Patents by Inventor Nong Zhang

Nong Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210285857
    Abstract: A device and method for testing the working performance of an anchor rod cable by simulating stratum fracture and separation on the basis of electromagnetic action, applicable to the technical field of testing working performance of anchor rod cables by simulating a tunnel field. The device comprises a top base (1) and a bottom base (2); a plurality of hydraulic vertical columns (3) are provided between the top base (1) and the bottom base (2); the plurality of hydraulic vertical columns (3) are provided thereon with clamping devices, and an electromagnetic block (9) is disposed between two groups of drawing block-shaped clamp holders (4).
    Type: Application
    Filed: September 13, 2018
    Publication date: September 16, 2021
    Inventors: Nong ZHANG, Zhengzheng XIE, Junyao ZHOU, Yuxin YUAN, Xinyue LI
  • Publication number: 20210270134
    Abstract: A method for operating a continuous mining machine having a device continuously providing provisional roof support, wherein the mining machine a rolling roof-protection portion which is fixed on a main machine frame of the continuous mining machine via a front column structure and a rear column structure. While the machine is cutting, the roof-protection device performs continuous load holding on a roof, and after cutting, performs support operations, thereby achieving simultaneous performance of cutting and support operations, and improving tunneling efficiency. Different support strengths are configured according to the hardness, completeness, and quality indicators of rock on a mine roof, such that the device is able to effectively support the roof.
    Type: Application
    Filed: October 29, 2018
    Publication date: September 2, 2021
    Inventors: Nong ZHANG, Zhengzheng XIE, Qun WEI, Junyao ZHOU
  • Patent number: 11078021
    Abstract: A steel belt conveying apparatus includes upper and lower horizontal conveying portions, left and right inclined conveying chains, a connecting rod frame, an inclined frame, a drive portion, and a height adjustment cylinder. The left inclined conveying chain is separately connected to the upper and lower horizontal conveying portions. The right inclined conveying chain is separately connected to the upper and lower horizontal conveying portions. A top portion of the connecting rod frame is hingedly connected to an upper horizontal frame of the upper horizontal conveying portion. A bottom portion is hingedly connected to a lower frame of the lower horizontal conveying portion. A top portion of the inclined frame is hingedly connected to an upper horizontal drive shaft of the upper horizontal conveying portion, and a bottom portion is hingedly connected to a lower horizontal drive shaft of the lower horizontal conveying portion.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: August 3, 2021
    Assignee: CHINA UNIVERSITY OF MINING AND TECHNOLOGY
    Inventors: Nong Zhang, Zhengzheng Xie, Junyao Zhou, Qun Wei
  • Patent number: 11078192
    Abstract: Disclosed are an aromatic acetylene or aromatic ethylene compound, an intermediate, a preparation method, a pharmaceutical composition and a use thereof. The aromatic acetylene or aromatic ethylene compound has a significant inhibitory effect on PD-1 and PD-L1, and can effectively relieve or treat cancers and other related diseases.
    Type: Grant
    Filed: July 4, 2017
    Date of Patent: August 3, 2021
    Inventors: Yuguang Wang, Zusheng Xu, Tianzhi Wu, Min He, Nong Zhang
  • Publication number: 20210222553
    Abstract: An apparatus for controllably unfolding a flexible mesh for a continuous miner includes a mesh roll storage rack, a height adjustment post, a mesh rolling shaft and a flexible mesh. The flexible mesh includes a mesh roll and an unfolded mesh. The mesh roll and the unfolded mesh are an integrated structure. The mesh roll is located on the mesh roll storage rack. The unfolded mesh is clamped on the mesh rolling shaft, and is pressed on a cut un-supported tunnel roof via a roof bolt. The mesh rolling shaft is rotatably connected to a top portion of the height adjustment post. The mesh roll storage rack and the height adjustment post are both mounted on the continuous miner. The mesh rolling shaft is located at a back end of the mesh roll storage rack. A limit mechanism and a damping mechanism are disposed on the mesh rolling shaft.
    Type: Application
    Filed: October 29, 2018
    Publication date: July 22, 2021
    Applicant: CHINA UNIVERSITY OF MINING AND TECHNOLOGY
    Inventors: Nong ZHANG, Zhengzheng XIE, Qun WEI, Junyao ZHOU
  • Patent number: 11066413
    Abstract: Disclosed in the present invention is an aminopyrimidine five-membered heterocyclic compound, and an intermediate, preparation method, pharmaceutical composition and application thereof. The aminopyrimidine five-membered heterocyclic compound provided by the present invention has a significant antagonistic effect on adenosine A2A receptors, and may be used as an antagonist for adenosine A2A receptors to effectively relieve or treat immune tolerance, diseases of the central nervous system, inflammatory diseases and like related diseases, while the preparation method is simple.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: July 20, 2021
    Assignee: GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.
    Inventors: Yuguang Wang, Nong Zhang, Tianzhi Wu
  • Publication number: 20210198046
    Abstract: A steel belt conveying apparatus includes upper and lower horizontal conveying portions, left and right inclined conveying chains, a connecting rod frame, an inclined frame, a drive portion, and a height adjustment cylinder. The left inclined conveying chain is separately connected to the upper and lower horizontal conveying portions. The right inclined conveying chain is separately connected to the upper and lower horizontal conveying portions. A top portion of the connecting rod frame is hingedly connected to an upper horizontal frame of the upper horizontal conveying portion. A bottom portion is hingedly connected to a lower frame of the lower horizontal conveying portion. A top portion of the inclined frame is hingedly connected to an upper horizontal drive shaft of the upper horizontal conveying portion, and a bottom portion is hingedly connected to a lower horizontal drive shaft of the lower horizontal conveying portion.
    Type: Application
    Filed: October 29, 2018
    Publication date: July 1, 2021
    Applicant: CHINA UNIVERSITY OF MINING AND TECHNOLOGY
    Inventors: Nong ZHANG, Zhengzheng XIE, Junyao ZHOU, Qun WEI
  • Publication number: 20210198275
    Abstract: Disclosed are a salt of a fused ring pyrimidine compound, a crystal form thereof and a preparation method therefor and the use thereof. The fused ring pyrimidine compound is N-[7-(4-fluoro-2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-1-(piperidin-4-yl)-1H-pyrazol-4-amine, having a structure as shown in formula 1. The preparation methods in the invention for the salt of the fused ring pyrimidine compound and the crystal form thereof are simple; and the salt of the fused ring pyrimidine compound and the crystal form thereof at least have the characteristics of having a better stability, not easily absorbing moisture, being of a polycrystalline type, having a chemical stability and pharmacokinetics, and having an improved solubility.
    Type: Application
    Filed: May 10, 2019
    Publication date: July 1, 2021
    Applicant: GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.
    Inventors: Yuguang WANG, Nong ZHANG, Pingjing ZHANG
  • Publication number: 20210189876
    Abstract: The present invention relates to a clean and efficient coal mining method, which is applicable to the field of solid waste treatment in mines.
    Type: Application
    Filed: March 13, 2018
    Publication date: June 24, 2021
    Inventors: Nong Zhang, Zhengzheng Xie, Junyao Zhou
  • Publication number: 20210061755
    Abstract: Disclosed in the present invention are an aromatic vinyl or aromatic ethyl derivative, a preparation method therefor, an intermediate, a pharmaceutical composition, and an application. The aromatic vinyl or aromatic ethyl derivative in the present invention is as represented by general formula (I). The aromatic vinyl or aromatic ethyl derivative in the present invention has an obvious inhibitory effect on PD-1/PD-L1, is a very effective small-molecule PD-1/PD-L1 inhibitor, and can effectively alleviate or treat relevant diseases such as cancer.
    Type: Application
    Filed: December 24, 2018
    Publication date: March 4, 2021
    Inventors: Yuguang WANG, Nong ZHANG, Tianzhi WU, Min HE
  • Patent number: 10907474
    Abstract: A reaming and self-rotating anchor rod includes a rod body, a drill bit, a connecting member, a tray, and a nut. One end the connecting member is snap-fixed to the tail part of the rod body, the other end of the connecting member is connected to an anchor rod bolter. The rod body has an annular protrusion at its middle part to block powder so that the powder fills up the clearance between the rod body and the coal mass. The drill bit has female threads and can be screwed into the front part of the rod body, and the drill bit has baffle pawls and spiral grooves on its side surface.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: February 2, 2021
    Assignee: China University of Mining and Technology
    Inventors: Nong Zhang, Zhengzheng Xie, Changliang Han
  • Publication number: 20200319069
    Abstract: Disclosed are an integral clamping steel strand drawing test apparatus, and a method for using same, wherein same are suitable for use in a steel strand mechanical property test. The apparatus comprises a rectangular lower base (13) and a rectangular upper base (14), with a hydraulic telescopic mechanism being provided between the lower base (13) and the upper base (14), the hydraulic telescopic mechanism being provided with an integral clamping mechanism, a steel strand test piece (4) to be tested being provided in the integral clamping mechanism, the steel strand test piece (4) to be tested being provided with a plurality of binding protective devices (2), and a safety protection door (16) being provided outside the hydraulic telescopic mechanism.
    Type: Application
    Filed: September 13, 2018
    Publication date: October 8, 2020
    Inventors: Nong Zhang, Zhengzheng Xie, Junyao Zhou, Zhe Xiang, Xinyue Li
  • Patent number: 10767480
    Abstract: Provided is a mounting method for an extensible reaming self-anchoring anchor rod, which is especially applicable to roadway construction in coal mines. A big helical structure is arranged on two rod sections of a sectional type anchor rod, a simple drill bit drills and reams a bore and cuts the coal mass in one operation, the outer diameter of the simple drill bit is smaller than the outer diameter of the big helical rod body, and the big helical structure accomplishes secondary reaming, self-drilling and self-anchoring in the drilling process; the big helical structure inhibits propagation and development of sheet cracks of the coal wall in the radial direction, and is embedded in the coal mass through a self-stabilization process of the rock mass.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: September 8, 2020
    Assignee: CHINA UNIVERSITY OF MINING AND TECHNOLOGY
    Inventors: Nong Zhang, Peng Ma, Changliang Han, Zhengzheng Xie
  • Publication number: 20200248552
    Abstract: The present invention provides a reaming and self-rotating anchor rod and a construction method using the reaming and self-rotating anchor rod, which are applicable to supporting for quick tunneling of coal roadways.
    Type: Application
    Filed: June 7, 2017
    Publication date: August 6, 2020
    Inventors: Nong ZHANG, Zhengzheng XIE
  • Publication number: 20200217201
    Abstract: Provided is a mounting method for an extensible reaming self-anchoring anchor rod, which is especially applicable to roadway construction in coal mines. A big helical structure is arranged on two rod sections of a sectional type anchor rod, a simple drill bit drills and reams a bore and cuts the coal mass in one operation, the outer diameter of the simple drill bit is smaller than the outer diameter of the big helical rod body, and the big helical structure accomplishes secondary reaming, self-drilling and self-anchoring in the drilling process; the big helical structure inhibits propagation and development of sheet cracks of the coal wall in the radial direction, and is embedded in the coal mass through a self-stabilization process of the rock mass.
    Type: Application
    Filed: June 7, 2017
    Publication date: July 9, 2020
    Inventors: Nong ZHANG, Peng MA, Changliang HAN, Zhengzheng XIE
  • Patent number: 10611770
    Abstract: Disclosed are a condensed-ring pyrimidylamino derivative, a preparation method therefor, and an intermediate, a pharmaceutical composition and applications thereof. The method for preparing the condensed-ring pyrimidylamino derivative comprises: in a solvent, in the presence of a palladium-containing catalyst, allowing a compound represented by formula I-a and a compound represented by formula I-b? to have a coupling reaction, and then preparing a compound represented by formula I by means of a deprotection reaction. Also disclosed applications of the condensed-ring pyrimidylamino derivative in the preparation of drugs for preventing, relieving and/or treating tumors or diseases caused by an anaplastic lymphoma kinase. The condensed-ring pyrimidylamino derivative of the present invention has an obvious restraint effect on the anaplastic lymphoma kinase.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: April 7, 2020
    Assignee: GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.
    Inventors: Nong Zhang, Zusheng Xu, Tinghan Wang, Yuguang Wang
  • Publication number: 20200048270
    Abstract: Disclosed in the present invention is an aminopyrimidine five-membered heterocyclic compound, and an intermediate, preparation method, pharmaceutical composition and application thereof. The aminopyrimidine five-membered heterocyclic compound provided by the present invention has a significant antagonistic effect on adenosine A2A receptors, and may be used as an antagonist for adenosine A2A receptors to effectively relieve or treat immune tolerance, diseases of the central nervous system, inflammatory diseases and like related diseases, while the preparation method is simple.
    Type: Application
    Filed: March 7, 2018
    Publication date: February 13, 2020
    Inventors: Yuguang WANG, Nong ZHANG, Tianzhi WU
  • Patent number: 10494378
    Abstract: Disclosed area fused ring pyrimidine compound, and an intermediate, a preparation method, a composition and a use thereof. The fused ring pyrimidine compound is a compound as shown in formula I, a tautomer, an enantiomer, a diastereoisomer, a pharmaceutically acceptable salt, a metabolite, a metabolic precursor or a prodrug thereof, wherein the above-mentioned compound is used for the preparation of a medicine for preventing, remitting or treating one or more of immune system diseases, autoimmune diseases, cell proliferative diseases, allergic disorders and cardiovascular diseases, and the compound has a strong inhibitory effect on the Janues kinase, FGFR kinase, FLT3 kinase and Src family kinase.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: December 3, 2019
    Assignee: GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.
    Inventors: Zusheng Xu, Nong Zhang, Tinghan Wang, Qingrui Sun, Yuguang Wang
  • Patent number: 10487654
    Abstract: The present invention provides a self-drilling and self-anchoring extendable anchor rod applicable to soft and weak coal rocks and an anchoring method thereof, which are suitable for supporting soft and weak coal rock mass in roadways.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: November 26, 2019
    Assignee: CHINA UNIVERSITY OF MINING AND TECHNOLOGY
    Inventors: Nong Zhang, Changliang Han, Ke Yang, Zhengzheng Xie
  • Publication number: 20190308957
    Abstract: Disclosed are an aromatic acetylene or aromatic ethylene compound, an intermediate, a preparation method, a pharmaceutical composition and a use thereof. The aromatic acetylene or aromatic ethylene compound has a significant inhibitory effect on PD-1 and PD-L1, and can effectively relieve or treat cancers and other related diseases.
    Type: Application
    Filed: July 4, 2017
    Publication date: October 10, 2019
    Applicant: Guangzhou Maxinovel Pharmaceuticals Co., Ltd
    Inventors: Yuguang WANG, Zusheng XU, Tianzhi WU, Min HE, Nong ZHANG