Abstract: The present invention relates to substituted chromanol derivatives, to processes for their preparation, to their use on their own or in combination for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.

Abstract: A valve assembly for use in an air management assembly having an engine, an exhaust side, and an intake side, where the valve assembly provides a housing, a plurality of openings in the housing, a valve in the housing, and an actuator operably connected to the valve. The housing is in fluid communication with the exhaust side and the intake side. The plurality of openings in the housing form at least one inlet and at least one outlet in the housing. The valve moves with respect to the plurality of openings.

Abstract: The present invention relates to pharmaceutical compositions for treating virus infections and/or diseases caused by virus infections comprising at least a diaryl urea compound optionally combined with at least one additional therapeutic agent. Useful combinations include e.g. BAY 43-9006 as a diaryl urea compound.

Abstract: An air management assembly (10) for use in an engine (12) with an exhaust manifold (14) that outputs an exhaust gas and an intake manifold (16), with a filter (18) in fluid communication between the exhaust manifold (14) and turbocharger (20). The air management assembly (10) provides a compressor (22), a turbine (24), at least one gaseous fluid cooler (32, 36, 44), at least one bypass (28, 28)? and a housing (30) where the compressor (22), turbine (24), at least one gaseous fluid cooler (32), (36, 44), bypass (28, 28), or combination thereof are integrated into the housing (30). The compressor (22) is in fluid communication with the intake manifold (16). The turbine (24) is in fluid communication with the exhaust manifold (14). The turbine (24) and the compressor (22) are moveably coupled and move in conjunction with one another. The gaseous fluid coolers (32, 36, 44) are in fluid communication with the compressor (32), turbine (24), or combination thereof.

Abstract: The present application relates to novel tricyclic benzazepine derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.

Abstract: A turbocharger arrangement providing a turbocharger, at least one treatment device, and at least one boost device. The turbocharger has a turbine and a compressor that are moveably coupled to one another. The turbine has an upstream path and a downstream path. The compressor has an upstream path and a downstream path. The at least one treatment device is in fluid communication with the upstream path of the turbine. The at least one additional boost device is operably engaged with the turbocharger to assist the flow of a gaseous fluid through the at least one treatment device and the turbocharger.

Abstract: The invention relates to compounds of the formule

Abstract: The present invention is a an exhaust gas return system (10) for reintroducing condensate generated in exhaust gas from an engine (14) into a compressor (36) of a turbocharger (18), having a turbocharger unit (18) having a turbine (20) and a compressor (36), and a compressor wheel (42) located inside the compressor (36). The present invention also includes a mixing pipe (52) located inside an intake tube (44) for receiving exhaust gas with droplets (54) from an EGR-tube (46), wherein the EGR-tube (46) delivers the exhaust gas with droplets (54) to the mixing pipe (52), mixing the air (41) and the exhaust gas with droplets (54) forming a mixture (64) containing droplets (50), and introducing the mixture (64) and the droplets (50) onto the compressor wheel (42) in an area of low circumferential speed, preventing damage to the compressor wheel (42).

Abstract: The invention relates to a method for the production of a pharmaceutical composition for treating cancer by combining Parapoxvirus ovis with at least one anticancer agent. The invention furthermore relates to a method for treating a patient afflicted with cancer comprising the administration of Parapoxvirus ovis in combination with at least one anticancer agent.

Abstract: An engine assembly (10) comprising an engine, a plurality of coolers, a plurality of bypasses, and at least one actuator (32). The engine has an exhaust manifold and an intake manifold. The gaseous fluid exiting the exhaust manifold is recirculated to the intake manifold. The exhaust gas passes through either an air cooler or a bypass. At least one actuator is operably connected to the plurality of bypasses. The bypasses have a valve (28, 30) which is actuated to control the flow of the gaseous fluid through the bypass as both the bypass and the cooler. Therefore, when a single actuator is used to control the valves in both bypasses, the valves in the bypasses have the same relationship with the inlets so that a single actuator movement will control both valves in the same manner.

Abstract: The present invention is an exhaust gas recirculation system for a motor vehicle, having a turbocharger unit (18) which has a turbine (20) and a compressor (36), the compressor (36) having a compressor wheel (42) which rotates on an axis (66). There is also a dispersion apparatus (56) operably associated with a condensation separation apparatus (58). The condensation separation apparatus (58) separates moisture from exhaust gas flowing from the turbine (20), and the dispersion apparatus (56) reintroduces the moisture into the compressor (36) in proximity to the compressor wheel axis (66), preventing erosion of the compressor wheel (42).

Abstract: The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.

Abstract: The present application relates to novel tetrahydroquinoline derivatives, to a process for their preparation, to their use on their own or in combination for treating and/or preventing diseases and to their use for preparing medicaments, in particular as inhibitors of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinemias, dyslipidemias, hypertriglyceridemias, hyperlipidemias, hypercholesterolemias and arteriosclerosis.

Abstract: The present application relates to pyrimidinecarboxylic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, in particular dyslipidaemias and arteriosclerosis.

Abstract: Disclosed are compounds and derivatives thereof their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.

Abstract: The invention relates to compounds of the formulae

Abstract: A valve assembly for use in an air management assembly having an engine, an exhaust side, and an intake side, where the valve assembly provides a housing, a plurality of openings in the housing, a valve in the housing, and an actuator operably connected to the valve. The housing is in fluid communication with the exhaust side and the intake side. The plurality of openings in the housing form at least one inlet and at least one outlet in the housing. The valve moves with respect to the plurality of openings.

Abstract: A method for monitoring and diagnosing an air charger system for use in an engine assembly having pre-existing sensors, having the steps of providing an air charger having a turbine and a compressor operatively coupled to one another. Providing a control unit for monitoring a plurality of operating conditions of the engine assembly. The control unit calculates an expected value of a selected operating condition based upon at least another of the plurality of operating conditions. Comparing the expected value and at least another of the plurality of operating conditions. Diagnosing a fault condition, if present, based upon the expected value and said at least another of said plurality of operating conditions being outside a predetermined tolerance.

Abstract: An adsorption element for adsorbing gases and vapors from the gaseous atmosphere in the intake tract of an internal combustion engine. The adsorption element is disposed within a wall of a flow cross section carrying the intake air, has a planar adsorption medium along which the intake air flows, and is pleated to create folds in longitudinal direction of the intake stream.

Abstract: The present invention relates to novel compounds, to a process for their preparation and to their use as medicaments, in particular as antiviral medicaments.