Abstract: There is provided an assay device comprising a lid and a base, said base comprising, a sample addition zone, a reaction zone and an absorbing zone, said components being in fluid connection and being part of a fluid passage leading from the sample addition zone to the absorbing zone, wherein: (a) a sample addition well is integrated in the lid, (b) the absorbing zone consists of an area on an non-porous substrate, having substantially perpendicular projections, said projections defining a volume, which together with the volume of the fluid passage defines the sample volume subjected to the assay, and (c) at least one filter is between the sample addition well and the sample addition zone. There is further provided methods for handling samples.

Abstract: An optical reader for an optical assay arrangement including a polymeric sample substrate having a reaction-site surface provided with protruding microstructures and at least one reaction-site area; a light source for illuminating the reaction-site area; and a detector device for detecting light emitted from the reaction-site area. The light source is arranged to inject exciting light rays into the polymeric sample substrate with a controlled angle of incidence such that the protruding microstructures guide the exciting light rays in the direction of the reaction-site area, and the detector device detects light emitted from the at least one reaction-site area.

Abstract: A power supply system includes an AC input configured to be coupled to an AC source, an AC output configured to be coupled to a load, a UPS having an input coupled to the AC input and an output coupled to the AC output and a bypass circuit coupled between the AC input and the AC output and configured to open and close a bypass path therebetween. The system further includes a controller configured to control the UPS and the bypass circuit such that the UPS operates as an online UPS for a first input voltage magnitude condition at the AC input and as a standby UPS for a second input voltage magnitude condition at the AC input. A multi-mode converter may be coupled to a DC link of the UPS and configured to be selectively coupled to a battery and the AC input to respectively support battery conversion and current control at the AC input in respective first and second modes of operation of the UPS.

Abstract: A power distribution system includes an uninterruptible power supply (UPS) and a power distribution unit including a plurality of interconnected and/or interconnectable guarded connectors coupled to an output of the UPS. Each of the guarded connectors is configured to mate with a guarded connector of a power distribution cable. The power distribution unit may further include a load terminal connected or connectable to the guarded connectors.

Abstract: Manufacturing of miniaturised three-dimensional electric components are presented, as well as components manufactured by the methods. The manufacturing methods comprise micro-replication of at least one master structure, e.g. via a mould structure, in at least one polymer layer onto which layer at least one conductive path is provided.

Abstract: Fluorescence reader (10) for an optical assay arrangement comprising a polymeric sample substrate (1) having a reaction site-surface and a substrate surface (3), the fluorescence reader comprising a light source (5) arranged to illuminate the reaction site-surface through the substrate surface, and a detector device (6) arranged to detect fluorescent light emitted from said reaction site-surface and transmitted through the substrate surface, the substrate surface provided with total-internal-reflection suppressing means (15).

Abstract: A power supply system includes an AC input configured to be coupled to an AC source, an AC output configured to be coupled to a load, a UPS having an input coupled to the AC input and an output coupled to the AC output and a bypass circuit coupled between the AC input and the AC output and configured to open and close a bypass path therebetween. The system further includes a controller configured to control the UPS and the bypass circuit such that the UPS operates as an online UPS for a first input voltage magnitude condition at the AC input and as a standby UPS for a second input voltage magnitude condition at the AC input. A multi-mode converter may be coupled to a DC link of the UPS and configured to be selectively coupled to a battery and the AC input to respectively support battery conversion and current control at the AC input in respective first and second modes of operation of the UPS.

Abstract: Manufacturing of miniaturized three-dimensional electric components are presented, as well as components manufactured by the methods. The manufacturing methods comprise micro-replication of at least one master structure, e.g. via a mould structure, in at least one polymer layer onto which layer at least one conductive path is provided.

Abstract: Method of manufacturing a microscale nozzle, comprising the steps of forming a microscale channel in the top surface of a substrate, said microscale channel comprising an inlet end and a nozzle-end, depositing a nozzle-forming layer in a section of the microscale channel, and removing material from the substrate at the nozzle-end of the microscale channel to expose at least a portion of said nozzle-forming layer. The manufactured microscale nozzle may be used for transferring a liquid sample form a microchip fluidic system into an external analytical device.

Abstract: The invention comprises a polymeric microarray support (1) for an optical assay arrangement (2) comprising optical means (3, 4, 6) for detection of light emitted from the support. The microarray support is provided with microfeatures comprising a surface enlarging pattern (5), i.e. grooves having a selected depth (8). The depth is selected such that the sum of the depth and of the variations in the thickness (7) of the support substantially corresponds to the depth of focus of the optical means.

Abstract: A nozzle chip (3) for ejecting a liquid such as in an electrospray device is built from a substrate chip having grooves (5, 7) on a top surface. A lid (25) is attached to the top surface closing the grooves to form channels one of which has an open outlet end (9). At the outlet end a nozzle is formed at or attached and it has an outlet opening from which the liquid is to be ejected. Alignment recesses (13, 15) are made at edges of the substrate chip and they are accurately positioned in relation to the outlet opening, the alignment recesses allowing an accurate mounting of nozzle chip giving the outlet opening of the nozzle a reproducible position in the device where it is to be used. At the outlet end a recess (17) in the substrate chip can be provided and the nozzle can then be located in the recess to mechanically protect it.

Abstract: The invention relates to a matrix suitable for use in the replication of a plastic element having a positive microstructure, comprising a first wear-resistant layer that is supported by a carrier element, wherein the matrix comprises a heating means for supplying electrical heat energy through the wear-resistant layer or carrier element. The invention further relates to a plastic element producing machine and a method for the manufacture of a plastic element having a surface with a positive microstructure.

Abstract: A power distribution system includes an uninterruptible power supply (UPS) and a power distribution unit including a plurality of interconnected and/or interconnectable guarded connectors coupled to an output of the UPS. Each of the guarded connectors is configured to mate with a guarded connector of a power distribution cable. The power distribution unit may further include a load terminal connected or connectable to the guarded connectors.

Abstract: The present invention relates to a method for the manufacture of a matrix, and a matrix manufactured in accordance with the method. The matrix (2) is in the form of a mould-cavity insert provided with a negative microstructure (2a) on its surface, which microstructure is reproducible in a plastic material (3) as positive microstructure (3a) in a machine used. The matrix shall be capable of displaying different microstructures (51?:1, 51?:2, 52?:1) on different surface sections where the selected microstructures originate from different manufacturing processes for originals used.

Abstract: The invention relates to a matrix suitable for use in the replication of a plastic element having a positive microstructure, comprising a first wear-resistant layer that is supported by a carrier element, wherein the matrix comprises a heating means for supplying electrical heat energy through the wear-resistant layer or carrier element. The invention further relates to a plastic element producing machine and a method for the manufacture of a plastic element having a surface with a positive microstructure.

Abstract: The invention relates to a micro fluidic system comprising a substrate, and, provided on said substrate, at least one flow path interconnecting with functional means in which liquid samples can be treated by desired procedures. The flow paths are laid out to form a pattern for the transport of liquid samples to and from said functional means. These flow paths comprise a plurality of micro posts protruding upwards from said substrate, the spacing between the micro posts being small enough to induce a capillary action in a liquid sample applied anywhere within any of said flow paths, so as to force said liquid to move from where said liquid sample was applied.

Abstract: A method of producing a plastic product having a microstructured surface (3a), utilizing an arrangement for moulding plastic products. Said arrangement has at least two mould parts (2, 3) movable towards and away from each other, a predetermined volume of a viscous polymerizable plastic material (9) being supplied to a cavity formed between the mould parts, after which polymerization of the plastic material occurs. After said polymerization of the plastic material (9′), the mould parts are caused to move apart from each other thereby allowing removal of a finished plastic product the outer shape of which conforms to the shape of the cavity produced by the mould parts. Said viscous polymerizable plastic material (9) is supplied to the cavity (6) around a hole (10a) pertaining to the finished plastic product, and said viscous plastic material is distributed in a direction from said hole (10a) towards the peripheral edge area of the plastic product.

Abstract: Manufacturing of miniaturised three-dimensional electric components are presented, as well as components manufactured by the methods. The manufacturing methods comprise micro-replication of at least one master structure, e.g. via a mould structure, in at least one polymer layer onto which layer at least one conductive path is provided.

Abstract: Method of manufacturing a microscale nozzle (52), comprising the steps of forming a microscale channel (32) in the top surface (34) of a substrate (30), said microscale channel (32) comprising an inlet end (36) and a nozzle-end (38), depositing a nozzle-forming layer (50) in a section of the microscale channel (32), removing material from the substrate (30) at the nozzle-end (38) of the microscale channel (32) to expose at least a portion of said nozzle-forming layer (50). The manufactured microscale nozzle may be used for transferring a liquid sample form a microchip fluidic system into an external analytical device. Whereby the transfer is performed by droplet, spray or steam.

Abstract: Dispensing nozzle (15), comprising an essentially flat base member (17) having two essentially parallel surfaces. At least one fluid channel (16) is provided therein with an inlet opening and an outlet opening. The channel is oriented substantially perpendicularly in relation to the general extension of the base member (15). A surface surrounding at least one of said openings has a high wetting angle for the fluid to be dispensed.