Patents by Inventor Nobuyuki Itoh
Nobuyuki Itoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7723297Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.Type: GrantFiled: April 17, 2006Date of Patent: May 25, 2010Assignees: Kyoto University, Novartis Vaccines and Diagnostics, Inc.Inventors: Nobuyuki Itoh, Michael Kavanaugh
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Publication number: 20090074776Abstract: This invention relates to human fibroblast growth factor (hF-GF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.Type: ApplicationFiled: August 16, 2007Publication date: March 19, 2009Applicants: Novartis Vaccines and Diagnostics, Kyoto UniversityInventors: Nobuyuki Itoh, Michael Kavanaugh
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Publication number: 20080309423Abstract: A voltage control oscillator has a first MOS transistor having one end connected to a first potential; a second MOS transistor having one end connected to the first potential, a gate connected to an other end of the first MOS transistor, and an other end connected to a gate of the first MOS transistor; a first varactor having one end connected to the other end of the first MOS transistor, an other end connected to the other end of the second MOS transistor, and a capacitance changing with a first control voltage; a first inductor having one end connected to the one end of the first varactor; a second inductor having one end connected to the other end of the first varactor; a second varactor having one end connected to an other end of the first inductor, an other end connected to an other end of the second inductor, and a capacitance changing with a second control voltage; a third inductor connected between the one end of the second varactor and a second potential; and a fourth inductor connected between the oType: ApplicationFiled: June 12, 2008Publication date: December 18, 2008Inventors: Nobuyuki ITOH, Chiharu Nakajima
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Patent number: 7381509Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.Type: GrantFiled: August 28, 2007Date of Patent: June 3, 2008Assignee: Canon Kabushiki KaishaInventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
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Publication number: 20080050670Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.Type: ApplicationFiled: August 28, 2007Publication date: February 28, 2008Applicant: CANON KABUSHIKI KAISHAInventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
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Patent number: 7288356Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.Type: GrantFiled: November 18, 2004Date of Patent: October 30, 2007Assignee: Canon Kabushiki KaishaInventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
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Publication number: 20070238657Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.Type: ApplicationFiled: April 17, 2006Publication date: October 11, 2007Applicant: Novartis Vaccines and Diagnostics, Inc.Inventors: Nobuyuki Itoh, Michael Kavanaugh
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Patent number: 7259248Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.Type: GrantFiled: January 29, 2002Date of Patent: August 21, 2007Assignees: Chiron Corporation, Kyoto UniversityInventors: Nobuyuki Itoh, W Michael Kavanaugh
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Publication number: 20070128619Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-2 1. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.Type: ApplicationFiled: May 26, 2006Publication date: June 7, 2007Applicants: Novartis Vaccines and Diagnostics, Kyoto UniversityInventors: Nobuyuki Itoh, Michael Kavanaugh
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Patent number: 7221920Abstract: A voltage controlled oscillator includes a resonator configured to resonate with an initial oscillation frequency during starting period of oscillation and a steady oscillation frequency during a steady state oscillation. The resonator includes a film bulk acoustic resonator having a series resonance frequency higher than the steady oscillation frequency. A negative resistance circuit configured to drive the resonator, has a positive increment for reactance in the steady state oscillation compared with reactance in the starting period.Type: GrantFiled: July 15, 2004Date of Patent: May 22, 2007Assignee: Kabushiki Kaisha ToshibaInventors: Kazuhide Abe, Mayumi Morizuka, Ryoichi Ohara, Kenya Sano, Naoko Yanase, Takaaki Yasumoto, Tadahiro Sasaki, Kazuhiko Itaya, Takashi Kawakubo, Hiroshi Yoshida, Ryuichi Fujimoto, Keiichi Yamaguchi, Nobuyuki Itoh, Tooru Kozu, Takeshi Ookubo
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Publication number: 20060290855Abstract: A liquid crystal display apparatus includes: a pair of substrates opposing each other; a liquid crystal layer interposed between the pair of substrates, the liquid crystal layer containing liquid crystal molecules having a negative dielectric anisotropy; at least one electrode provided on each of the pair of substrates, the at least one electrode being used for applying an electric field across the liquid crystal layer; and at least one volume excluding member. One of the at least one volume excluding member is provided on the at least one electrode on at least one of the pair of substrates, the volume excluding member being provided so as to be on at least a portion of one side edge of the at least one electrode. A side of each of the pair of substrates facing the liquid crystal layer is subjected to a vertical alignment treatment.Type: ApplicationFiled: August 31, 2006Publication date: December 28, 2006Applicant: Sharp Kabushiki KaishaInventors: Nobuyuki Itoh, Akira Tagawa, Masaaki Kabe, Tomoo Furukawa
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Publication number: 20060281679Abstract: This invention relates to human fibroblast growth factor (hFGF-23), to cleavage products of hFGF-23, and to variants thereof and to polynucleotides encoding FGF-23. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating skin, brain and placental disease and disorders, and methods of treating conditions related to thymic function. The invention also relates to mouse fibroblast growth factor (mFGF-23), and to variants thereof and polynucleotides encoding mFGF-23.Type: ApplicationFiled: December 28, 2005Publication date: December 14, 2006Inventors: Nobuyuki Itoh, W. Kavanaugh
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Publication number: 20060172386Abstract: This invention relates to human fibroblast growth factor (hFGF-20), and to variants thereof and to polynucleotides encoding FGF-20. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, to methods of treating neuronal degenerative disease such as Parkinson's disease and to methods of treating disorders of the cochlea including those causing hearing loss. The invention also relates to rat fibroblast growth factor (rFGF-20), and to variants thereof and polynucleotides encoding rFGF-20.Type: ApplicationFiled: December 27, 2005Publication date: August 3, 2006Applicant: Chiron CorporationInventors: Nobuyuki Itoh, Michael Kavanaugh
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Patent number: 6996358Abstract: A color image forming apparatus forms an image using a deep toner and a pale toner at least for one color such that the pale toner is used to form an image in a high lightness area, and the pale toner and the deep toner are used in combination to form the image in a half tone area. A toner kit has a deep toner and a pale toner which are separated from each other. A method for forming an image uses the color image forming apparatus, the toner kit, and the deep toner and the pale toner. A high quality image can be formed while inhibiting graininess and roughness over a broad image area.Type: GrantFiled: May 20, 2003Date of Patent: February 7, 2006Assignee: Canon Kabushiki KaishaInventors: Yasukazu Ayaki, Takeshi Ikeda, Yukio Nagase, Nobuyuki Itoh, Isami Itoh, Tomohito Ishida
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Publication number: 20050106481Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.Type: ApplicationFiled: November 18, 2004Publication date: May 19, 2005Applicant: CANON KABUSHIKI KAISHAInventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
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Publication number: 20050059375Abstract: A voltage controlled oscillator includes a resonator configured to resonate with an initial oscillation frequency during starting period of oscillation and a steady oscillation frequency during a steady state oscillation. The resonator includes a film bulk acoustic resonator having a series resonance frequency higher than the steady oscillation frequency. A negative resistance circuit configured to drive the resonator, has a positive increment for reactance in the steady state oscillation compared with reactance in the starting period.Type: ApplicationFiled: July 15, 2004Publication date: March 17, 2005Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Kazuhide Abe, Mayumi Morizuka, Ryoichi Ohara, Kenya Sano, Naoko Yanase, Takaaki Yasumoto, Tadahiro Sasaki, Kazuhiko Itaya, Takashi Kawakubo, Hiroshi Yoshida, Ryuichi Fujimoto, Keiichi Yamaguchi, Nobuyuki Itoh, Tooru Kozu, Takeshi Ookubo
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Publication number: 20050037457Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.Type: ApplicationFiled: February 3, 2004Publication date: February 17, 2005Applicant: Chiron CorporationInventors: Nobuyuki Itoh, Michael Kavanaugh
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Patent number: 6803932Abstract: Provided is an image forming apparatus for forming a toner image including: a first light source emitting a beam corresponding to image information; a first photosensitive member; a first developing means for developing a latent image with a first toner; a second light source; a second photosensitive member; and a second developing means for developing a latent image with a second toner, in which the coloring agent contained in the first toner and the coloring agent contained in the second toner are substantially of the same hue, with the content of the coloring agent contained in the second toner being smaller than the content of the coloring agent contained in the first toner, and in which an oscillation wavelength of at least the first light source ranges from 370 to 500 nm. With the image forming apparatus structured as described above, an improvement in terms of granularity is achieved.Type: GrantFiled: August 22, 2003Date of Patent: October 12, 2004Assignee: Canon Kabushiki KaishaInventors: Isami Itoh, Takeshi Ikeda, Yukio Nagase, Nobuyuki Itoh, Yasukazu Ayaki, Tomohito Ishida
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Patent number: 6797695Abstract: This invention relates to human fibroblast growth factor (hFGF-20), and to variants thereof and to polynucleotides encoding FGF-20. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, to methods of treating neuronal degenerative disease such as Parkinson's disease and to methods of treating disorders of the cochlea including those causing hearing loss. The invention also relates to rat fibroblast growth factor (rFGF-20), and to variants thereof and polynucleotides encoding rFGF-20.Type: GrantFiled: October 20, 2000Date of Patent: September 28, 2004Assignees: Kyoto University, Chiron CorporationInventors: Nobuyuki Itoh, Michael Kavanaugh
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Publication number: 20040185494Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.Type: ApplicationFiled: April 5, 2004Publication date: September 23, 2004Applicant: Chiron CorporationInventors: Nobuyuki Itoh, Michael Kavanaugh