (5). The main channel (13) and the reaction well air vent channel (21) can be hermetically sealed.

Abstract: Micro droplets are accurately placed in a reaction well. The reaction well (5) is formed in one surface of a well base (3). A channel base (11) is placed on the well base (3). The channel base (11) has, in its surface joined to the well base (3), a liquid introduction channel (12a) and a reaction well air vent channel (18a). The channel base (11) also has a recess (27) formed opposite to the reaction well (5) and recessed upward from the upper surface of the liquid introduction channel (12a). When viewed from above, a shoulder part (26) of the recess (27) is placed near the connection part between the reaction well (5) and the liquid introduction channel (12a) and is closer to the center of the reaction well (5) than a shoulder part (16) of the reaction well (5).

Abstract: Methods and apparatuses for dispensing samples or reagents onto a target object are provided. A dispensing position designating section (62) designates the dispensing position on the target object (50), such as a membrane, based on an image of the target object (50) displayed on a monitoring section (60). A dispensing control section (64) positions the target object and the dispensing device relative to each other so that the designated dispensing position on the target object is placed beneath the dispensing device (10) and controls the dispensing operation of the dispensing device (10). A dispensing position information creating section (68) creates dispensing position information about the dispensing position on the target object (50) which is designated by the dispensing position designating section (62) and to which the dispensing operation has been performed and outputs it to the outside.

Abstract: It is intended to easily dispense a minute amount of nonvolatile liquid. In a preferred embodiment, in dispensing of mineral oil (nonvolatile liquid), dispensing is conducted in the condition that the amount of air contained in a tip (70) is small by aspirating a larger amount of mineral oil (40) than a single dispensing amount in the tip (70) of a nozzle (28).

Abstract: Disclosed is a reaction kit for preventing the entry of foreign matter into a reaction plate from the outside and the pollution of a surrounding environment. The reaction kit includes: a reaction plate (2) having, on the top surface side thereof, a reaction container (4) for carrying out the reaction of a sample and a reagent container (12) containing a reagent used for the reaction of a sample and sealed with a film (14); a dispensation tip (20) arranged on the top surface side of the reaction plate (2); a cover (24) covering a space above the top surface of the reaction plate (2) and movably supporting the dispensation tip (20) so that a distal end thereof is located inside the space covered with the cover (4) and a proximal end thereof is located outside the space; and a sample container (32) for introducing a sample into the space covered with the cover (24) from the outside through a sealable opening (31) provided in a part of the cover (24).

Abstract: Upper space on the front surface side of a reaction plate, provided with at least a reaction container causing reaction in a sample and a reagent container containing a reagent used for reaction with the sample, is covered with an airtight cover. A dispensation tip (20) for transporting liquid on the reaction plate is arranged in such a way that the distal end side is located on the inside of the covered space and the proximal portion is located on the outside.

Abstract: It is intended to facilitate dispensing of a minute amount of a nonvolatile liquid. In a preferred embodiment, in dispensing of mineral oil (40) onto a reaction solution (170) that is previously dispensed to a probe arrangement part (18), a liquid droplet (40a) of the mineral oil (40) is formed on a tip end of a tip (70) of the nozzle, and the liquid droplet (40a) is transferred into the reaction well while it is in contact with the inner wall face of the reaction well or the surface of the reaction solution (170) previously dispensed to the reaction well.

Abstract: Disclosed herein is a reactor plate which prevents the entry of foreign matter from outside and the pollution of an outside environment. The reactor plate includes a sealed reaction well (5), reaction well channels (13, 15, 17) connected to the reaction well (5), and a syringe (51) for sending a liquid to the reaction well channels (13, 15, 17) and the reaction well (5). The syringe (51) has a cylinder (51a), a plunger (51b), and a cover body (51d). The cover body (51d) has flexibility in the sliding direction of the plunger (51b), and is connected to the cylinder (51a) and the plunger (51b) to create a sealed space (51e) enclosed with the cylinder (51a), the plunger (51b), and the cover body (51d). The cover body (51d) is provided to hermetically cut off a part of an inner wall of the cylinder (51a) to be brought into contact with the plunger (51b) from an atmosphere outside the cylinder (51a).

Abstract: Intrusion of foreign matters from the outside of a reaction container plate and environmental contamination onto the outside are prevented. The reaction container plate (1) comprises a container base (3) having a reaction container (5), a channel base (11) having an introduction hole (11b) above the reaction container (5) and arranged on the surface of the container base (3), and a channel cover (13) arranged on the channel base (11) in order to form in cooperation with the surface of the channel base, an introduction channel (15) passing above the introduction hole (11b). The channel (13) is formed to be enclosed. The introduction hole (11b) does not allow liquid to pass under an introduction pressure state in the channel (15) where the liquid is introduced into the channel (15) but allows the liquid in the channel (15) to pass to the reaction container (5) side under a pressurized state where the inside of the channel (15) is pressurized higher than the introduction pressure.

Abstract: The processing apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips so that the multiple main flow paths are provided; a pretreatment part common to the multiple main flow paths for performing a pretreatment step prior to an analysis step in each of the multiple main flow paths; a processing part for performing analysis in each of the main flow paths independently of the others; and a control part controlling an operation in the pretreatment part so that when a pretreatment step for one main flow path ends, a pretreatment for a next main flow path starts and further controlling an operation in the processing part so that an analysis is subsequently performed for the main flow path where the pretreatment step has ended.

Abstract: Disclosed herein is a reactor plate which prevents the entry of foreign matter from the outside and the pollution of an outside environment. The reactor plate includes sealed reaction wells (5), reaction well channels (13, 15, 17) connected to the reaction wells (5), a sealed well (35) provided separately from the reaction wells (5), a sealed well channel (35a) connected to the sealed well (35), a syringe (51) for sending a liquid, a syringe channel (51c) connected to the syringe (51), and a rotary switching valve (63) for connecting the syringe channel (51c) to the reaction well channel (13) or the sealed well channel (35a). The sealed well channel (35a) is openably sealed with the rotary switching valve (63) at an end thereof not connected to the sealed well (35). Therefore, even when the sealed well (35) previously contains a liquid, foreign matter does not enter the sealed well (35) from the outside and leakage of the liquid contained in the sealed well (35) to the outside does not occur.