Patents by Inventor Nobuyuki Itoh

Nobuyuki Itoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7723297
    Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: May 25, 2010
    Assignees: Kyoto University, Novartis Vaccines and Diagnostics, Inc.
    Inventors: Nobuyuki Itoh, Michael Kavanaugh
  • Publication number: 20090074776
    Abstract: This invention relates to human fibroblast growth factor (hF-GF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
    Type: Application
    Filed: August 16, 2007
    Publication date: March 19, 2009
    Applicants: Novartis Vaccines and Diagnostics, Kyoto University
    Inventors: Nobuyuki Itoh, Michael Kavanaugh
  • Publication number: 20080309423
    Abstract: A voltage control oscillator has a first MOS transistor having one end connected to a first potential; a second MOS transistor having one end connected to the first potential, a gate connected to an other end of the first MOS transistor, and an other end connected to a gate of the first MOS transistor; a first varactor having one end connected to the other end of the first MOS transistor, an other end connected to the other end of the second MOS transistor, and a capacitance changing with a first control voltage; a first inductor having one end connected to the one end of the first varactor; a second inductor having one end connected to the other end of the first varactor; a second varactor having one end connected to an other end of the first inductor, an other end connected to an other end of the second inductor, and a capacitance changing with a second control voltage; a third inductor connected between the one end of the second varactor and a second potential; and a fourth inductor connected between the o
    Type: Application
    Filed: June 12, 2008
    Publication date: December 18, 2008
    Inventors: Nobuyuki ITOH, Chiharu Nakajima
  • Patent number: 7381509
    Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: June 3, 2008
    Assignee: Canon Kabushiki Kaisha
    Inventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
  • Publication number: 20080050670
    Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.
    Type: Application
    Filed: August 28, 2007
    Publication date: February 28, 2008
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
  • Patent number: 7288356
    Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: October 30, 2007
    Assignee: Canon Kabushiki Kaisha
    Inventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
  • Publication number: 20070238657
    Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
    Type: Application
    Filed: April 17, 2006
    Publication date: October 11, 2007
    Applicant: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Nobuyuki Itoh, Michael Kavanaugh
  • Patent number: 7259248
    Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: August 21, 2007
    Assignees: Chiron Corporation, Kyoto University
    Inventors: Nobuyuki Itoh, W Michael Kavanaugh
  • Publication number: 20070128619
    Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-2 1. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
    Type: Application
    Filed: May 26, 2006
    Publication date: June 7, 2007
    Applicants: Novartis Vaccines and Diagnostics, Kyoto University
    Inventors: Nobuyuki Itoh, Michael Kavanaugh
  • Patent number: 7221920
    Abstract: A voltage controlled oscillator includes a resonator configured to resonate with an initial oscillation frequency during starting period of oscillation and a steady oscillation frequency during a steady state oscillation. The resonator includes a film bulk acoustic resonator having a series resonance frequency higher than the steady oscillation frequency. A negative resistance circuit configured to drive the resonator, has a positive increment for reactance in the steady state oscillation compared with reactance in the starting period.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: May 22, 2007
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Kazuhide Abe, Mayumi Morizuka, Ryoichi Ohara, Kenya Sano, Naoko Yanase, Takaaki Yasumoto, Tadahiro Sasaki, Kazuhiko Itaya, Takashi Kawakubo, Hiroshi Yoshida, Ryuichi Fujimoto, Keiichi Yamaguchi, Nobuyuki Itoh, Tooru Kozu, Takeshi Ookubo
  • Publication number: 20060290855
    Abstract: A liquid crystal display apparatus includes: a pair of substrates opposing each other; a liquid crystal layer interposed between the pair of substrates, the liquid crystal layer containing liquid crystal molecules having a negative dielectric anisotropy; at least one electrode provided on each of the pair of substrates, the at least one electrode being used for applying an electric field across the liquid crystal layer; and at least one volume excluding member. One of the at least one volume excluding member is provided on the at least one electrode on at least one of the pair of substrates, the volume excluding member being provided so as to be on at least a portion of one side edge of the at least one electrode. A side of each of the pair of substrates facing the liquid crystal layer is subjected to a vertical alignment treatment.
    Type: Application
    Filed: August 31, 2006
    Publication date: December 28, 2006
    Applicant: Sharp Kabushiki Kaisha
    Inventors: Nobuyuki Itoh, Akira Tagawa, Masaaki Kabe, Tomoo Furukawa
  • Publication number: 20060281679
    Abstract: This invention relates to human fibroblast growth factor (hFGF-23), to cleavage products of hFGF-23, and to variants thereof and to polynucleotides encoding FGF-23. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating skin, brain and placental disease and disorders, and methods of treating conditions related to thymic function. The invention also relates to mouse fibroblast growth factor (mFGF-23), and to variants thereof and polynucleotides encoding mFGF-23.
    Type: Application
    Filed: December 28, 2005
    Publication date: December 14, 2006
    Inventors: Nobuyuki Itoh, W. Kavanaugh
  • Publication number: 20060172386
    Abstract: This invention relates to human fibroblast growth factor (hFGF-20), and to variants thereof and to polynucleotides encoding FGF-20. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, to methods of treating neuronal degenerative disease such as Parkinson's disease and to methods of treating disorders of the cochlea including those causing hearing loss. The invention also relates to rat fibroblast growth factor (rFGF-20), and to variants thereof and polynucleotides encoding rFGF-20.
    Type: Application
    Filed: December 27, 2005
    Publication date: August 3, 2006
    Applicant: Chiron Corporation
    Inventors: Nobuyuki Itoh, Michael Kavanaugh
  • Patent number: 6996358
    Abstract: A color image forming apparatus forms an image using a deep toner and a pale toner at least for one color such that the pale toner is used to form an image in a high lightness area, and the pale toner and the deep toner are used in combination to form the image in a half tone area. A toner kit has a deep toner and a pale toner which are separated from each other. A method for forming an image uses the color image forming apparatus, the toner kit, and the deep toner and the pale toner. A high quality image can be formed while inhibiting graininess and roughness over a broad image area.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: February 7, 2006
    Assignee: Canon Kabushiki Kaisha
    Inventors: Yasukazu Ayaki, Takeshi Ikeda, Yukio Nagase, Nobuyuki Itoh, Isami Itoh, Tomohito Ishida
  • Publication number: 20050106481
    Abstract: The present invention provides: a toner kit having a deep toner and a pale toner which are separated from each other, wherein: the deep toner and the pale toner satisfy prescribed conditions for an L*a*b* color coordinate system where a* represents a hue in the red-green direction, b* represents a hue in the yellow-blue direction, and L* represents a lightness; the pale toner and the deep toner to be used in the toner kit; and a method for forming an image using the toner kit. Thus, the present invention can form a high quality image, while suppressing graininess and roughness over the areas covering from the low density area to the high density area.
    Type: Application
    Filed: November 18, 2004
    Publication date: May 19, 2005
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Yasukazu Ayaki, Takeshi Ikeda, Tomohito Ishida, Nobuyuki Itoh
  • Publication number: 20050059375
    Abstract: A voltage controlled oscillator includes a resonator configured to resonate with an initial oscillation frequency during starting period of oscillation and a steady oscillation frequency during a steady state oscillation. The resonator includes a film bulk acoustic resonator having a series resonance frequency higher than the steady oscillation frequency. A negative resistance circuit configured to drive the resonator, has a positive increment for reactance in the steady state oscillation compared with reactance in the starting period.
    Type: Application
    Filed: July 15, 2004
    Publication date: March 17, 2005
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Kazuhide Abe, Mayumi Morizuka, Ryoichi Ohara, Kenya Sano, Naoko Yanase, Takaaki Yasumoto, Tadahiro Sasaki, Kazuhiko Itaya, Takashi Kawakubo, Hiroshi Yoshida, Ryuichi Fujimoto, Keiichi Yamaguchi, Nobuyuki Itoh, Tooru Kozu, Takeshi Ookubo
  • Publication number: 20050037457
    Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
    Type: Application
    Filed: February 3, 2004
    Publication date: February 17, 2005
    Applicant: Chiron Corporation
    Inventors: Nobuyuki Itoh, Michael Kavanaugh
  • Patent number: 6803932
    Abstract: Provided is an image forming apparatus for forming a toner image including: a first light source emitting a beam corresponding to image information; a first photosensitive member; a first developing means for developing a latent image with a first toner; a second light source; a second photosensitive member; and a second developing means for developing a latent image with a second toner, in which the coloring agent contained in the first toner and the coloring agent contained in the second toner are substantially of the same hue, with the content of the coloring agent contained in the second toner being smaller than the content of the coloring agent contained in the first toner, and in which an oscillation wavelength of at least the first light source ranges from 370 to 500 nm. With the image forming apparatus structured as described above, an improvement in terms of granularity is achieved.
    Type: Grant
    Filed: August 22, 2003
    Date of Patent: October 12, 2004
    Assignee: Canon Kabushiki Kaisha
    Inventors: Isami Itoh, Takeshi Ikeda, Yukio Nagase, Nobuyuki Itoh, Yasukazu Ayaki, Tomohito Ishida
  • Patent number: 6797695
    Abstract: This invention relates to human fibroblast growth factor (hFGF-20), and to variants thereof and to polynucleotides encoding FGF-20. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, to methods of treating neuronal degenerative disease such as Parkinson's disease and to methods of treating disorders of the cochlea including those causing hearing loss. The invention also relates to rat fibroblast growth factor (rFGF-20), and to variants thereof and polynucleotides encoding rFGF-20.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: September 28, 2004
    Assignees: Kyoto University, Chiron Corporation
    Inventors: Nobuyuki Itoh, Michael Kavanaugh
  • Publication number: 20040185494
    Abstract: This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
    Type: Application
    Filed: April 5, 2004
    Publication date: September 23, 2004
    Applicant: Chiron Corporation
    Inventors: Nobuyuki Itoh, Michael Kavanaugh